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An informatics project and online "Knowledge Centre" supporting modern genotype-to-phenotype research

Adam J. Webb, Gudmundur A. Thorisson, Anthony J. Brookes
2011 Human Mutation  
So far, however, no such tool has existed for the genotype-phenotype field in general-an oversight the G2P Knowledge Centre seeks to address.  ...  repository, and comprehensive data access portal.  ... 
doi:10.1002/humu.21469 pmid:21438073 fatcat:ktr4z662qbbcri2etel6ooz73i

Plant Genebanks: Present Situation and Proposals for Their Improvement. the Case of the Spanish Network

María José Díez, Lucía De la Rosa, Isaura Martín, Luís Guasch, María Elena Cartea, Cristina Mallor, Joan Casals, Joan Simó, Ana Rivera, German Anastasio, Jaime Prohens, Salvador Soler (+3 others)
2018 Frontiers in Plant Science  
; insufficient phenotyping, genotyping, and epiphenotyping; unsatisfactory rate of use by end users; and, insufficient funding.  ...  Current advances in biotechnology, and especially those in gene editing will have without doubt an impact on the role of genebanks.  ...  Orzaez, and P. Puigdomenech.  ... 
doi:10.3389/fpls.2018.01794 pmid:30564263 pmcid:PMC6288731 fatcat:4dui7u4t7fgg7hhxtb5exnr4py

D8.2 Overview Document on Already Existing Data Harmonisation Tools

Sebastian Mate, Ines Leb, Christina Schüttler, Kaisa Silander, Timo Miettinen, Juha Knuuttila, Niina Eklund, Hans-Ulrich Prokosch
2016 Zenodo  
Since data harmonisation, however, is not only an important issue in biobanking, but a key component in all data sharing/data projects, our focus is also on such projects outside the biobanking area.  ...  In addition, it will include information on the different levels and versions of various standardised and non-standardised ontologies and data dictionaries and schemas.  ...  GEN2PHEN GEN2PHEN is a project that "aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system  ... 
doi:10.5281/zenodo.165775 fatcat:gv3654h5ondpri6hbuo2hdppeq

Bioinformatics and statistical genomics

2008 Genomic Medicine  
Intein data obtained from InBase Intein database.  ...  production and target detection etc.  ...  (7) Creation of a 'G2P Knowledge Centre' providing information exchange solutions, search/ analysis tools, and support for primary data and comment deposition (8) Deployment of GEN2PHEN solutions to the  ... 
doi:10.1007/s11568-009-9081-x pmid:19488836 pmcid:PMC2694866 fatcat:kmyq6l3qefdhpaz5zsi6eyc37m

Eleventh International Congress on Drug Therapy in HIV Infection

2012 Journal of the International AIDS Society  
We also gladly receive inquiries on sponsorship and donations to support open access publications from authors in low-and middle-income countries.  ...  Supplements The Journal of the International AIDS Society publishes supplements, special issues and thematic series on own  ...  Based on the HIV-GRADE internet-tool an online tool was developed to make the rule set easily accessible and usable.  ... 
doi:10.7448/ias.15.6.18447 fatcat:o6ztvyqlbfcrbduzn7v5iehkxe

Abstracts for Supplement

2010 International Journal of Infectious Diseases  
The knowledge of CCHFV pathogenesis is improving: recently, new target cells were identified.  ...  Data on practices in management of patients with suspected malaria before and after the training were collected and compared.Data on out patient consultations for 10 consecutive days in the pre and post  ...  A newly discovered viral enzyme capable of alteration of nucleic acid structure via phosphotriester and phosphodiester bonding complex: An event leading to a new frontier of research and development for  ... 
doi:10.1016/j.ijid.2010.02.002 fatcat:dkj62aswgjfzfo5z5jktl2rvhu

Bioinformatical approaches to ranking of anti-HIV combination therapies and planning of treatment schedules [article]

André Altmann, Universität Des Saarlandes, Universität Des Saarlandes
These depend on information regarding the treatment composition, the viral genotype, features of viral evolution, and the patient's therapy history.  ...  We address the problem of extending purely data-driven approaches to support novel drugs with little available data.  ...  Acknowledgements Material and Methods Data The data for this study originate from four publications.  ... 
doi:10.22028/d291-25993 fatcat:j6c5nsupl5e5pnm5ackm4kvhg4