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Exploring the current practices, costs and benefits of FAIR Implementation in pharmaceutical Research and Development: A Qualitative Interview Study

Ebtisam Alharbi, Rigina Skeva, Nick Juty, Caroline Jay, Carole Goble
2021 Data Intelligence  
To date, little scientific evidence exists about how FAIR is currently implemented in practice, what its associated costs and benefits are, and how decisions are made about the retrospective FAIRification  ...  Research and development (R&D) in the pharmaceutical industry is becoming increasingly data driven, but managing its data assets according to FAIR principles remains costly and challenging.  ...  Goble and N. Juty acknowledge the FAIRplus project (IMI2 Joint Undertaking under grant agreement No 802750). The EPSRC supported C. Jay in this work under EP/S021779/1. E.  ... 
doi:10.1162/dint_a_00109 fatcat:5enj5pqgdvab3bisw7f76vck54

How Can We Optimize the Value Assessment and Appraisal of Orphan Drugs for Reimbursement Purposes? A Qualitative Interview Study Across European Countries

Alessandra Blonda, Yvonne Denier, Isabelle Huys, Pawel Kawalec, Steven Simoens
2022 Frontiers in Pharmacology  
In addition, the study identified a number of "contextual" determinants (e.g., bias, perverse effects of the orphan drug legislation, and an inadequate consideration of the opportunity cost), which may  ...  19 different countries were included in a qualitative survey, followed by in-depth semi-structured interviews.  ...  In addition, they would like to thank Valérie Haers, Laura Elpers, Nele Thyvelen and Julie van Tricht for their diligent transcription of the interviews.  ... 
doi:10.3389/fphar.2022.902150 pmid:35928274 pmcid:PMC9343828 doaj:6798b000a1b5411eafd595147812ea28 fatcat:7yrx2pdk55cwjhqgbehkq3kalu

"All about the money?" A qualitative interview study examining organizational- and system-level characteristics that promote or hinder shared decision-making in cancer care in the United States

Isabelle Scholl, Sarah Kobrin, Glyn Elwyn
2020 Implementation Science  
The aim of the study was to explore how organizational and health system characteristics affect SDM implementation in US cancer care.  ...  The dominant theme in the data obtained was that concerns regarding a lack of revenue generation, or indeed, the likely loss of revenue, were a major barrier preventing implementation of SDM.  ...  Acknowledgements We are grateful to all participants for their contribution to the study. We also thank Allison LaRussa for reviewing and copy-editing the transcripts.  ... 
doi:10.1186/s13012-020-01042-7 pmid:32957962 pmcid:PMC7507661 fatcat:quck7jugjral3iwwojgty4innu

Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic

Amy Fuller, Jennie Hancox, Kavita Vedhara, Tim Card, Christian Mallen, Jonathan S. Nguyen Van-Tam, Abhishek Abhishek, Latika Gupta
2022 PLoS ONE  
Methods Recruiting through national patient charities and a local hospital, participants were invited to take part in an in-depth, one-to-one, semi-structured interview with a trained qualitative researcher  ...  Addressing vaccine benefits and safety for IMID-patients in clinical practice, direct invitation, and public-health messaging highlighting immunosuppression as key vaccination-eligibility criteria may  ...  Acknowledgments We would like to extend our thanks to the following charities who supported with recruitment: National Rheumatoid Arthritis Society, National Ankylosing Spondylitis Society, Crohns and  ... 
doi:10.1371/journal.pone.0267769 pmid:36084032 pmcid:PMC9462800 fatcat:hvzum7coofgg5jeqoqp6v6dbme

Human Resource Management Challenges to Develop Pharmaceutical Industry: Evidence from Developing Countries

