Filters








71 Hits in 3.7 sec

Exposome informatics: considerations for the design of future biomedical research information systems

Fernando Martin Sanchez, Kathleen Gray, Riccardo Bellazzi, Guillermo Lopez-Campos
2014 JAMIA Journal of the American Medical Informatics Association  
In comparison, future information systems for research will have to use new methods to process the flow and mix of data that will generate the coming wave of biomedical information and insights.  ...  types will require changes in biomedical informatics methods. the information and its consequent integration into an information system.  ... 
doi:10.1136/amiajnl-2013-001772 pmid:24186958 pmcid:PMC3994854 fatcat:wtlvwkwpn5gktgb42aynt55vhu

Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health

Arjun K. Manrai, Yuxia Cui, Pierre R. Bushel, Molly Hall, Spyros Karakitsios, Carolyn J. Mattingly, Marylyn Ritchie, Charles Schmitt, Denis A. Sarigiannis, Duncan C. Thomas, David Wishart, David M. Balshaw (+1 others)
2017 Annual Review of Public Health  
See credit lines of images or other third-party material in this article for license information. as human genomics research.  ...  biomedical research.  ...  and who may not have anticipated the future application of their work to the exposome concept.  ... 
doi:10.1146/annurev-publhealth-082516-012737 pmid:28068484 pmcid:PMC5774331 fatcat:ystlcd6nhfhcpolp2ca22t4ntu

Research Strategies for Biomedical and Health Informatics

Casimir Kulikowski, Suzanne Bakken, Simon de Lusignan, Michio Kimura, Sabine Koch, John Mantas, Victor Maojo, Michael Marschollek, Fernando Martin-Sanchez, Anne Moen, Hyeoun-Ae Park, Indra Neil Sarkar (+3 others)
2017 Methods of Information in Medicine  
What could be consequences of change for research and for education?  ...  Background: Medical informatics, or biomedical and health informatics (BMHI), has become an established scientific discipline.  ...  Casimir Kulikowski: Interpreting heterogeneous models of biomedical information for scientific inquiry and experimental design is needed across the spectrum of health and disease [43] , based on neuroscience  ... 
doi:10.3414/me16-01-0125 pmid:29589365 pmcid:PMC5388922 fatcat:bu2ml6b7f5byrn2ghxcvcckib4

Added Value from Secondary Use of Person Generated Health Data in Consumer Health Informatics

P.-Y. Hsueh, Y.-K. Cheung, S. Dey, K. K. Kim, F. J. Martin-Sanchez, S. K. Petersen, T. Wetter
2017 IMIA Yearbook of Medical Informatics  
exposure data in an integrated context with clinical and omics-data for biomedical research.  ...  of PGHD from patient-held sensors to inform cancer care; (3) fitting situational use of PGHD to evaluate personal informatics tools in adaptive concurrent trials; (4) making sense of environment risk  ...  .), but PGHD offers a unique opportunity for biomedical research [84] .  ... 
doi:10.1055/s-0037-1606534 fatcat:2ryn4yrz45fo7jh4encuzjnena

Added Value from Secondary Use of Person Generated Health Data in Consumer Health Informatics

P.-Y. Hsueh, Y.-K. Cheung, S. Dey, K. K. Kim, F. J. Martin-Sanchez, S. K. Petersen, T. Wetter
2017 IMIA Yearbook of Medical Informatics  
exposure data in an integrated context with clinical and omics-data for biomedical research.  ...  of PGHD from patient-held sensors to inform cancer care; (3) fitting situational use of PGHD to evaluate personal informatics tools in adaptive concurrent trials; (4) making sense of environment risk  ...  .), but PGHD offers a unique opportunity for biomedical research [84] .  ... 
doi:10.15265/iy-2017-009 pmid:28480472 pmcid:PMC6239245 fatcat:5qgn2enthfakffcfmwe3nmx5bm

Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document

Ioana Agache, Rachel Miller, James E. Gern, Peter W. Hellings, Marek Jutel, Antonella Muraro, Wanda Phipatanakul, Santiago Quirce, David Peden
2018 Allergy. European Journal of Allergy and Clinical Immunology  
Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the life span.  ...  and the unmet needs on the role of the exposome in allergic diseases and asthma.  ...  Thus, a holistic and comprehensive understanding of the exposome in the built environment is needed to design a framework for informing design and control of buildings in a manner that promotes human health  ... 
doi:10.1111/all.13690 pmid:30515837 fatcat:l7m5e3embjdafd7mqe7xnktzmq

GDPR Compliance Challenges for Interoperable Health Information Exchanges (HIEs) and Trustworthy Research Environments (TREs)

Ed Conley, Matthias Pocs
2018 European Journal for Biomedical Informatics  
Conclusion: We recognise the need for wider implementation of rigorous interoperability standards concerning privacy and security management.  ...  Comprehensive model-based approaches to information management will be fundamental to guaranteeing security and privacy in challenging areas such as ethical use of artificial intelligence in medicine.  ...  Acknowledgement The authors gratefully acknowledge project funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 727301.  ... 
doi:10.24105/ejbi.2018.14.3.7 fatcat:ohbj6hj4erbl3cyinni56mlw5u

Integrated Biomedical System

Darrell O. Ricke, James Harper, Anna Shcherbina, Nelson Chiu, Tara Boettcher
2018 F1000Research  
of proteins, population levels for thousands of microbial species, quantitative imaging data, and more -all on the same individual.  ...  Capabilities for generating and storing large amounts of data Background: relevant to individual health and performance are rapidly evolving and have the potential to accelerate progress toward quantitative  ...  Acknowledgements The authors would like to acknowledge Carl Ricke, Freelance Illustrator at Wanderbots, for graphic artwork.  ... 
doi:10.12688/f1000research.13601.1 fatcat:b7hrwxujkzg2bca6ompkxpqg5e

