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Bootstrapping Cookbooks for APIs from Crowd Knowledge on Stack Overflow [article]

Lucas B. L. Souza, Eduardo C. Campos, Fernanda Madeiral, Klérisson Paixão, Adriano M. Rocha, Marcelo de Almeida Maia
2019 arXiv   pre-print
(b) Chapter 2 from the SWT API Cookbook: SWT table component. Figure 1 : 1 A cookbook example: (a) cookbook summary, (b) recipes within a chapter, (c) a recipe.  ...  On recommendation systems using Stack Overflow content, Campos et al. [24] proposed a solution to recommend Q&A pairs to programming tasks that developers are facing.  ... 
arXiv:1903.09174v1 fatcat:rkrieqzw6vbttla5q2d4r7ckrm

Water sorption kinetics of damaged beans: GAB model

Fernanda M. Baptestini, Paulo C. Corrêa, Jaime D. B. Vanegas, Rafael Leite, Fernando M. Botelho, Renata C. Campos
2017 Revista Brasileira de Engenharia Agrícola e Ambiental - Agriambi  
To obtain the equilibrium moisture content, grains were placed in a climatic chamber at 20, 30, 40 and 50 ± 1 °C combined with relative humidity of 30, 40, 50, 70 and 90 ± 3%.  ...  C. B.  ...  Figure 3 . 3 Hysteresis at 20 °C: (A) control and (B) damaged beans B.  ... 
doi:10.1590/1807-1929/agriambi.v21n8p550-555 fatcat:cqusii7fcrhlfeb3lfcucplmym

Detection of Chikungunya virus in bodily fluids: The INOVACHIK cohort study

Ezequias B. Martins, Michele F. B. Silva, Wagner S. Tassinari, Fernanda de Bruycker-Nogueira, Isabella C. V. Moraes, Cintia D. S. Rodrigues, Carolina C. Santos, Simone A. Sampaio, Anielle Pina-Costa, Allison A. Fabri, Vinícius Guerra-Campos, Nayara A. Santos (+5 others)
2022 PLoS Neglected Tropical Diseases  
We defined fever as an axillary temperature � 37.5˚C. Patients with symptoms reported for up to 7 days were included in the study.  ... 
doi:10.1371/journal.pntd.0010242 pmid:35255099 pmcid:PMC8929700 fatcat:7kdcjctyfndoviwlvvs66sfggi

Non-invasive Transdermal Delivery of Human Insulin Using Ionic Liquids: In vitro Studies

Ludmilla R. Jorge, Liliam K. Harada, Erica C. Silva, Welida F. Campos, Fernanda C. Moreli, Gustavo Shimamoto, Jorge F. B. Pereira, José M. Oliveira, Matthieu Tubino, Marta M. D. C. Vila, Victor M. Balcão
2020 Frontiers in Pharmacology  
Besides, Figures 2ii-b ,c are two expansions to highlight the upfield shifts from 2.18 to 2.02 ppm, related to the hydrogens (c) and (d), and from 5.69 to 5.63 ppm, related to hydrogen (a), when these  ...  Figure 1i shows the assignment of 1 H NMR signals for the starting materials: OA (Figure 1i-a) , GA (Figure 1i-b) , and CB (Figure 1i-c) , respectively.  ...  Copyright © 2020 Jorge, Harada, Silva, Campos, Moreli, Shimamoto, Pereira, Oliveira, Tubino, Vila and Balcão.  ... 
doi:10.3389/fphar.2020.00243 pmid:32390824 pmcid:PMC7191306 fatcat:cmldbf6smbg4hlymercry5dbv4

Protein Disulfide Isomerase Modulates the Activation of Thyroid Hormone Receptors

Jessica L. O. Campos, Tabata R. Doratioto, Natalia B. Videira, Helder V. Ribeiro Filho, Fernanda A. H. Batista, Juliana Fattori, Nathalia de C. Indolfo, Marcel Nakahira, Marcio C. Bajgelman, Aleksandra Cvoro, Francisco R. M. Laurindo, Paul Webb (+1 others)
2019 Frontiers in Endocrinology  
(D) Overlap of TRα and TRβ models (B,C). (E) Detail of PDIA1 cysteines and TRα and TRβ cysteines.  ...  Connecting b ′ and a ′ domains, there is a 19-residue short interdomain region, named x-linker, while at the C-terminus region there is a highly acidic extension, involved in calcium binding and a KDEL  ...  Copyright © 2019 Campos, Doratioto, Videira, Ribeiro Filho, Batista, Fattori, Indolfo, Nakahira, Bajgelman, Cvoro, Laurindo, Webb and Figueira.  ... 
doi:10.3389/fendo.2018.00784 fatcat:f5izmzafgfd4xasaxuguqgopsu

