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In Reply: The Coronavirus Disease 2019 Global Pandemic: A Neurosurgical Treatment Algorithm

Marco Schiariti, Francesco Restelli, Morgan Broggi, Francesco Acerbi, Paolo Ferroli
2020 Neurosurgery  
doi:10.1093/neuros/nyaa178 pmid:32382731 fatcat:pdkp3d5gpvfytokhfvobvqw4be

Emergence of Leadership in a Group of Autonomous Robots

Francesco Pugliese, Alberto Acerbi, Davide Marocco, Long Wang
2015 PLoS ONE  
In this paper we examine the factors contributing to the emergence of leadership in a group, and we explore the relationship between the role of the leader and the behavioural capabilities of other individuals. We use a simulation technique where a group of foraging robots must coordinate to choose between two identical food zones in order to forage collectively. Behavioural and quantitative analysis indicate that a form of leadership emerges, and that groups with a leader are more effective
more » ... n groups without. Moreover, we show that the most skilled individuals in a group tend to be the ones that assume a leadership role, supporting biological findings. Further analysis reveals the emergence of different "styles" of leadership (active and passive).
doi:10.1371/journal.pone.0137234 pmid:26340449 pmcid:PMC4560398 fatcat:s2q4wacmdvgcbioudwx4pzsot4

Characteristics of Patients Returning to Work After Brain Tumor Surgery

Silvia Schiavolin, Arianna Mariniello, Morgan Broggi, Francesco Acerbi, Marco Schiariti, Angelo Franzini, Francesco Di Meco, Paolo Ferroli, Matilde Leonardi
2021 Frontiers in Human Neuroscience  
Copyright © 2021 Schiavolin, Mariniello, Broggi, Acerbi, Schiariti, Franzini, Di Meco, Ferroli and Leonardi.  ... 
doi:10.3389/fnhum.2020.609080 pmid:33613204 pmcid:PMC7886680 fatcat:wbpleaeur5fkdowsg6wec76abq

In Silico Mathematical Modelling for Glioblastoma: A Critical Review and a Patient-Specific Case

Jacopo Falco, Abramo Agosti, Ignazio G. Vetrano, Alberto Bizzi, Francesco Restelli, Morgan Broggi, Marco Schiariti, Francesco DiMeco, Paolo Ferroli, Pasquale Ciarletta, Francesco Acerbi
2021 Journal of Clinical Medicine  
brain tissue Tumor growth Lipkova J (2019) [38] Integration complementary information from MRI and FET-PET to infer tumor cell density in GBM patient to tailor radiotherapy Individual response to RT Acerbi  ... 
doi:10.3390/jcm10102169 pmid:34067871 fatcat:nm3livrwjzdg5jkxacxmw7rthm

Ex Vivo Fluorescein-Assisted Confocal Laser Endomicroscopy (CONVIVO® System) in Patients With Glioblastoma: Results From a Prospective Study

Francesco Acerbi, Bianca Pollo, Camilla De Laurentis, Francesco Restelli, Jacopo Falco, Ignazio G. Vetrano, Morgan Broggi, Marco Schiariti, Irene Tramacere, Paolo Ferroli, Francesco DiMeco
2020 Frontiers in Oncology  
WHO 2016) +/− Tumor tissue Infiltrated tissue Tumor tissue Infiltrated tissue + + Tumor tissue Infiltrated nervous tissue Tumor tissue Infiltrated tissue + + (Continued) Acerbi  ...  Necrosis GBM (IV grade WHO 2016) +/− Tumor tissue Necrosis Tumor tissue Necrosis + + Tumor tissue Necrosis Tumor tissue Necrosis Vascular proliferation + + − (Continued) Acerbi  ...  Copyright © 2020 Acerbi, Pollo, De Laurentis, Restelli, Falco, Vetrano, Broggi, Schiariti, Tramacere, Ferroli and DiMeco.  ... 
doi:10.3389/fonc.2020.606574 pmid:33425764 pmcid:PMC7787149 fatcat:erx4uwdz2bf4re66qpumg3xhxi

Motor evoked potentials and bis-guided anaesthesia in image-guided mini-invasive neurosurgery of supratentorial tumors nearby the cortico-spinal tract

Roberto Cordella, Eleonora Orena, Francesco Acerbi, Elena Beretta, Dario Caldiroli, Francesco Dimeco, Carla Carozzi
2017 Turkish Neurosurgery  
Cordella R, Acerbi F, Broggi M, Vailati D, Nazzi V, Schiariti M Tringali G, Ferroli P, Franzini A, Broggi G: Intraoperative neurophysiological monitoring of the cortico-spinal tract in image-guided  ...  17 2.0 12.0 75 50 18 1.6 11.0 65 45 19 1.8 6.0 50 53 20 1.5 5.5 45 51 21 1.5 12.0 50 48 22 1.5 5.0 60 51 23 1.8 6.0 65 45 24 2.2 3.0 60 48 Cordella R, Acerbi  ... 
doi:10.5137/1019-5149.jtn.20023-17.1 pmid:28758184 fatcat:355q5gn3qrhqpmkk4uztevrflq

