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Fluid-Structure Interaction Modelling of Left Ventricular Filling [chapter]

Pascal R. Verdonck, Jan A. Vierendeels
2002 Lecture Notes in Computer Science  
A computer model is developed describing three-dimensional axi-symmetrical LV filling flow.  ...  Non-invasive assessment of the flow field within the left ventricle (LV) using color M-mode Doppler (CMD) echocardiography provides a potential technique that can differentiate between the normal and diseased  ...  Acknowledgements The research reported here was granted by contract GOA-95003 of the concerted action programme of the Ghent university, supported by the Flemish government.  ... 
doi:10.1007/3-540-47789-6_29 fatcat:ayivfkfv4fe5pniihnlwtipm5i

Simulation of left ventricle flow dynamics with dilated cardiomyopathy during the filling phase

B. T. Chan, C. W. Ong, E. Lim, N. A. Abu Osman, A. Al Abed, N. H. Lovell, S. Dokos
2012 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society  
and the fluid structure interaction (FSI) methods.  ...  Results showed that vortex strength and IVPGs are significantly reduced in a dilated heart, leading to an increased risk of thrombus formation and impaired ventricular filling.  ...  [10] developed an axisymmetric fluid dynamics model of the left ventricle, coupled to a lumped parameter model of the complete circulation, to investigate the influence of a ventricular assist device  ... 
doi:10.1109/embc.2012.6347432 pmid:23367367 dblp:conf/embc/ChanOLOALD12 fatcat:xqhjhnsqorgplgjxynmlwth55u

Optimization of Left Ventricle Pace Maker Location Using Echo-Based Fluid-Structure Interaction Models

Longling Fan, Jing Yao, Liang Wang, Di Xu, Dalin Tang
2022 Frontiers in Physiology  
Echo-based left ventricle fluid-structure interaction models were constructed to perform ventricle function analysis and investigate impact of pacemaker location on cardiac outcome.  ...  model) and right ventricular outflow tract (RVOT model).  ...  The Fluid-Structure Interaction Model of Left Ventricular Blood flow in the left ventricle was assumed to be laminar, Newtonian, viscous and incompressible.  ... 
doi:10.3389/fphys.2022.843421 pmid:35250642 pmcid:PMC8892190 fatcat:jiwzamn7brezhcuj2qxdzwcx6e

Fluid-Structure Interaction Model of Human Mitral Valve within Left Ventricle [chapter]

Hao Gao, Nan Qi, Xingshuang Ma, Boyce E. Griffith, Colin Berry, Xiaoyu Luo
2015 Lecture Notes in Computer Science  
The model is derived from clinical images and takes into account of the important valvular features, left ventricle contraction, nonlinear soft tissue mechanics, fluid structure interaction, and the MV-LV  ...  Although the model is a step closer towards simulating physiological realistic situation, further work is required to ensure that the highly complex valvular-ventricular interaction, and the fluid-structure  ...  B.E.G. acknowledges research support from the American Heart Association (AHA award 10 SDG4320049), the National Institutes of Health (award HL117063), and the National Science Foundation (awards DMS 1016554  ... 
doi:10.1007/978-3-319-20309-6_38 fatcat:y2ngpwea3jfyvffwkh4gyabumi

Mitral valve dynamics in structural and fluid–structure interaction models

K.D. Lau, V. Diaz, P. Scambler, G. Burriesci
2010 Medical Engineering and Physics  
Comparison of the fluid domains of the fluid-structure interaction models have shown that the ventricular geometry generates slower fluid velocity with increased vorticity compared to the tubular geometry  ...  Using fluid-structure interaction, the valve has been modelled separately in a straight tubular volume and in a U-shaped ventricular volume, in order to analyse the difference in the coupled fluid and  ...  Lau would like to acknowledge and thank Constantinos Zervides for providing the orginal ANSYS to LS-DYNA conversion script and the support of the British Heart Foundation, the ESPRC and the MRC.  ... 
doi:10.1016/j.medengphy.2010.07.008 pmid:20702128 pmcid:PMC2989441 fatcat:cppccltkfneuplohg4ghyymogy

Fluid Structure Interaction Simulation of Left Ventricular Flow Dynamics under Left Ventricular Assist Device Support

