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In Reply: The Coronavirus Disease 2019 Global Pandemic: A Neurosurgical Treatment Algorithm
2020
Neurosurgery
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Emergence of Leadership in a Group of Autonomous Robots
2015
PLoS ONE
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In this paper we examine the factors contributing to the emergence of leadership in a group, and we explore the relationship between the role of the leader and the behavioural capabilities of other individuals. We use a simulation technique where a group of foraging robots must coordinate to choose between two identical food zones in order to forage collectively. Behavioural and quantitative analysis indicate that a form of leadership emerges, and that groups with a leader are more effective
doi:10.1371/journal.pone.0137234
pmid:26340449
pmcid:PMC4560398
fatcat:s2q4wacmdvgcbioudwx4pzsot4
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... n groups without. Moreover, we show that the most skilled individuals in a group tend to be the ones that assume a leadership role, supporting biological findings. Further analysis reveals the emergence of different "styles" of leadership (active and passive).
Characteristics of Patients Returning to Work After Brain Tumor Surgery
2021
Frontiers in Human Neuroscience
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Copyright © 2021 Schiavolin, Mariniello, Broggi, Acerbi, Schiariti, Franzini, Di Meco, Ferroli and Leonardi. ...
doi:10.3389/fnhum.2020.609080
pmid:33613204
pmcid:PMC7886680
fatcat:wbpleaeur5fkdowsg6wec76abq
In Silico Mathematical Modelling for Glioblastoma: A Critical Review and a Patient-Specific Case
2021
Journal of Clinical Medicine
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brain tissue Tumor growth Lipkova J (2019) [38] Integration complementary information from MRI and FET-PET to infer tumor cell density in GBM patient to tailor radiotherapy Individual response to RT Acerbi ...
doi:10.3390/jcm10102169
pmid:34067871
fatcat:nm3livrwjzdg5jkxacxmw7rthm
Ex Vivo Fluorescein-Assisted Confocal Laser Endomicroscopy (CONVIVO® System) in Patients With Glioblastoma: Results From a Prospective Study
2020
Frontiers in Oncology
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WHO
2016)
+/−
Tumor
tissue
Infiltrated
tissue
Tumor tissue
Infiltrated
tissue
+
+
Tumor
tissue
Infiltrated
nervous
tissue
Tumor tissue
Infiltrated tissue
+
+
(Continued)
Acerbi ...
Necrosis
GBM
(IV grade WHO
2016)
+/−
Tumor
tissue
Necrosis
Tumor tissue
Necrosis
+
+
Tumor
tissue
Necrosis
Tumor tissue
Necrosis
Vascular
proliferation
+
+
−
(Continued)
Acerbi ...
Copyright © 2020 Acerbi, Pollo, De Laurentis, Restelli, Falco, Vetrano, Broggi, Schiariti, Tramacere, Ferroli and DiMeco. ...
doi:10.3389/fonc.2020.606574
pmid:33425764
pmcid:PMC7787149
fatcat:erx4uwdz2bf4re66qpumg3xhxi
Motor evoked potentials and bis-guided anaesthesia in image-guided mini-invasive neurosurgery of supratentorial tumors nearby the cortico-spinal tract
2017
Turkish Neurosurgery
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Cordella R, Acerbi F, Broggi M, Vailati D, Nazzi V, Schiariti
M Tringali G, Ferroli P, Franzini A, Broggi G: Intraoperative
neurophysiological monitoring of the cortico-spinal tract in
image-guided ...
17
2.0
12.0
75
50
18
1.6
11.0
65
45
19
1.8
6.0
50
53
20
1.5
5.5
45
51
21
1.5
12.0
50
48
22
1.5
5.0
60
51
23
1.8
6.0
65
45
24
2.2
3.0
60
48
Cordella R, Acerbi ...
doi:10.5137/1019-5149.jtn.20023-17.1
pmid:28758184
fatcat:355q5gn3qrhqpmkk4uztevrflq
The role of indocyanine green videoangiography (ICGV) in surgery of parasagittal meningiomas
2013
Acta Neurochirurgica
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Confocal Laser Microscopy in Neurosurgery: State of the Art of Actual Clinical Applications
2021
Journal of Clinical Medicine
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Acerbi received fees from Carl Zeiss Meditec for lectures at international congresses. ...
