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The effects of acute alcohol administration on the human brain: Insights from neuroimaging

James M. Bjork, Jodi M. Gilman
2014 Neuropharmacology  
These in vivo neuroimaging studies generally show that acute alcohol administration affects brain structures implicated in motivation and behavior control, and that chronic intoxication is correlated with  ...  We then briefly address how chronic alcohol intoxication (as inferred from cross-sectional differences between various drinking populations and controls) may yield individual brain differences between  ...  Cited original research performed by the authors was funded by intramural funding of the National Institute on Alcohol Abuse and Alcoholism.  ... 
doi:10.1016/j.neuropharm.2013.07.039 pmid:23978384 pmcid:PMC3971012 fatcat:ibcxzzx6ijgzfbs4dmgoflpmeq

Brain proton magnetic resonance spectroscopy of alcohol use disorders [chapter]

Dieter J. Meyerhoff
2014 Handbook of Clinical Neurology  
NAA in female and male alcoholics.  ...  Nevertheless, stopping alcohol intake is not the panacea for optimal brain health.  ... 
doi:10.1016/b978-0-444-62619-6.00019-7 pmid:25307583 pmcid:PMC4876042 fatcat:bo62673a2fcqbl5m37ng4ge47e

Interactive effects of chronic cigarette smoking and age on hippocampal volumes

Timothy C. Durazzo, Dieter J. Meyerhoff, Sara Jo Nixon
2013 Drug and Alcohol Dependence  
NAA in female and male alcoholics.  ...  Nevertheless, stopping alcohol intake is not the panacea for optimal brain health.  ... 
doi:10.1016/j.drugalcdep.2013.08.020 pmid:24051060 pmcid:PMC3870586 fatcat:y6fwbeop2ra2vp3qmheb3iulru

Chronic alcoholism: Insights from neurophysiology

S. Campanella, G. Petit, P. Maurage, C. Kornreich, P. Verbanck, X. Noël
2009 Neurophysiologie clinique  
deficits at the level of the sensory cortex and not only disturbances involving associative cortices and limbic structures; and (4) decreased theta, gamma and delta oscillations, suggesting cognitive  ...  "inhibitory" cortical dysfunction; (3) decreased amplitude for cognitive event-related potentials situated along the continuum of informationprocessing, suggesting that alcoholism is associated with neurophysiological  ...  Although not as significant as in males, recent studies have indicated that smaller P3 amplitudes are also present in female alcoholics [158] .  ... 
doi:10.1016/j.neucli.2009.08.002 pmid:19853791 fatcat:5qobpxgc4jhuvmf6jgxi2sgzny

Moderate Mocha Coffee Consumption Is Associated with Higher Cognitive and Mood Status in a Non-Demented Elderly Population with Subcortical Ischemic Vascular Disease

Francesco Fisicaro, Giuseppe Lanza, Manuela Pennisi, Carla Vagli, Mariagiovanna Cantone, Giovanni Pennisi, Raffaele Ferri, Rita Bella
2021 Nutrients  
We assessed the association between different quantities of mocha coffee intake over the last year and cognitive and mood performance in a homogeneous sample of 300 non-demented elderly Italian subjects  ...  Daily mocha coffee intake was associated with higher cognitive and mood status, with a significant dose-response association even with moderate consumption.  ...  and occasional drinkers, whereas the incidence of WMLs was lower in female drinkers than female non-drinkers or occasional drinkers.  ... 
doi:10.3390/nu13020536 pmid:33562065 pmcid:PMC7916014 fatcat:a2xeemtbmbfezg3tocpbqrlnam

ETHANOL AND NMDA RECEPTOR COUPLING TO ERK SIGNALING

Lawrence J. Chandler
2004 Alcoholism: Clinical and Experimental Research  
drinking, but not that due to deprivation alone.  ...  The excitatory actions of GABA generate these GDPs, which are associated with large oscillations in intracellular calcium.  ...  Alcoholics (male and female) have significantly smaller ICV than healthy non-alcoholics.  ... 
doi:10.1097/00000374-200408002-00418 fatcat:gyt6k6qtbveibppgmo6225nzf4

Speaker Abstracts

2021 Alcoholism: Clinical and Experimental Research  
Previous studies have identified transcriptomic patterns in the brain associated with alcohol dependence in both humans and animal models.  ...  Multiomics approaches used to delineate cell type-specific differences in brain function could greatly advance knowledge molecular mechanisms associated with alcohol-dependent individuals.  ...  Caspase-mediated ablation of these CeA-NTS neurons reduced voluntary ethanol intake and preference in male, but not female mice.  ... 
doi:10.1111/acer.14617 fatcat:htkr7pxcz5allmlpcwojtu6dyu

Structural and Functional Imaging Studies in Chronic Cannabis Users: A Systematic Review of Adolescent and Adult Findings

Albert Batalla, Sagnik Bhattacharyya, Murat Yücel, Paolo Fusar-Poli, Jose Alexandre Crippa, Santiago Nogué, Marta Torrens, Jesús Pujol, Magí Farré, Rocio Martin-Santos, Lin Lu
2013 PLoS ONE  
Functional neuroimaging studies suggest different patterns of resting global and brain activity during the performance of several cognitive tasks both in adolescents and adults, which may indicate compensatory  ...  Conclusion: Chronic cannabis use may alter brain structure and function in adult and adolescent population.  ...  McQueeny et al. (2011) [156] also described an effect of gender in which female cannabis users but not males, exhibited a larger right amygdala volume.  ... 
doi:10.1371/journal.pone.0055821 pmid:23390554 pmcid:PMC3563634 fatcat:pffvgfex3navzibcbmsgltjcfu

