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GPCRDB: an information system for G protein-coupled receptors

F Horn
<span title="1998-01-01">1998</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
Recent developments in G protein -coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific  ...  foundation for drug design studies.  ...  ACKNOWLEDGEMENT The COST Actional CM1207 'GLISTEN' has generously hosted the biannual GPCRdb meetings and supported multiple research visits.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/26.1.275">doi:10.1093/nar/26.1.275</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/9399852">pmid:9399852</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC147194/">pmcid:PMC147194</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/yor7cqlgmjdwvjogxsfpwuay4q">fatcat:yor7cqlgmjdwvjogxsfpwuay4q</a> </span>
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GPCRdb: an information system for G protein-coupled receptors

Vignir Isberg, Stefan Mordalski, Christian Munk, Krzysztof Rataj, Kasper Harpsøe, Alexander S. Hauser, Bas Vroling, Andrzej J. Bojarski, Gert Vriend, David E. Gloriam
<span title="2016-12-06">2016</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
For the past 20 years, the GPCRDB (G proteincoupled receptors database; http://www.gpcr.org/ 7tm/) has been a 'one-stop shop' for G proteincoupled receptor (GPCR)-related data.  ...  The GPCRDB also provides visualization and analysis tools, plus a number of query systems.  ...  ACKNOWLEDGEMENTS Andrius Senulis, Frantisek Sudzina and Magnus Vesterager Larsen are acknowledged for programming contributions and Kimberley Fidom for the annotation of GPCR crystal structures.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkw1218">doi:10.1093/nar/gkw1218</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27923934">pmid:27923934</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5389621/">pmcid:PMC5389621</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6tfaxevq2fewtfz73765zmpgie">fatcat:6tfaxevq2fewtfz73765zmpgie</a> </span>
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GPCRdb: an information system for G protein-coupled receptors

Vignir Isberg, Stefan Mordalski, Christian Munk, Krzysztof Rataj, Kasper Harpsøe, Alexander S. Hauser, Bas Vroling, Andrzej J. Bojarski, Gert Vriend, David E. Gloriam
<span title="2015-11-17">2015</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
Recent developments in G protein-coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific  ...  foundation for drug design studies.  ...  ACKNOWLEDGEMENT The COST Actional CM1207 'GLISTEN' has generously hosted the biannual GPCRdb meetings and supported multiple research visits.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkv1178">doi:10.1093/nar/gkv1178</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26582914">pmid:26582914</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4702843/">pmcid:PMC4702843</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ljkr6qpbm5fvrnlozadbfwntcm">fatcat:ljkr6qpbm5fvrnlozadbfwntcm</a> </span>
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GPCRDB: an information system for G protein-coupled receptors

Vignir Isberg, Bas Vroling, Rob van der Kant, Kang Li, Gert Vriend, David Gloriam
<span title="2013-12-03">2013</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
Recent developments in G protein-coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific  ...  foundation for drug design studies.  ...  ACKNOWLEDGEMENT The COST Actional CM1207 'GLISTEN' has generously hosted the biannual GPCRdb meetings and supported multiple research visits.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkt1255">doi:10.1093/nar/gkt1255</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24304901">pmid:24304901</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3965068/">pmcid:PMC3965068</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rx7hy6i3rvdzdme3prj73erdk4">fatcat:rx7hy6i3rvdzdme3prj73erdk4</a> </span>
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GPCRDB information system for G protein-coupled receptors

F. Horn
<span title="2003-01-01">2003</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
The GPCRDB is a molecular class-specific information system that collects, combines, validates and disseminates heterogeneous data on G proteincoupled receptors (GPCRs).  ...  The GPCRDB is updated automatically once every 4-5 months and is freely accessible at  ...  F.H. and F.E.C. acknowledge the NIH for support.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkg103">doi:10.1093/nar/gkg103</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/12520006">pmid:12520006</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC165550/">pmcid:PMC165550</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ainl4hz5nrd33awwog32akrrei">fatcat:ainl4hz5nrd33awwog32akrrei</a> </span>
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GPCRDB: information system for G protein-coupled receptors

