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Exploring Low-degree Nodes First Accelerates Network Exploration [article]

Stefania Costantini, Pasquale De Meo, Angelo Giorgianni, Valentina Migliorato, Alessandro Provetti, Federico Salvia
2020 arXiv   pre-print
Meo et al. 2014; Pons and Latapy 2006 ].  ...  Random walks (RWs) have been applied in a broad range of graph analytic tasks such as the ranking of individuals in a social network [Newman 2005 ] and the segmentation of large virtual communities [De  ... 
arXiv:2005.08050v1 fatcat:ippnck2onzfp7esjgr72vf4d3q

Formal Analysis of Vulnerabilities of Web Applications Based on SQL Injection [chapter]

Federico De Meo, Marco Rocchetto, Luca Viganò
2016 Lecture Notes in Computer Science  
BB TB EB UQ SO SQ AB DE AB DE AB DE AB DE AB DE AB DE SELECT UPDATE DELETE INSERT In a Boolean-Based SQLi (BB), an intruder inserts into an HTTP parameter, which is used by a web app to write a SQL query  ...  remarks: (1) since all state-of-the-art DBMS are vulnerable to SQLi, we won't distinguish between different dialects of SQL and simply write "SQL query"; (2) AB abbreviates authentication bypass and DE  ... 
doi:10.1007/978-3-319-46598-2_13 fatcat:ipbs4yafwzbupk5jeptqsuz4fq

Exploring Low-degree nodes first accelerates Network Exploration

Stefania Costantini, Pasquale De Meo, Angelo Giorgianni, Valentina Migliorato, Alessandro Provetti, Federico Salvia
2020 12th ACM Conference on Web Science  
Meo et al. 2014; Pons and Latapy 2006 ].  ...  Random walks (RWs) have been applied in a broad range of graph analytic tasks such as the ranking of individuals in a social network [Newman 2005 ] and the segmentation of large virtual communities [De  ... 
doi:10.1145/3394231.3397914 dblp:conf/websci/CostantiniMGMPS20 fatcat:qggx676vvfbs7nqrkrmii6a5iy

Clinical Application of Antibacterial Hydrogel and Coating in Orthopaedic and Traumatology Surgery

Daniele De Meo, Giancarlo Ceccarelli, Giancarlo Iaiani, Federico Lo Torto, Diego Ribuffo, Pietro Persiani, Ciro Villani
2021 Gels  
Antimicrobial Coating DAC (Hydrogel) ETN PROtect (Coating) Type of implants on which is applicable • Plates • Screws • Nails • Uncemented prosthesis Only available for Expert Tibial Nail (De  ... 
doi:10.3390/gels7030126 pmid:34462412 pmcid:PMC8406094 fatcat:orwte7tqdnfu7lkmrvzkr2vkdm

Mechanical and elution properties of G3 Low Viscosity bone cement loaded up to three antibiotics

Giorgio Cacciola, Federico De Meo, Pietro Cavaliere
2018 Journal of Orthopaedics  
Conflicts of interest Giorgio Cacciola and Federico De Meo have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation  ... 
doi:10.1016/j.jor.2018.08.035 pmid:30237670 pmcid:PMC6143749 fatcat:pt4vctdfjzel5kxs6m6foqzbtm

Formal Analysis of Vulnerabilities of Web Applications Based on SQL Injection (Extended Version) [article]

Federico De Meo, Marco Rocchetto, Luca Viganò
2016 arXiv   pre-print
BB TB EB UQ SO SQ AB DE AB DE AB DE AB DE AB DE AB DE SELECT UPDATE DELETE INSERT 3.1 Boolean-Based SQLi (BB) In a BB, an intruder inserts into an HTTP parameter, which is used by a web app to write a  ...  stateof-the-art DBMS are vulnerable to SQLi, we won't distinguish between different dialects of SQL and simply write "SQL query"; (2) for brevity, in the table we write AB for authentication bypass and DE  ... 
arXiv:1605.00358v2 fatcat:3i46qmej3bfmpbamwhj6jwp57y

A Formal Approach to Exploiting Multi-stage Attacks Based on File-System Vulnerabilities of Web Applications [chapter]

