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Neuroimaging, gut peptides and obesity: novel studies of the neurobiology of appetite

C Gibson, S Carnell, C Ochner, A Geliebter
2010 Journal of neuroendocrinology  
For example, neuroimaging studies have shown that exposure to appetising food cues results in preferential activation of hedonic regions of the human brain, and that obese individuals show greater activation  ...  Two studies have also combined hormones with neuroimaging of responses to food stimuli to examine the effect of long-term or genetic alterations of signalling on appetite and body weight in humans.  ... 
doi:10.1111/j.1365-2826.2010.02025.x pmid:20553371 pmcid:PMC3121301 fatcat:h2sbvbe4jve47j4kp5ag5x2cxm

The Brain Melanocortin System, Sympathetic Control, and Obesity Hypertension

Alexandre A. da Silva, Jussara M. do Carmo, Zhen Wang, John E. Hall
2014 Physiology  
In this review, we discuss the role of the brain melanocortin system in causing increased sympathetic activity in obesity and other forms of hypertension.  ...  In addition, we highlight potential mechanisms by which the brain melanocortin system modulates metabolic and cardiovascular functions.  ...  Scientist Development Grants to Alexandre A. da Silva and Jussara M. do Carmo.  ... 
doi:10.1152/physiol.00061.2013 pmid:24789984 pmcid:PMC4046815 fatcat:73p4w5tjgzdd5bvptvltroqlca

Page 2059 of None Vol. 62, Issue 2 [page]

2007 None  
Exposure to appetitive food stimuli markedly activates the human brain. Neuroimage 21: 1790- 1797, 2004. . Westerink BH. Brain microdialysis and its application for the study of animal behaviour.  ...  Another brain area that would be of interest to analyze is the prefrontal cortex, where significant abnormali- ties were documented in obese subjects presented with food- related stimuli (16).  ... 

Page 1212 of Psychological Abstracts Vol. 78, Issue 5 [page]

1991 Psychological Abstracts  
Cat PGO waves resemble waves that accompany alerting to intense or novel stimuli in human wake- fulness.  ...  (St Bartholomew's Hosp, Aca- demic Unit of Human Psychopharmacology, London, England) Mood and food: A psychopharmacological enquiry.  ... 

Get in My Belly: Food Preferences Trigger Approach and Avoidant Postural Asymmetries

Tad T. Brunyé, Jackie F. Hayes, Caroline R. Mahoney, Aaron L. Gardony, Holly A. Taylor, Robin B. Kanarek, Ramesh Balasubramaniam
2013 PLoS ONE  
The present study examined whether personal food-related preferences would activate approach and avoidance systems, modulating spontaneous postural sway toward and away from food items.  ...  Appetitive motivational states are fundamental neural and behavioral mechanisms underlying healthy and abnormal eating behavior, though their dynamic influence on food-related behavior is unknown.  ...  The appetitive system is responsible for approach-related behavior, and is activated in response to pleasant and rewarding stimuli.  ... 
doi:10.1371/journal.pone.0072432 pmid:24023618 pmcid:PMC3758305 fatcat:yikudtpypzczjis5ew536omp6e

Olfactory influences on appetite and satiety in humans

Martin R. Yeomans
2006 Physiology and Behavior  
Olfactory influences on appetite and satiety in humans. PHYSIOL BEHAV. 200X; 00(X): 000-000. Odor stimuli play a major role in perception of food flavor.  ...  Overall, these studies suggest that once an odor is experienced in a food-related context, that odor acquires the ability to modify both preparatory and satiety-related components of ingestion.  ...  Olfactory sensory-specific satiety has been shown to relate to activation of the orbitofrontal cortex in humans [43] , based on the observation that activation of the orbitofrontal area by banana odor  ... 
doi:10.1016/j.physbeh.2006.01.029 pmid:16545846 fatcat:pjrxpghwjfejnb4jgh2axlmrri

Olfactory influences on appetite and satiety in humans

Martin R. Yeomans
2006 Physiology and Behavior  
Olfactory influences on appetite and satiety in humans. PHYSIOL BEHAV. 200X; 00(X): 000-000. Odor stimuli play a major role in perception of food flavor.  ...  Overall, these studies suggest that once an odor is experienced in a food-related context, that odor acquires the ability to modify both preparatory and satiety-related components of ingestion.  ...  Olfactory sensory-specific satiety has been shown to relate to activation of the orbitofrontal cortex in humans [43] , based on the observation that activation of the orbitofrontal area by banana odor  ... 
doi:10.1016/j.physbeh.2006.04.010 pmid:16712883 fatcat:qdylmo2jr5cfrogyduv6cptsgy

Neurobiology of food addiction

Daniel M Blumenthal, Mark S Gold
2010 Current opinion in clinical nutrition and metabolic care  
of food addiction, freshly developed tools to better characterize pathological appetitive behaviors, and pharmacological treatments for obesity currently under development.  ...  This paper will review current, and proposed, definitions of substance use disorders, recent advances in our understanding of the physiology of addiction and food consumption, newly published evidence  ...  that the 'presentation of appetitive stimuli to fasting individuals increased self-reports of hunger and desire for food and increased whole brain metabolism to a similar (p 1251)' degree in both sexes  ... 
doi:10.1097/mco.0b013e32833ad4d4 pmid:20495452 fatcat:bwsq5atqzncyljkvfh6brjrmtq

