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Medienkunde + Informatik = ?

Bernd Bethge, Dirk Drews, Ursula Rump, Michael Fothe, Gabor Meißner
2011 GI-Fachtagung Informatik und Schule  
Eine erfolgreiche Implementierungvon Medienkunde an Schulen benötigte inev erbindliches chulinterneP lanung und eine integrativeU msetzung,e ine sinnvolle Verknüpfung medienkundlicher und informatischer Kompetenzen und Inhalte,m edienkompetenteL ehrerkollegien,e ines ystematische und kontinuierli-cheLehreraus-und -fortbildung sowieguteRahmenbedingungen. 1 Einführung Wer sich heutzutage mitM edienb efasst,n utzt häufig Computer.D iesi st einerd er Gründe fürd ie Fortentwicklung desT hüringer
more » ... enkunde-Konzeptes in denJ ahren 2009/10.N eben den bekannten Themen,d ie schoni n der Handreichung von 2001 für denKursder Klassenstufen5bis7enthaltenw aren,w erdeninformatisches Basiswissen, derJ ugendmedien-u nd Datenschutzs owie dasU rheberrechts tärker als bisher betont ([Th09]; [LM08]; [GI08]). Künftig istder Kurs Medienkundeauchf ür dieKlassenstufen 8 bis10 vorgesehen. DieU msetzung derneuen Konzeptionhat im Schuljahr 2009/10an denw eiterführendenS chulen begonnen. In diesem Aufsatz werden dieneueKonzeption und dieb egleitendeF ortbildungb eschrieben und wesentliche Ergebnisse einerL ehrerbefragungzusammengefasst.Konsequenzen werden abgeleitet. DerKursMedienkunde wird integrativ in denU nterrichtsfächernunterrichtet(derzeitam häufigsten in denF ächern Deutsch, Kunsterziehung, Mathematik,E nglisch und Geografie).M edien, Medieneinsatzi nd er Schule,C omputeru nd Informatik sind inzwischen derart verwoben,d asss iche in Zusammenführen dieser Bereiche nahezu aufdrängt. Thüringen hats ichf ür einenK ursM edienkunde entschieden. Für einP flichtfach "Informatik"o der" Informatik und Medien" in derS ekundarstufe Ig ibte sa uchw eiter-hinguteArgumente ([GI08], [Fo10],[Br10]).
dblp:conf/schule/BethgeDRFM11 fatcat:xugsb6fywfcq7id6hch46wbk3y

Influence of promoter DNA topology on sequence-specific DNA binding and transactivation by tumor suppressor p53

Ella Kim, Gabor Rohaly, Stefan Heinrichs, Dimitri Gimnopoulos, Hildegard Meißner, Wolfgang Deppert
1999 Oncogene  
promote or prohibit sequence speci®c DNA binding of p53, are an important feature in orchestrating the activation of dierent p53 responsive promoters.
doi:10.1038/sj.onc.1203139 pmid:10602486 fatcat:zbmtelpf2zabherx6p3dlgamxq

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain

Andrea Stutz, Carl-Christian Kolbe, Rainer Stahl, Gabor L. Horvath, Bernardo S. Franklin, Olivia van Ray, Rebecca Brinkschulte, Matthias Geyer, Felix Meissner, Eicke Latz
2017 Journal of Experimental Medicine  
NLRP3 is a cytosolic pattern recognition receptor that senses microbes and endogenous danger signals. Upon activation, NLRP3 forms an inflammasome with the adapter ASC, resulting in caspase-1 activation, release of proinflammatory cytokines and cell death. How NLRP3 activation is regulated by transcriptional and posttranslational mechanisms to prevent aberrant activation remains incompletely understood. Here, we identify three conserved phosphorylation sites in NLRP3 and demonstrate that NLRP3
more » ... ctivation is controlled by phosphorylation of its pyrin domain (PYD). Phosphomimetic residues in NLRP3 PYD abrogate inflammasome activation and structural modeling indicates that phosphorylation of the PYD regulates charge–charge interaction between two PYDs that are essential for NLRP3 activation. Phosphatase 2A (PP2A) inhibition or knock-down drastically reduces NLRP3 activation, showing that PP2A can license inflammasome assembly via dephosphorylating NLRP3 PYD. These results propose that the balance between kinases and phosphatases acting on the NLRP3 PYD is critical for NLRP3 activation.
doi:10.1084/jem.20160933 pmid:28465465 pmcid:PMC5460996 fatcat:atkcrbuw3zfvlc7tu2uajpilky

Protecting and restoring Europe's waters: An analysis of the future development needs of the Water Framework Directive

