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From electric circuits to chemical networks

Luca Cardelli, Mirco Tribastone, Max Tschaikowski
2019 Natural Computing  
We describe how to take a linear electric circuit and systematically convert it to a chemical reaction network of the same functionality, as a dynamical system.  ...  This approach provides access to a large library of well-studied devices, from analog electronics, whose chemical network realization can be compared to natural biochemical networks, or used to engineer  ...  The symbols at the left, top, right and bottom of the diagram denote, respectively, a DC voltage source, a resistor, an inductor and the ground From electric circuits to chemical networks 239 o t i ¼ v  ... 
doi:10.1007/s11047-019-09761-7 fatcat:wxfrisptlzer7fg7qp4woir6eu

From Electric Circuits to Chemical Networks [article]

Luca Cardelli, Mirco Tribastone, Max Tschaikowski
2018 arXiv   pre-print
We describe how to take a linear electric circuit and systematically convert it to a chemical reaction network of the same functionality, as a dynamical system.  ...  This approach provides access to a large library of well-studied devices, from analog electronics, whose chemical network realization can be compared to natural biochemical networks, or used to engineer  ...  From a systems biology point of view, we may want to compare the CRNs derived from electric circuits to the ones occurring in nature. This might help elucidate the function of natural networks.  ... 
arXiv:1812.03308v1 fatcat:vzgywyexufc7taci6mkjhdxmnm

Rectifying Electrical Synapses Can Affect the Influence of Synaptic Modulation on Output Pattern Robustness

G. J. Gutierrez, E. Marder
2013 Journal of Neuroscience  
Rectification can have a striking effect on the network's sensitivity to alterations of the strengths of the chemical synapses in the network.  ...  We begin with an electrically coupled circuit of three oscillatory neurons with different starting frequencies, and subsequently add two additional neurons and inhibitory chemical synapses.  ...  The three-cell chain then forms the kernel of the five-cell pattern-generating circuit that we use to explore the dynamics that result from rectification in a network with both electrical and chemical  ... 
doi:10.1523/jneurosci.0937-13.2013 pmid:23926276 pmcid:PMC3735893 fatcat:dqtzn2auunggvh7avpml6tiyzm

Page 32 of The Journal of Chemical Physics Vol. 14, Issue 1 [page]

1946 The Journal of Chemical Physics  
THE JOURNAL OF CHEMICAL PHYSICS VOLUME 14, NUMBER 1 JANUARY, 1946 Network Analyzer Tests of Equivalent Circuits of Vibrating Polyatomic Molecules G. K. CARTER* AND G.  ...  In each case, starting from given constants of the molecular structure, the normal frequencies and modes are measured by means of the equivalent circuit.  ... 

Page 6 of Science Education Vol. 35, Issue 1 [page]

1951 Science Education  
makes it possible to separate a desir- able from an undesirable component, both The ability to see a multiplicity of electric cir- of which are co-existent in the source. cuits in a given network is a  ...  Electric circuits —When electric com- ponents are to be employed for a useful purpose, they are almost always arranged in conductive networks known as circuits.  ... 

Designing voltage multipliers with nanofluidic diodes immersed in aqueous salt solutions

P. Ramirez, V. Gomez, C. Verdia-Baguena, S. Nasir, M. Ali, W. Ensinger, S. Mafe
2016 Physical Chemistry, Chemical Physics - PCCP  
Novel networks composed of asymmetric membranes operate as voltage multipliers and suggest opportunities for the monitoring of sensors and actuators.  ...  Acknowledgements We acknowledge the support from the Ministry of Economic Affairs and Competitiveness and FEDER (project MAT2015-65011-P) and the Generalitat Valenciana (project Prometeo/GV/0069 for Groups  ...  The effect of decreasing, from the balanced to the unbalanced case, the rectification of one of the nanoporous membranes with respect to the others in the network is shown.  ... 
doi:10.1039/c5cp07203d pmid:26771033 fatcat:4h5uf2v6cneynpjwpzjdvt26ea

Prediction of Homo sapiens cancer cells by electrical network modelling of amino acid sequence

Soma Barman, Tanusree Roy
2017 International Journal of Bioinformatics Research and Applications  
The network of amino acid sequence is used to predict the cancer genes by analysing pole-zero distribution and impedance of the network.  ...  In the present paper, electrical network modelling technique is applied on Homo sapiens genes for prediction of cancer disease.  ...  circuit components i.e. resistor, inductor and capacitor.  Analysing the circuit behaviour according to the properties of amino acids.  Modelling electrical network for amino acid string by cascading  ... 
doi:10.1504/ijbra.2017.10002833 fatcat:j5avjezm3bgaxh3zfwqk2taw24

Synchrony and so much more: Diverse roles for electrical synapses in neural circuits

Barry W. Connors
2017 Developmental Neurobiology  
Perhaps electrical synapses are well adapted to some very particular, specialized, yet common function that all neural circuits require?  ...  These characteristics are fairly well conserved across the electrical synapses of all species and brain regions, at least compared to chemical synapses with their multiplicity of transmitters, receptors  ...  Research on electrical synapses from my laboratory was supported by NIH grants NS050434 and NS25983.  ... 
doi:10.1002/dneu.22493 pmid:28245529 pmcid:PMC5395344 fatcat:ojsc6iyqkzccpdefcnnjvu6hha


