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Modulation of mGlu2 Receptors, but Not PDE10A Inhibition Normalizes Pharmacologically-Induced Deviance in Auditory Evoked Potentials and Oscillations in Conscious Rats

Abdallah Ahnaou, Ria Biermans, Wilhelmus H. Drinkenburg, Joohyung Lee
2016 PLoS ONE  
Acknowledgments The authors thank Callum Walsh for editing assistance with the manuscript. Author Contributions Conceived and designed the experiments: AA RB WD. Performed the experiments: AA RB.  ...  Analyzed the data: AA RB. Contributed reagents/materials/analysis tools: AA RB. Wrote the paper: AA WD.  ...  Animals were not used in equal numbers and baseline AEP responses were examined before the pharmacological experiments in order the examine the quality of EEG signal and the S2/S1 ratio measures.  ... 
doi:10.1371/journal.pone.0147365 pmid:26808689 pmcid:PMC4726622 fatcat:arbqzph53reo5kepzxj5worcii

Individual Larvae of the Zebrafish MutantbelladonnaDisplay Multiple Infantile Nystagmus-Like Waveforms that Are Influenced by Viewing Conditions

Sabina P. Huber-Reggi, Kaspar P. Mueller, Dominik Straumann, Melody Ying-Yu Huang, Stephan C. F. Neuhauss
2014 Investigative Ophthalmology and Visual Science  
jerk oscillations regarding the beating direction of the first saccade or waveform amplitude.  ...  Moreover, the effects of the characteristics of a preceding optokinetic response (OKR), of the field of view, and of the eye orbital position were analyzed. RESULTS.  ...  Acknowledgments The authors thank Christian Grimm, Maarten Frens, and Chris Bockisch for fruitful discussion, Matthias Gesemann for critical reading of the manuscript, and Kara Dannenhauer for excellent  ... 
doi:10.1167/iovs.13-13576 pmid:24867578 fatcat:rbch6p3ecfcjpjh77mrzhtcnyi

Time-Specific Fear Acts as a Non-Photic Entraining Stimulus of Circadian Rhythms in Rats

Blake A. Pellman, Earnest Kim, Melissa Reilly, James Kashima, Oleksiy Motch, Horacio O. de la Iglesia, Jeansok J. Kim
2015 Scientific Reports  
, integrated part of the animals' lives.  ...  In response to unsignaled nocturnal shock, animals switched their natural feeding and activity from the dark phase to the light phase.  ...  We thank Bill Schwartz for helpful discussions and comments on the manuscript, and Chris Lloyd and Emmanuel Vlamakis for their assistances in modifying the ANY-maze software.  ... 
doi:10.1038/srep14916 pmid:26468624 pmcid:PMC4606733 fatcat:x3dnhflfibecjng5erkmohywma

Page 60 of None Vol. 50, Issue 6 [page]

2004 None  
To determine /) whether the mitochondrial membrane potential of a cell is oscillating and 2) the closeness of the waveform to a perfect sinusoidal waveform of the same frequency, we generated a measure  ...  Given that an oscillating cell has a dominant frequency, the extent to which this waveform can be fitted to a perfect sinusoid of the appropriate dominant frequency is deter- mined as the regularity of  ... 

Association of Doppler Wave Pattern of Hepatic Veins and Fatty Liver Disease Degree

Cibele F Carvalho Cristina Chammas
2015 Journal of Liver  
The objective of this study was to document the progressive effects of fatty infiltration of the liver on hepatic veins (HVs) by measuring Doppler waveforms in groups of rats and dogs.  ...  The Doppler sonography spectra of HVs were classified into three groups: normal or triphasic waveforms, biphasic waveforms, and monophasic or flat waveforms.  ...  Carvalho to the Radiology Institute of University of São Paulo in partial satisfaction of the requirements for a Post-Doctoral degree.  ... 
doi:10.4172/2167-0889.1000174 fatcat:pwj4f45a3bhs7cgqqvjkswmrgu

The Membrane Potential Waveform of Bursting Pacemaker Neurons Is a Predictor of Their Preferred Frequency and the Network Cycle Frequency