Jafar Babapour, Arian Gholipourb, Gholamhossein Mehralian
2018 Iranian journal of pharmaceutical research  
In this study, an attempt was made to explore the challenges of human resource management practices surrounding pharmaceutical firms in Iran, as a developing country.  ...  To answer the research question, a qualitative descriptive study using thematic analysis was performed through 22 semi-structured interviews with the key informants of Iranian pharmaceutical industry.  ...  Acknowledgment The authors would like to disclose their sincere thanks to all the interviewees from the Iranian pharmaceutical industry who participated in this study.  ... 
pmid:31011355 pmcid:PMC6447866 fatcat:vfzuo4lblraofhl4vmq2ex4oxu

Nurse prescribing in primary care: a metasynthesis of the literature

Dilyse Nuttall
2017 Primary Health Care Research and Development  
Although a range of quantitative and qualitative studies have been undertaken, which aimed to explore the influences on prescribing, few have used a research methodology that supports the in-depth exploration  ...  Aim The aim of this metasynthesis was to develop an understanding of the existing theoretical perspectives around nurse prescribing and to identify any gaps in knowledge, which would support further research  ...  Financial Support This metasynthesis was undertaken as part of MPhil/PhD studies that were partially funded by the Continuing Professional Development monies from the Faculty of Health and Wellbeing, University  ... 
doi:10.1017/s1463423617000500 pmid:28786368 fatcat:afyhuexlubb53o2avelsxmijsa

Evaluating the "return on patient engagement initiatives" in medicines research and development: A literature review

Lidewij Eva Vat, Teresa Finlay, Tjerk Jan Schuitmaker‐Warnaar, Nick Fahy, Paul Robinson, Mathieu Boudes, Ana Diaz, Elisa Ferrer, Virginie Hivert, Gabor Purman, Marie‐Laure Kürzinger, Robert A. Kroes (+2 others)
2019 Health Expectations  
Several quantitative and qualitative methods were found for the evaluation of benefits and costs of patient engagement.  ...  This paper is focused on ways to evaluate patient engagement at three decision-making points in the medicines research and development process: research priority setting, clinical trial design and early  ...  | Benefits, costs and challenges for research and development A total of 18 benefits and five costs of patient engagement at three R&D decision-making points were identified.  ... 
doi:10.1111/hex.12951 pmid:31489988 fatcat:xwzdewvrzjeujagafafowqklfq

Exploring Business Transformation: The Challenges of Developing a Benefits Realization Capability

Colin Ashurst, Julie Hodges
2010 Journal of Change Management  
Firstly, the qualitative empirical study has provided an insight into the current benefits realization capability of organizations and the challenges they face in further developing this capability. 21  ...  As a first stage we have explored the current benefits realization capability of organizations and particularly the challenges they face in further developing this capability.  ... 
doi:10.1080/14697011003795685 fatcat:q43ticqgzfcz5d7r66phykcihi

Contributing barriers to corporate social and environmental responsibility practices in a developing country

Md Moazzem Hossain, Manzurul Alam, Angela Hecimovic, Mohammad Alamgir Hossain, Aklema Choudhury Lema
2016 Sustainability Accounting, Management and Policy Journal  
In particular, this study focuses on non-managerial stakeholders' perceptions of the barriers to CSER practices in a developing country context.  ...  Originality/Value -This paper is one of the few engagement-based studies to explore the non-managerial stakeholders' views on CSER in a developing country context.  ...  This qualitative study forms a basis for future research on CSER practice and can be validated through further empirical testing in different developing country contexts.  ... 
doi:10.1108/sampj-09-2014-0056 fatcat:e2khhillb5barot2w6j4ggcd2u

SAPC Annual Conference 2010 Abstracts, 7–9 July 2010, University of East Anglia, UK

2010 Primary Health Care Research and Development  
For subjects who feel depressed and are open to help, GPs can play an important motivating role to accept the intervention.  ...  In practice, these targets are often unmet. A qualitative study has been undertaken to explore patient and staff's views and experiences of the current management of TIA.  ...  Qualitative analysis of interviews with residents and their families is currently underway to explore these findings in more depth.  ... 
doi:10.1017/s1463423610000447 fatcat:eihc57jkdrg7jjifyp376quxhe

