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Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI

Justin Lo, Adam Lim, Matthias W Wagner, Birgit Ertl-Wagner, Dafna Sussman
identify anomalies in fetal organs.  ...  This work aims to develop a novel classification architecture identifying the affected organs in fetal MRI.  ...  The authors would also like to acknowledge Susan Blaser for being instrumental in establishing fetal MRI at the Hospital for Sick Children in Toronto, from which the de-identified images were acquired.  ... 
doi:10.3389/frai.2022.832485 pmid:35372832 pmcid:PMC8972161 fatcat:wdf3upsuwneo3bm3v5ppcvutji

Congenital brain anomalies and chromosomal aberrations from the Zagreb Collection of human brains

Božo Krušlin, Tihana Džombeta, Miran Bezjak, Goran Sedmak, Zdravko Petanjek, Goran Šimić, Miloš Judaš, Ivica Kostović
2014 Translational Neuroscience  
The Zagreb Collection, however, also contains approximately 100 brains with different anomalies including chromosomal aberrations such as Down syndrome.  ...  Previous studies on this material have led to several important contributions on human cortical development, such as the discovery of the transient fetal subplate zone.  ...  Etiology and pathogenesis of central nervous system (CNS) anomalies, as well as anomalies of other organ systems, are still relatively unknown (40-60%).  ... 
doi:10.2478/s13380-014-0231-9 fatcat:z5x47ic5nfadng2ynvw7bziike

Ultrasound Medical Images Classification Based on Deep Learning Algorithms: A Review

Fairoz Q. Kareem, Adnan Mohsin Abdulazeez
2021 Zenodo  
In this paper we reviewed what have researchers have done in their researches to solve fetal problems, then summarize and carefully discuss the applications in different tasks identified for segmentation  ...  and classification of ultrasound images.  ...  To identify markers for a more accurate prognosis, the resultant segmentations are used in the cortical folding of INSVM fetuses to identify anomalies.  ... 
doi:10.5281/zenodo.4621288 fatcat:vzff53p4enfvlonl6kvnsqxqre

Application of artificial intelligence in obstetrics

Ho Yeon Kim, Geum Joon Cho, Han-Sung Kwon
2022 Ultrasonography  
This review provides an overview of artificial intelligence systems currently used for obstetric diagnostic utilities such as fetal cardiotocography, ultrasonography and magnetic resonance imaging and  ...  It analyzes large amount of data to assist in disease prediction, prevention, diagnosis and monitoring patients.  ...  For video and image processing, convolutional neural network(CNNs) has been applied in deep learning and it contains deeper networks with more convolutional layers and has ability to put information more  ... 
doi:10.14366/usg.22063 fatcat:m5iekfu3sfbydiw7oqorviszse


2012 Fetal and maternal medicine review  
In cases of brain anomalies, referral for MRI imaging may be appropriate.  ...  at which fetal anomalies are detected on scan and increasing severity of the abnormalities identified.  ... 
doi:10.1017/s0965539512000034 fatcat:bmprkgurrjf7hcfiucg43ucgnu

"The First Thousand Days" Define a Fetal/Neonatal Neurology Program

Mark S. Scher
2021 Frontiers in Pediatrics  
Destructive fetal brain lesions later in pregnancy result from ischemic placental syndromes associated with the great obstetrical syndromes.  ...  A fetal/neonatal program (FNNP) applying this perspective better identifies trimester-specific mechanisms affecting the maternal/placental/fetal (MPF) triad, expressed as brain malformations and destructive  ...  Earlier imaging abnormalities utilizing sonography generally require later confirmation by fetal or neonatal MRI studies with greater potential to detect anomalies.  ... 
doi:10.3389/fped.2021.683138 fatcat:kad2mtok7zeatea3i2bbzngn24

Genome sequencing combining prenatal ultrasound in the evaluation of fetal CNS structural anomalies [article]

