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Systematic Review of Functional MRI Applications for Psychiatric Disease Subtyping

Lucas Miranda, Riya Paul, Benno Pütz, Nikolaos Koutsouleris, Bertram Müller-Myhsok
2021 Frontiers in Psychiatry  
Major depression disorder and schizophrenia were the two most frequently studied pathologies (35% and 30% of the retrieved studies, respectively), followed by ADHD (15%), psychosis as a whole (10%), autism  ...  , four used it to interpret clusters derived from biomarker data other than fMRI itself, and 11 applied clustering techniques involving fMRI directly.  ...  NMF compresses the feature space into a user-defined number of factors by decomposing the data into two nonnegative matrices: a basis matrix (called dictionary) with factors as columns, and a factor-loading  ... 
doi:10.3389/fpsyt.2021.665536 pmid:34744805 pmcid:PMC8569315 fatcat:jmcxqcdzjba5bhvcpcrj2zvv3i

Brain Connectivity Analysis: A Short Survey

E. W. Lang, A. M. Tomé, I. R. Keck, J. M. Górriz-Sáez, C. G. Puntonet
2012 Computational Intelligence and Neuroscience  
Future studies have to bridge the gap between anatomical neuronal connections and related functional or effective connectivities.  ...  This short survey the reviews recent literature on brain connectivity studies. It encompasses all forms of static and dynamic connectivity whether anatomical, functional, or effective.  ...  Acknowledgments Support by the DAAD-FCT, the BFHZ-CCUFB, and the GENIL-SPR project at CITIC-UGR is gratefully acknowledged.  ... 
doi:10.1155/2012/412512 pmid:23097663 pmcid:PMC3477528 fatcat:zlwqwx6n7feefdrfx5pnhhbmhe

Investigating microstructural variation in the human hippocampus using non-negative matrix factorization

Raihaan Patel, Christopher J. Steele, Anthony Chen, Sejal Patel, Gabriel A. Devenyi, Jürgen Germann, Christine L. Tardif, M. Mallar Chakravarty
2019 NeuroImage  
Application of non-negative matrix factorization identifies spatial components (clusters of voxels sharing similar covariance patterns), as well as subject weightings (individual variance across hippocampus  ...  In this work we use non-negative matrix factorization to identify patterns of microstructural variance in the human hippocampus.  ...  Data processing was performed in part using the General Purpose Cluster resources of the SciNet HPC Consortium (Loken et al., 2010) .  ... 
doi:10.1016/j.neuroimage.2019.116348 pmid:31715254 fatcat:g6o2ydjg5nc5rp26izpxjhggxu

ACNP 58th Annual Meeting: Poster Session III

2019 Neuropsychopharmacology  
Background: Current psychiatric taxonomy segregates pediatric anxiety symptoms into distinct diagnostic subtypes that are supported by behavioral observations and factor analyses.  ...  Background: Pain symptoms are common among Iraq/Afghanistan-era veterans, and many experience persistent pain symptoms ACNP 58 th Annual Meeting: Poster Session III Although the majority of findings have  ...  To identify distinct patterns of psychiatric disorders and traumas associated with suicide attempts, we derived network cliques representing clusters of risk factors that co-occurred more frequently than  ... 
doi:10.1038/s41386-019-0547-9 pmid:31801974 pmcid:PMC6957926 fatcat:dd7d43ysfvc5bbbstfl73szya4

27th Annual Computational Neuroscience Meeting (CNS*2018): Part One

2018 BMC Neuroscience  
Acknowledgements This research was supported by NIH grant NS086082 and a GSU Brains and Behavior Seed Grant (DNC), N.H. is a Brains and Behavior and Honeycutt Fellow; A.A.P. is a 2CI Neurogenomics and  ...  Brain", the German Research Foundation (DFG; KFO 219, TP9) and the European Union's Horizon 2020 research and innovation programme (HBP SGA1, grant no. 720270 and no. 754304).  ...  A combination of nonnegative matrix factorization (NMF) and sparse coding, NSC allows populations of neurons to collectively encode high-dimensional stimuli spaces using a compressed, sparse, and parts-based  ... 
doi:10.1186/s12868-018-0452-x pmid:30373544 pmcid:PMC6205781 fatcat:xv7pgbp76zbdfksl545xof2vzy