Mathematical modeling and determination of thermodynamic properties of jabuticaba peel during the drying process

Cristian F. Costa, Paulo C. Corrêa, Jaime D. B. Vanegas, Fernanda M. Baptestini, Renata C. Campos, Lara S. Fernandes
2016 Revista Brasileira de Engenharia Agrícola e Ambiental - Agriambi  
Drying was carried out in a forced-air circulation oven with a flow of 5.6 m s-1 at temperatures of 40, 50, 60 and 70 °C.  ...  exp(-ct) (3) Verma MR = a exp(-kt) + (1 -a) exp(-bt) (4) Midilli MR = a exp(-kt c ) + bt (5) Logarithmic MR = a exp(-kt) + b (6) Page MR = exp(-kt c ) (7) where: a, b and c -coefficients of the models,  ...  The drying times corresponding to the temperatures of 40, 50, 60 and 70 °C were, respectively, 10.50, 8.00, 6.50 and 5.50 h.  ... 
doi:10.1590/1807-1929/agriambi.v20n6p576-580 fatcat:dcwahffa7bhkffctrzgsph22q4

R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome

Fernanda C. P. Mesquita, Paulo C. Arantes, Tais H. Kasai-Brunswick, Dayana S. Araujo, Fernanda Gubert, Gustavo Monnerat, Danúbia Silva dos Santos, Gabriel Neiman, Isabela C. Leitão, Raiana A. Q. Barbosa, Jorge L. Coutinho, Isadora M. Vaz (+7 others)
2019 Scientific Reports  
The objective of this work was to study a type 2 long QT syndrome (LQTS2)-associated mutation (c.1600C > T in KCNH2, p.R534C in hERG) in CM-iPSC.  ...  Quantification of hERG fluorescence intensity signal in the membrane (b) and intracellular space (c). CTRL-iPSC (n = 25); LQTS2-iPSC1 (n = 22); LQTS2-iPSC2 (n = 20); LQTS2-CRISPR (n = 17).  ...  Primary antibodies were incubated at 4 °C for 12 h.  ... 
doi:10.1038/s41598-019-55837-w pmid:31844156 fatcat:gzrmwtqtj5eujng5qg26csrukq

Reprogramming to a pluripotent state modifies mesenchymal stem cell resistance to oxidative stress

Karina D. Asensi, Rodrigo S. Fortunato, Danúbia S. dos Santos, Thaísa S. Pacheco, Danielle F. de Rezende, Deivid C. Rodrigues, Fernanda C. P. Mesquita, Tais H. Kasai-Brunswick, Antonio C. Campos de Carvalho, Denise P. Carvalho, Adriana B. Carvalho, Regina C. dos S. Goldenberg
2014 Journal of Cellular and Molecular Medicine  
Figure S3 S3 Light microscopy of ESC (H9: A and B; HES3: E and F) and iPSC in culture (mb-iPSC: C and D; ihFib3.2: G and H).  ...  MTT assay showing cell viability in response to increasing doses of H 2 O 2 in mbMSC (n = 6; A), H9 (n = 4; B) and mb-iPSC (n = 4; C).  ... 
doi:10.1111/jcmm.12226 pmid:24528612 pmcid:PMC4119388 fatcat:tqbgzz2675cp3osjn4p3heyhcy

Adipose Tissue-Derived Mesenchymal Stromal Cells Protect Mice Infected with Trypanosoma cruzi from Cardiac Damage through Modulation of Anti-parasite Immunity

Debora B. Mello, Isalira P. Ramos, Fernanda C. P. Mesquita, Guilherme V. Brasil, Nazareth N. Rocha, Christina M. Takiya, Ana Paula C. A. Lima, Antonio C. Campos de Carvalho, Regina S. Goldenberg, Adriana B. Carvalho, Eric Dumonteil
2015 PLoS Neglected Tropical Diseases  
(B) Macroscopic view of CFU-F assay showing colonies of ASC stained by Giemsa. (C) Microscopic view exemplifying one colony of ASC also stained by Giemsa.  ...  (C-G) H&E and (H-J) Sirius Red staining of heart tissue sections. (C) Non-infected animals showed normal myocardial fibers.  ... 
doi:10.1371/journal.pntd.0003945 pmid:26248209 pmcid:PMC4527728 fatcat:ikd7wpis6vcovhoxk6rfkfy33m