B. Vroling, M. Sanders, C. Baakman, A. Borrmann, S. Verhoeven, J. Klomp, L. Oliveira, J. de Vlieg, G. Vriend
<span title="2010-11-02">2010</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
Recent developments in G protein-coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific  ...  foundation for drug design studies.  ...  ACKNOWLEDGEMENT The COST Actional CM1207 'GLISTEN' has generously hosted the biannual GPCRdb meetings and supported multiple research visits.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkq1009">doi:10.1093/nar/gkq1009</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21045054">pmid:21045054</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3013641/">pmcid:PMC3013641</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/osdipws46vbonmp4jphxsfzyxe">fatcat:osdipws46vbonmp4jphxsfzyxe</a> </span>
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GPCRdb: the G protein-coupled receptor database - an introduction

C Munk, V Isberg, S Mordalski, K Harpsøe, K Rataj, A S Hauser, P Kolb, A J Bojarski, G Vriend, D E Gloriam
<span title="2016-06-03">2016</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wsc2264oo5gpvk5scotezp75pu" style="color: black;">British Journal of Pharmacology</a> </i> &nbsp;
Molecular GPCRDB: an information system for G protein-coupled receptors. modelling of G protein-coupled receptors through the web.  ...  GPCRdb: an information system for G protein-coupled The authors declare no conflicts of interest. receptors.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/bph.13509">doi:10.1111/bph.13509</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27155948">pmid:27155948</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4919580/">pmcid:PMC4919580</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6ggwl72qrnam7l75j5gx5bjeim">fatcat:6ggwl72qrnam7l75j5gx5bjeim</a> </span>
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Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems

F. Horn
<span title="2001-01-01">2001</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
These are the GPCRDB and NucleaRDB information systems, which collect and disseminate data related to G protein-coupled receptors and intranuclear hormone receptors, respectively.  ...  The NucleaRDB was started recently as an application of the concept for the generalization of this technology.  ...  G protein-coupled receptors G protein-coupled receptors (GPCRs) consist of a single protein chain that crosses the membrane seven times.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/29.1.346">doi:10.1093/nar/29.1.346</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/11125133">pmid:11125133</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC29816/">pmcid:PMC29816</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zupticzgifhuljearoncktv6wi">fatcat:zupticzgifhuljearoncktv6wi</a> </span>
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GPCRdb in 2021: integrating GPCR sequence, structure and function

Albert J Kooistra, Stefan Mordalski, Gáspár Pándy-Szekeres, Mauricio Esguerra, Alibek Mamyrbekov, Christian Munk, György M Keserű, David E Gloriam
<span title="2020-12-03">2020</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hfp6p6inqbdexbsu4r7usndpte" style="color: black;">Nucleic Acids Research</a> </i> &nbsp;
G protein-coupled receptors (GPCRs) form both the largest family of membrane proteins and drug targets, mediating the action of one-third of medicines.  ...  GPCRdb contains all human non-olfactory GPCRs (and &gt;27 000 orthologs), G-proteins and arrestins.  ...  similarity, structure superposition and site search tools GPCRdb: an information system for G protein-coupled receptors Isberg V et al. 2016 Nucleic Acids Research (33) Structure constructs  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkaa1080">doi:10.1093/nar/gkaa1080</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33270898">pmid:33270898</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mh56tghzpjhtna3a4ddwrply4e">fatcat:mh56tghzpjhtna3a4ddwrply4e</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210104053311/https://watermark.silverchair.com/gkaa1080.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAqIwggKeBgkqhkiG9w0BBwagggKPMIICiwIBADCCAoQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM8zXhMBtWHF3gm-w3AgEQgIICVeVhe5q3pXGDbnTKkuV7CiNpnnefs-QVDZjnnCjsG5uRMXNYvUti4e3ke5oQgaNz7YvAnq9nqJA7wbppAs-PPM8p7s6bSboXWUmUReI0UiFAWcUTPJLWzhTLvAIFtVGs0irtiieJjbrcaFtxNSLCHLuC5Lrt3GfvXGcGLCSAwYU1PhrkGnWPgURiSx6DcXr2iXTIGMvgSaB5REXHC1X8G_u07sTMhCw_JZpEO_xgJ7r5xcoa4kYB0zW7mulM773-8QKGxi2jiuwRRx1U5ft4dZynSxnUOIIE4ZvB98g-AByl1c_nDMVjF9devIlsYekYJE5kAYc-Wp2saMR5VgBXA1b9zqtMBuN8HcgzekOmZmUGtk19xcgtQpyr5MoWnu_IfWfPFpov-BnXbV285-35sSKDinh4G4cdW2kEpJO1xoFb1sf71LZUua1xZkWbbe1AABh-C13-ZtyqVgsFJfSSQgRDgDimAURqE4bK9lWyJslUCdSu3XJn7z6BH-I82tO6JTVtyN1vjBgWJ6XfB0VqL75Y-sl1Cwh93Uqbct-jl7YtKRGB0DXY7m1MNtfESSPukHEJNvXxa1thKDzJ_f2EVKRxz3019ABcBBvf0aDWKDj67ReHCQ270rbqdjZb2ft5dXPvT3cI84kldq5sMXo6UrH_LEHBkQiGwTBKd3MM9bLSkNiTHxtRYhMEMGEeSmAG2TyStmKeYHnFkFOXKJChwOVqcnylAD5oj4DNPdMKPDP2XB-4pPmII0JGzU5VQ7xxEVsf06ujxEJkjjkzDiFTBHiLEmAmqg" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/3b/b5/3bb550b1d48f32e37bdd40be8660db22bbf07e49.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/nar/gkaa1080"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a>

