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Towards a Data Hub for Biodiversity with LOD [chapter]

Yoshitaka Minami, Hideaki Takeda, Fumihiro Kato, Ikki Ohmukai, Noriko Arai, Utsugi Jinbo, Motomi Ito, Satoshi Kobayashi, Shoko Kawamoto
2013 Lecture Notes in Computer Science  
Because of a huge variety of biological studies focused on different targets, i.e., from molecules to ecosystem, data produced and used in each field is also managed independently so that it is difficult to know the relationship among them. We aim to build a data hub with LOD to connect data in different biological fields to enhance search and use of data across the fields. We build a prototype data hub on taxonomic information on species, which is a key to retrieve data and link to databases
more » ... different fields. We also demonstrate how the data hub can be used with an application to assist search on other database.
doi:10.1007/978-3-642-37996-3_29 fatcat:27s6visa65c4pldjumxowdof4u

Comparison of mechanical and manual bone marrow puncture needle for intraosseous access; a randomized simulation trial

Fumihiro Ohchi, Nobuyasu Komasawa, Ryosuke Mihara, Toshiaki Minami
2015 SpringerPlus  
During resuscitation, when it is difficult or impossible to establish peripheral venous access, intraosseous route (IO) is considered as an alternative to a central venous line. However, it is sometimes difficult for obtain IO access with conventional manual bone puncture needle. Recently, powered mechanical bone marrow needle was developed. We compared the performance of the manual and mechanical bone marrow puncture needle for adult, child and infant simulation. Methods: 22 anesthesiologists,
more » ... who has never used bone marrow puncture needle, performed manual (Dickman™, Cook Medical) or mechanical (EZ-IO™, Teleflex) bone marrow puncture to simulated adult, child and infant tibia. Puncture success rate, insertion time, and subjective difficulty utilizing visual analogue scale was assessed. Results: In adult settings, with the manual bone marrow needle, only 3 of 22 participants could succeed in the IO route keep, while all participants did in the mechanical bone marrow puncture needle (P < 0.001). In child and infant settings, all trials were successful in both manual and mechanical bone marrow puncture needles (P = 1.00). In adult simulations, IO insertion took significantly longer with manual bone marrow puncture (54.8 ± 15.8 s) than without compressions (3.7 ± 2.1 s; P < 0.001). In child and infant simulations, the IO insertion time was significantly smaller in mechanical trials than in manual ones (child simulation; manual 9.3 ± 4.6 s, mechanical 2.2 ± 0.8 s, P < 0.001, infant simulation; manual 2.0 ± 1.1 s, mechanical 1.5 ± 0.8 s, P = 0.003). Although the VAS score was not significantly higher with manual trials than in mechanical trials among the three simulations (adult simulation, P < 0.001, child simulation, P < 0.001, infant simulation P = 0.006). Conclusions: We conclude that in simulations managed by anesthesiologists who had no clinical experiences with bone marrow puncture, the mechanical bone puncture needle performed better than the manual one for emergency IO route access.
doi:10.1186/s40064-015-0982-y pmid:25977898 pmcid:PMC4422831 fatcat:ytz7toz2ezacbjmldupislwaga

A Method for Minimizing Clock Skew Fluctuations Caused by Interconnect Process Variations

Susumu KOBAYASHI, Fumihiro MINAMI
2013 IEICE transactions on information and systems  
Fumihiro Minami recieved the B.E. and M.E. degrees in 1982 and 1984, respectively, from Tokyo Institute of Technology, Japan. He joined Toshiba Corporation, Kawasaki, Japan, in 1984.  ... 
doi:10.1587/transinf.e96.d.1980 fatcat:yjfutb3qinbb7fadmw6esvtktm

Gate delay estimation in STA under dynamic power supply noise

Takaaki Okumura, Fumihiro Minami, Kenji Shimazaki, Kimihiko Kuwada, Masanori Hashimoto
2010 2010 15th Asia and South Pacific Design Automation Conference (ASP-DAC)  
doi:10.1109/aspdac.2010.5419786 dblp:conf/aspdac/OkumuraMSKH10 fatcat:2raxwylzmrexhloj27t5vrkhy4

A successful case of pediatric tracheal tube exchange utilizing gum-elastic bougie and videolaryngoscope

