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Exploring the structure-property relations of thin-walled, 2D extruded lattices using neural networks [article]

Junyan He, Shashank Kushwaha, Diab Abueidda, Iwona Jasiuk
2022 arXiv   pre-print
This paper investigates the structure-property relations of thin-walled lattices under dynamic longitudinal compression, characterized by their cross-sections and heights.  ...  Using an autoencoder, we encoded the cross-sectional images of the lattices into latent design feature vectors, which were supplied to the neural network model to generate predictions.  ...  J.) acknowledges the support of the Army Research Office contract (No. W 911NF-18-2-0067) and the National Science Foundation grant (MOMS-1926353).  ... 
arXiv:2205.06761v1 fatcat:fcgpp5r2pzb2haen2zapg4qezm

Discovery of Cellular Unit Cells With High Natural Frequency and Energy Absorption Capabilities by an Inverse Machine Learning Framework

Adithya Challapalli, John Konlan, Dhrumil Patel, Guoqiang Li
2021 Frontiers in Mechanical Engineering  
In this study, machine learning regression and Generative Neural Networks (GANs) were used to form an inverse design framework.  ...  In addition, because of the less amount of materials used in cellular structures, the energy absorption capability usually decreases such as under impact loading.  ...  Inverse Design of Porous Materials Using Artificial Neural Networks. Sci.  ... 
doi:10.3389/fmech.2021.779098 fatcat:gsy2aj34uzhrxhtio5krnqkemi

3D Bioprinting for Organ Regeneration

Haitao Cui, Margaret Nowicki, John P. Fisher, Lijie Grace Zhang
2016 Advanced Healthcare Materials  
We focus on the applications of this technology for engineering living organs, focusing more specifically on vasculature, neural networks, the heart and liver.  ...  properties, and biological functions of target tissues and organs.  ...  Acknowledgements This work is supported by NIH Director's New Innovator Award 1DP2EB020549-01, NSF BME program grant # 1510561, NSF MME program grant # 1642186 and March of Dimes Foundation's Gene Discovery  ... 
doi:10.1002/adhm.201601118 pmid:27995751 pmcid:PMC5313259 fatcat:5zeul6s3fvft3ew4iyicifyaqa

Progress of 3D Bioprinting in Organ Manufacturing

Dabin Song, Yukun Xu, Siyu Liu, Liang Wen, Xiaohong Wang
2021 Polymers  
The unique advantages of 3D bioprinting technologies for organ manufacturing have improved the traditional medical level significantly.  ...  The important characteristics of the printable polymers and the typical 3D bioprinting technologies for several complex bioartificial organs, such as the heart, liver, nerve, and skin, are introduced.  ...  from the G-code (U); (V) A highdefinition image of the septal wall between ventricles (W) Showing reproduction of the square-lattice infill [173].  ... 
doi:10.3390/polym13183178 pmid:34578079 fatcat:yrwgihjkknctnikrwezk7linyq

Multi-morphology lattices lead to improved plastic energy absorption

Ryan Alberdi, Remi Dingreville, Joshua Robbins, Timothy Walsh, Benjamin C. White, Bradley Jared, Brad L. Boyce
2020 Materials & design  
Such multi-morphology lattices can harness the distinct mechanical properties of different unit cells while being composed out of a single base material.  ...  A rational design approach was developed to explore the design space of these lattices, inspiring a non-intuitive design which was evaluated alongside designs based on mixture rules.  ...  Acknowledgements This work was performed, in part, at the Center for Integrated Nanotechnologies, an Office of  ... 
doi:10.1016/j.matdes.2020.108883 fatcat:af4t5unikrcnngjhc6xb62vuse

MRS News

2001 MRS bulletin  
Domain patterns also proved to be the key in the ferroelectric thin films that have lattice mismatch with the substrate.  ...  Some evidence indicated that non-180°d omain walls show some movement during switching, although the majority of the domain walls are pinned by the substrate in ferroelectric thin films.  ...  Domain patterns also proved to be the key in ferroelectric thin films that have lattice mismatch with the substrate.  ... 
doi:10.1557/mrs2001.46 fatcat:zybxwwyda5bcjp3iomojgi3p3u

3D graphene-containing structures for tissue engineering

J. Li, X. Liu, J.M. Crook, G.G. Wallace
2019 Materials Today Chemistry  
structures (3DGCSs) are especially endowed with useable features relating to physicochemical properties within the hierarchical architectures.  ...  harvesting, environmental protection and healthcare. 3D graphene containing structures (3DGCSs) are especially endowed with useable features relating to physico-chemical properties within the hierarchical  ...  Acknowledgements The authors gratefully acknowledge the Australian Research Council (ARC) Centre of Excellence Scheme for provision of funding (CE140100012) and support from the Australian National  ... 
doi:10.1016/j.mtchem.2019.100199 fatcat:bbpnw26mhvhl7avgdl2eyrjs5i

Rational Design of Microfabricated Electroconductive Hydrogels for Biomedical Applications

Brian W. Walker, Roberto Portillo Lara, Emad Mogadam, Chu Hsiang Yu, William Kimball, Nasim Annabi
2019 Progress in polymer science  
ECHs combine several advantageous properties of inherently conductive materials with the highly tunable physical and biochemical properties of hydrogels.  ...  In addition, smart ECHs with controlled structures and healing properties have also been engineered into devices with prolonged half-lives and increased durability.  ...  A. acknowledges the support from the American Heart Association (AHA, 16SDG31280010), and National Institutes of Health (R01-EB023052; R01HL140618).  ... 
doi:10.1016/j.progpolymsci.2019.02.007 pmid:32831422 pmcid:PMC7441850 fatcat:6m3m67rfijc5zhzenzdl5gub7m