The design of query interfaces to the GPCRDB biological database

D. Che, K. Aberer, Y. Chen
<span title="">1999</span> <i title="IEEE"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kiejf773kfapvdfgqletuf4bqq" style="color: black;">Proceedings User Interfaces to Data Intensive Systems</a> </i> &nbsp;
In this paper, we describe the query interfaces of a practical biological database system -GPCRDB.  ...  Distinguishing features of the system include: an embedded smart query engine (for query relaxation), smooth integration of navigation with the more conventional SQL-based query mechanisms, and the top-down  ...  The authors are very glad to acknowledge that Hannelore Eisner has did a lot of implementation work in the GPCRDB query system.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1109/uidis.1999.791459">doi:10.1109/uidis.1999.791459</a> <a target="_blank" rel="external noopener" href="https://dblp.org/rec/conf/uidis/CheAC99.html">dblp:conf/uidis/CheAC99</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ceyv5e73sfalzb6u2argnyxeze">fatcat:ceyv5e73sfalzb6u2argnyxeze</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170818085710/https://infoscience.epfl.ch/record/54375/files/P1999-13.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/0a/cb/0acbaa3653e1c5a11ff8e53ddb02554453a122f1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1109/uidis.1999.791459"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> ieee.com </button> </a>

Coding GPCR-G protein specificity

Sebastian GB Furness, Patrick M Sexton
<span title="2017-07-11">2017</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/dtytuhrzcbdsbixdngpw3dnxfy" style="color: black;">Cell Research</a> </i> &nbsp;
Not only does the GPCR-α5 helix interaction appear to be required for G protein activation but it also has an undisputed role in GPCR-G protein specificity, as the exchange of this C-terminal fragment  ...  These conformational differences may be important for differential G protein coupling and are likely to alter nucleotide exchange [9, 10] .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/cr.2017.92">doi:10.1038/cr.2017.92</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28695889">pmid:28695889</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ff65gkckrndzxitqinhhsvgrci">fatcat:ff65gkckrndzxitqinhhsvgrci</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200511110218/https://www.nature.com/articles/cr201792.pdf?error=cookies_not_supported&amp;code=dd715a91-00a1-49ff-b7ea-9ac069a95fa4" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b2/d8/b2d8abfb3b4de88d5a99454f4415d27ccf19b725.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/cr.2017.92"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

George Khelashvili, Kevin Dorff, Jufang Shan, Marta Camacho-Artacho, Lucy Skrabanek, Bas Vroling, Michel Bouvier, Lakshmi A. Devi, Susan R. George, Jonathan A. Javitch, Martin J. Lohse, Graeme Milligan (+7 others)
<span title="2010-05-25">2010</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4r72gbmtcrde5no3fwwogjs3cu" style="color: black;">Computer applications in the biosciences : CABIOS</a> </i> &nbsp;
Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically.  ...  GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature.  ...  We also thank Dr Andrea Bortolato for retrieving the first batch of relevant papers for system population. Conflict of Interest: none declared.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/bioinformatics/btq264">doi:10.1093/bioinformatics/btq264</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20501551">pmid:20501551</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2894509/">pmcid:PMC2894509</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6x44wjbvurcfhlr3xo3k2uwaoy">fatcat:6x44wjbvurcfhlr3xo3k2uwaoy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20151113181706/http://pharmacology.case.edu/department/faculty/primary/pages/Palczewski/articles/1804.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ae/b5/aeb53e9af6bfd7637d8d1856ec8ad380e145a204.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/bioinformatics/btq264"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> oup.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894509" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Integrating GPCR-specific information with full text articles

