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O Ob bj je ec ct ti iv ve e: : This paper presents the case of a patient with a 5-year history of progressive language deterioration, who met the clinical criteria for semantic dementia, a variant of fronto-temporal ... Severity of dementia in patients was evaluated using the Clinical Dementia Rating (CDR). ... O Ob bj je ec ct ti iv ve e: : Frontotemporal dementia (FTD), formerly known as Pick's disease, has become recognized as a distinct and relatively common entity typically characterized by varied behavioral ...doi:10.1017/s1355617710001062 fatcat:kru7xx2k3zeazneuyevxrov3cu
Catania, Catania Introduction: Fatigue is a common non-motor symptom in patients with Parkinson's Disease (PD) and one of the most disabling symptoms of this disease, as reported by patients, with serious ... The primary objectives included the evaluation of the incidence and severity of fatigue in PD patients measured by Parkinson Fatigue Scale (PFS-16) and assessment of its predisposing factors (age, gender ... A single accelerometer was worn with a belt at the level of L5 during the test. ...doi:10.1016/j.baga.2012.10.001 fatcat:tgb5tzfxqbeela4ufactz6hqfu
For example, this is clearly the case with GAD 25 and GAD67, two transcripts expressed by GAD1. ... prefrontal cortex (DLPFC) in a large cohort of normals and patients with schizophrenia, bipolar illness and major depression. ... conditions including anorexia nervosa, and in some cases such maladaptive behavior may perpetuate and exacerbate these conditions. ...doi:10.1038/npp.2013.278 fatcat:expu2u3f3reypazj7tt7jhybfa
With the exception of some populations, only a small minority of cases of PD are caused by known mutations in single genes. ... We used unbiased single cell RNA sequencing to transcriptionally compare fetal VM tissue in 2D and 3D conditions together with a functional analysis performed using whole cell patch clamp technique. ... An important component was the on-going evaluation and training of the community workers by the team of health professionals including physiotherapists and psychologists. ...doi:10.3233/jpd-199900 fatcat:5vfqpicl35co7pzopm2g5lgaem
evaluation of these two radioligands in a healthy rhesus monkey brain. ... In contrast, COX-2 is minimally expressed at baseline in several peripheral tissues but markedly upregulated by inflammation at the level of both gene transcription and protein synthesis. ... One of two variants driving Background: Type 2 diabetes is associated with mild neurocognitive decrements in middle age and an almost two-fold increased risk for dementia in older adults. ...doi:10.1038/npp.2016.242 fatcat:4efd43swjbboranfrcs3pp32h4