Ying Yang, Sheng Zhao, Guoqiang Sun, Fang Chen, Tongda Zhang, Jieping Song, Wenzhong Yang, Lin Wang, Nianji Zhan, Xiaohong Yang, Xia Zhu, Bin Rao (+11 others)
2020 medRxiv   pre-print
Purpose: Genome sequencing (GS) is potentially the most suitable diagnostic tools for fetal CNS structural anomalies.  ...  However, its efficacy hasn't been proved in large cohort of fetal CNS structural anomalies.  ...  Ultrasonography is the most important modality for evaluation of fetal growth and anatomy with high efficiency and specificity of detecting congenital anomalies prenatally, especially in CNS. 2 Fetal MRI  ... 
doi:10.1101/2020.03.04.20031294 fatcat:egbzlwupdbaqjfc4w2mbcshmim

Prenatal maternal biomarkers for the early diagnosis of congenital malformations: A review

Richard Wagner, Wai Hei Tse, Jan-Hendrik Gosemann, Martin Lacher, Richard Keijzer
2019 Pediatric Research  
Because accurate and robust laboratory tests are unavailable for most birth defects, physicians rely on imaging such as ultrasound and MRI.  ...  Recent large-scale analysis ('omics') have enabled researchers to identify novel biomarkers in different areas.  ...  ACKNOWLEDGEMENTS We thank Clara Moy Tam for her help with the figures. R.K. holds the Thorlakson Chair in Surgical Research that supported this work.  ... 
doi:10.1038/s41390-019-0429-1 pmid:31091529 fatcat:n3p4anasvjcs3lii324balvipm

Epidemiology of congenital cerebral anomalies in Europe: a multicentre, population-based EUROCAT study

Joan K Morris, Diana G Wellesley, Ingeborg Barisic, Marie-Claude Addor, Jorieke E H Bergman, Paula Braz, Clara Cavero-Carbonell, Elizabeth S Draper, Miriam Gatt, Martin Haeusler, Kari Klungsoyr, Jennifer J Kurinczuk (+19 others)
2019 Archives of Disease in Childhood  
ObjectivesTo describe the epidemiology and geographical differences in prevalence of congenital cerebral anomalies in Europe.Design and settingCongenital cerebral anomalies (International Classification  ...  non-cerebral anomalies, prenatal detection rate.Results4927 cases with congenital cerebral anomalies were identified; a prevalence (adjusted for under-reporting) of 9.8 (95% CI: 8.5 to 11.2) per 10 000  ...  Acknowledgements We thank JRC-EUROCAT Central Registry, European Commission, Joint Research Centre (JRC), Ispra, Italy, for the data management and selection of cases included in the study.  ... 
doi:10.1136/archdischild-2018-316733 pmid:31243007 fatcat:gcb5hodazrgjznqvhp2rbi5p3q

A maChine and deep Learning Approach to predict pulmoNary hyperteNsIon in newbornS with congenital diaphragmatic Hernia (CLANNISH): Protocol for a retrospective study

Ilaria Amodeo, Giorgio De Nunzio, Genny Raffaeli, Irene Borzani, Alice Griggio, Luana Conte, Francesco Macchini, Valentina Condò, Nicola Persico, Isabella Fabietti, Stefano Ghirardello, Maria Pierro (+7 others)
2021 PLoS ONE  
A software system for automatic fetal lung volume segmentation in MRI based on the DL 3D U-NET approach will also be developed.  ...  The native sequences from fetal magnetic resonance imaging (MRI) will be collected.  ...  The network will be trained and optimized for fetal lung volume segmentation in MRI. To cope with the small sample size issue, we plan to implement data augmentation techniques [84] .  ... 
doi:10.1371/journal.pone.0259724 pmid:34752491 pmcid:PMC8577746 fatcat:jeidt5mt6rgcrhz7bs2notii6y

Clinical presentation, diagnosis, and management of fetal alcohol spectrum disorder