1301 – Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings

A. Batalla, S. Bhattachayyria, M. Yucel, P. Fusar-Poli, J.A. Crippa, S. Nogué, M. Torrens, J. Pujol, M. Farré, R. Martín-Santos
2013 European psychiatry  
Functional neuroimaging studies suggest different patterns of resting global and brain activity during the performance of several cognitive tasks both in adolescents and adults, which may indicate compensatory  ...  Conclusion: Chronic cannabis use may alter brain structure and function in adult and adolescent population.  ...  McQueeny et al. (2011) [156] also described an effect of gender in which female cannabis users but not males, exhibited a larger right amygdala volume.  ... 
doi:10.1016/s0924-9338(13)76359-4 fatcat:q63hx57xf5hnvkgllvla5iyafe

ESBRA 2005 SYMPOSIA ABSTRACTS

2005 Alcohol and Alcoholism  
While most epidemiological studies also show a positive association for alcohol consumption, this association may not be dose dependent.  ...  Several studies have pointed out the role of cigarette smoking and alcohol consumption in GERD, with a dose-dependent increase of odds ratios, especially for smoking.  ...  Acknowledgement Work in the author's laboratory is sponsored by the Royal Society, UK. Acknowledgement Funded by UK NHS Research and Development.  ... 
doi:10.1093/alcalc/agh208 fatcat:m2w7mzwm4ngutifjpzgy4i2ivq

Pattern of Motor and Cognitive Deficits in Detoxified Alcoholic Men

E. V. Sullivan, M. J. Rosenbloom, A. Pfefferbaum
2000 Alcoholism: Clinical and Experimental Research  
superior vermis but no association between lifetime alcohol consumption and ver- mian volumes.  ...  Nixon SJ, Tivis R, Parsons OA (1995) Behavioral dysfunction and cogni- tive efficiency in male and female alcoholics. Alcohol Clin Exp Res 19:577-581.  ... 
doi:10.1111/j.1530-0277.2000.tb02032.x pmid:10832902 fatcat:gqtkq6ek7jchjbasgifx5uqwle

Poster Session III-Wednesday

2013 Neuropsychopharmacology  
In contrast, genes associated with neurodegenerative diseases exhibit strong gender differences, assembling to form an additional module in late life in the male samples but not in the female samples.  ...  However, the relationship between ACEs and alcohol seeking behavior in non-dependent drinkers is less clear.  ...  In males, a high fat diet led to greater sensitivity to cocaine reward in males, but not in females.  ... 
doi:10.1038/npp.2013.281 fatcat:n2o3tllrsrbyxgzsfwzhl5psua

MEDICAL CONSEQUENCES OF SUBSTANCE ABUSE

Michael D. Stein
1999 Psychiatric Clinics of North America  
The association between alcohol abuse and high-risk behaviors for acquiring AIDS has more recently been demonstrated by the finding of a substantial prevalence of HIV infection among clients of alcohol-addiction  ...  The first discusses the complications of alcohol, the most commonly abused substance in the United States.  ...  [6] Alcoholic cardiac myopathy that is diagnosed early responds to the cessation of alcohol intake. Cardiomyopathy and myopathy 355 are more common in female alcoholics than in male alcoholics.  ... 
doi:10.1016/s0193-953x(05)70081-2 pmid:10385938 fatcat:g7ny5iybmzdmbmdzi5t4maxc4m

Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder

N. W. Gilpin, J. L. Weiner
2016 Genes, Brain and Behavior  
In a study of alcohol-dependent men with comorbid PTSD, a history of emotional abuse in childhood was found to contribute to impaired quality of life (Evren et al. 2011) .  ...  Are there other risk factors associated with this dual diagnosis?  ...  Acknowledgments This work was supported by NIH grants AA023305 (N.W.G.) and AA017531, AA010422, AA121099 (J.L.W.).  ... 
doi:10.1111/gbb.12349 pmid:27749004 pmcid:PMC5477640 fatcat:tvjj5la47jamjk3xr26riuoizy

Cue-reactivity in the ventral striatum characterizes heavy cannabis use, whereas reactivity in the dorsal striatum mediates dependent use: Supplemental [article]

Xinqi Zhou, Kaeli Zimmermann, Fei Xin, Roelinka Derck, Anja Sassmannshausen, Dirk Scheele, Rene Hurlemann, Bernd Weber, Keith Kendrick, Benjamin Becker
2019 bioRxiv   pre-print
An exploratory analysis revealed that higher ventral caudate cue-reactivity was associated with stronger cue-induced arousal and craving in dependent users, whereas this pattern was reversed in non-dependent  ...  To differentiate the adaptive changes, the present functional magnetic resonance imaging study examined behavioral and neural cue-reactivity in dependent (n = 18) and non-dependent (n = 20) heavy cannabis  ...  Acknowledgements We thank the authors of previous cannabis cue-reactivity studies (30, 68) for providing the cannabis-associated stimuli. The authors declare no competing interests.  ... 
doi:10.1101/516385 fatcat:gikpruru5fhkjlt2xetcr7vccm
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