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IslandViewer 4: expanded prediction of genomic islands for larger-scale datasets

Claire Bertelli, Matthew R Laird, Kelly P Williams, Britney Y Lau, Gemma Hoad, Geoffrey L Winsor, Fiona SL Brinkman
2017 Nucleic Acids Research  
doi:10.1093/nar/gkx343 pmid:28472413 pmcid:PMC5570257 fatcat:roma4nul5vctjk2ef4pu4u32iq

Effect of bread gluten content on gastrointestinal function: a crossover MRI study on healthy humans

Marina Coletta, Fred K. Gates, Luca Marciani, Henna Shiwani, Giles Major, Caroline L. Hoad, Gemma Chaddock, Penny A. Gowland, Robin C. Spiller
2015 British Journal of Nutrition  
AbstractGluten is a crucial functional component of bread, but the effect of increasing gluten content on gastrointestinal (GI) function remains uncertain. Our aim was to investigate the effect of increasing gluten content on GI function and symptoms in healthy participants using the unique capabilities of MRI. A total of twelve healthy participants completed this randomised, mechanistic, open-label, three-way crossover study. On days 1 and 2 they consumed either gluten-free bread (GFB), or
more » ... al gluten content bread (NGCB) or added gluten content bread (AGCB). The same bread was consumed on day 3, and MRI scans were performed every 60 min from fasting baseline up to 360 min after eating. The appearance of the gastric chime in the images was assessed using a visual heterogeneity score. Gastric volumes, the small bowel water content (SBWC), colonic volumes and colonic gas content and GI symptoms were measured. Fasting transverse colonic volume after the 2-d preload was significantly higher after GFB compared with NGCB and AGCB with a dose-dependent response (289 (sem96)v. 212 (sem74)v. 179 (sem87) ml, respectively;P=0·02). The intragastric chyme heterogeneity score was higher for the bread with increased gluten (AGCB 6 (interquartile range (IQR) 0·5) compared with GFB 3 (IQR 0·5);P=0·003). However, gastric half-emptying time was not different between breads nor were study day GI symptoms, postprandial SBWC, colonic volume and gas content. This MRI study showed novel mechanistic insights in the GI responses to different breads, which are poorly understood notwithstanding the importance of this staple food.
doi:10.1017/s0007114515004183 pmid:26522233 fatcat:3iubyotdxbf3pjvws2j7ggpz5q

Distinct Abnormalities of Small Bowel and Regional Colonic Volumes in Subtypes of Irritable Bowel Syndrome Revealed by MRI

Ching Lam, Gemma Chaddock, Luca Marciani Laurea, Carolyn Costigan, Eleanor Cox, Caroline Hoad, Susan Pritchard, Penny Gowland, Robin Spiller
2016 American Journal of Gastroenterology  
interpretation of data, statistical analysis, administrative and material support, study supervision: Ching Lam; recruitment of participants into study, study supervision, acquisition and analysis of data: Gemma  ...  statistical analysis and technical support: Luca Marciani Laurea; technical support: Carolyn Costigan; technical support: Eleanor Cox; study concept and design, technical support, analysis of data: Caroline Hoad  ... 
doi:10.1038/ajg.2016.538 pmid:27958282 pmcid:PMC5318666 fatcat:yykdjl7gnzfx5mckuakj6cf2se

Improvements to services at the European Nucleotide Archive

Rasko Leinonen, Ruth Akhtar, Ewan Birney, James Bonfield, Lawrence Bower, Matt Corbett, Ying Cheng, Fehmi Demiralp, Nadeem Faruque, Neil Goodgame, Richard Gibson, Gemma Hoad (+17 others)
2009 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www .ebi.ac.uk/ena) is Europe's primary nucleotide sequence archival resource, safeguarding open nucleotide data access, engaging in worldwide
doi:10.1093/nar/gkp998 pmid:19906712 pmcid:PMC2808951 fatcat:7hx2okpxtbdcvpeoabj2q5emhe

Acknowledgments [chapter]

2020 Naked Agency  
Hoad agreed to work with me. Shared with humor, his direct questions and incisive comments pushed me toward stimulating theoretical terrains.  ...  Sheppard, Stacey Langwick, Pamela Gilbert, Nancy Worman, Karmen MacKendrick, Gemma Angel, Gloria Chan-Sook Kim, Ricardo A.  ... 
doi:10.1515/9781478007579-001 fatcat:rtj4m4hnsvhhbmhd3osmuzym2m

Growth-promoting effects of sustained swimming in fingerlings of gilthead sea bream (Sparus aurata L.)