Index and biological spectrum of human DNase I hypersensitive sites

Wouter Meuleman, Alexander Muratov, Eric Rynes, Jessica Halow, Kristen Lee, Daniel Bates, Morgan Diegel, Douglas Dunn, Fidencio Neri, Athanasios Teodosiadis, Alex Reynolds, Eric Haugen (+8 others)
2020 Nature  
within the human genome sequence, providing a common coordinate system for regulatory DNA.  ...  We created high-resolution maps of DHSs from 733 human biosamples encompassing 438 cell and tissue types and states, and integrated these to delineate and numerically index approximately 3.6 million DHSs  ...  Senarighi for expert assistance with scientific illustration and T. Mercer and C. Lundberg for figure layout consultation.  ... 
doi:10.1038/s41586-020-2559-3 pmid:32728217 fatcat:d5ao2qmp7fam5hzb3qsfze6r7i

A Unifying Statistical Framework to Discover Disease Genes from GWAS [article]

Justin N.J. McManus, Robert J. Lovelett, Daniel Lowengrub, Sarah Christensen
2022 bioRxiv   pre-print
We validate each component of the statistical framework individually and in combination.  ...  The combined performance of the map on high-throughput functional genomics and eQTL datasets supersedes the state of the art.  ...  We used the Storey-Tibshirani (Storey and Tibshirani, 2003) method to adjust for multiple comparisons, and considered genes significant with q < 0.05 and p HEIDI > 0.05; the latter is the mechanism to  ... 
doi:10.1101/2022.04.28.489887 fatcat:ct5ue3a6kvcg5oiip2guhvhtre

ÉCole De Physique Des Houches [chapter]

2007 Les Houches  
The Mont Blanc is the highest mountain in the Alps, Western Europe and the European Union.  ...  It rises 4,810.45 m above sea level and is ranked 11th in the world in topographic prominence. ecole de Physique des houches la côte des chavants 74310 les houches, france +33 (0)4 50 54 40 69  ...  Naz Chaudary and Dr. Richard Hill for providing the ME180 tumor bearing mice and Mr. Michael Dunne for providing the H520 tumor bearing mice. Acknowledgement/References: 1.  ... 
doi:10.1016/s0924-8099(13)60020-7 fatcat:jydcwidbbnf3nppqp4x3pyu6ga

École de Physique des Houches [chapter]

2008 Les Houches  
The Mont Blanc is the highest mountain in the Alps, Western Europe and the European Union.  ...  It rises 4,810.45 m above sea level and is ranked 11th in the world in topographic prominence. ecole de Physique des houches la côte des chavants 74310 les houches, france +33 (0)4 50 54 40 69  ...  Naz Chaudary and Dr. Richard Hill for providing the ME180 tumor bearing mice and Mr. Michael Dunne for providing the H520 tumor bearing mice. Acknowledgement/References: 1.  ... 
doi:10.1016/s0924-8099(13)60004-9 fatcat:nxiezedqabbbtnfqonvw6c3doi

École de Physique des Houches [chapter]

2006 Les Houches  
The Mont Blanc is the highest mountain in the Alps, Western Europe and the European Union.  ...  It rises 4,810.45 m above sea level and is ranked 11th in the world in topographic prominence. ecole de Physique des houches la côte des chavants 74310 les houches, france +33 (0)4 50 54 40 69  ...  Naz Chaudary and Dr. Richard Hill for providing the ME180 tumor bearing mice and Mr. Michael Dunne for providing the H520 tumor bearing mice. Acknowledgement/References: 1.  ... 
doi:10.1016/s0924-8099(06)80084-3 fatcat:6w7diik2k5af7cpowh4xz3nsky

