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Blind Inverse Gamma Correction with Maximized Differential Entropy [article]

Yong Lee, Shaohua Zhang, Miao Li, Xiaoyu He
2020 arXiv   pre-print
Besides, the corresponding Python code (https://github.com/yongleex/AGT-ME) is also provided for interested users.  ...  Tested on variable datasets, AGT-ME could obtain an accurate estimation of a large range of gamma distortion (0.1 to 3.0), outperforming the state-of-the-art methods.  ...  This work was supported by National Natural Science Foundation of China (Grant Nos. 81900706 and 51705371), the Natural Science Foundation of Jiangsu Province (Grant No. BK20180235).  ... 
arXiv:2007.02246v1 fatcat:dylpgxvosvaxtnrdehv7wwmfqi

CS2-Net: Deep Learning Segmentation of Curvilinear Structures in Medical Imaging [article]

Lei Mou, Yitian Zhao, Huazhu Fu, Yonghuai Liu, Jun Cheng, Yalin Zheng, Pan Su, Jianlong Yang, Li Chen, Alejandro F Frang, Masahiro Akiba, Jiang Liu
2020 arXiv   pre-print
We introduce a new curvilinear structure segmentation network (CS2-Net), which includes a self-attention mechanism in the encoder and decoder to learn rich hierarchical representations of curvilinear structures  ...  of many diseases.  ...  The final output of CAB is defined as F + F over each pixel.  ... 
arXiv:2010.07486v2 fatcat:jfieuh5tqrdannpiqwqpclacea

TIME FOR COFFEE Encodes a Nuclear Regulator in the Arabidopsis thaliana Circadian Clock

Z. Ding, A. J. Millar, A. M. Davis, S. J. Davis
2007 The Plant Cell  
We isolated TIC and found that its mRNA expression is continuously present over the diurnal cycle, and the encoded protein appears to be strictly localized to the nucleus.  ...  We suggest that TIC encodes a nucleus-acting clock regulator working close to the central oscillator.  ...  ACKNOWLEDGMENTS Z.D. was supported by a postdoctoral fellowship provided jointly by the Max Plank Society and the Chinese Academy of Sciences.  ... 
doi:10.1105/tpc.106.047241 pmid:17496120 pmcid:PMC1913727 fatcat:ku6dtkvi6vairbj3xtbess4taq

Peripheral sensory coding through oscillatory synchrony in weakly electric fish

Christa A Baker, Kevin R Huck, Bruce A Carlson
2015 eLife  
In this study, we address how evolutionary divergence in sensory perception relates to the physiological coding of stimuli.  ...  Our findings provide the first evidence for sensory coding through oscillatory synchrony.  ...  This research was supported by the National Science Foundation (IOS-1255396 to BAC) and the National Institutes of Health (DC012452 to CAB).  ... 
doi:10.7554/elife.08163 pmid:26238277 pmcid:PMC4522468 fatcat:3ijh5odrwff4dptoatlegtkede

Sprouting Angiogenesis in Human Pituitary Adenomas

Jie Zhou, Yaomin Hu, Wende Zhu, Chuansheng Nie, Wenxiu Zhao, Alexander T. Faje, Kay E. Labelle, Brooke Swearingen, Hang Lee, E. Tessa Hedley-Whyte, Xun Zhang, Pamela S. Jones (+4 others)
2022 Frontiers in Oncology  
Expression of VEGFC and PGF was highly correlated with the expression of endothelial markers in tumor samples, including CD31, CD34, and ENG (endoglin, a co-receptor for TGFβ).  ...  There was no significant difference in levels of the lymphatic endothelial marker LYVE1 in pituitary tumors compared with normal pituitary gland tissue.  ...  We also quantified the expression of mRNA coding of LYVE1, a marker of lymphatic endothelial cells (38) .  ... 
doi:10.3389/fonc.2022.875219 pmid:35600354 pmcid:PMC9117625 fatcat:nqsopspamzg6jfkjsx64kgwioq

An integrated multimodal model of alcohol use disorder generated by data-driven causal discovery analysis