C. W. Ong, B. T. Chan, E. Lim, N. A. Abu Osman, A. A. Abed, S. Dokos, N. H. Lovell
2012 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society  
In this paper, we present a 2D axisymmetric fluid structure interaction model of the passive left ventricle (LV) incorporating an LVAD cannula to simulate the effect of the LVAD cannula placement on the  ...  For patient's receiving mechanical circulatory support, malfunction of the left ventricular assist device (LVADs) as well as mal-positioning of the cannula imposes serious threats to their life.  ...  A 1 cm tube with a diameter Fluid Structure Interaction Simulation of Left Ventricular Flow Dynamics under Left Ventricular Assist Device Support ) 1 ( 2 1 ) 3 ( ) 3 (       el s J k I C I C W  ... 
doi:10.1109/embc.2012.6347433 pmid:23367368 dblp:conf/embc/OngCLOADL12 fatcat:aoyefo74qvgmrj6gwwe6lbiytq

Multiphysics Simulation of Left Ventricular Filling Dynamics Using Fluid-Structure Interaction Finite Element Method

Hiroshi Watanabe, Seiryo Sugiura, Hidenobu Kafuku, Toshiaki Hisada
2004 Biophysical Journal  
coupling and its propagation, and simulated the fluid-structure interaction involved in the contraction and relaxation of the human left ventricle.  ...  Furthermore, fluid-structure analysis enabled us to analyze the wave propagation velocity of filling flow.  ...  Study limitation Toward the complete modeling of the left ventricular filling, there are still many aspects to be added to the current model.  ... 
doi:10.1529/biophysj.103.035840 pmid:15345582 pmcid:PMC1304609 fatcat:5bmw3ywvbvcybmmdd74qhcgj5a

Fluid Flow inside Deformable Vessels and in the Left Ventricle [chapter]

Gianni Pedrizzetti, Federico Domenichini
2003 Cardiovascular Fluid Mechanics  
The formulation of the flow in a model left ventricle is given, and numerical solutions for flow during the left ventricle filling (diastole) is studied and analysed in terms of vorticity dynamics.  ...  The theory of finite elasticity is summarised in a perspective of application to fluid-tissue interaction problems. The formulation of a coupled fluid tissue problem is discussed.  ...  The Influence of the Mitral Valve on the Fluid Dynamics of the Left Ventricular Filling Introduction The principal fluid phenomena involved in the left ventricular flow during the diastolic phase are  ... 
doi:10.1007/978-3-7091-2542-7_4 fatcat:aw3whxs3pnbgvokwrjpn4io4pi

Simulation of the dynamic flow field in the left ventricle of the heart during diastolic filling

Jianhua Adu, Lixue Yin, Hongmei Zhang, Shenghua Xie, Jing Lu
2020 AIP Advances  
ARTICLE Simulation of the dynamic flow field in the left ventricle of the heart during diastolic filling ABSTRACT Fluid-structure interaction (FSI) problems in modeling flexible  ...  Finally, we verify the effectiveness of the coupled models by simulating the effects of diastolic jet flow on the motion of the mitral leaflets in the simplified left ventricular flow model.  ...  FIG. 3 . 3 Model structure of the left ventricular flow field.  ... 
doi:10.1063/1.5126470 fatcat:va4ef4bolbbsjb7ktatjmj6qiu

Vortex formation and instability in the left ventricle

Trung Bao Le, Fotis Sotiropoulos, Dane Coffey, Daniel Keefe
2012 Physics of Fluids  
In the fluid dynamics videos, we describe in detail the three-dimensional structure of the mitral vortex ring, which is formed during early diastolic filling.  ...  The left ventricular kinematics is modeled via a cell-based activation methodology, which is inspired by cardiac electro-physiology and yields physiologic LV wall motion.  ...  left ventricular wall during late diastolic filling.  ... 
doi:10.1063/1.4747164 pmid:23112565 pmcid:PMC3465351 fatcat:kdlorrlnyrdl3kw3jsqsjt2rgy

Computational modeling and analysis of intracardiac flows in simple models of the left ventricle