The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

Michael W. Weiner, Dallas P. Veitch, Paul S. Aisen, Laurel A. Beckett, Nigel J. Cairns, Robert C. Green, Danielle Harvey, Clifford R. Jack, William Jagust, Enchi Liu, John C. Morris, Ronald C. Petersen (+8 others)
2013 Alzheimer's & Dementia  
An alternative approach using nonnegative matrix factorization was described by Padilla et al [119] and achieved an accuracy of 86.6%, a sensitivity of 87.5% and a specificity of 85.4% in the classification  ...  Stein et al [290] conducted a GWAS investigating genetic influences in caudate volume, a structure involved in many disorders including depression and schizophrenia as well as in AD.  ... 
doi:10.1016/j.jalz.2013.05.1769 pmid:23932184 pmcid:PMC4108198 fatcat:epydl5poq5evrobxws3qerdolu

The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

Michael W. Weiner, Dallas P. Veitch, Paul S. Aisen, Laurel A. Beckett, Nigel J. Cairns, Robert C. Green, Danielle Harvey, Clifford R. Jack, William Jagust, Enchi Liu, John C. Morris, Ronald C. Petersen (+7 others)
2012 Alzheimer's & Dementia  
An alternative approach using nonnegative matrix factorization was described by Padilla et al [119] and achieved an accuracy of 86.6%, a sensitivity of 87.5% and a specificity of 85.4% in the classification  ...  Stein et al [290] conducted a GWAS investigating genetic influences in caudate volume, a structure involved in many disorders including depression and schizophrenia as well as in AD.  ... 
doi:10.1016/j.jalz.2011.09.172 pmid:22047634 pmcid:PMC3329969 fatcat:kkpjb6lv6zbe3lkv7nllgxdnga

Dynamic Handwriting Analysis for Neurodegenerative Disease Assessment: A Literary Review

Gennaro Vessio
2019 Applied Sciences  
The net result is that dynamic handwriting analysis is a powerful, noninvasive, and low-cost tool for real-time diagnosis and follow-up of PD and AD.  ...  Studying the effects of neurodegeneration on handwriting has emerged as an interdisciplinary research topic and has attracted considerable interest from psychologists to neuroscientists and from physicians  ...  A stroke corresponds to a single trait of the handwritten pattern which is connected and continuous, i.e., between two consecutive pen-lifts.  ... 
doi:10.3390/app9214666 fatcat:4bogkmvnpbcebj6sbykqcfg5f4

Special issue on information reuse and integration

2007 IEEE Transactions on Systems Man and Cybernetics Part B (Cybernetics)  
Unfortunately in real world environments, the presence of low quality imbalanced data is a common occurrence.  ...  Low quality or noisy data, which typically consists of erroneous values for both dependent and independent variables, has been demonstrated to have a significantly negative impact on the classification  ...  Janez Brest and prof. dr. Viljem Žumer.  ... 
doi:10.1109/tsmcb.2007.912701 fatcat:xvhlaf4m3vhcdb2cicqtfrug6m

Vol. 6, No. 1 (Full Issue)

2007 Journal of Modern Applied Statistical Methods  
This article attempts to summarize most of those measures, with their attendant advantages and disadvantages.  ...  Educational and Psychological Measurement, 62, 197-226. Fidler, F., & Thompson, B. (2001). Computing correct confidence intervals for ANOVA fixed and random-effects effect sizes.  ...  Educational and Psychological Measurement, 63, 537-553. Bayarri, M.J., & Berger, J. O. ( 2004 ). The interplay of Bayesian and frequentist analysis. Statistical Science, 19, 58-80 Bird, K. D.  ... 
doi:10.22237/jmasm/1177994100 fatcat:tucmx3fugbdhvhrrddidy7b6qm
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