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Feature-Specific Profiling [article]

Leif Andersen, Vincent St-Amour, Jan Vitek, Matthias Felleisen
2018 arXiv   pre-print
Feature-specific profilers help programmers find expensive uses of specific features of their language.  ...  To address this issue, we introduce feature-specific profiling, a technique that reports performance costs in terms of linguistic constructs.  ...  Fig. 1 . 1 Feature profile for FizzBuzz Fig. 3 . 3 Output Traditional Profiler (le ) and Feature-Specific Profiler (right) Fig. 4 . 4 Architecture for an FSP Fig. 5 . 5 Recording paths in a tree  ... 
arXiv:1809.04151v1 fatcat:2vm5vorw3jgmhps64dljocxaty

Feature-Specific Profiling [chapter]

Vincent St-Amour, Leif Andersen, Matthias Felleisen
2015 Lecture Notes in Computer Science  
After explaining the architecture of our feature-specific profiler, the paper presents the evidence in support of adding feature-specific profiling to the programmer's toolset.  ...  With a feature-specific profiler, a programmer can identify specific instances of language features that are responsible for performance problems.  ...  Our feature-specific profiler overcomes both of these problems.  ... 
doi:10.1007/978-3-662-46663-6_3 fatcat:6hhwke2jmrez3gb62xx7x3jrwq

Systematic profiling of the bacterial phosphoproteome reveals bacterium-specific features of phosphorylation

Miao-Hsia Lin, Naoyuki Sugiyama, Yasushi Ishihama
2015 Science Signaling  
often accompanied by kinase-mediated phosphorylation events, the differences in phosphorylation preferences between bacteria and eukaryotes revealed by this study could be useful in identifying bacterial-specific  ...  The resulting large-scale bacterial phosphoproteome resource has enabled us to uncover various bacterium-specific phosphorylation features, including high-confidence phosphorylation motifs and the notably  ...  Extensive genetic and biochemical experiments will be required to establish in detail the mechanisms of molecular regulation, as well as to discover species-specific features that might be applied to the  ... 
doi:10.1126/scisignal.aaa3117 pmid:26373674 fatcat:saequj66uzefbjkyvs4o6b7nle

Williams Syndrome-Specific Neuroarchitectural Profile and Its Associations with Cognitive Features [article]

Chun Chieh Fan, Timothy T. Brown, Hauke Bartsch, Joshua M. Kuperman, Donald J. Hagler, Andrew Schork, Eric Halgren, Anders Dale
2016 bioRxiv   pre-print
Here, we used a novel approach to derive a WS specific neuroarchitectural profile and tested its association with cognitive features of WS.  ...  Using a WS adult cohort (n = 43), we trained a logistic elastic-net model to extract a sparse representation of WS specific neuroarchitectural profile.  ...  In this independent cohort, the WS specific neuroarchitectural profile retains high specificity to WS, achieving AUC with 1.0 (Figure 1) . Features in the WS specific neuroarchitectural profile .  ... 
doi:10.1101/060764 fatcat:q7lele7uwzg7jebtzdukc5pn3e

Combining territory and competitiveness in EU Regional Policy? Analyzing ERDF investment profiles in regions with specific geographical features

Benito Giordano, Alexandre Dubois
2018 Figshare  
Table A2 : A2 List of 15 NUTS2 regions with specific geographical features selected as case studies (Source: ADE, 2012) REGION (NUTS2) NAME Member State Operational Programme (OP) at NUTS2 level  ...  Method Regions are characterised based on the extent of the coverage of a geographic specificity within its borders.  ... 
doi:10.6084/m9.figshare.6887096.v1 fatcat:hcuu7pfuzbaz5dhtvgaqgobof4

Using Class-Specific Feature Selection for Cancer Detection with Gene Expression Profile Data of Platelets

Lei-ming Yuan, Yiye Sun, Guangzao Huang
2020 Sensors  
class-specific features comparable.  ...  The elastic net was used to select class-specific features for the binary classification problems, and the probabilistic support vector machine was used to make the outputs of the binary classifiers with  ...  the class-specific features.  ... 
doi:10.3390/s20051528 pmid:32164283 fatcat:4g4r34zfzfgohhswtcgiiwpz4a

Williams syndrome-specific neuroanatomical profile and its associations with behavioral features

Chun Chieh Fan, Timothy T. Brown, Hauke Bartsch, Joshua M. Kuperman, Donald J. Hagler, Andrew Schork, Yvonne Searcy, Ursula Bellugi, Eric Halgren, Anders M. Dale
2017 NeuroImage: Clinical  
Features in the WS-specific neuroanatomical profile The cortical surface features extracted by the model are shown in Fig. 2 .  ...  Nevertheless, the robust performance of the WS-specific neuroanatomical profile in our child cohort suggests these features are already expressed during childhood.  ... 
doi:10.1016/j.nicl.2017.05.011 pmid:28560159 pmcid:PMC5443907 fatcat:jnm4xdixqbhgvdxjtprhcobiku

Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features [article]

Teresa Rayon, Rory J Maizels, Christopher Barrington, James Briscoe
2021 bioRxiv   pre-print
Comparison with existing mouse datasets revealed the overall similarity of mouse and human neural tube development while highlighting specific features that differed between species.  ...  To address this, we used single cell mRNA sequencing to profile cervical and thoracic regions in four human embryos of Carnegie Stages (CS) CS12, CS14, CS17 and CS19 from Gestational Weeks (W) 4-7.  ...  S3 Further characterization of human-specific features of neural progenitors and visceral motor neurons.  ... 
doi:10.1101/2021.04.12.439474 fatcat:2hyfmlgi5jhkpfl42e6hjff5ha