John R. Koza, William Mydlowec, Guido Lanza, Jessen Yu, Martin A. Keane
2000 Biocomputing 2001  
This paper demonstrates that it is possible to automatically create (reverse engineer) a network of chemical reactions from observed timedomain data.  ...  Recent work has demonstrated that genetic programming is capable of automatically creating complex networks (such as analog electrical circuits and controllers) whose behavior is modeled by linear and  ...  Figure 3 Electrical circuit corresponding to the chemical reaction network. The six triangles in figure 3 represent integrators.  ... 
doi:10.1142/9789814447362_0043 fatcat:6enbmufzurcwzabjn2eupxmive

Multiple Mechanisms Switch an Electrically Coupled, Synaptically Inhibited Neuron between Competing Rhythmic Oscillators

Gabrielle J. Gutierrez, Timothy O'Leary, Eve Marder
2013 Neuron  
We modeled competing fast and slow oscillators connected to a hub neuron with electrical and inhibitory synapses.  ...  These results have importance for interpreting experiments employing optogenetic, genetic, and pharmacological manipulations to understand circuit dynamics.  ...  To evaluate the effect of the electrical synapses on the network dynamics, we forced hn with the total synaptic drive (both electrical and chemical) from the fast and slow oscillators but turned off the  ... 
doi:10.1016/j.neuron.2013.01.016 pmid:23473315 pmcid:PMC3664401 fatcat:c7kmo3pjpfgh7fqfuegm57vhka

The rectification of an electrical synapse can change the functional output of a pattern-generating circuit

Gabrielle J Gutierrez, Eve Marder
2013 BMC Neuroscience  
When the polarity and placement of the rectifying electrical synapse antagonizes the neuron intrinsic properties, one of the rhythmgenerating parts of the circuit is cut off from the rest of the circuit  ...  electrically coupled to both of the rhythm-generating parts of the circuit is an intrinsic oscillator of intermediate frequency (plotted dashed lines represent respective intrinsic frequencies).  ...  For a multi-functional motor network, it is important to be able to switch between stable network patterns by synaptic neuromodulation.  ... 
doi:10.1186/1471-2202-14-s1-p259 pmcid:PMC3704392 fatcat:gkojb6ebkjgb3fi5exef3dvknq

Design of pressure-driven microfluidic networks using electric circuit analogy

Kwang W. Oh, Kangsun Lee, Byungwook Ahn, Edward P. Furlani
2012 Lab on a Chip  
The application of circuit methods to microfluidics is based on the analogous behaviour of hydraulic and electric circuits with correlations of pressure to voltage, volumetric flow rate to current, and  ...  hydraulic to electric resistance.  ...  Acknowledgements This work was supported by grants to K. W. Oh from NSF (ECCS-1002255 and ECCS-0736501) and the Intelligent Microsystems Center at Korea Institute of Science and Technology (KIST).  ... 
doi:10.1039/c2lc20799k pmid:22179505 fatcat:kcuvgsdsynadhon254sb5hwcqm

A physically meaningful equivalent circuit network model of a lithium-ion battery accounting for local electrochemical and thermal behaviour, variable double layer capacitance and degradation

Marie-Therese von Srbik, Monica Marinescu, Ricardo F. Martinez-Botas, Gregory J. Offer
2016 Journal of Power Sources  
A novel electrical circuit analogy is proposed modelling electrochemical systems under realistic automotive operation conditions.  ...  This is the first Equivalent Circuit Network -type model that tracks directly the evolution of species inside the cell.  ...  Acknowledgements The authors would like to thank Yu Merla, Yan Zhao, Mohd Ibthisham Ardani and Ian Hunt for collecting experimental data.  ... 
doi:10.1016/j.jpowsour.2016.05.051 fatcat:uk4y7q7lvbckzbbv3vwwzuqj2u

Decentralized cooling in district heating network: System simulation and parametric study

Seksan Udomsri, Chris Bales, Andrew R. Martin, Viktoria Martin
2012 Applied Energy  
Results show that replacement of the fourth with the fifth generation TDC increases the system electrical COP from 2.64 to 5.27.  ...  The results obtained from parametric studies show that the electrical and thermal COP's, with new realistic boundary conditions, increased from 2.74 to 5.53 and 0.48 to 0.52, respectively for the 4th generation  ...  thermal energy from the two pumps used, and (iii) the driving temperature available from the district heating network is lower than ideal for the TDC.  ... 
doi:10.1016/j.apenergy.2011.10.009 fatcat:td3nfxddfnhfpddyx3uempzjdm

Clarification of electrical current importance in plasma gene transfection by equivalent circuit analysis

Yugo Kido, Hideki Motomura, Yoshihisa Ikeda, Susumu Satoh, Masafumi Jinno, Mohammed Yousfi
2021 PLoS ONE  
cell circuits and analyzed as an electrical network that included a buffer solution and a 96-well plate.  ...  Using this model, we could demonstrate the feasibility of applying equivalent circuit network analysis to calculate electrical factors using fewer components than those required for the finite element  ...  However, to date, there have been no examples of using an electrical network to analyze the spatial distribution of a system with the entire system represented as an equivalent circuit network.  ... 
doi:10.1371/journal.pone.0245654 pmid:33508006 fatcat:jcd2qeo765bkjj76arupfx3sgm
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