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Restore from Restored: Single-image Inpainting [article]

Eunhye Lee, Jeongmu Kim, Jisu Kim, Tae Hyun Kim
2021 arXiv   pre-print
Inpainting has extensive applications in areas of photo editing, restoration, and even video editing (Barnes et al. 2009; Levin et al. 2004; Kim et al. 2019) , and the main goal is to generate plausible  ... 
arXiv:2110.12822v1 fatcat:zlun5wfxa5f7nl5dsvymrqly3i

Selection of the Most Probable Best [article]

Taeho Kim, Kyoung-kuk Kim, Eunhye Song
2022 arXiv   pre-print
Kim, Kim, andSong: Selection of the Most Probable Best 10 Article submitted to Operations Research; manuscript no. lim Kim, Kim, andSong: Selection of the Most Probable Best Article submitted to Operations  ...  Kim, Kim, andSong: Selection of the Most Probable Best Article submitted to Operations Research; manuscript no.  ...  This step samples the covariance matrix from the inverse Wishart distribution. e-companion to Kim, Kim, and Song: Selection of the Most Probable Best Composition of top 15 products sorted based on their  ... 
arXiv:2207.07533v1 fatcat:c3nnzfw7inbxrltdbmkco4ykiq

Novel Small Molecules Capable of Blocking mtRAS-Signaling Pathway

Namkyoung Kim, Injae Shin, Younghoon Kim, Eunhye Jeon, Jiwon Lee, Chaeyoung Lee, Yunju Nam, Sumin Lee, Eunhye Ju, Chan Kim, Woolim Son, SeongShick Ryu (+2 others)
2021 Frontiers in Oncology  
RAS mutants are involved in approximately 30% of all human cancers and have been regarded as undruggable targets owing to relatively smooth protein surface and obscure binding pockets. In our previous study, we have demonstrated that GNF-7, a multi-targeted kinase inhibitor, possesses potent anti-proliferative activity against Ba/F3 cells transformed with NRAS-G12D. Based on our further analysis using Ba/F3 cells transformed with mtRAS, we discovered a series of pyrimido[4,5-d]pyrimidin-2-one
more » ... alogues as mtRAS-signaling pathway blockers. In addition, our efforts expanded the assessment to cancer cells with mtRAS, which revealed that these substances are also capable of strongly suppressing the proliferation of various cancer cells harboring KRAS-G12D (AsPC-1), KRAS-G12V (SW480, DU-145), KRAS-G12C (H358), KRAS-G13D (MDA-MB-231), KRAS-Q61L (HT-29), and NRAS-Q61L (OCI-AML3). We herein report novel and potent mtRAS-signaling pathway blockers, SIJ1795 and SIJ1772, possessing 2 to 10-fold increased anti-proliferative activities compared to those of GNF-7 on cancer cells harboring mtRAS as well as on Ba/F3 cells transformed with mtRAS. Both SIJ1795 and SIJ1772 attenuate phosphorylation of RAS downstream molecules (AKT and MEK) and induce apoptosis and G0/G1 cell cycle arrest on cancer cells with mtRAS. Moreover, both substances substantially suppress the migration, invasion, and colony formation of cancer cells harboring mtRAS. Taken together, this study led us to identification of SIJ1795 and SIJ1772 capable of strongly inhibiting mtRAS-signaling pathway on cancer cells harboring mtRAS.
doi:10.3389/fonc.2021.768022 pmid:34956887 pmcid:PMC8695447 fatcat:m5r2z36ig5h2dfwitau5hriz3u

Restore from Restored: Single-image Inpainting [article]

Eunhye Lee, Jeongmu Kim, Jisu Kim, Tae Hyun Kim
2021 arXiv   pre-print
As an alternative, patch-match-based methods have been * Eunhye Lee, Jeongmu Kim and Jisu Kim are co-first authors. † Tae Hyun Kim is corresponding author.  ... 
arXiv:2102.08078v2 fatcat:rlauvj4tmrgito3sambijecgia