Year
Confocal System
Used
Fluorophore
Used (Dosages,
Protocol)
N. of pts
Pathologies
Treated
Main Findings
Sensibility/
Specificity;
Diagnostic
Accuracy
Blinding Level of the
Study
Acerbi ...
doi:10.3390/jcm10092035
pmid:34068592
pmcid:PMC8126060
fatcat:247bzhrvsveifm7rbvd3lcvdee
No Treatment for Small Unruptured Intracranial Aneurysm: Is This the Right Way to Go?
2013
World Neurosurgery
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13) Cordella R, Acerbi F, Marras CE, Carozzi C, Vailati D, Saini M, Tringali G, Ferroli P, Dimeco F, Franzini A, Broggi G. ...
Acta Neurochir Suppl. 2011; 108:197-201. 21) Ferroli P, Acerbi F, Albanese E, Tringali G, Broggi M, Franzini A, Broggi G. ...
doi:10.1016/j.wneu.2013.05.005
pmid:23689129
fatcat:mkc5sdj4ozg3lf2gayi7alyhfu
Clinical Management of Moyamoya Patients
2021
Journal of Clinical Medicine
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Moyamoya angiopathy (MMA) is a peculiar cerebrovascular condition characterized by progressive steno-occlusion of the terminal part of the internal carotid arteries (ICAs) and their proximal branches, associated with the development of a network of fragile collateral vessels at the base of the brain. The diagnosis is essentially made by radiological angiographic techniques. MMA is often idiopathic (moyamoya disease-MMD); conversely, it can be associated with acquired or hereditary conditions
doi:10.3390/jcm10163628
pmid:34441923
pmcid:PMC8397113
fatcat:vfhqaipsuzf7lg7ec3nhdptzty
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... yamoya Syndrome-MMS); however, the pathophysiology underlying either MMD or MMS has not been fully elucidated to date, and this poor knowledge reflects uncertainties and heterogeneity in patient management. MMD and MMS also have similar clinical expressions, including, above all, ischemic and hemorrhagic strokes, then headaches, seizures, cognitive impairment, and movement disorders. The available treatment strategies are currently shared between idiopathic MMD and MMS, including pharmacological and surgical stroke prevention treatments and symptomatic drugs. No pharmacological treatment able to reverse the progressive disappearance of the ICAs has been found to date in both idiopathic and syndromic cases. Antithrombotic agents are usually prescribed in ischemic MMA, although the coexisting hemorrhagic risk should be considered. Surgical revascularization techniques, which are currently the best available treatment in symptomatic MMA, are associated with good long-term outcomes and reduced ischemic and hemorrhagic risks. Given the lack of dedicated randomized clinical trials, current treatment is mainly based on observational studies and physicians' and surgeons' expertise.
Characterisation of biotinylated liposomes for in vivo targeting applications
1993
FEBS Letters
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Liposomes containing monosialoganglioside (G") or polyethylene glycol (PEG) lipid derivatives have prolonged circulation in the blood. This favours liposome extravasation to tumour sites. In this report it is shown that inclusion of G", PEGS,-DPPB or PEGmxrDPPE in liposomes containing biotin-DPPE signiticantly diminished the ability of vesicles to bind to streptavidin in vitro. Steric inhibition due to the bulky head group of these lipids was least for biotin-DPPE liposomes contaming C&i.
doi:10.1016/0014-5793(93)80509-s
pmid:8405439
fatcat:rdzv5unv6ffmfevmyfw7rqtpty
more »
... bu~on studies in CZ6 t~o~-~a~ng mice showed that ~~~-~~sornes containing small amo~ts of biotin-DPPE have long circulation l&-times in the blood. Using fluorescent microscopic techniques, liposomes contaming both G" and biot~-DPPE were detected within ex~-vault spaces in tumours. In addition it was shown that biotin-DPPE in G&iposomes bound streptavidin in situ. These results suggest that G"-liposomes containing biotin-DPPE have potential use as diagnostic or therapeutic reagents in pre-targeting applications dependent on the high-a&&y interaction of biotiu with streptavidin.