Laurence Carvalho, Eleanor B. Mackay, Ana Cristina Cardoso, Annette Baattrup-Pedersen, Sebastian Birk, Kirsty L. Blackstock, Gábor Borics, Angel Borja, Christian K. Feld, Maria Teresa Ferreira, Lidija Globevnik, Bruna Grizzetti (+14 others)
2019 Science of the Total Environment  
Editor: Damia Barcelo The Water Framework Directive (WFD) is a pioneering piece of legislation that aims to protect and enhance aquatic ecosystems and promote sustainable water use across Europe. There is growing concern that the objective of good status, or higher, in all EU waters by 2027 is a long way from being achieved in many countries. Through questionnaire analysis of almost 100 experts, we provide recommendations to enhance WFD monitoring and assessment systems, improve programmes of
more » ... asures and further integrate with other sectoral policies. Our analysis highlights that there is great potential to enhance assessment schemes through strategic design of monitoring networks and innovation, such as earth observation. New diagnostic tools that use existing WFD monitoring data, but incorporate novel statistical and trait-based approaches could be used more widely to diagnose the cause of deterioration under conditions of multiple pressures and deliver a hierarchy of solutions for more evidence-driven decisions in river basin management. There is also a growing recognition that measures undertaken in river basin management should deliver multiple benefits across sectors, such as reduced flood risk, and there needs to be robust demonstration studies that evaluate these. Continued efforts in 'mainstreaming' water policy into other policy sectors is clearly needed to deliver wider success with WFD goals, particularly with agricultural policy. Other key policy areas where a need for stronger integration with water policy was recognised included urban planning (waste water treatment), flooding, climate and energy (hydropower). Having a deadline for attaining the policy objective of good status is important, but even more essential is to have a permanent framework for river basin management that addresses the delays in implementation of measures. This requires a long-term perspective, far beyond the current deadline of 2027.
doi:10.1016/j.scitotenv.2018.12.255 fatcat:fmupjdnti5fkzf3a6apajecjjy

Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Concomitant Intracranial Hemorrhage

Johannes M. Weller, Julius N. Meissner, Sebastian Stösser, Franziska Dorn, Gabor C. Petzold, Felix J. Bode, A. Reich, O. Nikoubashman, J. Röther, B. Eckert, M. Braun, G. F. Hamann (+32 others)
2022 Clinical Neuroradiology  
Purpose Intravenous thrombolysis and mechanical thrombectomy (MT) are standard of care in patients with acute ischemic stroke due to large vessel occlusion. Data on MT in patients with intracranial hemorrhage prior to intervention is limited to anecdotal reports, as these patients were excluded from thrombectomy trials. Methods We analyzed patients from an observational multicenter cohort with acute ischemic stroke and endovascular treatment, the German Stroke Registry—Endovascular Treatment
more » ... al, with intracranial hemorrhage before MT. Baseline characteristics, procedural parameters and functional outcome at 90 days were analyzed and compared to a propensity score matched cohort. Results Out of 6635 patients, we identified 32 patients (0.5%) with acute ischemic stroke due to large vessel occlusion and preinterventional intracranial hemorrhage who underwent MT. Risk factors of intracranial hemorrhage were head trauma, oral anticoagulation and intravenous thrombolysis. Overall mortality was high (50%) but among patients with a premorbid modified Rankin scale (mRS) of 0–2 (n = 15), good clinical outcome (mRS 0–2) at 90 days was achieved in 40% of patients. Periprocedural and outcome results did not differ between patients with and without preinterventional intracranial hemorrhage. Conclusion Preinterventional intracranial hemorrhage in acute ischemic stroke patients with large vessel occlusion is rare. The use of MT is technically feasible and a substantial number of patients achieve good clinical outcome, indicating that MT should not be withheld in patients with preinterventional intracranial hemorrhage.
doi:10.1007/s00062-021-01128-9 pmid:34989816 fatcat:mz5kcskjxvhgdhn7d6lwhuqpsa

Page 105 of Psychological Abstracts Vol. 39, Issue 1 [page]

1965 Psychological Abstracts  
Meissner. 937. Horvath, Laszl6 Gabor. A pszichomotoros teljesitéképességre tett placebo hatasok kisérletes vizsgalata.  ...  Meissner. 932. Glick, B. S. Inadequacies in the reporting of clinical drug research.  ... 