Scalably nanomanufactured atomically thin materials based wearable health sensors

Ruifang Zhang, Jing Jiang, Wenzhuo Wu
2021 Small Structures  
[20] [21] and 2) the design and engineering of rigid inorganic materials into flexible/ stretchable structures. [22, 23] [26] [27] [28] [29] The markets for 2D materials and related applications are forecasted  ...  to grow from <$100 m in 2020 to %$700 m by 2031. [30] The atomically thin thickness and the ultrahigh surface ratio of 2D materials endow the superior mechanical deformability and robustness, extreme  ...  However, the structure seemed to be partially collapsing, probably due to pore-wall thinning, thus decreasing the porosity.  ... 
doi:10.1002/sstr.202100120 fatcat:ll64rmm4qvfc5mjjnsilnaj2ie

Recent progress in extrusion 3D bioprinting of hydrogel biomaterials for tissue regeneration: a comprehensive review with a focus on advanced fabrication techniques

Mohsen Askari, Moqaddaseh Afzali Naniz, Monireh Kouhi, Azadeh Saberi, Ali Zolfagharian, Mahdi Bodaghi
2020 Biomaterials Science  
Thanks to the complexity of tissues, various bioprinting methods are exploited to figure...  ...  Over the last decade, 3D bioprinting has received immense attention from research communities for developing functional tissues.  ...  Thin endothelialized vessel walls were created by the incorporation of biocompatible crosslinkers.  ... 
doi:10.1039/d0bm00973c pmid:33185203 fatcat:4uk6foagxbduhinqplhimwcexq

Expanding and optimizing 3D bioprinting capabilities using complementary network bioinks

Liliang Ouyang, James P K Armstrong, Yiyang Lin, Jonathan P Wojciechowski, Charlotte Lee-Reeves, Daniel Hachim, Kun Zhou, Jason A Burdick, Molly M Stevens
2020 Science Advances  
A range of complex and heterogeneous structures are printed, including soft hydrogel constructs supporting the 3D culture of astrocytes.  ...  This strategy enables the effective printing of biomaterials that would typically not meet printing requirements, with instrument parameters and structural output largely independent of the base biomaterial  ...  Li for help with the schematic drawing in Fig. 1 , S. C. Skaalure for help with materials preparation, S. Treumuth for help with cell isolation and culture, T. Benge for help with ALP assay, G.  ... 
doi:10.1126/sciadv.abc5529 pmid:32948593 pmcid:PMC7500929 fatcat:bkj25x4ez5gjtmxt5dtu3uraqa

Engineering Organoid Vascularization

Sergei Grebenyuk, Adrian Ranga
2019 Frontiers in Bioengineering and Biotechnology  
Over the last decade, the advent of organoids has demonstrated that cells have the ability to reorganize into complex tissue-specific structures given minimal inductive factors.  ...  However, a major limitation in achieving truly in vivo-like functionality has been the lack of structured organization and reasonable tissue size.  ...  AUTHOR CONTRIBUTIONS All authors have contributed to writing, editing and revising of the manuscript, and have approved it for publication.  ... 
doi:10.3389/fbioe.2019.00039 pmid:30941347 pmcid:PMC6433749 fatcat:4fxy6keiwne4xnilliqvta4o5u

Spatially and temporally controlled hydrogels for tissue engineering

Jeroen Leijten, Jungmok Seo, Kan Yue, Grissel Trujillo-de Santiago, Ali Tamayol, Guillermo U. Ruiz-Esparza, Su Ryon Shin, Roholah Sharifi, Iman Noshadi, Mario Moisés Álvarez, Yu Shrike Zhang, Ali Khademhosseini
2017 Materials science & engineering. R, Reports  
Thus, the cellular responses to the physical and chemical properties of hydrogel surfaces are intimately related to functionalities that are important in the context of tissue engineering, such as implant  ...  , as well as the practical uses of hydrogels as surface modifiers. 2.1.1.  ...  cell culture models for in vitro formation of neural networks.  ... 
doi:10.1016/j.mser.2017.07.001 pmid:29200661 pmcid:PMC5708586 fatcat:l45vlsq5dbcilpsw2vbggawvp4

From Shape to Function: The Next Step in Bioprinting

Riccardo Levato, Tomasz Jungst, Ruben G. Scheuring, Torsten Blunk, Juergen Groll, Jos Malda
2020 Advanced Materials  
However, recent developments have now resulted in the availability of a plethora of bioinks, new printing approaches, and the technological advancement of established techniques.  ...  In 2013, the "biofabrication window" was introduced to reflect the processing challenge for the fields of biofabrication and bioprinting.  ...  structural and mechanical properties of the polymer network.  ... 
doi:10.1002/adma.201906423 pmid:32045053 fatcat:hpwjy6takvfxvcp5c3gjy4prsu

Flexible and Stretchable Bioelectronics

Chandani Chitrakar, Eric Hedrick, Lauren Adegoke, Melanie Ecker
2022 Materials  
Ultimately, these bioelectronic devices can be used for wide range of applications from skin bioelectronics and biosensing devices, to neural implants for diagnostic or therapeutic purposes.  ...  Bioelectronics are also used to monitor the biological cues to assess the homeostasis of the body. In a way, they bridge the gap between drug-based interventions and medical devices.  ...  Data Availability Statement: The study did not report any data. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/ma15051664 pmid:35268893 pmcid:PMC8911085 fatcat:bbxb56cpqrbtngyncs4alb6d2e
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