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Colicin Biology

E. Cascales, S. K. Buchanan, D. Duche, C. Kleanthous, R. Lloubes, K. Postle, M. Riley, S. Slatin, D. Cavard
2007 Microbiology and Molecular Biology Reviews  
These applications exploit properties listed below, which are related to (i) bacterial containment, (ii) biosensing of genotoxic compounds, (iii) improvement in protein purification, (iv) production of  ...  (A) Crystal structure of ColE9 H551A (equivalent to His103 in the isolated E9 DNase) bound to 8-mer dsDNA showing the bound catalytic Mg 2ϩ ion (red sphere) in the context of the Im9 exosite (blue shading  ... 
doi:10.1128/mmbr.00036-06 pmid:17347522 pmcid:PMC1847374 fatcat:qqv6j75h7ngm7i745hbxyepspu

Molecular biology and pathogenicity of mycoplasmas

S Razin, D Yogev, Y Naot
1998 Microbiology and Molecular Biology Reviews  
The significant genome compaction that occurred in mycoplasmas was made possible by adopting a parasitic mode of life.  ...  The recent sequencing of the entire genomes of Mycoplasma genitalium and M. pneumoniae has attracted considerable attention to the molecular biology of mycoplasmas, the smallest self-replicating organisms  ...  Pollack for critical reading of the manuscript. Their comments and suggestions are greatly appreciated.  ... 
pmid:9841667 pmcid:PMC98941 fatcat:ekzlhjdxdjcqnemwtkm26pdsoq

Molecular Biology and Pathogenicity of Mycoplasmas

Shmuel Razin, David Yogev, Yehudith Naot
1998 Microbiology and Molecular Biology Reviews  
The significant genome compaction that occurred in mycoplasmas was made possible by adopting a parasitic mode of life.  ...  The recent sequencing of the entire genomes of Mycoplasma genitalium and M. pneumoniae has attracted considerable attention to the molecular biology of mycoplasmas, the smallest self-replicating organisms  ...  Pollack for critical reading of the manuscript. Their comments and suggestions are greatly appreciated.  ... 
doi:10.1128/mmbr.62.4.1094-1156.1998 fatcat:quag2ufklzaphdpgt6etwlddi4

The PLOS Biology XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months

Lauren A. Richardson, Sandra L. Schmid, Avinash Bhandoola, Christelle Harly, Anders Hedenström, Michael T. Laub, Georgina M. Mace, Piali Sengupta, Ann M. Stock, Andrew F. Read, Harmit S. Malik, Mark Estelle (+2 others)
2019 PLoS Biology  
In October of 2018 PLOS Biology celebrated its 15-year anniversary.  ...  In addition to the hierarchical classification of EAPs, the article also revealed other key principles of CCP dynamics (Fig 1) .  ...  If the life sciences suffer from an excess of unreproducible findings, the ethical oversight (in both senses of the term) is partly to blame.  ... 
doi:10.1371/journal.pbio.3000180 pmid:30811478 pmcid:PMC6411196 fatcat:5b2cwtdfobgjdihpfipdfvzmp4

Vehicles, Replicators, and Intercellular Movement of Genetic Information: Evolutionary Dissection of a Bacterial Cell

Matti Jalasvuori
2012 International Journal of Evolutionary Biology  
In this discussion I perform a dissection for a bacterial cell in order to simplify the diversity into components that may help approach the ocean of details in evolving microbial worlds.  ...  of different replicators in general.  ...  Acknowledgments This work was supported by the Academy of Finland. The author wants to thank the reviewer for helpful comments especially on the host ranges of replicators.  ... 
doi:10.1155/2012/874153 pmid:22567533 pmcid:PMC3332184 fatcat:i5siyrv2avadjbsoffm3q3meqi

Resource Letter: Bio-molecular Nano-machines: where Physics, Chemistry, Biology and Technology meet [article]

Debashish Chowdhury
2008 arXiv   pre-print
Cell is the structural and functional unit of life.  ...  Although, traditionally, these machines were subjects of investigation in biology and biochemistry, increasing use of the concepts and techniques of physics in recent years have contributed to the quantitative  ...  However, these phenomena will be reconsidered again in part IV in the broader contexts of cell motility and cell division.  ... 
arXiv:0807.2731v1 fatcat:ho2pcrnn4ndp3haxuijbdtpo6y

Calcium Orthophosphates in Nature, Biology and Medicine

Sergey Dorozhkin
2009 Materials  
For example, self-setting hydraulic cements made of calcium orthophosphates are helpful in bone repair, while titanium substitutes covered by a surface layer of calcium orthophosphates are used for hip  ...  Thus ere calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided.  ...  Therefore, organisms have had a great deal of time to exploit the feedback between composition and structure in apatite, on the one hand, and benefit from its biological functionality, on the other.  ... 
doi:10.3390/ma2020399 fatcat:jrwwvjq2znconfp5b6cbiur3p4

The Human SLC1A5 (ASCT2) Amino Acid Transporter: From Function to Structure and Role in Cell Biology