Community involvement and development

David Katamba, Cedric Marvin Nkiko, Charles Tushabomwe Kazooba, Imelda Kemeza, Sulayman Babiiha Mpisi
2014 International Journal of Social Economics  
Research limitations/implications -The case study (Uganda Baati Ltd, -UBL) that informed this research is a subsidiary company of a multinational, SAFAL Group.  ...  Data collection was by semi-structured interviews with CSR managers of the studied company, plus non-participant observation of CSR activities and projects.  ...  Direct observations were made in the natural setting by the researchers, providing a source of evidence to support the interviews (a view exemplified in Yin's, 2004 case study of Middletown), which offered  ... 
doi:10.1108/ijse-05-2013-0110 fatcat:jk6kkzrhufb2tjvze2wtstwlfq

Future Development Through the Past: Pathology of the Financing Dimension of Iran's Health Transformation Plan

Leila Doshmangir, Behzad Najafi, Hakimeh Mostafavi, Esmaeil Moshiri
2020 ClinicoEconomics and Outcomes Research  
So, developing or continuing to implement a plan in the health system depends on the current and future global and local economic trends.  ...  Face-to-face interviews were conducted with health policymakers at different levels of the health system, health researchers, health insurance officers, and faculty members.  ...  Author Contributions All authors made substantial contributions to conception and design of the study, acquisition of data, analysis and interpretation of data; took part in drafting the article or revising  ... 
doi:10.2147/ceor.s253601 pmid:32753916 pmcid:PMC7354001 fatcat:utsjmpvxmrgxbdwrsusyjrkpde

Integrating evidence on patient preferences in healthcare policy decisions: protocol of the patient-VIP study

Carmen D Dirksen, Cecile MA Utens, Manuela A Joore, Teus A van Barneveld, Bert Boer, Dunja HH Dreesens, Hans van Laarhoven, Cees Smit, Anne M Stiggelbout, Trudy van der Weijden
2013 Implementation Science  
The second sub-study is a qualitative study to explore the opinions of stakeholders with regard to the possibilities for integrating evidence on patient preferences in the process of healthcare decision-making  ...  The third sub-study is the development of a decision framework for research on patient preferences.  ...  Acknowledgements The study is financed by a grant from the Netherlands Organisation for Health Research  ... 
doi:10.1186/1748-5908-8-64 pmid:23758977 pmcid:PMC3686695 fatcat:i6ukioj4rnd6ph5jcizgstlzym

Developing a framework for responsible downsizing through best fit: the importance of regulatory, procedural, communication and employment responsibilities

Christopher J. McLachlan
2021 International Journal of Human Resource Management  
The paper draws on HR theories of best practice and best fit to explore the phenomenon of responsible downsizing, as a dominant focus in extant literature is the identification of 'responsible' best practices  ...  While there is value in adopting best practices the paper argues that greater attention should be paid to how organisational, societal and institutional contexts shape their implementation.  ...  manufacturer in the uK Qualitative X X X snell and gekara (2020) case study of ford plant closure in australia Qualitative X X X mclachlan et al. (2021) case study of restructuring a steel firm in the  ... 
doi:10.1080/09585192.2021.1958248 fatcat:xc6llchaijcrpcxkfrhbrkncu4

Business Development Capability: Insights from the Biotechnology Industry

Valeria Lorenzi, Hans Eibe Sørensen
2014 Symphonya Emerging Issues in Management  
The aim of this paper is to explore the organization of business development on the basis of existing empirical literature and three case studies from the biotechnology industry.  ...  Such business development activities are found and refined in the biotechnology industry, but have received remarkable little attention in the academic literature.  ...  Finally, although the research results provide a useful framework for organizing and implementing a Business Development function within a firm, the study is qualitative in nature and thus calls for further  ... 
doi:10.4468/2014.2.05lorenzi.sorensen fatcat:dlcbcmi5e5gitbidfqjfm3ggwa
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