Advances in Sharing Multi-sourced Health Data on Decision Support Science 2016-2017

Nick Anderson, Prabhu Shankar
2018 IMIA Yearbook of Medical Informatics  
Objective: Evaluate key advances and challenges of accessing, sharing, and managing data from multiple sources for development and implementation of Clinical Decision Support (CDS) systems in 2016-2017  ...  However, the availability of patient-related "Big Data" sources from genomics and mobile health, expanded privacy considerations, applications of service-based computational techniques and tools, the emergence  ...  Acknowledgments This work was supported in part by NCATS grant UL1TR001860 from the National Institutes of Health (USA).  ... 
doi:10.1055/s-0038-1641215 pmid:30157504 fatcat:4vekturoffhp7jdvbc7osqynyu

Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

Timothy H Ciesielski, Sarah A Pendergrass, Marquitta J White, Nuri Kodaman, Rafal S Sobota, Minjun Huang, Jacquelaine Bartlett, Jing Li, Qinxin Pan, Jiang Gui, Scott B Selleck, Christopher I Amos (+3 others)
2014 BioData Mining  
for directing future research.  ...  The Diverse Convergent Evidence approach (DiCE) we propose integrates information from multiple sources (omics, informatics, and laboratory experiments) to estimate the strength of the available corroborating  ...  For RS: This work was supported by Public Health Service award T32 GM07347 from the National Institute of General Medical Studies for the Vanderbilt Medical-Scientist Training Program.  ... 
doi:10.1186/1756-0381-7-10 pmid:25071867 pmcid:PMC4112852 fatcat:zyg34ehxtzenxnv6nrpq4bldhm

Health-Enabling and Ambient Assistive Technologies: Past, Present, Future

K.-H. Wolf, R. Haux, S. Koch, N.H. Lovell, M. Marschollek, N. Nakashima
2016 IMIA Yearbook of Medical Informatics  
Background: During the last decades, health-enabling and ambient assistive technologies became of considerable relevance for new informatics-based forms of diagnosis, prevention, and therapy.  ...  Methods: Systematic review of all original articles with research focus in all volumes of the IMIA Yearbook of Medical Informatics.  ...  Acknowledgements We cordially want to thank the editors of the Yearbook, Marie-Christine Jaulent, Christoph U.  ... 
doi:10.15265/iys-2016-s008 pmid:27362588 pmcid:PMC5171510 fatcat:nxa47bne5be2fn4j5qc6arqrka

Is it Time for Cognitive Bioinformatics?

Lisitsa Andrey, Stewart Elizabeth, Kolker Eugene
2015 Journal of Data Mining in Genomics & Proteomics  
The unbalanced nature of accumulating information along with some challenges poses currently intractable problems for researchers.  ...  Deluge of Life Sciences Big Data Modern molecular biology studies the function and interactions of biological molecules, processes and systems.  ...  In medicine, in addition to this issue, there is a considerable need for a physician who can turn biomedical information into life-changing decisions.  ... 
doi:10.4172/2153-0602.1000173 fatcat:34cq27u4krda7ga2ntaxifglw4

Clinical Decision Support: a 25 Year Retrospective and a 25 Year Vision

D. F. Sittig, A. Wright, B. Middleton
2016 IMIA Yearbook of Medical Informatics  
explosion of methods analyzing and inferring from clinical data, evolution of information technologies and architectures to facilitate the broad application of CDS, improvement of methods to implement  ...  Method: Informal review of the medical literature with iterative review and discussion among the authors to arrive at six axes (data, knowledge, inference, architecture and technology, implementation and  ...  Nevertheless, progress was being made in the design and implementation of CDS systems at some leading sites motivated by academic interest in research and development, desire for higher quality care or  ... 
doi:10.15265/iys-2016-s034 pmid:27488402 pmcid:PMC5171504 fatcat:ry2ppqarznbgtdfzzw3kfaoiw4

Translational bioinformatics in the era of real-time biomedical, health care and wellness data streams

Khader Shameer, Marcus A. Badgeley, Riccardo Miotto, Benjamin S. Glicksberg, Joseph W. Morgan, Joel T. Dudley
2016 Briefings in Bioinformatics  
The accessibility and clinical utility of such Khader Shameer is a senior biomedical and health care informatics scientist in Dr Joel Dudley's laboratory and the Harris Center for Precision Wellness of  ...  He obtained his MS in on the development and use of translational informatics approaches to address critical challenges in systems medicine.  ...  /genomics), of Mount Sinai Health System for infrastructural support.  ... 
doi:10.1093/bib/bbv118 pmid:26876889 pmcid:PMC5221424 fatcat:aqurlfusq5hslpabllsfmygk6m

The Future of Cardiovascular Epidemiology: Table

Ramachandran S. Vasan, Emelia J. Benjamin
2016 Circulation  
as a sine quo non for all future epidemiological investigations.  ...  Additionally, the notion that a great deal of epidemiological research results in false-positive findings has gained momentum, 7 thereby raising the bar for both study quality and the necessity for replication  ...  A recent Institute of Medicine report noted that "critical to the implementation of big data science is the need for highquality biomedical informatics, bioinformatics, and mathematics and biostatistical  ... 
doi:10.1161/circulationaha.116.023528 pmid:27324358 pmcid:PMC4974092 fatcat:zeaz4ivjkncovkjxzbkldhevha
« Previous Showing results 1 — 15 out of 71 results