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The "Waiting Period" of Sensory and Motor Axons in Early Chick Hindlimb: Its Role in Axon Pathfinding and Neuronal Maturation

Guoying Wang, Sheryl A. Scott
2000 Journal of Neuroscience  
Therefore, axons do not require a prolonged period in the plexus region to sort out and project appropriately.  ...  Thus, axons wait in the plexus region for maturational changes to occur in the limb rather than in the neurons themselves.  ...  regulatory mechanisms are far from understood.  ... 
doi:10.1523/jneurosci.20-14-05358.2000 pmid:10884320 fatcat:5q6xkqujzngftfdsccpy5qnkrq

Peripheral Target Regulation of the Development and Survival of Spinal Sensory and Motor Neurons in the Chick Embryo

Jordi Calderó, David Prevette, Xun Mei, Robert A. Oakley, Ling Li, Carol Milligan, Lucien Houenou, Michael Burek, Ronald W. Oppenheim
1998 Journal of Neuroscience  
L2-L8 all project axons posteriorly toward the tail, where they form a novel plexus (arrows) and contribute to the pudendal plexus (double arrowhead).  ...  B, After limb-bud deletion, neither the crural plexus nor the sciatic plexus develops. L1 and L2 typically project axons anteriorly toward thoracic segments (arrowheads).  ... 
doi:10.1523/jneurosci.18-01-00356.1998 pmid:9412513 fatcat:6cy3viqss5clhbh7tfumhn65wm

Building a second brain in the bowel

Marina Avetisyan, Ellen Merrick Schill, Robert O. Heuckeroth
2015 Journal of Clinical Investigation  
Here, we review molecular mechanisms and cellular processes that govern ENS development, identify areas in which more investigation is needed, and discuss the clinical implications of new basic research  ...  Damage to the ENS or developmental defects cause vomiting, abdominal pain, constipation, growth failure, and early death.  ...  Introduction Survival requires elegantly integrated mechanisms that control bowel motility, secretion, and blood flow to permit fluid and nutrient absorption and support waste elimination.  ... 
doi:10.1172/jci76307 pmid:25664848 pmcid:PMC4362233 fatcat:x5espkujfbbmhpdb24epprnh3u

The expression of twisted gastrulation in postnatal mouse brain and functional implications

M. Sun, C. Forsman, C. Sergi, R. Gopalakrishnan, M.B. O'Connor, A. Petryk
2010 Neuroscience  
We show that Twsg1 is expressed in the adult mouse brain in the choroid plexus (CP), hippocampus, and other regions, with the strongest expression observed in CP.  ...  Among the homozygous mutants that survive beyond the first 2 weeks, the prevalence of hydrocephalus is 4.3%, compared to 1.5% in a wild type colony (p=0.0133) between 3 and 10 weeks of life.  ...  From rostral to caudal all papillary projections of the choroid plexus showed an intense signal of the lining epithelium, while no signal was seen in the fibrovascular core of the papillary projections  ... 
doi:10.1016/j.neuroscience.2010.05.026 pmid:20493240 pmcid:PMC2971674 fatcat:yvh43udiwrbkjjcmlgdazpxrru

A Successful Treatment of Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization for Hydrocephalus in Walker-Warburg Syndrome

Tomoko Tanaka, Catharine J. Harris, Sarah S. Barnett, N. Scott Litofsky
2016 Case Reports in Neurological Medicine  
WWS is fatal to most patients early in life with mean survival of 9 months.  ...  This report describes our successful treatment of a patient with WWS and hydrocephalus with Endoscopic Third Ventriculostomy (ETV) with choroid plexus cauterization (CPC).  ...  However, macrocephaly can lead to mechanical instability of cortical mantel, failure of head control, problems with head positioning, skin breakdown, and other difficulties [9] .  ... 
doi:10.1155/2016/7627289 pmid:28116189 pmcid:PMC5223002 fatcat:r76jwq32z5bmfi6ivazhb22fvq

Degeneración de los terminales aferentes primarios de rata luego de lesión extensa por avulsión del plexo braquial

Vilma Muñetón-Gómez, Julian Scott Taylor, Sharon Averill, John V. Priestley, Manuel Nieto-Sampedro
2004 Biomédica: revista del Instituto Nacional de Salud  
Their cell bodies lie within the dorsal root ganglia (DRG) and are conveniently located for the study of the mechanisms controlling regenerative failure because they have axonal branches both in the central  ...  Important breakthroughs in the understanding regeneration failure in an injured CNS have been made by studies of primary afferent neurons.  ...  Their cell bodies lie within the dorsal root ganglia (DRG) and are conveniently located for the study of the mechanisms controlling regenerative failure because they have axonal branches both in the central  ... 
doi:10.7705/biomedica.v24i2.1264 fatcat:uyik6xktfbhi3pagepzevuzn24

Growing Brains: How Adapting to Africa Advanced the Treatment of Infant Hydrocephalus

Benjamin C. Warf
2017 Neurosurgery  
observation that long-term survival for infants with MM and PIH residing in districts near the hospital (CCHU) was unaffected by treatment type, there was equipoise for comparing VPS and ETV/CPC in a  ...  An ETV is created and the choroid plexus is then cauterized in both lateral ventricles from the foramina of Monro to the temporal horns.  ... 
doi:10.1093/neuros/nyx246 pmid:28899048 fatcat:juiorsaj2jgb3l37fhue6gfh2a

Independent Development of Sensory and Motor Innervation Patterns in Embryonic Chick Hindlimbs