The role of indocyanine green videoangiography (ICGV) in surgery of parasagittal meningiomas

Paolo Ferroli, Francesco Acerbi, Morgan Broggi, Giovanni Broggi
2013 Acta Neurochirurgica  
doi:10.1007/s00701-013-1722-0 pmid:23615801 fatcat:ql4uldelmjhflg6dw2wcgnxrfy

Confocal Laser Microscopy in Neurosurgery: State of the Art of Actual Clinical Applications

Francesco Restelli, Bianca Pollo, Ignazio Gaspare Vetrano, Samuele Cabras, Morgan Broggi, Marco Schiariti, Jacopo Falco, Camilla de Laurentis, Gabriella Raccuia, Paolo Ferroli, Francesco Acerbi
2021 Journal of Clinical Medicine  
Acerbi received fees from Carl Zeiss Meditec for lectures at international congresses.  ...  Year Confocal System Used Fluorophore Used (Dosages, Protocol) N. of pts Pathologies Treated Main Findings Sensibility/ Specificity; Diagnostic Accuracy Blinding Level of the Study Acerbi  ... 
doi:10.3390/jcm10092035 pmid:34068592 pmcid:PMC8126060 fatcat:247bzhrvsveifm7rbvd3lcvdee

No Treatment for Small Unruptured Intracranial Aneurysm: Is This the Right Way to Go?

Francesco Acerbi, Morgan Broggi, Paolo Ferroli
2013 World Neurosurgery  
13) Cordella R, Acerbi F, Marras CE, Carozzi C, Vailati D, Saini M, Tringali G, Ferroli P, Dimeco F, Franzini A, Broggi G.  ...  Acta Neurochir Suppl. 2011; 108:197-201. 21) Ferroli P, Acerbi F, Albanese E, Tringali G, Broggi M, Franzini A, Broggi G.  ... 
doi:10.1016/j.wneu.2013.05.005 pmid:23689129 fatcat:mkc5sdj4ozg3lf2gayi7alyhfu

Clinical Management of Moyamoya Patients

Isabella Canavero, Ignazio Gaspare Vetrano, Marialuisa Zedde, Rosario Pascarella, Laura Gatti, Francesco Acerbi, Sara Nava, Paolo Ferroli, Eugenio Agostino Parati, Anna Bersano
2021 Journal of Clinical Medicine  
Moyamoya angiopathy (MMA) is a peculiar cerebrovascular condition characterized by progressive steno-occlusion of the terminal part of the internal carotid arteries (ICAs) and their proximal branches, associated with the development of a network of fragile collateral vessels at the base of the brain. The diagnosis is essentially made by radiological angiographic techniques. MMA is often idiopathic (moyamoya disease-MMD); conversely, it can be associated with acquired or hereditary conditions
more » ... yamoya Syndrome-MMS); however, the pathophysiology underlying either MMD or MMS has not been fully elucidated to date, and this poor knowledge reflects uncertainties and heterogeneity in patient management. MMD and MMS also have similar clinical expressions, including, above all, ischemic and hemorrhagic strokes, then headaches, seizures, cognitive impairment, and movement disorders. The available treatment strategies are currently shared between idiopathic MMD and MMS, including pharmacological and surgical stroke prevention treatments and symptomatic drugs. No pharmacological treatment able to reverse the progressive disappearance of the ICAs has been found to date in both idiopathic and syndromic cases. Antithrombotic agents are usually prescribed in ischemic MMA, although the coexisting hemorrhagic risk should be considered. Surgical revascularization techniques, which are currently the best available treatment in symptomatic MMA, are associated with good long-term outcomes and reduced ischemic and hemorrhagic risks. Given the lack of dedicated randomized clinical trials, current treatment is mainly based on observational studies and physicians' and surgeons' expertise.
doi:10.3390/jcm10163628 pmid:34441923 pmcid:PMC8397113 fatcat:vfhqaipsuzf7lg7ec3nhdptzty

Characterisation of biotinylated liposomes for in vivo targeting applications

Helen C. Loughrey, Anita Ferraretto, Ann-Marie Cannon, Giulia Acerbis, Francesco Sudati, Giovanni Bottiroli, Massimo Masserini, Marco R. Soria
1993 FEBS Letters  
Liposomes containing monosialoganglioside (G") or polyethylene glycol (PEG) lipid derivatives have prolonged circulation in the blood. This favours liposome extravasation to tumour sites. In this report it is shown that inclusion of G", PEGS,-DPPB or PEGmxrDPPE in liposomes containing biotin-DPPE signiticantly diminished the ability of vesicles to bind to streptavidin in vitro. Steric inhibition due to the bulky head group of these lipids was least for biotin-DPPE liposomes contaming C&i.
more » ... bu~on studies in CZ6 t~o~-~a~ng mice showed that ~~~-~~sornes containing small amo~ts of biotin-DPPE have long circulation l&-times in the blood. Using fluorescent microscopic techniques, liposomes contaming both G" and biot~-DPPE were detected within ex~-vault spaces in tumours. In addition it was shown that biotin-DPPE in G&iposomes bound streptavidin in situ. These results suggest that G"-liposomes containing biotin-DPPE have potential use as diagnostic or therapeutic reagents in pre-targeting applications dependent on the high-a&&y interaction of biotiu with streptavidin.
doi:10.1016/0014-5793(93)80509-s pmid:8405439 fatcat:rdzv5unv6ffmfevmyfw7rqtpty