Mariafrancesca Scalise, Lorena Pochini, Lara Console, Maria A. Losso, Cesare Indiveri
2018 Frontiers in Cell and Developmental Biology  
An intriguing function has been described for ASCT2 that is exploited as a receptor by a group of retroviruses to infect human cells.  ...  After identification of murine and human genes, the function of the coded protein has been studied in cell system and in proteoliposomes revealing that this transporter is a Na + dependent antiporter of  ...  not studied in the context of a metabolic network.  ... 
doi:10.3389/fcell.2018.00096 pmid:30234109 pmcid:PMC6131531 fatcat:faf2rgryt5gobopmh5wjmv55ce

REVIEW: Optimality models in the age of experimental evolution and genomics

J. J. BULL, I.-N. WANG
2010 Journal of Evolutionary Biology  
A few studies of microbes have begun to pioneer this new direction. Incompatibility between the assumed and actual genetics has been demonstrated to be the cause of model failure in some cases.  ...  First, an experimental context with a well-researched organism allows dissection of the evolutionary process to identify causes of model failure -whether the model is wrong about genetics or selection.  ...  Heineman have helped JJB appreciate the value of understanding genetics in testing optimality models and other types of evolutionary predictions.  ... 
doi:10.1111/j.1420-9101.2010.02054.x pmid:20646132 pmcid:PMC3004014 fatcat:stagypzyzraqdovcxdkrdctrre

Save the tree of life or get lost in the woods

Ruben E Valas, Philip E Bourne
2010 Biology Direct  
We propose a duality where we must consider variation of genetic material in terms of networks and selection of cellular function in terms of trees.  ...  Function follows more of a tree-like structure than genetic material, even in the presence of horizontal transfer.  ...  Placing sequence trees in their cellular context So far we have argued the large role vertical inheritance of function has played in evolution is larger than the network of genomes implies.  ... 
doi:10.1186/1745-6150-5-44 pmid:20594329 pmcid:PMC2910001 fatcat:bgux4hysmjaappfdbhpntsei5q

Phylogenetic Inferences from Molecular Sequences: Review and Critique

Luciano Brocchieri
2001 Theoretical Population Biology  
Causes contributing to these conflicts relate to ambiguities in identifying homologous characters of alignments, sensitivity of tree-making methods to unequal evolutionary rates, biases in species sampling  ...  , unrecognized paralogy, functional differentiation, loss of phylogenetic informational content due to long branches or fast evolution, and difficulties with the assumptions and approximations used to  ...  Philippe for critical reading of the manuscript and S. Karlin for helpful comments and discussions. Supported by NIH Grants 5R01GM10452-33 and 2R01HG00335-09.  ... 
doi:10.1006/tpbi.2000.1485 pmid:11243926 fatcat:q3exz4rjlrdqzpm3g2fvjirn4m

93rd National Congress of the Italian Society of Experimental Biology | Palermo, Italy, 22-25 April 2021

The Editors
2021 Journal of Biological Research  
This abstract book contains the abstracts presented at the 93rd National Congress of the Italian Society of Experimental Biology; Palermo, Italy, 22-25 April 2021.  ...  The present research was supported partly by the program: "Support for researchers with emphasis on young researchers -cycle B" in the framework of the Operational Program "Human Resources Development,  ...  This work was supported by the University Research Project Grant (PIACERI Found -NATURE-OA -2020-2022), Department of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, Italy.  ... 
doi:10.4081/jbr.2021.9820 fatcat:4yqk4yufsnayvanfiztusrj5iq

The Rhizome of the Multidrug-Resistant Enterobacter aerogenes Genome Reveals How New "Killer Bugs" Are Created because of a Sympatric Lifestyle

Seydina M. Diene, Vicky Merhej, Mireille Henry, Adil El Filali, Véronique Roux, Catherine Robert, Saïd Azza, Frederick Gavory, Valérie Barbe, Bernard La Scola, Didier Raoult, Jean-Marc Rolain
2012 Molecular biology and evolution  
The genealogic tree of the 162,202 bp multidrug-resistant conjugative plasmid shows that it is a chimera of transposons and integrative conjugative elements from various bacterial origins, resembling a  ...  Moreover, we demonstrate biologically that a G53S mutation in the pmrA gene results in colistin resistance.  ...  They also thank the American Journal of Experts for English corrections.  ... 
doi:10.1093/molbev/mss236 pmid:23071100 fatcat:vlp2r6u5d5durmwcqiyqrdpvku

Poster Abstracts

2014 Integrative and Comparative Biology  
Here, we test the hypothesis of functional valving in the coelom by directly measuring hemolymph pressures in two regions of the body in the American grasshopper (Schistocerca americana).  ...  .; MAGIE, C.Small GTPases and the cell biology of early development in the cnidarian, Nematostella vectensis Understanding how morphogenesis is controlled in early−branching metazoans, coupled with comparisons  ...  ., rich patch exploitation). The two hypotheses make different predictions concerning life history trade−offs.  ... 
doi:10.1093/icb/icu009 fatcat:bwtfvcxovnfbtaglzx7irgcu7m
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