X. Zheng, J.H. Seo, V. Vedula, T. Abraham, R. Mittal
2012 European journal of mechanics. B, Fluids  
The left-ventricle is modeled as a semi-prolate-spheroid, and the wall motion is driven by a prescribed ventricular volume-change that consists of five stages: early (E) filling, diastasis, atrial (A)  ...  Computational modeling is used to study intracardiac flows in normal and diseased left-ventricles.  ...  Computational resources for some of the simulations were also provided in part through the NSF grant NSF-OCI-108849.  ... 
doi:10.1016/j.euromechflu.2012.03.002 fatcat:aad6vmghizfhdfpdhutknpv4oi

Synergy between Diastolic Mitral Valve Function and Left Ventricular Flow Aids in Valve Closure and Blood Transport during Systole

Vijay Govindarajan, John Mousel, H. S. Udaykumar, Sarah C. Vigmostad, David D. McPherson, Hyunggun Kim, Krishnan B. Chandran
2018 Scientific Reports  
of mitral valve (MV) function and left ventricular (LV) fluid dynamics.  ...  The overall optimal performance of the LV depends in part on ventricular filling during diastole 2 .  ...  Sciences which is funded by National Institutes of Health Clinical and Translational Award (UL1TR000371), and by support from the endowed professorship of Dr.  ... 
doi:10.1038/s41598-018-24469-x pmid:29670148 pmcid:PMC5906696 fatcat:nuossuaik5e2hl7zt4yuisngxi

The looped heart does not save energy by maintaining the momentum of blood flowing in the ventricle

Hiroshi Watanabe, Seiryo Sugiura, Toshiaki Hisada
2008 American Journal of Physiology. Heart and Circulatory Physiology  
However, at high heart rates, such complete clearance was observed only in the physiological model, whereas 27.0% of blood remained in the nonphysiological model.  ...  The work performed by the ventricular wall was comparable at slower and faster heart rates (physiological vs. nonphysiological, 0.864 vs. 0.874 J, heart rate ϭ 60 beats/min; and 0.599 vs. 0.590 J, heart  ...  The blood in the ventricle (fluid part) was also modeled by FEM with 18,976 elements, and its interaction with the ventricular wall (structure part) was analyzed by the fluid-structure interaction FEM,  ... 
doi:10.1152/ajpheart.00041.2008 pmid:18326797 fatcat:5ao3rxjpljgc7fwm6vxto2kqru

Computer and Experimental Modelling of Blood Flow through the Mitral Valve of the Heart

Mushtak AL-ATABI, Daniel M. ESPINO, David W. L. HUKINS
2010 Journal of Biomechanical Science and Engineering  
In this paper, blood flow in idealised two-dimensional models of the mitral valve was studied using a numerical fluid-structure interaction (FSI) and experimental models and an experimental problem designed  ...  This paper reports the first steps in determining the effects of fluid flow on the performance of the mitral valve of the heart that is relevant to surgical repair of the valve.  ...  These Fluid-Structure Interaction (FSI) models of the mitral valve have simulated the flow of blood through the valve in a conduit and generally ignored the effect of the left ventricle of the heart on  ... 
doi:10.1299/jbse.5.78 fatcat:utvfwhc27vd7zl2rcrahonrdvy

A Multiphysics Biventricular Cardiac Model: Simulations With a Left-Ventricular Assist Device

Azam Ahmad Bakir, Amr Al Abed, Michael C. Stevens, Nigel H. Lovell, Socrates Dokos
2018 Frontiers in Physiology  
To investigate the performance of a left-ventricular assist device (LVAD), a fully-coupled cardiac fluid-electromechanics finite element model was developed, incorporating electrical activation, passive  ...  To investigate heart-LVAD interaction, we reduced the left ventricular (LV) contraction stress to mimic a failing heart, and inserted a LVAD cannula at the LV apex with continuous flow governing the outflow  ...  ACKNOWLEDGMENTS This research was undertaken with the assistance of resources and services from the National Computational Infrastructure (NCI), which is supported by the Australian Government.  ... 
doi:10.3389/fphys.2018.01259 pmid:30271353 pmcid:PMC6142745 fatcat:pptcqh5lovcepetwwby7c35rqa
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