Bas Vroling, David Thorne, Philip McDermott, Teresa K Attwood, Gert Vriend, Steve Pettifer
<span title="">2011</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/n5zrklrhlzhtdorf4rk4rmeo3i" style="color: black;">BMC Bioinformatics</a> </i> &nbsp;
With the continued growth in the volume both of experimental G protein-coupled receptor (GPCR) data and of the related peer-reviewed literature, the ability of GPCR researchers to keep up-to-date is becoming  ...  Results: We present work that integrates the biological data and annotations in the GPCR information system (GPCRDB) with next-generation methods for intelligently exploring, visualising and interacting  ...  We thank Rob Leurs for stimulating discussions.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1471-2105-12-362">doi:10.1186/1471-2105-12-362</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21910883">pmid:21910883</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3179973/">pmcid:PMC3179973</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/uwv5xwkkcjh7hposn2a2s6qpja">fatcat:uwv5xwkkcjh7hposn2a2s6qpja</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210428223610/https://repository.ubn.ru.nl/bitstream/handle/2066/91939/1/91939.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/62/54/6254dc70aa907897b1ac66b4ce7381645ca01f92.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1471-2105-12-362"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179973" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

GPCR-PEnDB: a database of protein sequences and derived features to facilitate prediction and classification of G protein-coupled receptors

Khodeza Begum, Jonathon E Mohl, Fredrick Ayivor, Eder E Perez, Ming-Ying Leung
<span title="2020-11-20">2020</span> <i title="Oxford University Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ejkvir3kzbdojf5kygupkidsca" style="color: black;">Database: The Journal of Biological Databases and Curation</a> </i> &nbsp;
G protein-coupled receptors (GPCRs) constitute the largest group of membrane receptor proteins in eukaryotes.  ...  Each protein is linked to information about its source organism, classification, sequence lengths and composition, and other derived sequence features.  ...  Acknowledgements The authors thank Anastasia Kellogg and Kyle Long for their contributions to the initial data collection and the preliminary design of the database and Gerardo Cardenas for his help with  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/database/baaa087">doi:10.1093/database/baaa087</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33216895">pmid:33216895</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7678784/">pmcid:PMC7678784</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/tq6n2erlazgkbik76adagqvhb4">fatcat:tq6n2erlazgkbik76adagqvhb4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201209060424/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7678784&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/39/ee/39eee8ad07ee8093a0b8a67d4d2a8cbb94172d99.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/database/baaa087"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678784" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Coevolution underlies GPCR-G protein selectivity and functionality

Min Jae Seo, Joongyu Heo, Kyunghui Kim, Ka Young Chung, Wookyung Yu
<span title="2021-04-12">2021</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tnqhc2x2aneavcd3gx5h7mswhm" style="color: black;">Scientific Reports</a> </i> &nbsp;
AbstractG protein-coupled receptors (GPCRs) regulate diverse physiological events, which makes them as the major targets for many approved drugs.  ...  HTR, DAR) and Gα proteins with a coevolutionary tool, statistical coupling analysis.  ...  We used multiple sequence alignments from GPCRdb because they provide well-labeled alignments using the Generic-GPCRdb numbering system by each receptor 16 .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-021-87251-6">doi:10.1038/s41598-021-87251-6</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33846507">pmid:33846507</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/l6rxanvk5zatvpblw46a3azn3u">fatcat:l6rxanvk5zatvpblw46a3azn3u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210718161028/https://www.nature.com/articles/s41598-021-87251-6.pdf?error=cookies_not_supported&amp;code=a3891b37-7c2f-42e5-b281-044f269d2d57" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2f/9a/2f9af404e54ba4e559a966639683189ea11e43ae.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-021-87251-6"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>
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