Federico De Meo, Luca Viganò
2017 Lecture Notes in Computer Science  
Web applications require access to the file-system for many different tasks. When analyzing the security of a web application, security analysts should thus consider the impact that file-system operations have on the security of the whole application. Moreover, the analysis should take into consideration how file-system vulnerabilities might interact with other vulnerabilities leading an attacker to breach into the web application. In this paper, we first propose a classification of filesystem
more » ... tion of filesystem vulnerabilities, and then, based on this classification, we present a formal approach that allows one to exploit file-system vulnerabilities. We give a formal representation of web applications, databases and filesystems, and show how to reason about file-system vulnerabilities. We also show how to combine file-system vulnerabilities and SQL-Injection vulnerabilities for the identification of complex, multi-stage attacks. We have developed an automatic tool that implements our approach and we show its efficiency by discussing several real-world case studies, which are witness to the fact that our tool can generate, and exploit, complex attacks that, to the best of our knowledge, no other state-of-the-art-tool for the security of web applications can find.
doi:10.1007/978-3-319-62105-0_13 fatcat:b7it64t7ovfmtkjq4zlydlaj4a

Gentamicin-Coated Tibia Nail in Fractures and Nonunion to Reduce Fracture-Related Infections: A Systematic Review

Daniele De Meo, Federico M. Cannari, Luisa Petriello, Pietro Persiani, Ciro Villani
2020 Molecules  
The incidence of a fracture-related infection (FRI) can reach 30% of open tibia fractures (OTF). The use of antibiotic-coated implants is one of the newest strategies to reduce the risk of infection in orthopedic surgery. The aim of this study was to investigate the efficacy and safety of a gentamicin-coated tibia nail in primary fracture fixation (FF) and revision surgery (RS) of nonunion cases in terms of FRI incidence. We conducted a systematic review according to the PRISMA checklist on
more » ... MA checklist on Pub-Med, Cochrane, and EMBASE. Of the 32 studies, 8 were included, for a total of 203 patients treated: 114 were FF cases (63% open fractures) and 89 were RS cases, of which 43% were infected nonunion. In the FF group, four FRI were found (3.8%): three OTF (Gustilo-Anderson III) and one closed fracture; bone healing was achieved in 94% of these cases. There were four relapses of infection and one new onset in the RS group; bone healing occurred in 88% of these cases. No side effects were found. There were no significant differences in terms of FRI, nonunion, and healing between the two groups. Gentamicin-coated tibia nail is an effective therapeutic option in the prophylaxis of high-risk fracture infections and in complex nonunion cases.
doi:10.3390/molecules25225471 pmid:33238408 fatcat:wg64piuwajaebbpgxznwxfna24

MobSTer: A model-based security testing framework for web applications

Michele Peroli, Federico De Meo, Luca Viganò, Davide Guardini
2018 Software testing, verification & reliability  
Web applications have become one of the preferred means for users to perform a number of crucial and security-sensitive operations such as selling and buying goods or managing bank accounts, official documents, personal health records, smart houses and so on. The pervasive adoption of such web applications calls for an extensive security analysis in order to avoid attacks. Penetration testing is the most common approach for testing the security of web applications, but model-based security
more » ... based security testing has been steadily maturing into a viable alternative and/or complementary approach. Penetration testing is very efficient but the experience of the security analyst is crucial; model-based security testing relies on formal methods but the security analyst has to first create a suitable model of the web application. In this paper, we introduce MobSTer, a formal and flexible model-based security testing framework that contributes to filling the gap between these two security testing approaches. The main idea underlying this framework is that the use of model-checking techniques can automate the search for possible vulnerable entry points in the web application, i.e., it permits an analyst to perform security testing without missing important checks. Moreover, the framework also allows for reuse: the analyst can collect her expertise into the framework and (re)use it during future tests on possibly different web applications. We have implemented MobSTer as a prototype and applied it to test a number of case studies to assess its strength and concretely evaluate it with respect to four state-of-the-art tools normally used by penetration testers. Test Execution Engine Model Checker Test Web Application Model CE(s) Web Application Login • simplicity (e.g., of the modeling activity), 2 Throughout the paper we will refer to the security analyst as "she". 3 The formalization used in our approach can also be adapted to represent software that is not web-based. However, our concretization phase (which is important for testing the results of the formal phase) works specifically for web-based software. Thus, migrating the approach to non-web-based software would require one to address different challenges related to the low-level behavior of such software. • reusability (in our framework, actions are associated with data they handle and properties they have, thus, reusing actions also means to reuse these associations during the testing of different web applications). Actions are defined by the security analyst who decides the abstraction level and the granularity she wishes to consider. As a concrete example of the actions' characteristics (i.e., their use in the framework as well as the expertise used in their identification), consider the "login" functionality. Web applications usually employ one of the following types of authentication mechanism (we also add the attacks that the security analyst can exploit in order to attack the action): • Basic Authentication: the tester can try to perform a brute-force attack, and the password is sniffable if not passed via HTTPS. • HTTP Digest Authentication: brute-force attacks and man-in-the-middle attacks are possible. • Form-based Authentication: brute-force attacks are possible, injection vulnerabilities (e.g., , Cross-Site Scripting XSS [22], etc.) have to be tested, and the attacker should try to capture the authentication token (i.e., session tokens or cookies). 4 The source code of the MobSTer tool is available at https://github.com/REGIS-lab/MobSTer.
doi:10.1002/stvr.1685 fatcat:6euvzblhmvffbaxgc4i5eax5qa

