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Experiences in process domain engineering at PRC Inc

C.R. Hollenbach
Proceedings 10th International Software Process Workshop  
This paper briefly describes experiences at PRC Inc. in performing domain engineering on software process domains.  ...  At PRC, domain engineering is applicable to software processes, beneficial to organizations at varying levels of process capability, dependent upon sustained managerial support, and helpful in evolving  ...  PRC Inc., a software and systems integrator located in Washington DC, is interested in improving the process capability of its 7000 person organization.  ... 
doi:10.1109/ispw.1996.654376 dblp:conf/ispw/Hollenbach96 fatcat:hfgoz2cozfhmte2xjdevmz37x4

The SOP for Miniaturized, Mixed-Signal Computing, Communication, and Consumer Systems of the Next Decade

R.R. Tummala, M. Swaminathan, M.M. Tentzeris, J. Laskar, G.-K. Chang, S. Sitaraman, D. Keezer, D. Guidotti, Z. Huang, K. Lim, L. Wan, S.K. Bhattacharya (+3 others)
2004 IEEE Transactions on Advanced Packaging  
The concept of system-on-package (SOP) originated in the mid-1990s at the NSF-funded Packaging Research Center at the Georgia Institute of Technology.  ...  at IC level and at package level.  ...  Currently, he is Byers Eminent Scholar Chair Professor and Georgia Research Alliance Eminent Scholar in Optical Networking in the School of Electrical and Computer Engineering at the Georgia Institute  ... 
doi:10.1109/tadvp.2004.830353 fatcat:7uq5ew6hdjebzmmtbgii2yfuj4

An industrial study of reuse, quality, and productivity

William B Frakes, Giancarlo Succi
2001 Journal of Systems and Software  
The data domains are: text retrieval, user interface, distributed repository, medical records. Reuse in this paper is ad hoc, black box, compositional code reuse.  ...  The data generally show that more reuse results in higher quality, but are ambiguous regarding the relationship between amount of reuse and productivity. Ó  ...  Cardino for their help in ®nding data, CIM-EXP (Budapest, Hungary), PRC (Falls Church, VA), and Software Uno S.r.l. (Padova, Italy) for the data they provided us.  ... 
doi:10.1016/s0164-1212(00)00121-7 fatcat:txmrgadt6vhcnk6vwxmcbkz3ee

Inhibition of HIV-1 Tat-mediated LTR transactivation and HIV-1 infection by anti-Tat single chain intrabodies

A M Mhashilkar, J Bagley, S Y Chen, A M Szilvay, D G Helland, W A Marasco
1995 EMBO Journal  
The anti-Tat sFvs with specific binding activity against the N-terminal activation domain of Tat, block Tat-mediated transactivation of HIV-1 LTR as well as intracellular trafficking of Tat in mammalian  ...  These anti-Tat single chain intrabodies (anti-Tat sFvs) are additionally modified with a C-terminal human C kappa domain to increase cytoplasmic stability and/or the C-terminal SV40 nuclear localization  ...  A portion of this work was also funded by Virus Research Institute, Inc., the Norwegian Cancer Society (LMK), the Norwegian Research Council for Science and Technology (NTNF) and the Norwegian Society  ... 
pmid:7537216 pmcid:PMC398241 fatcat:ar5xkk7ambh57jjvp2hfto3ysm

Angiotensin II Receptor Endocytosis Involves Two Distinct Regions of the Cytoplasmic Tail

Walter G. Thomas, Kenneth M. Baker, Thomas J. Motel, Thomas J. Thekkumkara
1995 Journal of Biological Chemistry  
for this process.  ...  In the present study, we have stably and transiently expressed wild type and carboxyl terminus mutated AT 1A receptors in Chinese hamster ovary cells to identify regions and specific amino acids important  ...  Our data implicate two separate domains within the carboxylterminal region of the AT 1A receptor in endocytosis and identify key amino acids involved in this process.  ... 
doi:10.1074/jbc.270.38.22153 pmid:7673193 fatcat:efkwnlwkbffktaeolgphoypj6a