Synthesis of a new class of naphthoquinone glycoconjugates and evaluation of their potential as antitumoral agents

Vinicius R. Campos, Anna C. Cunha, Wanderson A. Silva, Vitor F. Ferreira, Carla Santos de Sousa, Patrícia D. Fernandes, Vinícius N. Moreira, David R. da Rocha, Flaviana R. F. Dias, Raquel C. Montenegro, Maria C. B. V. de Souza, Fernanda da C. S. Boechat (+2 others)
2015 RSC Advances  
the 1 H NMR spectrum of derivative 9c (CDCl 3 , 500 MHz)…………….13 13 C / APT NMR spectrum of derivative 9c (CDCl 3 , 125 MHz)………………………..14 1 H NMR spectrum of derivative 11a (CDCl 3 , 500 MHz)…………………………  ...  …...15 Expansion of the 1 H NMR spectrum of derivative 11a (CDCl 3 , 500 MHz)…………...16 Expansion of the 1 H NMR spectrum of derivative 11a (CDCl 3 , 500 MHz)…………...17 13 C / APT NMR spectrum of derivative  ... 
doi:10.1039/c5ra19192k fatcat:hkmzbz4ncjgtbfbqgduhe233lq

Bonding strategies to full-contour zirconia: Zirconia pretreatment with piranha solution, glaze and airborne-particle abrasion

Sabrina A. Feitosa, Nelson B. Lima, Walter K. Yoshito, Fernanda Campos, Marco A. Bottino, Luiz F. Valandro, Marco C. Bottino
2017 International Journal of Adhesion and Adhesives  
A B S T R A C T This study aimed to evaluate the effect of various zirconia surface pretreatments on the adhesion between full contour 3Y-TZP zirconia and glaze, and the shear bond strength (SBS) between  ...  ESPE), and (C) glaze application.  ...  Fig. 1 .Fig. 2 . 12 Representative SEM micrographs of the FCZ ceramic surface after being subjected to (A) piranha solution (H 2 SO 4 /30%H 2 O 2 = 3:1), (B) airborne-particle abrasion with Cojet ® (3M  ... 
doi:10.1016/j.ijadhadh.2017.05.007 fatcat:p6t7uej24jg6tez3m6jgsxerky

Effects of the compounds MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats

André A. Santos, Paulo C. Leal, Maria I. A. Edelweiss, Tiago Giuliani Lopes, João B. Calixto, Fernanda B. Morrone, Maria M. Campos
2010 Naunyn-Schmiedeberg's Archives of Pharmacology  
MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats Santos-Júnior AA, Leal PC, Edelweiss MIA, Lopes TG, Calixto JB, Morrone FB, Campos  ...  (B) CYP: severe hemorrhagic cystitis with edema, transmural hemorrhage, mucosal ulceration, and inflammation. (C) Mesna: near normal appearance.  ...  (B) CYP: severe hemorrhagic cystitis with edema, transmural hemorrhage, mucosal ulceration, and inflammation. (C) Mesna: near normal appearance.  ... 
doi:10.1007/s00210-010-0555-0 pmid:20809237 fatcat:bpyaxdf25zemfkbshvfaovpjgi

"Now I Can Do Better": A Study of Obese Women's Experiences following a Nonprescriptive Nutritional Intervention

Mariana D. Ulian, Bruno Gualano, Fabiana B. Benatti, Patricia L. de Campos-Ferraz, Odilon J. Roble, Bruno T. Modesto, Bruna C. Brito, Karina A. Murakawa, Mariana D. Torre, Aline C.C. Tritto, Ramiro F. Unsain, Priscila M. de Sato (+1 others)
2015 Clinical Medicine Insights: Women's Health  
Eligible participants met the following criteria: (a) female, (b) aged 25-50 years, (c) a BMI higher than 30 kg/m 2 , (d) literate, (e) not suffering from diabetes mellitus, (f) not engaged in other nutritional  ...  neutralize food (ie, classify food nondichotomously), (c) build social support external to the intervention, and (d) identify enjoyable activities.  ... 
doi:10.4137/cmwh.s23163 pmid:26417206 pmcid:PMC4573064 fatcat:q3qugtq3fban3bxsubvot5fg4u