Page 536 of Psychological Abstracts Vol. 40, Issue 5 [page]

1966 Psychological Abstracts  
Meissner. 5676. McGuire, M. T., Stein, S., & Mendelson, J. H. (Dept.  ...  ., & Gabor, I. Ein Verbrechen in Pondex-Psychose. [A crime committed during Pondex- psychosis.] Psychiatrie, Neurologie und medizinische Psychologie, 1965, 17(12), 474-477.  ... 

iii) 流動層型

Kunio Yoshida
1972 Chemical engineering  
J, 17, 252 (1971) 85) Gabor, J. D.: I and EC, Fund., 8, 84 (1969) 86) Gabor, J. D. and LB. Koppel : Chem. Eng. Progr. Sym.  ...  Sci., 21, 731 (1966) 45) Gabor, J. D.: Proc. Int. Sym. on Fluidization, Eindhoven, p.230, Netherlands Univ. Press (1967) 46) Gabor, J. D.: Chem. Eng.  ... 
doi:10.1252/kakoronbunshu1953.36.713 fatcat:oxccuyn7njbwdeihxybylj36fa

DNAqua-Net: Developing new genetic tools for bioassessment and monitoring of aquatic ecosystems in Europe

Florian Leese, Florian Altermatt, Agnès Bouchez, Torbjørn Ekrem, Daniel Hering, Kristian Meissner, Patricia Mergen, Jan Pawlowski, Jeremy Piggott, Frédéric Rimet, Dirk Steinke, Pierre Taberlet (+89 others)
2016 Research Ideas and Outcomes  
doi:10.3897/rio.2.e11321 fatcat:mz6pvzv345d3zpwrsh2cqkdjta

Sliding Test by Using an Apparatus Imitating a Human Finger for Estimating the Tactile Sensation of Cosmetic Foundation

Keita HORIUCHI, Ken NAKANO
2007 Journal of Advanced Mechanical Design, Systems, and Manufacturing  
The signal of the spring deflection was analyzed by wavelet analysis by using the Gabor wavelet as the mother wavelet.  ...  sensation when the Meissner corpuscles are stimulated by the frictional vibration.  ... 
doi:10.1299/jamdsm.1.726 fatcat:phuz4uwakrc7vhktxei6pt33ra

Rheologentagung 2003 Meeting of the German Society of Rheology

Dietmar Auhl, Marcus Heindl
2003 Applied Rheology  
Meissner, and Prof. Mielke. Figure 4 4 Figure 4 (left above): Prof. Mielke and his organizing team, Mrs. Richter und Mrs. Alibegovic (left) at the reception.  ...  Gabor (Darmstadt). After a short coffee break the meeting continued with two lectures in the field melt rheology, which were given by D. Auhl (Erlangen) and D. Schulze (Freiburg).  ... 
doi:10.1515/arh-2003-0027 fatcat:cq5seosvkfbjnew7uwwmnsecb4

Fundamentals and Applications of Electron Holography [chapter]

Akira Tonomura
2011 Holography, Research and Technologies  
Gabor (Gabor, 1949) : an electron hologram is formed as an interference pattern between an object wave and a reference wave, and the object electron wave is reconstructed as an optical wave by illuminating  ...  Gabor intended to optically compensate for the aberrations in the electron lens system, a factor limiting the resolution of electron microscopes.  ... 
doi:10.5772/14280 fatcat:4xcj2dyqpvgfpafrfktkavfehe

Page 281 of Abstracts of Photographic Science and Engineering Literature Vol. 8, Issue 9 [page]

1969 Abstracts of Photographic Science and Engineering Literature  
1759/69P EVTUHOV Vv 1621/69 EYMANN J O 1523/69 FAERMAN G P 1531/69 FERRIER WG 1680/69 FOURNEY M E 1669/69 FRIEDMAN P J 1683/69 FROUMIN R 1634/69 GABOR D 1662769 1663/69 GARRISON J 8B 1684/69 GAUDYN T J  ...  1685/69 1628/69 1569/69P MARECHAL C # MARTIN R E MARTYNENKO O V MATKIN JH mc CaMY CS MC CURRY E M MC MULLAN J T MC VEIGH P A MECKL H MEHARG L S MEIER R W MEINHARDT G MEISSNER H D MENZEL K H MENZEL R MERCER  ... 

Recently published papers: small pieces of the puzzle and the long-term view

Jonathan Ball
2003 Critical Care  
Meissner and coworkers [15] have stolen a march on the manufacturers of novel agents by conducting a successful trial of enteral naloxone in ventilated patients.  ...  Gabor and colleagues [18] added to this field by investigating what contribution environmental stimuli make to sleep disruption in both normal individuals and mechanically ventilated patients.  ... 
doi:10.1186/cc2328 pmid:12793868 pmcid:PMC270692 fatcat:ww4uxhsu7feojoeepdoh4fzmya

Page 436 of Psychological Abstracts Vol. 46, Issue 2 [page]

1971 Psychological Abstracts  
., 3615 Meislin, Jack, 3281 Meissner, W. W., 3180 Mejia, Berta, 3449 Melikian, L.. 2835 Meliska, Charles J., 2473 Mellenbergh, G.  ...  2289 Pakkenberg, H., 2395 Palermo, David S., 2332 Palffy, Zoltan, 2145 Palhegyi, Ferenc, 2104 Pallas, Janet R., 2198 Palmer, Richard J., 3823 Palmer, Stephen E., 2290 Palmore, Erdman B., 2787 Palotas, Gabor  ... 
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