Using filtering agents to improve prediction quality in the GroupLens research collaborative filtering system

Badrul M. Sarwar, Joseph A. Konstan, Al Borchers, Jon Herlocker, Brad Miller, John Riedl
1998 Proceedings of the 1998 ACM conference on Computer supported cooperative work - CSCW '98  
We identify and evaluate metrics for assessing the effectiveness of filterbots specifically, and filtering system enhancements in general.  ...  Collaborative filtering systems help address information overload by using the opinions of users in a community to make personal recommendations for documents to each user.  ...  In four of the five newsgroups, we found at least one filterbot that improved both coverage and accuracy, measured both by ROC and PRC.  ... 
doi:10.1145/289444.289509 dblp:conf/cscw/SarwarKBHMR98 fatcat:l6ayrn7ox5duznu4ehvizmldgu

TIPSTER lessons learned

Harold Corbin, Aaron Temin
1996 Proceedings of a workshop on held at Baltimore, Maryland October 13-15, 1998 -  
PRC, Inc., was the systems engineering and configuration management (SE/CM) contractor for the TIPSTER program, phases II and III (1994-1998) .  ...  INTRODUCTION The TIPSTER architecture is a domain-specific software architecture (DSSA) for the text processing domain.  ... 
doi:10.3115/1119089.1119094 dblp:conf/tipster/CorbinT98 fatcat:y7fbtogeovd65dcapyk4ie324i

Properties of avian retrovirus particles defective in viral protease

L Stewart, G Schatz, V M Vogt
1990 Journal of Virology  
Results from UV cross-linking experiments show that the gag polyprotein of mutant virions interacts with viral RNA and that this interaction occurs through the nucleocapsid (NC) domain.  ...  However, within mutant virions the interaction of the NC domain with RNA differs from that of mature NC with RNA in wild-type virions.  ...  ADDENDUM IN PROOF We have constructed an alternative PR mutant, D37N, and found that it behaves in every manner like the D371 mutant described herein.  ... 
pmid:1697912 pmcid:PMC248000 fatcat:mqqlsvqnxbejplxjig26uvmptm

Properties of avian retrovirus particles defective in viral protease

L Stewart, G Schatz, V M Vogt
1990 Journal of Virology  
In the avian sarcomaleukosis virus (ASLV) system, the gag gene product is a 76-kilodalton (kDa) polyprotein, Pr76 , which is composed of five major protein domains that are released by proteolytic processing  ...  Results from UV cross-linking experiments show that the gag polyprotein of mutant virions interacts with viral RNA and that this interaction occurs through the nucleocapsid (NC) domain.  ...  ADDENDUM IN PROOF We have constructed an alternative PR mutant, D37N, and found that it behaves in every manner like the D371 mutant described herein.  ... 
doi:10.1128/jvi.64.10.5076-5092.1990 fatcat:ol2igff3bjfxxpqzm2mnkoqx2m

Platelet Rich Concentrate Promotes Early Cellular Proliferation and Multiple Lineage Differentiation of Human Mesenchymal Stromal CellsIn Vitro

Samuel Shani, Raja Elina Ahmad, Sangeetha Vasudevaraj Naveen, Malliga Raman Murali, Karunanithi Puvanan, Azlina Amir Abbas, Tunku Kamarul
2014 The Scientific World Journal  
The gene expression of markers for osteocytes (ALP, RUNX2), chondrocytes (SOX9, COL2A1), and adipocytes (PPAR-γ) was determined at each time point in hMSC treated with 15% activated and nonactivated PRC  ...  However, protein expression study showed formation of oil globules from day 4, significant increase in ALP at days 6 and 8(P≤0.05), and increased glycosaminoglycan levels at all time points(P<0.05), suggesting  ...  PRC was added only once at the beginning without any change of media throughout the experiment.  ... 
doi:10.1155/2014/845293 pmid:25436230 pmcid:PMC4243129 fatcat:g4eajtymabdsrjrruzgy5hxdqu