Eric Rawls, Erich Kummerfeld, Anna Zilverstand
2021 Communications Biology  
AbstractAlcohol use disorder (AUD) has high prevalence and adverse societal impacts, but our understanding of the factors driving AUD is hampered by a lack of studies that describe the complex neurobehavioral  ...  We then employed data-driven CDA to generate a causal model relating phenotypic factors, fMRI network connectivity, and AUD symptom severity, which highlighted a limited set of causes of AUD.  ...  curve for $200 and $40k but not the individual discounting levels.  ... 
doi:10.1038/s42003-021-01955-z pmid:33790384 pmcid:PMC8012376 fatcat:n5x5pcv3frba7ia5fystbik5fe

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes

Vladimir V. Sharoyko, Mia Abels, Jiangming Sun, Lisa M. Nicholas, Ines Guerra Mollet, Jelena A. Stamenkovic, Isabel Göhring, Siri Malmgren, Petter Storm, João Fadista, Peter Spégel, Metodi D. Metodiev (+4 others)
2014 Human Molecular Genetics  
Here, we found that the levels of TFB1M and mitochondrial-encoded proteins, mitochondrial 12S rRNA methylation, ATP production and oxygen consumption were reduced in b-Tfb1m 2/2 islets.  ...  Our findings highlight the role of mitochondrial dysfunction in impairments of b-cell function and mass, the hallmarks of T2D.  ...  Conflict of Interest statement. None declared.  ... 
doi:10.1093/hmg/ddu288 pmid:24916378 fatcat:2ik4y5tnlfdqjcfeleo5qcsnfe

More Gamma More Predictions: Gamma-Synchronization as a Key Mechanism for Efficient Integration of Classical Receptive Field Inputs with Surround Predictions

Martin Vinck, Conrado A. Bosman
2016 Frontiers in Systems Neuroscience  
In this article, we explore the function of gamma-synchronization in the context of predictive and efficient coding theories.  ...  These theories hold that sensory neurons utilize the statistical regularities in the natural world in order to improve the efficiency of the neural code, and to optimize the inference of the stimulus causes  ...  Roelfsema et al. (2004) made recordings from V1 of awake monkeys performing a curve-tracing task, presenting two curved lines simultaneously.  ... 
doi:10.3389/fnsys.2016.00035 pmid:27199684 pmcid:PMC4842768 fatcat:x6riogx7yfbqvhhampo3yy4zna

Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells

Jennifer N. Lynch, David L. Donermeyer, K. Scott Weber, David M. Kranz, Paul M. Allen
2013 Molecular Immunology  
In this study we focus on two mutations in the CDR1␣ loop of the TCR that increased the affinity of a TCR for agonist Hb(64-76)/I-E k by increasing the on-rate of the reaction.  ...  Structural studies of how TCR differences alter T cell specificity have focused on broad variation in the CDR3 loops. However, changes in the CDR1 and 2 loops can also alter TCR recognition of pMHC.  ...  We thank Ted Hansen, Chyi Hseih, and Yina Huang for review of early versions of this manuscript and constructive advice.  ... 
doi:10.1016/j.molimm.2012.08.020 pmid:22982754 pmcid:PMC3467324 fatcat:namde3ecqba7zenya66s2gg7sq

Differential Leaf Age-Dependent Thermal Plasticity in the Keystone Seagrass Posidonia oceanica

Miriam Ruocco, Pasquale De Luca, Lázaro Marín-Guirao, Gabriele Procaccini
2019 Frontiers in Plant Science  
Subsequent variations in the expression of 12 target genes and global DNA methylation level were evaluated in three leaf-age sections (i.e. basal, medium and high) established along the longitudinal axis  ...  Results: Our data revealed, for the first time, the presence of variable leaf age-dependent stress-induced epigenetic and gene-expression changes in seagrasses, underlying photo-physiological and growth  ...  non-coding RNAs (Liu et al., 2015) .  ... 
doi:10.3389/fpls.2019.01556 pmid:31850036 pmcid:PMC6900526 fatcat:pe73cut7qfdbdleeftbhleynme

Design and Development of Driving Simulator Scenarios for Road Validation Studies