Familiarity to a Feed Additive Modulates Its Effects on Brain Responses in Reward and Memory Regions in the Pig Model

David Val-Laillet, Paul Meurice, Caroline Clouard, Keiko Abe
2016 PLoS ONE  
The authors acknowledge Charles-Henri Malbert who initially developed the brain imaging protocol in pigs and part of the data processing method.  ...  Phodé Science participated to the discussion of the experimental protocol and results but had no role in decision to publish or preparation of the manuscript.  ...  study the brain responses to food stimuli [7, 8] , especially in neural networks involved in the characterization of food palatability, food motivation, reward expectancy and food control in the human  ... 
doi:10.1371/journal.pone.0162660 pmid:27610625 pmcid:PMC5017780 fatcat:fjz7ihlhpffinf7ch63u4hm5jy

Effects of Oro-Sensory Exposure on Satiation and Underlying Neurophysiological Mechanisms—What Do We Know So Far?

Marlou P. Lasschuijt, Kees de Graaf, Monica Mars
2021 Nutrients  
Oro-sensory exposure to food affects satiation by direct signaling via the brainstem to higher cortical regions involved in taste and reward, including the nucleus accumbens and the insula.  ...  Critical brain areas for satiation, such as the brainstem, should be studied more intensively to better understand the neurophysiological mechanisms underlying the process of satiation.  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/nu13051391 pmid:33919044 fatcat:56jsw4e3pvgkjmwuzjwa7hhlha

Aversive and Appetitive Events Evoke the Release of Corticotropin-Releasing Hormone and Bombesin-Like Peptides at the Central Nucleus of the Amygdala

Zul Merali, Judy McIntosh, Pamela Kent, David Michaud, Hymie Anisman
1998 Journal of Neuroscience  
There is wide agreement that corticotropin-releasing hormone (CRH) systems within the brain are activated by stressful stimuli.  ...  To date, however, the extent to which other stimuli increase the activity of these peptidergic systems has received little attention.  ...  There is wide agreement that corticotropin-releasing hormone (CRH) systems within the brain are activated by stressful stimuli.  ... 
doi:10.1523/jneurosci.18-12-04758.1998 pmid:9614249 fatcat:u5eaus3qajf33fe4unkdjkxgye

Eating habits and appetite control: a psychobiological perspective

Peter J. Rogers
1999 Proceedings of the Nutrition Society  
The physiological system controlling appetite appears to be adapted to solving the problem of an unevenness of food supply across time, and is fairly permissive in its response to undereating and overeating  ...  to faulty physiological control of appetite).  ...  Acknowledgement Preparation of this review was supported by the Biotechnology and Biological Sciences Research Council.  ... 
doi:10.1079/pns19990009 pmid:10343341 fatcat:putuzdis5bclraxsaj4o2nic34

Functional brain imaging and its application to uncover mechanisms driving food intake in humans

Claudio L. Lafortuna, Sarah A. Tabozzi, Rizzo Giovanna
2014 Journal of Biomedical Graphics and Computing  
and the conscious experience of pleasure and reward concurring to the control of food intake.  ...  activity.  ...  "Invecchiamento" and by project "Platform for International Collaborative Knowledge on Food Improvement Based on Ecological Resources (PICKFIBER)", funded by INTERREG IVC Programme, and partially appeared  ... 
doi:10.5430/jbgc.v4n3p10 fatcat:zhoffhlyajcj3oek7v2os3xtia

Dopamine and Food Addiction: Lexicon Badly Needed

John D. Salamone, Mercè Correa
2013 Biological Psychiatry  
Nevertheless, the use of the term "addiction" to describe pathological aspects of food intake in humans remains controversial, and even among those who affirm the validity of the concept, there is considerable  ...  An examination of the literature on food addiction indicates that mesolimbic and nigrostriatal dopamine systems often are cited as mechanisms that contribute to the establishment of food addiction.  ...  Salamone is supported by grants from the National Institute of Mental Health (MH078023), the National Institute of Drug Abuse (U01DA016194), Pfizer and Hoffman La Roche, and has received an honorarium  ... 
doi:10.1016/j.biopsych.2012.09.027 pmid:23177385 pmcid:PMC4450088 fatcat:adrfussetrhpfat7vol3yaj2wq

The determinants of food choice

Gareth Leng, Roger A. H. Adan, Michele Belot, Jeffrey M. Brunstrom, Kees de Graaf, Suzanne L. Dickson, Todd Hare, Silvia Maier, John Menzies, Hubert Preissl, Lucia A. Reisch, Peter J. Rogers (+1 others)
2016 Proceedings of the Nutrition Society  
understanding of the determinants of food choice.  ...  In addition, our choices are influenced by an array of physiological mechanisms, including signals to the brain from the gastrointestinal tract and adipose tissue, which affect not only our hunger and  ...  Conflict of Interest Peter Rogers has received funding for research on food and behaviour from industry, including from Sugar Nutrition UK.  ... 
doi:10.1017/s002966511600286x pmid:27903310 fatcat:2judr3iukzadbiulhcf5wveosu
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