Application of an aviation model of incident reporting and investigation to the neurosurgical scenario: method and preliminary data
2012
Neurosurgical Focus
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Drafting the article: Ferroli, Acerbi, Scholtze, Piro. Critically revising the article: Ferroli, Schiariti. Reviewed submitted version of manuscript: all authors. Study supervision: DiMeco. ...
doi:10.3171/2012.9.focus12252
pmid:23116102
fatcat:ymyc5cbfazhzlnun45bvuococi
Fluorescence-Guided Surgery: A Review on Timing and Use in Brain Tumor Surgery
2021
Frontiers in Neurology
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Acerbi et al. found fluorescence in 82% of tumors, including ependymomas, hemangioblastomas, astrocytoma, and a glioneuronal tumor forming rosettes (119) . ...
To date, there are no randomized controlled trials for fluoresceinguided tumor surgery, however, in a recent multicenter phase II study, Acerbi et al. found that fluorescein was safe and effective in HGG ...
Copyright © 2021 Schupper, Rao, Mohammadi, Baron, Lee, Acerbi and Hadjipanayis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
doi:10.3389/fneur.2021.682151
fatcat:5txlrodn2zcqvdyeceutn2hbu4
Trigeminal interfascicular neurolysis (nerve combing) for refractory recurrent neuralgia in multiple sclerosis
2020
Neurosurgical Focus: Video
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In multiple sclerosis (MS) patients, trigeminal neuralgia (TN) represents a challenging syndrome to treat, often refractory to medical therapy and percutaneous techniques. Despite the frequent lack of a neurovascular conflict, the trigeminal nerve's axons are often damaged, with the myelin sheath permanently degenerated, thus explaining the difficulty in treating TN in MS.The authors illustrate trigeminal interfascicular neurolysis (the combing technique) to control refractory recurrent TN in
doi:10.3171/2020.5.focvid203
fatcat:dy4rscyrtvggtjx22tm4axao7m
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... : the nerve is longitudinally divided along its fibers from the root entry zone, determining good pain relief.The video can be found here: https://youtu.be/o1XksPW5fMY
The effect of ozone injection within a common peroneal nerve schwannoma: A mistreatment due to a misdiagnosis
2020
Surgical neurology international
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Peripheral schwannomas can be misdiagnosed or mistreated as they can mimic other subcutaneous lesions, leading to wrong diagnosis and, therefore, to improper treatment. Case Description: A 23-years-old male presented a painful growing nodule at the left popliteal fossa, with distally irradiated pain. A first magnetic resonance imaging depicted a heterogeneous lesion between common peroneal and sural nerves but, surprisingly, the patient was submitted to perilesional injection of ozone-oxygen
doi:10.25259/sni_296_2020
pmid:33365176
pmcid:PMC7749957
fatcat:nnsmeok5brbuhkwmz4xbpf6hau
more »
... ture, causing the onset of intense neuropathic pain. A second MRI showed a morphological change of tumor characteristics. He finally underwent surgery but, intraoperatively, inter-fascicular fibrous adherences were noticed, making the tumor removal more difficult and riskier. The histopathological diagnosis was of schwannoma with areas of foreign body reaction. Conclusion: The injection of ozone or other substances within a subcutaneous swelling should be avoided, before a complete imaging assessment; because of such swelling could be a peripheral nerve schwannoma. The correct assessment of a lesion of the limbs determining radiating pain should be carefully demanded to a thorough history, clinical examination, and appropriate imaging technique. To avoid incorrect management, the treatment of such tumors should be performed in the first place by dedicated equips with proven expertise in this field.
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