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Fusion in diffusion MRI for improved fibre orientation estimation: An application to the 3T and 7T data of the Human Connectome Project

Stamatios N. Sotiropoulos, Moisés Hernández-Fernández, An T. Vu, Jesper L. Andersson, Steen Moeller, Essa Yacoub, Christophe Lenglet, Kamil Ugurbil, Timothy E.J. Behrens, Saad Jbabdi
2016 NeuroImage  
Considering these trade-offs, the Human Connectome Project (HCP) acquires high quality dMRI data for the same subjects at different field strengths (3T and 7T), which are publically released.  ...  Due to differences in the signal behavior and in the underlying scanner hardware, the HCP 3T and 7T data have complementary features in k- and q-space.  ...  Acknowledgement We acknowledge support from the Human Connectome Project (1U54MH091657-01), from the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research, Biotechnology  ... 
doi:10.1016/j.neuroimage.2016.04.014 pmid:27071694 pmcid:PMC6318224 fatcat:xkddrrhddvaczkpinwh5kv6wi4

Advances in diffusion MRI acquisition and processing in the Human Connectome Project

Stamatios N. Sotiropoulos, Saad Jbabdi, Junqian Xu, Jesper L. Andersson, Steen Moeller, Edward J. Auerbach, Matthew F. Glasser, Moises Hernandez, Guillermo Sapiro, Mark Jenkinson, David A. Feinberg, Essa Yacoub (+4 others)
2013 NeuroImage  
The Human Connectome Project (HCP) is a collaborative 5-year effort to map human brain connections and their variability in healthy adults.  ...  In this overview, we focus on diffusion MRI (dMRI) and the structural connectivity aspect of the project.  ...  Acknowledgments We acknowledge support from the Human Connectome Project (1U54MH091657-01), from the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research, plus grants  ... 
doi:10.1016/j.neuroimage.2013.05.057 pmid:23702418 pmcid:PMC3720790 fatcat:3e3hkqbzdjcmtnx4anwqp3swvi

In vivo super-resolution track-density imaging for thalamic nuclei identification [article]

Gianpaolo Antonio Basile, Salvatore Bertino, Alessia Bramanti, Giuseppe Pio Anastasi, Demetrio Milardi, Alberto Cacciola
2021 bioRxiv   pre-print
We tested this protocol on i) six healthy individual 3T MRI scans from the Human Connectome Project database, and on ii) a group population template reconstructed by averaging 100 unrelated healthy subjects  ...  The development of novel techniques for the in vivo, non-invasive visualization and identification of thalamic nuclei has represented a major challenge for human neuroimaging research in the last decades  ...  Then, we test this approach on a population-level template derived from diffusion MRI data of 100 healthy subjects from the Human Connectome Project (HCP) ).  ... 
doi:10.1101/2021.01.03.425122 fatcat:73v5nybxyra4rh35lbisgbjqqq

2014 Biennial Meeting of the American Society for Stereotactic and Functional Neurosurgery. Washington, D.C., USA, May 31-June 3, 2014: Abstracts

2014 Stereotactic and Functional Neurosurgery  
Here we describe data mining of structural and behavioral data from the Human Connectome Project to identify potential targets for DBS for the treatment of drug addiction.  ...  Here we use task-fMRI data mined from the Human Connectome Project to validate that activity in the nucleus accumbens changes in response reward cues during a gambling task.  ... 
doi:10.1159/000363530 pmid:24902536 fatcat:f3ptvsfgnfat7osvq5gugpk4gq

17th Quadrennial Meeting of the World Society for Stereotactic and Functional Neurosurgery. Berlin, Germany, June 26-29, 2017: Abstracts

2017 Stereotactic and Functional Neurosurgery  
Modeled lesions were used as seed regions for deterministic tractography on an 842-subject diffusion data template from HCP in order to identify involved connectomic networks.  ...  Imaging data consisted of high-resolution anatomical T1W and T2W MRI sequences (3T, Philips Intera, Best, Netherlands) and 32-direction diffusion tensor imaging.  ...  Hemifacial pain and sensory change following occipital neuralgia may be a symptomatic clue in decision of the exploration of GON.  ... 
doi:10.1159/000478281 pmid:28641280 fatcat:ivcbjloukfgiriry65t37fccm4

2014 Joint ACTRIMS-ECTRIMS Meeting (MSBoston 2014) MS Journal Online: Poster Session 1

2014 Multiple Sclerosis  
Demographic data was recollected. Zarit Burden Interview (ZBI) was administered to caregivers and Expanded Disability Status Scale (EDSS) was calculated in each patient.  ...  Results: Some degree of caregiver burden was found in 60.6%, being moderate or severe in 31.1%. The "Impact of caregiving" subdimension accounted for most weight of the construct.  ...  Methods: Thirty-one patients (5 Early MS, 16 RRMS, 10 SPMS) underwent a modified version of the MACFIMS battery; 7T multi-echo T2* imaging (0.33×0.33×1 mm 3 ) for T2* maps; 3T MRI for acquisition of T1  ... 
doi:10.1177/1352458514546077 pmid:25205048 pmcid:PMC4244172 fatcat:tzd6co2dijebfasgp6htmug2um

ACNP 58th Annual Meeting: Panels, Mini-Panels and Study Groups

2019 Neuropsychopharmacology  
Efforts toward in vivo application of both technologies are ongoing. Disclosure: Nothing to disclose. Abstract not included.  ...  The Influence of Periphery-To-Brain Communication in Alzheimer's Disease Abstract not included. Abstract not included.  ...  An important first aim is to establish a frame of reference, demonstrating harmonization of our data with the umbrella Human Connectome Project (HCP).  ... 
doi:10.1038/s41386-019-0544-z pmid:31801977 pmcid:PMC6957922 fatcat:hjyvf7fcpbf2fhxit6rlhsvg2y

Development of a Multimodal MRI Study to Characterize Morpho-Functional Features in Rodent Models of Alzheimer's Disease

Daniele Tolomeo
2019
The objective of this work was to develop a multi-modal panel of magnetic resonance imaging (MRI) techniques and automated analysis pipelines, characterized by a high translational impact, in order to  ...  None of the existing biomarkers is simultaneously specific for the pathology and sensitive to its progression.  ...  the frame of the Human Connectome Project, will be adapted to rodent studies.  ... 
doi:10.21954/ou.ro.0000ec2d fatcat:d4iazk2r4vhivfssto46o5sva4