H.-a. Tseng, F. Nadim
2010 Journal of Neuroscience  
We measured the preferred frequency of the PD neuron in voltage clamp, which allows control of the oscillation voltage range and waveforms (sine waves and realistic oscillation waveforms), and showed that  ...  (1) the preferred frequency depends on the voltage range of the oscillating voltage waveform; (2) the slope of the waveform near its peak has a strongly negative correlation with the preferred frequency  ...  Thus, we decided to examine possible effects of the waveform voltage range on the f max value in the PD neuron.  ... 
doi:10.1523/jneurosci.1818-10.2010 pmid:20702710 pmcid:PMC2944831 fatcat:vu5r46g36rhj7es3ezbxj7fvye

Cannabinoid receptors mediate methamphetamine induction of high frequency gamma oscillations in the nucleus accumbens

Joshua T. Morra, Stanley D. Glick, Joseph F. Cheer
2012 Neuropharmacology  
The effects of drug administration on stereotypy and local gamma oscillations were evaluated. Methamphetamine treatment significantly increased high frequency gamma oscillations (~ 80 Hz).  ...  Due to recent evidence implicating endocannabinoid involvement in brain disorders, including psychosis, we studied the effects of endocannabinoid signaling on neuronal oscillations of rats exhibiting methamphetamine  ...  The current study aimed to examine the relationship between γ oscillations in the ventral striatum and the expression of methamphetamine-induced stereotypy.  ... 
doi:10.1016/j.neuropharm.2012.04.036 pmid:22609048 pmcid:PMC3392334 fatcat:vwnue3bd35bqlg353epzvg3uqm

Effect of Mechanical Loading Timeline on Periosteal Bone Formation

Hiroko N. MATSUMOTO, Yoshihisa KOYAMA, Kazuo TAKAKUDA
2008 Journal of Biomechanical Science and Engineering  
Noticing the possible importance of timeline-dependent phenomena in mechanotransduction, we examined the effects of both the duration of constant load and the duration of rest interval in a 3-point bending  ...  Furthermore, the length of the rest period and the number of loading cycles were found to have significant effects on the amount of bone formation.  ...  Acknowledgements The authors wish to thank Mr. J. Ohtsuka and Mr. K. Nagashima for their help in conducting the animal experiments.  ... 
doi:10.1299/jbse.3.176 fatcat:lczvhmzdpbhqdpoobtltgb4ree

The Effect of Microcirculatory Flow on Oscillating Gradient Diffusion MRI and Diffusion Encoding with Dual-Frequency Orthogonal Gradients (DEFOG)

Dan Wu, Jiangyang Zhang
2016 Magnetic Resonance in Medicine  
Purpose-We investigated the effect of microcirculatory flow on oscillating gradient spin echo (OGSE) diffusion MRI at low b-values and developed a diffusion preparation method called diffusion encoding  ...  with dual-frequency orthogonal gradients (DEFOG) to suppress the effect.  ...  Questions about a similar effect on OGSE diffusion MRI have been recently raised (19) but have not yet been examined.  ... 
doi:10.1002/mrm.26242 pmid:27080566 pmcid:PMC5568088 fatcat:jk5lfewl2zgublajzipebq2rga

Circadian rhythms in electric waveform structure and rate in the electric fish Brachyhypopomus pinnicaudatus

Philip K. Stoddard, Michael R. Markham, Vielka L. Salazar, Susan Allee
2007 Physiology and Behavior  
Sex differences were apparent in strength and magnitude of the circadian oscillations; male oscillations were stronger and larger.  ...  circadian rhythms may result from breakdowns downstream of the central oscillator.  ...  Acknowledgements The research was supported by NIH grants MBRS GM08205 to PKS and MH064550 to MRM. Heather Gamper provided excellent care of the animals.  ... 
doi:10.1016/j.physbeh.2006.08.013 pmid:16996093 pmcid:PMC2426960 fatcat:fgnrcu74mveuffmoijjilnn6r4