Juan F. Dols, Jaime Molina, Francisco J. Camacho, Javier Marín-Morales, Ana M. Pérez-Zuriaga, Alfredo Garcia
2016 Transportation Research Procedia  
The creation of the simulated scenario is very fast based on the geometric design software, making it easier to consulting firms using the system that can evaluate and audit a particular route, obtaining  ...  The Institute of Design and Manufacturing (IDF) of the Polytechnic University of Valencia (UPV) has developed, in collaboration with the Engineering Research Group Highway (GIIC) of the UPV, a low cost  ...  Acknowledgements Authors would like to thank Polytechnic University of Valencia (UPV) that subsidizes the research project CONSIM (PAID 05-2012).  ... 
doi:10.1016/j.trpro.2016.12.038 fatcat:z3z3fmkmj5byhbhvigbuq5cgpq

Post-Quantum Cryptosystems for Internet-of-Things: A Survey on Lattice-Based Algorithms

Rameez Asif
2021 IoT  
They can solve complex mathematical problems almost instantaneously compared to the billions of years of computation needed by traditional computing machines.  ...  Most of the dominant features of lattice-based cryptography (LBC), which holds it ahead in the post-quantum league, include resistance to quantum attack vectors, high concurrent performance, parallelism  ...  Alan Woodward from University of Surrey, UK for the valuable discussions and lectures on post-quantum cryptography. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/iot2010005 fatcat:ja6nldq4mjafhb2bcyzhxa7efu

Fast and Accurate Time Series Classification with WEASEL

Patrick Schäfer, Ulf Leser
2017 Proceedings of the 2017 ACM on Conference on Information and Knowledge Management - CIKM '17  
An important type of TS analysis is classification, which can, for instance, improve energy load forecasting in smart grids by detecting the types of electronic devices based on their energy consumption  ...  On the popular UCR benchmark of 85 TS datasets, WEASEL is more accurate than the best current non-ensemble algorithms at orders-of-magnitude lower classification and training times, and it is almost as  ...  cac cac cab cab cab cac dbc dbd ... ddd ddc cdc cdb bda bda bda bda ... bdb bdc bdc bdc bdc bdc adb ada ... aab bab bab bab bab bab bab bac ...  ... 
doi:10.1145/3132847.3132980 dblp:conf/cikm/SchaferL17 fatcat:5vpsvwtb3fcqtmylxzgkpzrlba

EF-hand protein Ca2+buffers regulate Ca2+influx and exocytosis in sensory hair cells

Tina Pangršič, Mantas Gabrielaitis, Susann Michanski, Beat Schwaller, Fred Wolf, Nicola Strenzke, Tobias Moser
2015 Proceedings of the National Academy of Sciences of the United States of America  
Neuroscience, University Medical Center Göttingen,) and Simone Eichenberger and Valérie Salicio (Unit of Anatomy, University of Fribourg) for excellent technical assistance.  ...  Wong, and members of the InnerEarLab for discussion and comments on the manuscript, and Margitta Köppler, Sonja Blume, Christian Rüdiger, Sandra Gerke, and Christiane Senger-Freitag (Institute for Auditory  ...  fast 17 .  ... 
doi:10.1073/pnas.1416424112 pmid:25691754 pmcid:PMC4352837 fatcat:6lpe2jfpgned5fg7hj576xmaqi

Virulence Markers, Genotypic versus Phenotypic Resistance and New Treatment Strategies in Helicobacter pylori Infection [chapter]

Maria Teresa Mascellino, Massimiliano De Angelis, Dania Al Ismail, Alessandra Oliva
2021 Helicobacter pylori - From First Isolation to 2020 [Working Title]  
The Hp molecuar diagnosis is fast, accurate and reliable over the traditional methods that are expensive and time- consuming.  ...  This chapter aims at studying the microbial virulence determinants and markers of Helicobacter pylori (Hp), the molecular diagnostic of Hp, the growing antibiotic resistance with the related problem of  ...  In fact the vacA gene contains two variables regions: the s-(signal) region encoding part of the signal peptide with the N-terminus of the mature protein (hydrophilic part) and the m-(middle) region encoding  ... 
doi:10.5772/intechopen.97026 fatcat:vs2vt4wgcjdrrjkaze7ahhckbi
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