High values of pelvic incidence: A possible risk factor for zigoapophyseal facet arthrosis in young

Giorgio Cacciola, Alessandro Pisani, Pietro Cavaliere, Bruno Pitrone, Domenico Rizzo, Giuseppina Rizzo, Filippo Cascio, Federico De Meo, Andrea Barbanera
2018 Journal of Orthopaedics  
A B S T R A C T In humans the acquisition of the bipedalism caused different structural changes to achieve the new functional demands. In particular, several changes have occurred in the spine and pelvis. In recent years the sagittal morphology of the spine and pelvis has become one of the most focused topics in spine research. The sample consists of 348 volunteers, with no history of low back pain, without any previous major trauma at the spine or at the pelvis. Aged between 20 and 29 years.
more » ... 20 and 29 years. The presence and severity of zygoapophyseal facet arthrosis were investigated in accordance with Pathria's classification (it considered four parameters: width of interarticular space, the presence of osteophytes, the presence of facet hypertrophy and presence of areas of bone erosion). Volunteers were divided into two group based on sagittal balance subtype classified by Roussouly in 2005. 98 volunteers (35.76%) belongs to group A (subtype I and II), and 176 volunteers (64.24%) belongs to group III and IV. The different weight distribution in the lumbar spine suggests that different subtype of sagittal balance could develop zygoapophyseal facet arthrosis more frequently. Considering the different Groups, a statistically significant difference was found: people belonging in group B (subtype III and IV), shows a prevalence of 36,36% compared with a prevalence of 24.5% for group A (subtype I and II).
doi:10.1016/j.jor.2018.02.011 pmid:29881147 pmcid:PMC5990124 fatcat:z3elwuzywzfdznycss6ju447ya

SpliceAid-F: a database of human splicing factors and their RNA-binding sites

Matteo Giulietti, Francesco Piva, Mattia D'Antonio, Paolo D'Onorio De Meo, Daniele Paoletti, Tiziana Castrignanò, Anna Maria D'Erchia, Ernesto Picardi, Federico Zambelli, Giovanni Principato, Giulio Pavesi, Graziano Pesole
2012 Nucleic Acids Research  
A comprehensive knowledge of all the factors involved in splicing, both proteins and RNAs, and of their interaction network is crucial for reaching a better understanding of this process and its functions. A large part of relevant information is buried in the literature or collected in various different databases. By hand-curated screenings of literature and databases, we retrieved experimentally validated data on 71 human RNA-binding splicing regulatory proteins and organized them into a
more » ... d them into a database called 'SpliceAid-F' (http://www.caspur.it/SpliceAidF/). For each splicing factor (SF), the database reports its functional domains, its protein and chemical interactors and its expression data. Furthermore, we collected experimentally validated RNA-SF interactions, including relevant information on the RNAbinding sites, such as the genes where these sites lie, their genomic coordinates, the splicing effects, the experimental procedures used, as well as the corresponding bibliographic references. We also collected information from experiments showing no RNA-SF binding, at least in the assayed conditions. In total, SpliceAid-F contains 4227 interactions, 2590 RNA-binding sites and 1141 'no-binding' sites, including information on cellular contexts and conditions where binding was tested. The data collected in SpliceAid-F can provide significant information to explain an observed splicing pattern as well as the effect of mutations in functional regulatory elements.
doi:10.1093/nar/gks997 pmid:23118479 pmcid:PMC3531144 fatcat:juei6b4xrremll3bwz262js4zm