Application of an aviation model of incident reporting and investigation to the neurosurgical scenario: method and preliminary data

Paolo Ferroli, Dario Caldiroli, Francesco Acerbi, Maurizio Scholtze, Alfonso Piro, Marco Schiariti, Eleonora F. Orena, Melina Castiglione, Morgan Broggi, Alessandro Perin, Francesco DiMeco
2012 Neurosurgical Focus  
Drafting the article: Ferroli, Acerbi, Scholtze, Piro. Critically revising the article: Ferroli, Schiariti. Reviewed submitted version of manuscript: all authors. Study supervision: DiMeco.  ... 
doi:10.3171/2012.9.focus12252 pmid:23116102 fatcat:ymyc5cbfazhzlnun45bvuococi

Fluorescence-Guided Surgery: A Review on Timing and Use in Brain Tumor Surgery

Alexander J. Schupper, Manasa Rao, Nicki Mohammadi, Rebecca Baron, John Y. K. Lee, Francesco Acerbi, Constantinos G. Hadjipanayis
2021 Frontiers in Neurology  
Acerbi et al. found fluorescence in 82% of tumors, including ependymomas, hemangioblastomas, astrocytoma, and a glioneuronal tumor forming rosettes (119) .  ...  To date, there are no randomized controlled trials for fluoresceinguided tumor surgery, however, in a recent multicenter phase II study, Acerbi et al. found that fluorescein was safe and effective in HGG  ...  Copyright © 2021 Schupper, Rao, Mohammadi, Baron, Lee, Acerbi and Hadjipanayis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).  ... 
doi:10.3389/fneur.2021.682151 fatcat:5txlrodn2zcqvdyeceutn2hbu4

Trigeminal interfascicular neurolysis (nerve combing) for refractory recurrent neuralgia in multiple sclerosis

Paolo Ferroli, Ignazio G. Vetrano, Francesco Acerbi, Gabriella Raccuia, Marco Schiariti, Paolo Confalonieri, Luisa Chiapparini, Morgan Broggi
2020 Neurosurgical Focus: Video  
In multiple sclerosis (MS) patients, trigeminal neuralgia (TN) represents a challenging syndrome to treat, often refractory to medical therapy and percutaneous techniques. Despite the frequent lack of a neurovascular conflict, the trigeminal nerve's axons are often damaged, with the myelin sheath permanently degenerated, thus explaining the difficulty in treating TN in MS.The authors illustrate trigeminal interfascicular neurolysis (the combing technique) to control refractory recurrent TN in
more » ... : the nerve is longitudinally divided along its fibers from the root entry zone, determining good pain relief.The video can be found here: https://youtu.be/o1XksPW5fMY
doi:10.3171/2020.5.focvid203 fatcat:dy4rscyrtvggtjx22tm4axao7m

The effect of ozone injection within a common peroneal nerve schwannoma: A mistreatment due to a misdiagnosis

Ignazio Gaspare Vetrano, Francesco Acerbi, Gianluca Marucci, Vittoria Nazzi
2020 Surgical neurology international  
Peripheral schwannomas can be misdiagnosed or mistreated as they can mimic other subcutaneous lesions, leading to wrong diagnosis and, therefore, to improper treatment. Case Description: A 23-years-old male presented a painful growing nodule at the left popliteal fossa, with distally irradiated pain. A first magnetic resonance imaging depicted a heterogeneous lesion between common peroneal and sural nerves but, surprisingly, the patient was submitted to perilesional injection of ozone-oxygen
more » ... ture, causing the onset of intense neuropathic pain. A second MRI showed a morphological change of tumor characteristics. He finally underwent surgery but, intraoperatively, inter-fascicular fibrous adherences were noticed, making the tumor removal more difficult and riskier. The histopathological diagnosis was of schwannoma with areas of foreign body reaction. Conclusion: The injection of ozone or other substances within a subcutaneous swelling should be avoided, before a complete imaging assessment; because of such swelling could be a peripheral nerve schwannoma. The correct assessment of a lesion of the limbs determining radiating pain should be carefully demanded to a thorough history, clinical examination, and appropriate imaging technique. To avoid incorrect management, the treatment of such tumors should be performed in the first place by dedicated equips with proven expertise in this field.
doi:10.25259/sni_296_2020 pmid:33365176 pmcid:PMC7749957 fatcat:nnsmeok5brbuhkwmz4xbpf6hau
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