Jeffrey R Wozniak, Edward P Riley, Michael E Charness
2019 Lancet Neurology  
Global prevalence of fetal alcohol spectrum disorder is 0·77%, with a higher prevalence of 2-5% in Europe and North America, highlighting the need for increased diagnosis and treatment.  ...  Although prenatal alcohol exposure causes craniofacial anomalies, growth retardation, neurological abnormalities, cognitive impairment, and birth defects, fetal alcohol spectrum disorder is underdiagnosed  ...  Magnetic Resonance Imaging (MRI) of 12-year old males with fetal alcohol syndrome (FAS) and with typical development.  ... 
doi:10.1016/s1474-4422(19)30150-4 pmid:31160204 pmcid:PMC6995665 fatcat:6ufzxsuwi5ashkyy7axwftblm4

Front Matter: Volume 11597

Karen Drukker, Maciej A. Mazurowski
2021 Medical Imaging 2021: Computer-Aided Diagnosis  
- organ auto-delineation [11597-44] 11597 1C Multiview and multiclass image segmentation using deep learning in fetal echocardiography [11597-45] v Proc. of SPIE Vol. 11597 1159701-5 Multi-scale  ...  view-based convolutional neural network for breast cancer classification in ultrasound images [11597-46] NEURORADIOLOGY INCLUDING HEAD AND NECK 11597 1E Differentiation of Parkinson's disease and  ...  detection in volumetric laser endomicroscopy using bi-directional gated recurrent neural networks 11597 2J Automatic segmentation of the structures in the nasal cavity and the ethmoidal sinus for the  ... 
doi:10.1117/12.2595447 fatcat:u25cvo7adbgcxb363rsnsgnsju

Prenatal regenerative fetoscopic interventions for congenital anomalies

Rodrigo Ruano
2020 The BMJ (British Medical Journal)  
Fetal intervention has progressed in the past two decades from experimental proof-of-concept to practice-adopted, life saving interventions in human fetuses with congenital anomalies.  ...  By altering the natural course of disease through regrowth or redevelopment of malformed fetal organs, prenatal regenerative medicine has transformed maternal-fetal care.  ...  , and capillary network are formed.  ... 
doi:10.1136/bmj.m1624 pmid:32611543 fatcat:y7f5mc26frhp5g5ktaa5kpomgm

Fetal Brain Development: Regulating Processes and Related Malformations

Zvi Leibovitz, Tally Lerman-Sagie, Leila Haddad
2022 Life  
Fetal ventriculomegaly, which frequently accompanies these disorders, is also reviewed.  ...  The processes are described according to the developmental timetable: dorsal induction, ventral induction, neurogenesis, neuronal migration, post-migration neuronal development, and cortical organization  ...  Fetal brain MRI is an important contributing tool for fetal VM assessment, providing additive information in 1-14% of cases (primarily related to MCD, callosal, and vermian anomalies) [127] .  ... 
doi:10.3390/life12060809 pmid:35743840 pmcid:PMC9224903 fatcat:5z6ty2o2iffhvjgjvhovqp74r4

Congenital diaphragmatic hernia: 25 years of shared knowledge; what about survival?

Lakshminrusimha Satyan, Vali Payam
2019 Jornal de Pediatria  
Herniation of the abdominal organs through a malformed and defective diaphragm during fetal development can lead to nearlethal pulmonary hypoplasia and cardiac deformation.  ...  Congenital diaphragmatic hernia (CDH) remains one of the most dreaded congenital anomalies in the neonatal intensive care units (NICUs).  ...  If a prenatal diagnosis of CDH is confirmed, careful fetal evaluation by ultrasound, MRI, and fetal echocardiography can identify several prognostic predictors of newborn outcomes, which include herniation  ... 
doi:10.1016/j.jped.2019.10.002 pmid:31629706 pmcid:PMC7162701 fatcat:kg7lobs3bbantfhd3ywqy3fuby
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