Front Matter: Volume 1514

1990 15th International Conference on Infrared and Millimeter Waves  
HALL EXPERIMENTS ON SHALLOW DONOR TRANSI-TIONS IN n GaAs -J.  ...  Itoh, Department of Electrical and Computer Engineering, The U of Texas at Austin, Austin, TX 78712 W5.2 DESIGN OF A SINGLE-PERIOD 8.6 GHz TM0l-TMn SERPENTINE MODE CON VERTER AND TMoi AND TMn BENDS IN  ... 
doi:10.1117/12.2301411 fatcat:6j3ef3wm6fekfanobggkq2jota

Regulation of Chemotactic and Proadhesive Responses to Chemoattractant Receptors by RGS (Regulator of G-protein Signaling) Family Members

Edward P. Bowman, James J. Campbell, Kirk M. Druey, Astrid Scheschonka, John H. Kehrl, Eugene C. Butcher
1998 Journal of Biological Chemistry  
In contrast, RGS2, a regulator of G␣ q activity, had no effect on cell migration to any chemoattractant.  ...  Little is known about the GTPase activity of the G␣ i proteins involved in adhesion and chemotaxis, or the significance of their regulation to these responses.  ...  Cells were resuspended in RPMI 1640 at 1.0 -1.5 ϫ 10 8 /ml and 0.8 ml of cells transferred to an Electro Chamber (0.4-cm gap, Life Technologies, Inc.).  ... 
doi:10.1074/jbc.273.43.28040 pmid:9774420 fatcat:hiv3uqhnc5h4jal7shxy27qize

Integrated decision and control of human-engineered complex systems

D. K. Tolani, A. Ray, J. F. Horn
2006 International Journal of General Systems  
Based on the information derived from the observed time series data, the DES decision and control at the upper tier may decide to switch, in real time, to one control module from another in order to satisfy  ...  To assure desired quality at permissible levels of risk as well as under different operating conditions, the PRC at the lower tier makes a trade off between robustness and performance, while damage mitigation  ...  Acknowledgements The authors would like to thank Yasar Murat, Jialing Chen and Derek Bridges for their support in constructing and maintaining the rotorcraft simulation test  ... 
doi:10.1080/03081070600660962 fatcat:ikko7akl6fbvzgrq3ewogv3epu

Low Power Mixed-Signal SoC Integration and Verification Challenges with Third Party IP Cores

Ruchi Shankar, Prachi Mishra, Abhinav Parashar, Ashwini Padoor, Lakshmanan Balasubramanian
2019 EAI Endorsed Transactions on Cloud Systems  
These components include checklists, automated IC analysis programs, and processes both internal and collaborative.  ...  This paper outlines design and DV challenges and resolution in integrating third party IPs in today's high-end ASICs/SoCs.  ...  Inc. for their contributions to the development of the methodology and execution of the same during the aforementioned product development.  ... 
doi:10.4108/eai.5-11-2019.162592 fatcat:mvhtnkr6rfhszmnei4rbnbdmvm

pH-sensitive vibrational probe reveals a cytoplasmic protonated cluster in bacteriorhodopsin

Victor A. Lorenz-Fonfria, Mattia Saita, Tzvetana Lazarova, Ramona Schlesinger, Joachim Heberle
2017 Proceedings of the National Academy of Sciences of the United States of America  
Experiments at the same pH using two different buffer molecules (e.g., phosphate vs.  ...  We assign the second component of the continuum band to the proton uptake complex, a cluster with an excess proton reminiscent to the PRC but located in the cytoplasmic domain and possibly stabilized by  ...  Nanosecond IR experiments (78, 79) at different pH values will be required in the future to characterize the exact timing of this early proton uptake process, as well as to understand its potential role  ... 
doi:10.1073/pnas.1707993114 pmid:29203649 pmcid:PMC5754764 fatcat:wf43z27zjbdbjjipt7jahegz6u
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