SAT-179 Increased Telomere Length in Adrenocortical Tumors Is Associated with Abnormal Expression of Chromatin Remodelling Factors

Monica F Stecchini, Ana Carolina Bueno, Leandra N Z Ramalho, Fernando S Ramalho, Rodrigo T Calado, Fernanda B Coeli-Lacchini, Mateus R Campos, Davi C Aragon, Ayrton C Moreira, Silvia R Brandalise, Margaret Castro, Jose A Yunes (+1 others)
2020 Journal of the Endocrine Society  
Background: The pathogenesis of adrenocortical tumors (ACTs) in the pediatric population is partially known, and few prognostic factors have been identified in this age group. Recently, ATRX and DAXX have been implicated in the pathogenesis and prognosis of a variety of cancers. Their altered function has been shown to affect telomere length through a telomerase-independent mechanism. Objective: To investigate ATRX and DAXX gene expression, ATRX and DAXX protein expression, and telomere length,
more » ... as well as their clinical significance, in ACT samples from pediatric patients. Methods: The records of 110 pediatric patients with available ACT samples were reviewed. ATRX, DAXX, TERT and TERC gene expression was assessed by qPCR (n = 100 ACTs; n = 12 normal adrenals). ATRX and DAXX protein expression was assessed by IHC (n = 45 ACTs). Telomere length was assessed by qPCR (n = 64 ACTs). For survival analysis, Kaplan-Meier curves were obtained. For association analysis, simple linear regression models were adjusted. Results: Most patients were female (70.9%) and harbored germline TP53 mutations (90.2%). Median age at diagnosis was 21.1 months (2.1 – 199). Younger patients (< 3 years) had better survival (p < 0.01), while those with metastasis at diagnosis and carcinomas (classified by the Wieneke score) had worse survival (p < 0.01). ATRX gene expression was decreased (p < 0.01), while DAXX gene expression was increased (p < 0.01) in ACTs, compared to normal adrenals. ATRX gene expression was even lower in the context of the germline TP53 (R337H) mutation (p < 0.01). TERT expression was not detected in ACTs or normal adrenals, and TERC expression was not altered (p = 0.69). ATRX protein expression was lost in the majority of ACTs (95.6%), while DAXX was lost in a minority (21.1%). There was no association between gene or protein expression and disease-free or overall survival. There was a significant association between decreased ATRX and DAXX gene expression and increased telomere length (p < 0.01 and p = 0.03, respectively). Conclusion: In pediatric ACTs, decreased ATRX and DAXX gene expression was associated with increased telomere length, independently of TERT or TERC expression. In these tumors, ATRX gene expression was decreased and ATRX protein expression was overall lost, while DAXX gene expression was increased and DAXX protein expression was overall retained. No significant association between these alterations and prognosis was found in this cohort. These findings suggest that ATRX and DAXX altered function may be more involved in the pathogenesis of pediatric ACTs than in the prognosis of the affected patients.
doi:10.1210/jendso/bvaa046.1369 fatcat:nd7ozfmnbrbshbp2zztwakxjya

Ureaplasma diversum Genome Provides New Insights about the Interaction of the Surface Molecules of This Bacterium with the Host

Lucas M. Marques, Izadora S. Rezende, Maysa S. Barbosa, Ana M. S. Guimarães, Hellen B. Martins, Guilherme B. Campos, Naíla C. do Nascimento, Andrea P. dos Santos, Aline T. Amorim, Verena M. Santos, Sávio T. Farias, Fernanda Â. C. Barrence (+8 others)
2016 PLoS ONE  
The complete genome showed 973,501 bp in a single circular chromosome, with 28.2% of G+C content.  ...  The temperatures were: injector 250°C and the oven programmed from 50°C to 220°C at 40°C min -1 .  ...  (B) Gene expression of Toll-like receptors 2 in macrophage J774 culture after infection with U. diversum ATCC 49782 strain compared to the uninfected cells.  ... 
doi:10.1371/journal.pone.0161926 pmid:27603136 pmcid:PMC5015763 fatcat:2lj3kb2ynjfqfdfgpgls6tgswa
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