Josefina Blasco, A. Moya, A. Millán-Cubillo, E. J. Vélez, E. Capilla, J. Pérez-Sánchez, J. Gutiérrez, J. Fernández- Borrás
2015 Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology  
We analysed growth and body indexes, plasma IGF-I and GH levels, feed conversion, composition (proximate and isotopic ( 15 N/ 13 C)) and metabolic key enzymes (COX, CS, LDH, HOAD, HK, ALAT, ASAT) of white  ...  However, there are some conflicting results relating to muscle HOAD activity after training; endurance training in the brook trout increases HOAD activity in red and white muscles, which would indicate  ...  During the five-weeks experimental period, both groups were fed by hand with a commercial diet (Gemma Diamond, Skretting) three times per day (7 a.m., 2 p.m. and 10 p.m.) until apparent satiety.  ... 
doi:10.1007/s00360-015-0933-5 pmid:26391594 fatcat:llt7p56c5rcpncnidnz3nfngai

Does a cannibal feeding strategy impart differential metabolic performance in young burbot (Lota lota maculosa)?

Amanda J Frazier, Nathan R Jensen, Shawn P Young, Anne E Todgham, Steven Cooke
2020 Conservation Physiology  
In comparison to the commercial diet containing 14-15% lipid and 59-62% protein (GEMMA Micro, Skretting USA, UT, USA), a cannibal diet may be higher in protein and lower in lipid content.  ...  Non-cannibals had a significantly higher HOAD/CS ratio on average than cannibals.  ... 
doi:10.1093/conphys/coaa034 pmid:32391152 pmcid:PMC7196671 fatcat:5ou62sztnfexlhugfzk332rthy

Potential capacity of Senegalese sole ( Solea senegalensis ) to use carbohydrates: Metabolic responses to hypo- and hyper-glycaemia

Marta Conde-Sieira, José L. Soengas, Luísa M.P. Valente
2015 Aquaculture  
Fish were fed once daily (09:00 h) to satiety with commercial dry fish pellets (GEMMA DIAMOND 1.8 produced by SKRETTING; proximate composition was 62% crude protein, 9% carbohydrates, 16% crude fat  ...  As for the activity of enzymes involved in lipid metabolism, we observed an increase in HOAD 4h after glucose administration, whereas no changes were observed in G6PDH.  ... 
doi:10.1016/j.aquaculture.2014.12.042 fatcat:y4wjbkjvtzc5xfhy2uchyqsx4y

Page 482 of Florida Bar Journal Vol. 74, Issue 8 [page]

2000 Florida Bar Journal  
B2 E Little Canada MN 55117-1567 ALLEN, David 6,Jr . 305/2730755 1 1349 SW 84TH Ln Miami 331 73-4223 ALLEN, Gemma Bndget ... 3126533000 Three First National Plaza 70 W Madison St Ste 2715 Chicago IL 60602  ...  ALLAN, Charles K . 941/261-1087 Bldg 5 Apt 109 180 Turtle Lake Ct Naples 34105-5565 ALLEN, Alee Arm 404,6437075 12110 Brookfield Club Dr Roswell GA 30075-1264 ALLEN, Craiq Ethan . 612/7630552 1 80 County Hoad  ... 

ニホンナシ長果枝の花芽形成における植物ホルモンの役割とその利用による制御技術
The roles of plant hormones in the regulation of flower bud formation of Japanese pear, and the use of the hormones in the pear production

Akiko Ito
2001 Regulation of Plant Growth & Development  
V , Hoad , Acta Hort. ,120, 131 ( 1981) J. Rakllgan, H . Gemma and S . Iwahori , Jpn. J. Trop. Agr . , 39 ,1 ( 1995 )Y . Mor a 冂d N . Zicslin , Hort. 尺 ev . , 9, 53 q987 )L . 亅 . Edgerton und M . B .  ...  V , Hoad , Acta " ort . , 80 , 93 ( 1978 ) M . G . Cline , The Botanical Review . 57, 318 ( 199t) K . E , Parker , Physiol , Plant . ,82, 477 ( 1991)L , M . S .  ... 
doi:10.18978/jscrp.36.1_80 fatcat:ddvevkofhrhmvfderhhq4ti3n4