Guoying Wang, Sheryl A. Scott
1999 Developmental Biology  
The resulting sensory innervation patterns mapped with the lipophilic dyes DiI and DiA showed that sensory axons projected robustly to muscles in the absence of motoneurons, if motoneurons were eliminated  ...  Moreover, sensory neurons projected appropriately to their usual target muscles under these conditions.  ...  Note that sensory projection patterns are indistinguishable from those in Fig. 7. survive, apparently because they project to ectopic targets nearby (Calderó et al., 1998) .  ... 
doi:10.1006/dbio.1999.9212 pmid:10191048 fatcat:q6ctufkdsbfa7owanl7sgxewiq

Degeneration of primary afferent terminals following brachial plexus extensive avulsion injury in rats

Vilma Muñetón-Gómez, Julian Scott Taylor, Sharon Averill, John V Priestley, Manuel Nieto-Sampedro
2004 Biomédica: revista del Instituto Nacional de Salud  
Important breakthroughs in the understanding regeneration failure in an injured CNS have been made by studies of primary afferent neurons.  ...  Using immunohistochemistry and high resolution light microscopy, brachial plexus rhizotomy in adult rats has proven a reliable model for several neural deficits in humans.  ...  Their cell bodies lie within the dorsal root ganglia (DRG) and are conveniently located for the study of the mechanisms controlling regenerative failure because they have axonal branches both in the central  ... 
pmid:15495598 fatcat:be5qb2zhbvem7a2rmayatcosfy

Chemogenetic activation of intracardiac cholinergic neurons improves cardiac function in pressure overload induced heart failure

Jhansi Dyavanapalli, Aloysius James Hora, Joan B Escobar, John R Schloen, Mary Kate R Dwyer, Jeannette Rodriguez, Christopher F Spurney, Matthew W Kay, David Mendelowitz
2020 American Journal of Physiology. Heart and Circulatory Physiology  
These data suggest that ICG cholinergic neuron activation reduces cardiac dysfunction and improves survival in HF, indicating ICG neuron activation could be a novel target for treating HF.  ...  Heart failure (HF) is characterized by autonomic imbalance with sympathetic hyperactivity and loss of parasympathetic tone.  ...  Anastas Popratiloff of the George Washington Nanofabrication Center for expertise in acquiring the immunohistochemistry images.  ... 
doi:10.1152/ajpheart.00150.2020 pmid:32412778 pmcid:PMC7474442 fatcat:uep4zl56ujagtd3umnqv45lkji

Ectoderm removal prevents cutaneous nerve formation and perturbs sensory axon growth in the chick hindlimb

Marcia G Honig, Suzanne J Camilli, Qing-Shan Xue
2004 Developmental Biology  
These results demonstrate that the target ectoderm is necessary for normal sensory axon growth and guidance in the hindlimb. D  ...  A few days later, when the nerve pattern is mature, axons normally destined for the 'deprived' cutaneous nerve are not segregated appropriately within the plexus.  ...  Initial LFCt nerve formation The absence of the LFCt nerve at St. 30 could, in theory, have been due to the failure of that nerve to form.  ... 
doi:10.1016/j.ydbio.2003.10.025 pmid:14729476 fatcat:5dn6bwgrpbcc5c7rhu6dobeqoq

Neuregulin-1 is essential for nerve plexus formation during cardiac maturation

Daniel Brown, Leigh Ann Samsa, Cade Ito, Hong Ma, Karla Batres, Rima Arnaout, Li Qian, Jiandong Liu
2017 Journal of Cellular and Molecular Medicine  
plexus such that inadequate innervation leads to deficits in cardiac maturation, function and survival.  ...  Given that the autonomic nervous system normally exerts fine control of cardiac output through this nerve plexus, these data suggest that Nrg1 may play a critical role in establishing the cardiac nerve  ...  Interestingly, the nerve plexus appears to project from the atrium, through the AVC, then across the ventricle surface.  ... 
doi:10.1111/jcmm.13408 pmid:29265764 pmcid:PMC5824398 fatcat:5guylaarrbdl3dylzwycwoujla

Rare Primary Central Nervous System Tumors

Charlotte Dai Kubicky, Arjun Sahgal, Eric L. Chang, Simon S. Lo
2014 Rare Tumors  
There are close to 70,000 new cases of primary central nervous system tumors diagnosed annually in the United States.  ...  There is abundant literature on these commonly occurring tumors but data from the literature on infrequently encountered tumors such as atypical teratoid/rhabdoid tumor, choroid plexus carcinoma, ganglioglioma  ...  The exact mechanism by which hSNF5/INI1 mediates tumorigenesis is not fully understood.  ... 
doi:10.4081/rt.2014.5449 pmid:25276324 pmcid:PMC4178277 fatcat:yezistu2mnbyhgzadpbjzy5rci

Page 4961 of The Journal of Neuroscience Vol. 14, Issue 8 [page]

1994 The Journal of Neuroscience  
Blood vessels and choroid plexus were not sites of c-fos mRNA activation at either time point in this study.  ...  a humoral mechanism to trans- mit widespread influences on neuronal activity.  ... 

The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations

Martin M. Mortazavi, Christoph J. Griessenauer, Nimer Adeeb, Aman Deep, Reza Bavarsad Shahripour, Marios Loukas, Richard Isaiah Tubbs, R. Shane Tubbs
2013 Child's Nervous System  
Introduction The role of the choroid plexus in cerebrospinal fluid production has been identified for more than a century.  ...  Here, we review the macro-and microanatomical structure of the choroid plexus in addition to its function and embryology.  ...  In this series, 17 patients survived, and only 10 of them showed permanent relief of pressure, but only 6 of them had long-term survival.  ... 
doi:10.1007/s00381-013-2326-y pmid:24287511 fatcat:ouerdxaslvcbrccxafywzc3ady
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