Ocular motor abnormalities in achiasmatic mutant Belgian sheepdogs: Unyoked eye movements in a mammal

L.F. Dell'Osso, R.W. Williams
1995 Vision Research  
Foveating and braking saccades and foveation periods were seen in some waveforms. More common were pendular oscillations of both eyes that were essentially independent in amplitude and phase.  ...  Individual dogs from this family provide an animal model of the ocular motor consequences of the disturbed visual input caused by the absence of an optic chiasm and a novel model of CN.  ...  Acknowledgements--Our thanks to Drs Alexander de Lahunta and John Cummings for the invaluable help in finding mutants, to Mary Young for aid in setting up a colony of these animals, to Bonnie Belton for  ... 
doi:10.1016/0042-6989(94)e0045-m pmid:7839601 fatcat:b4cytm2s3vemnheyh2zzqr7h5q

TRPM4 contributes to subthreshold membrane potential oscillations in multiple mouse pacemaker neurons

Keyong Li, Yingtang Shi, Elizabeth C. Gonye, Douglas A. Bayliss
2021 eNeuro  
Under whole cell voltage clamp, inward currents evoked by oscillation voltage waveforms were inhibited in LC by blocking L-type calcium channels and TRPM4.  ...  membrane potential oscillations contribute to the pacemaker-like action potential discharge.  ...  Thus, to characterize the calcium current components evoked by the oscillation voltage waveform we next tested effects of the non-specific calcium channel blocker, Cd 2+ (200 μM, in the continued presence  ... 
doi:10.1523/eneuro.0212-21.2021 pmid:34732535 pmcid:PMC8607911 fatcat:642fvjrn6zfgxpmfsxcapezcfy

Transcranial Alternating Current Stimulation (tACS) Entrains Alpha Oscillations by Preferential Phase Synchronization of Fast-Spiking Cortical Neurons to Stimulation Waveform [article]

Ehsan Negahbani, Iain M. Stitt, Marshall Davey, Thien T. Doan, Moritz Dannhauer, Anna C. Hoover, Angel V Peterchev, Susanne Radtke-Schuller, Flavio Fröhlich
2019 bioRxiv   pre-print
Modeling studies predict that transcranial alternating current stimulation (tACS) entrains brain oscillations, yet direct examination has been lacking or potentially contaminated by stimulation artefact  ...  We found evidence to support the model-driven predictions of how tACS entrains neural oscillations as explained by the triangular Arnold tongue pattern.  ...  The content of current research is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.  ... 
doi:10.1101/563163 fatcat:dsdp54iin5dqfck5slbddg3h24

Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabeticPsammomys obesus

S. M. Katzman, M. A. Messerli, D. T. Barry, A. Grossman, T. Harel, J. D. Wikstrom, B. E. Corkey, P. J. S. Smith, O. S. Shirihai
2004 American Journal of Physiology. Endocrinology and Metabolism  
When mitochondrial membrane potential was averaged from all the cells in a single islet, the resultant waveform demonstrated clear sinusoidal oscillations.  ...  Oscillations  ...  In addition to cross-correlation, we examined the synchronicity of our waveform data with absolute cross-correlation and maximal cross-correlation methods.  ... 
doi:10.1152/ajpendo.00044.2004 pmid:15339741 fatcat:i5bsufedrjhqdnivyp7jahwcwq

Removal of excessive bronchial secretions by asymmetric high-frequency oscillations

L. Freitag, W. M. Long, C. S. Kim, A. Wanner
1989 Journal of applied physiology  
We also examined the effects of asymmetric HFO when combined with postural drainage.  ...  Animals were ventilated with a Harvard respirator at a low frequency with superimposed HFO at 14 Hz with asymmetrical waveforms generated by a digitally controlled electromagnetic piston pump (expiratory  ...  The authors thank Vincent McCaskill for excellent technical support, Hacik Gazeroglu for statistical analysis, and Isabel V. Rodriguez for typing the manuscript.  ... 
doi:10.1152/jappl.1989.67.2.614 pmid:2793662 fatcat:unq7jd7a7ralxbyvjckhqsw4hi
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