Auditory Profiles of Classical, Jazz, and Rock Musicians: Genre-Specific Sensitivity to Musical Sound Features

Mari Tervaniemi, Lauri Janhunen, Stefanie Kruck, Vesa Putkinen, Minna Huotilainen
2016 Frontiers in Psychology  
features.  ...  However, musicians involved in different musical genres may display highly differentiated auditory profiles according to the demands set by their genre, i.e., varying importance of different musical sound  ...  Rhythm Modulation (Short DISCUSSION We compared the auditory profiles of classical, jazz, and rock musicians to those of non-musicians in encoding various sound features.  ... 
doi:10.3389/fpsyg.2015.01900 pmid:26779055 pmcid:PMC4703758 fatcat:7meidwlr5vfsnjxm5xkazmbtmm

Transcriptional Profile of Tuberculosis Antigen–Specific T Cells Reveals Novel Multifunctional Features

Cecilia Lindestam Arlehamn, Gregory Seumois, Anna Gerasimova, Charlie Huang, Zheng Fu, Xiaojing Yue, Alessandro Sette, Pandurangan Vijayanand, Bjoern Peters
2014 Journal of Immunology  
The transcriptional profile of TB-specific memory T cells is similar to CCR6 + CXCR3 + CCR4 2 memory subset in LTBI and HC donors To determine the transcriptional profile of TB-specific memory T cells,  ...  To examine the cytokine profile of these cells, we stimulated CD4 + T cells with TB-specific peptides.  ... 
doi:10.4049/jimmunol.1401151 pmid:25092889 pmcid:PMC4157075 fatcat:rujexqrtbzcctazzuapaapyn2q

2PT138 Features of Amino Acids Changes Determining the Glycan Specificities of Influenza Hemagglutinins : Interaction Energy Profiles(The 50th Annual Meeting of the Biophysical Society of Japan)

Katsumi Omagari
2012 Seibutsu Butsuri  
Tbkyo) 2PT138 Features of Amino Aeids Changes Determining the Glyca" Specificities of Influenza Hemagglutinins: lnteraction Energy Profiles Katsumi Omagari (IVLigtrya City Uhiversity) The interaction  ...  Effects of substitutions at key positions on the HA snd their possib[e contribution to specificities were investigated too.  ... 
doi:10.2142/biophys.52.s128_4 fatcat:l7gge7bkb5bxzgs245uir43gby

Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features

Teresa Rayon, Rory J. Maizels, Christopher Barrington, James Briscoe
2021 Development  
Comparison with mouse revealed the overall similarity of mammalian neural tube development while highlighting human specific features.  ...  To gain insight into the diversity and complexity of cells in the developing human neural tube we used single cell mRNA sequencing to profile cervical and thoracic regions in four human embryos of Carnegie  ...  S3 Further characterization of human-specific features of neural progenitors and visceral motor neurons. (A) Violin plots of PAX?  ... 
doi:10.1242/dev.199711 pmid:34351410 pmcid:PMC8353162 fatcat:yofarpukufbfnmn552coua5atu

Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma [article]

David Hervás-Marín, Faatiemah Higgins, Onofre Sanmartín, Jose Antonio López-Guerrero, M.Carmen Bañó, J. Carlos Igual, Inma Quilis, Juan Sandoval
2019 bioRxiv   pre-print
In this work we carried out a global-scale approach to investigate the DNA-methylation profile in patients at different stages, from premalignant actinic keratosis to low-risk invasive and high-risk non-metastatic  ...  They report that both AK and cSCC methylation patterns display classical features of cancer methylomes.  ...  order to investigate the existence of potential elements of distinction among specific stages of carcinoma development.  ... 
doi:10.1101/777227 fatcat:vozpo7jdpjcurcp4qkgvhqufpe

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

Bertram Bengsch, Takuya Ohtani, Omar Khan, Manu Setty, Sasikanth Manne, Shaun O'Brien, Pier Federico Gherardini, Ramin Sedaghat Herati, Alexander C. Huang, Kyong-Mi Chang, Evan W. Newell, Niels Bovenschen (+3 others)
2018 Immunity  
Moreover, this resource reveals common Tex cell biology and disease specific features.  ...  In sum, high-dimensional profiling of Tex cells identified distinct features of the differentiation landscape for HIVspecific CD8 T cells and TILs.  ... 
doi:10.1016/j.immuni.2018.04.026 pmid:29768164 pmcid:PMC6010198 fatcat:67gzunkckfelndgn3puz5pq34y

Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma

David Hervás-Marín, Faatiemah Higgins, Onofre Sanmartín, Jose Antonio López-Guerrero, M. Carmen Bañó, J. Carlos Igual, Inma Quilis, Juan Sandoval, Qian Tao
2019 PLoS ONE  
In this work we carried out a global-scale approach to investigate the DNA-methylation profile in patients at different stages, from premalignant actinic keratosis to low-risk invasive and high-risk non-metastatic  ...  (PDF) S1 Hervás-Marín D, Higgins F, Sanmartín O, López-Guerrero JA, Bañó MC, Igual JC, et al. (2019) Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous  ...  Epigenetic features in high-risk cSCC Specific changes in gene function related to cell proliferation, cell fate and cell motility could be epigenetically controlled in the transition from low-risk to  ... 
doi:10.1371/journal.pone.0223341 pmid:31860637 pmcid:PMC6924689 fatcat:w6cszv45jvcarcvzb6ul2jwcji
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