Fumihiro Ohchi, Noriko Kadono, Toshiaki Minami, Nobuyasu Komasawa
2015 Journal of Pediatric Intensive Care  
doi:10.3233/pic-14086 pmid:31214455 pmcid:PMC6530743 fatcat:j4jbea4dnrf2fmnowpzgbfkxmi

Multiple Mucosa-associated Lymphoid Tissue Lymphoma of the Trachea

Daisuke Minami, Chihiro Ando, Ken Sato, Kaori Moriwaki, Fumihiro Sugahara, Takamasa Nakasuka, Yoshitaka Iwamoto, Keiichi Fujiwara, Takuo Shibayama, Toshiro Yonei, Toshio Sato
2017 Internal medicine (Tokyo. 1992)  
Mucosa-associated lymphoid tissue lymphoma is a common type of primary pulmonary carcinoma, but the presence of polypoid nodules is extremely rare. We herein report two cases with multiple nodules in the trachea. One case involved polypoid nodules and airway stenosis mimicking asthma; the other case had concurrent nontuberculous mycobacterial infection. The diagnosis of both cases was confirmed by bronchoscopy. The two cases were sensitive to radiotherapy and chemotherapy, respectively.
doi:10.2169/internalmedicine.8269-16 pmid:28943536 pmcid:PMC5709637 fatcat:2z7ljpmcifhddmqm5at4lmflrq

High Speed Clock Design beyond 1 GHz Frequency
ギガヘルツの壁を超える 超高速クロック設計技術

FUMIHIRO MINAMI
2001 The Journal of the Institute of Electrical Engineers of Japan  
doi:10.1541/ieejjournal.121.330 fatcat:rai452syaba2xosjxfciube7pa

Gate Delay Estimation in STA under Dynamic Power Supply Noise

Takaaki OKUMURA, Fumihiro MINAMI, Kenji SHIMAZAKI, Kimihiko KUWADA, Masanori HASHIMOTO
2010 IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences  
doi:10.1587/transfun.e93.a.2447 fatcat:hgsk5uafnjhfldtcub4tuylxye

Evaluation of the efficacy of six supraglottic devices for airway management in dark conditions: a crossover randomized simulation trial

Fumihiro Ohchi, Nobuyasu Komasawa, Kentaro Imagawa, Kaori Okamoto, Toshiaki Minami
2015 Journal of Anesthesia  
shaped SGDs may help novice doctors secure the airway under dark conditions.
doi:10.1007/s00540-015-2050-8 pmid:26206177 fatcat:akylznkykjfjncfuvgmgludlmm

Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction

Masahiro Mizuno, Behnoush Khaledian, Masao Maeda, Takanori Hayashi, Seiya Mizuno, Eiji Munetsuna, Takashi Watanabe, Seishi Kono, Seiji Okada, Motoshi Suzuki, Shintaro Takao, Hironobu Minami (+4 others)
2021 Cancers  
Adipose tissue is a component of the tumor microenvironment and is involved in tumor progression. We have previously shown that adipokine adipsin (CFD) functions as an enhancer of tumor proliferation and cancer stem cell (CSC) properties in breast cancers. We established the Cfd-knockout (KO) mice and the mammary adipose tissue-derived stem cells (mADSCs) from them. Cfd-KO in mADSCs significantly reduced their ability to enhance tumorsphere formation of breast cancer patient-derived xenograft
more » ... DX) cells, which was restored by the addition of Cfd in the culture medium. Hepatocyte growth factor (HGF) was expressed and secreted from mADSCs in a Cfd-dependent manner. HGF rescued the reduced ability of Cfd-KO mADSCs to promote tumorsphere formation in vitro and tumor formation in vivo by breast cancer PDX cells. These results suggest that HGF is a downstream effector of Cfd in mADSCs that enhances the CSC properties in breast cancers.
doi:10.3390/cancers13164238 fatcat:36ztasracvghhamhpxkvqf637i

Effect of coronary artery bypass grafting on blood pressure response to head-up tilting

Shinnosuke Hori, Yoshi-ichiro Kamijo, Mitsuru Yuzaki, Tetsuya Kawabe, Kohei Minami, Yasunori Umemoto, Mao Yokoyama, Hiroyasu Uenishi, Yoshiharu Nishimura, Ken Kouda, Yukio Mikami, Fumihiro Tajima
2020 Journal of Physiological Sciences  
Funding This work was funded by Nachikatsuura Research Foundation (L1221; Fumihiro Tajima).  ... 
doi:10.1186/s12576-020-00746-1 pmid:32228438 fatcat:3e6kbfhunbeqhbp6haxnuwa67u