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy

A. Desantis, T. Bruno, V. Catena, F. De Nicola, F. Goeman, S. Iezzi, C. Sorino, M. Ponzoni, G. Bossi, V. Federico, F. La Rosa, M. R. Ricciardi (+12 others)
2015 EMBO Journal  
Mammalian target of rapamycin (mTOR) is a key protein kinase that regulates cell growth, metabolism, and autophagy to maintain cellular homeostasis. Its activity is inhibited by adverse conditions, including nutrient limitation, hypoxia, and DNA damage. In this study, we demonstrate that Che-1, a RNA polymerase II-binding protein activated by the DNA damage response, inhibits mTOR activity in response to stress conditions. We found that, under stress, Che-1 induces the expression of two
more » ... sion of two important mTOR inhibitors, Redd1 and Deptor, and that this activity is required for sustaining stressinduced autophagy. Strikingly, Che-1 expression correlates with the progression of multiple myeloma and is required for cell growth and survival, a malignancy characterized by high autophagy response.
doi:10.15252/embj.201489920 pmid:25770584 pmcid:PMC4426481 fatcat:7qxrhw25enab3lsmispt7qgdeq

Does Pelvic Incidence Influence the Morphology of the Sacroiliac Joint?

Giorgio Cacciola, Federico De Meo, Angelo Favaloro, Alessandro Pisani, Piero Cavaliere, Andrea Barbanera, Elena Filippini, Carmelo Milazzo, Debora Di Mauro
2017
Pelvic Incidence is defined as the angle between the perpendicular line to the upper plate of S1 at its midpoint and the line between this point and the center of bicoxofemoral line, it describes the position of femural heads in relation to sacrum. Recently some authors described a direct correlation between high values of PI and large AP pelvic axis (horizontal pelvis) and a wide pelvic ring [1]. Also the acetabular orientation is influenced by PI ; high values of PI means a more vertical
more » ... more vertical acetabulum. Having regard to the relationship between PI and the main structures involved in the load transfer, to date no studies that correlate the morphology of the Sacroiliac Joint (SiJ) and PI were performed. The aim of this study is to evaluate the different morphology of the auricular surface of the sacrum comparing two groups of healthy young people with low (<40°) and high (>40°) PI. We retrospectively analysed 51 consecutive young (between 20 and 35 y.o.) people. After the evaluation of PI the sample was divided into two groups: 31 people belong to the group A (PI < 40°) and 20 people belong the the group B (PI >40°). The following morphological parameters of the SiJ were analysed: length of long axis (LLA), length of short axis (LSA), length of oblique axis (LOA), ratio between long and short axis (RLSA), angle between axis (ABA) and surface; global shape of the joint was evaluated; two new parameters were introduced, SiJ Tilt (SiJT), defined as the angle between the vertical line and the long axis of the SiJ and SiJ Slope (SiJS), defined as the angle between the horizontal line and the short axis of the SiJ. We found a strong statistically significant correlations (p-value 0.05) between PI and RLSA, shape, ABA, SiJT and SiJS; a weaker correlations (p-value 0.10) between PI and LLA, LSA were observed; no statistically significant correlation between PI and LOA and surface were observed. The results underline that there is a strong correlation between pelvic morphology and SiJ anatomy. Further studies, abo [...]
doi:10.13128/ijae-21429 fatcat:jg2exaprfrhn7dqohbfseyrzg4

Page 338 of Analecta Bollandiana Vol. 34-35, Issue [page]

1915 Analecta Bollandiana  
Federico Borromeo. Milano, Bertarelli, 1910, in-8°, 30 pp. Extrait de San Carlo Borromeo, etc., n° 25, Novembre, 1910. 17. — Lettere edite ed inedite di S. Carlo Borromeo al card. G.  ...  Carlo Borro- meo nel 1566 alla badia dei SS. Gratiano e Felino in Arona, dans Rivista storica benedettina, t. 1V (1910), p. 571-84. 25.— * F. GIACOMELLO. Padova e S.  ... 

Page 147 of National Union Catalog Vol. 17, Issue [page]

1942 National Union Catalog  
Federico Borro- meo. Milano, Stamperia Pulini, 1795. 76 p. 18™. 10-12708 Library of Congress Borromini, Francesco, 1599-1667. .  ...  Borromeo, Federico, cardinal, 1564-1631. II libro intitolato La gratia de’ principi di Federico Bor- romeo In Milano, ™.pe.xxx11. 3 p. L, 207, 3, p. 329°. Title vignette, engraved.  ... 
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