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

Paul A. Northcott, David J. H. Shih, John Peacock, Livia Garzia, A. Sorana Morrissy, Thomas Zichner, Adrian M. Stütz, Andrey Korshunov, Jüri Reimand, Steven E. Schumacher, Rameen Beroukhim, David W. Ellison (+123 others)
2012 Nature  
PAN and MDT co-conceived the study. PAN, MAM, and MDT led the study. PAN planned and executed experiments and analyses, supervised data acquisition, performed bioinformatic analyses, and extracted nucleic acids for the MAGIC cohort. DJHS led the bioinformatics and performed analyses. JP performed quantitative RT-PCR and Sanger sequencing of PVT1 fusions, expression profiled PVT1-encoded miRNAs, and generated schematics for PVT1 fusion genes. LG performed the MYC and miR-1204 knockdown
more » ... s. SM supervised the RNASeq and WGS experiments and performed data analysis. TZ, AMS, and JOK performed the large insert paired-end sequencing and PCR verification of SNCAIP duplication samples. AK performed interphase FISH and IHC for candidate genes. JR and GBD led the pathway analyses and generated enrichment plots. SES and RB provided technical support with the GISTIC2 bioinformatic platform. DWE performed interphase FISH for candidate genes.
doi:10.1038/nature11327 pmid:22832581 pmcid:PMC3683624 fatcat:l75eyfc2uzektdrmawquzkfe6m

Recombinant Bovine Growth Hormone-Induced Metabolic Remodelling Enhances Growth of Gilthead Sea-Bream (Sparus aurata): Insights from Stable Isotopes Composition and Proteomics

Josefina Blasco, Emilio J. Vélez, Miquel Perelló-Amorós, Sheida Azizi, Encarnación Capilla, Jaume Fernández-Borràs, Joaquim Gutiérrez
2021 International Journal of Molecular Sciences  
They were fed ad libitum (near 10% body weight/day) five times a day with a commercial diet (Gemma Diamond Skretting, Burgos, Spain).  ...  HOAD (3-hydroxyacyl CoA dehydrogenase, E.C 1.1.1.35): 71.4 mM imidazole buffer (pH 8.0), 2 mM NADH, 2 mM acetoacetyl-CoA (substrate).  ... 
doi:10.3390/ijms222313107 pmid:34884912 pmcid:PMC8658469 fatcat:2p7kmwypqzchrk5kddua7sep6m

The power of the treacherous interpreter: Multilingualism in Jacques Audiard's Un prophète

Gemma King
2013 Linguistica Antverpiensia, New Series – Themes in Translation Studies  
According to Hoad in his aforementioned article, while "French… is the lingua franca in the prison… it is Malik's fluency in other languages that drives the plot, and his rise to power" (2010).  ...  As Hoad explains in his 2010 Guardian article "A Prophet Shows Us a Multilingual Future for Cinema", "the film catches the dark side of language-its relationship to power; it can be a badge of belonging  ... 
doi:10.52034/lanstts.v0i13.51 fatcat:liwbtntvyrcwtpt3nyv6mazudq

Listeria Membrane Protrusion Collapse: Requirement of Cyclophilin A for Listeria Cell-to-Cell Spreading

Aaron S Dhanda, Katarina T Lulic, A Wayne Vogl, Margaret M Mc Gee, Robert H Chiu, Julian A Guttman
2018 Journal of Infectious Diseases  
We also thank Jonathan Choy and Ashani Montgomery as well as Fiona Brinkman and Gemma Hoad for assistance with the revisions of this manuscript. Financial support.  ... 
doi:10.1093/infdis/jiy255 pmid:29733369 fatcat:qngrxxo6abaxvacy254htbcy2y

Study of the Consequences of Global Warming in Water Dynamics During Dormancy Phase in Temperate Zone Fruit Crops [chapter]

Robson Ryu, Paulo Celso de Mello-Farias, Fabiano Simes, Flavio Gilberto
2012 Global Warming - Impacts and Future Perspectives  
Gemma for skilful help, Ms. N.M. Nishihata for assist the edition of MR images.  ...  ., 1983; Mullins & Rajasekaran, 1981; Ramirez & Hoad, 1981; Stephan et al., 1999) , mineral nutrients (Golomp & Goldschmidt, 1981; Hartmann et al., 1966; Priestly, 1977) , and flower bud formation in  ...  increase in zeatin levels during the induction period in the off year suggests that had possibly a positive effect on floral formation (Chen, 1987 (Chen, , 1990 Mullins & Rajasekaran, 1981; Ramirez & Hoad  ... 
doi:10.5772/47857 fatcat:2cvv6rfaznairnj2owcijr2myi
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