Low-power design methodology for module-wise dynamic voltage and frequency scaling with dynamic de-skewing systems

Takeshi Kitahara, Hiroyuki Hara, Shinichiro Shiratake, Yoshiki Tsukiboshi, Tomoyuki Yoda, Tetsuaki Utsumi, Fumihiro Minami
2006 Proceedings of the 2006 conference on Asia South Pacific design automation - ASP-DAC '06  
doi:10.1145/1118299.1118428 fatcat:ukexpye6cvanthofivr7bzui54

Expression of Notch1 and Numb in small cell lung cancer

Hajime Kikuchi, Jun Sakakibara-Konishi, Megumi Furuta, Hiroshi Yokouchi, Hiroshi Nishihara, Shigeo Yamazaki, Hidetaka Uramoto, Fumihiro Tanaka, Masao Harada, Kenji Akie, Fumiko Sugaya, Yuka Fujita (+14 others)
2017 OncoTarget  
Notch signaling in tumorigenesis functions as an oncogene or tumor suppressor according to the type of malignancy. Numb represses intracellular Notch signaling. Previous studies have demonstrated that Notch signaling suppresses the proliferation of small cell lung cancer (SCLC) cell lines. However, in SCLC, the association between Notch1 and Numb expression and clinicopathological factors or prognosis has remained unclear. In this study, we evaluated the expression of Notch1 and Numb in SCLC.
more » ... immunohistochemically assessed 125 SCLCs that were surgically resected at 16 institutions participating in either the Hokkaido Lung Cancer Clinical Study Group Trial (HOT) or the Fukushima Investigative Group for Healing Thoracic Malignancy (FIGHT) between 2003 and 2013. Correlations between Notch1 or Numb expression and various clinicopathological features were evaluated. Notch1 expression was www.impactjournals.com/oncotarget/ associated with ECOG performance status. Numb expression was associated with age, sex, and pathological histology (SCLC or Combined SCLC). Analysis of cellular biological expression did not demonstrate a significant correlation between the expression of Notch1 and of Numb. Multivariate Cox regression analysis showed that high Notch1 expression was an independent favorable prognostic factor for SCLC(hazard ratio = 0.503, P = 0.023). High Notch1 expression, but not Numb expression, is associated with favorable prognosis in SCLC.
doi:10.18632/oncotarget.14411 pmid:28060745 pmcid:PMC5354663 fatcat:rvinqsmxprckpligqqpufbuduy

A case report of bilateral hypertrophy of coronoid process, diagnosed TMJ-disorder on first examination
初診時に顎関節症と診断された両側性下顎骨筋突起過形成の1症例

Fumihiro YOSHIKAWA, Ken MATSUMOTO, Kinya HIGUCHI, Motohiro TSUJINO, Katsuhiro MINAMI, Yoshihide MORI, Masayoshi SAKUDA
1989 Japanese Journal of Oral & Maxillofacial Surgery  
We report on a rare case of trismus caused by bilateral hypertrophy of the coronoid processes of the mandible. A 13-year old boy presented at our institute complaining of restricted mandible movement. An initial diagnosis of TMJ dysfunction was established, and routine therapy was instituted; however, his condition did not improve. A more thorough examination was undertaken; CT scanning revealed bilateral hyperplasia of the coronoid process. Both coronoid proces were surgically resected.
more » ... s immediately disappeared. The condition appeared due to irritation within the zygomatic arch by the coronoid process.
doi:10.5794/jjoms.35.1242 fatcat:s4yblwclnveexpcwhim5onbq3e

Hemophagocytic syndrome occurred after severe sepsis in a hemodialysis patient: An autopsy case report
血球貪食症候群が敗血症を契機に顕性化した血液透析患者の1剖検例

Tsutomu Koike, Kanako Motoyoshi, Kazuyuki Ryu, Hidenori Yamazaki, Kota Kakeshita, Shinobu Shida, Minami Mizutani, Hayato Fujioka, Yukie Yasumoto, Shiori Shiraishi, Ayako Takashima, Fumihiro Tomoda (+1 others)
2016 Nihon Toseki Igakkai Zasshi  
doi:10.4009/jsdt.49.841 fatcat:c5l3t4gk7jfb5llcocockj564q
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