Post-cranioplasty Blindness

Eunhye Lee, Inkyeoung Kim
2016 The Nerve  
Acute visual loss resulting from an uncomplicated cranioplasty is rare. A 52-year-old man presented with computed tomography (CT)-proven acute subdural hematoma in the right frontotemporoparietal area. The patients got a standard craniotomy in supine position. But on postoperative day 24, he was diagnosed postoperative epidural and subdural empyema. The patient underwent infected bone flap removal and evacuation of epidural and subdural empyema. Four months later, he got right
more » ... tal cranioplasty with artificial bone (Medpor) after controlling of infection. But on postoperative day 15, he complained of inability to see with his right eye. Brain and orbital CT, magnetic resonance imaging scan performed postoperatively did not show any new intracranial or intraorbital pathology. There were not any adverse events such as excessive pressure placed on the eyeball or bulky retraction of frontal skin flap. Visual evoked potential revealed prechiasmatic lesion. Fundoscopy showed slightly pallor optic disc of right side. The patient's vision in the right eye remained no light perception permanently. The reason and pathophysiology of the mechanism of this complication should be discussed through reporting more cases.
doi:10.21129/nerve.2016.2.2.90 fatcat:sh33ferrurebppoahkwke36v4i

Dendritic Cell Dysfunction in Patients with End-stage Renal Disease

Ji Ung Kim, Miyeon Kim, Sinae Kim, Tam Thanh Nguyen, Eunhye Kim, Siyoung Lee, Soohyun Kim, Hyunwoo Kim
2017 Immune Network  
doi:10.4110/in.2017.17.3.152 pmid:28680376 pmcid:PMC5484645 fatcat:ofq4ug6x6zbo3j7lxs3nwoqax4

Mapping Tourists' Destination (Dis)Satisfaction Attributes with User-Generated Content

Woohyuk Kim, Sung-Bum Kim, Eunhye Park
2021 Sustainability  
Although the tourism industry has increasingly used social media, there has been little empirical research in terms of the attributes of tourist satisfaction and dissatisfaction with user-generated contents. The purpose of this study is to explore the attributes of tourist satisfaction and dissatisfaction through user-generated contents. We collected data from online review platforms. Our data include historical online reviews, names of reviewers, ratings, location, helpful votes, date of
more » ... , and contributions. In terms of results, the study found 30 key topics related to tourist satisfaction and dissatisfaction. Additionally, we found three clusters (i.e., holiday experience, attractions and facilities, and food experience). Lastly, we that suggested rating levels are different based on the type of tourists (i.e., domestic and international). This study provides discussions and implications for tourism research and industry practices.
doi:10.3390/su132212650 fatcat:himlrz7wzjbghe2kdhvfmlwcja

Contributions of Ammonia to High Concentrations of PM2.5 in an Urban Area

Junsu Park, Eunhye Kim, Sangmin Oh, Haeri Kim, Soontae Kim, Yong Pyo Kim, Mijung Song
2021 Atmosphere  
atmosphere Article Contributions of Ammonia to High Concentrations of PM2.5 in an Urban Area Junsu Park 1,2 , Eunhye Kim 3,4 , Sangmin Oh 1 , Haeri Kim 1 , Soontae Kim 3 , Yong Pyo Kim 5 and  ...  Kim, H.C.; Kim, E.; Bae, C.; Hoon Cho, J.; Kim, B.U.; Kim, S.  ... 
doi:10.3390/atmos12121676 fatcat:2ma27nohg5gzpkuinvnb2x7gte

Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance

Namkyoung Kim, Injae Shin, Jiwon Lee, Eunhye Jeon, Younghoon Kim, Seongshick Ryu, Eunhye Ju, Wonjeong Cho, Taebo Sim
2021 International Journal of Molecular Sciences  
(Eunhye Ju), W.C. synthesized SIJ1227 and its derivatives. N.K., J.L. and E.J. (Eunhye Jeon) conducted biological experiments. S.R. conducted the docking study.  ... 
doi:10.3390/ijms22073783 pmid:33917428 fatcat:wy5qqls4rzbibmtcqvatuzhe34

The Variability of Ozone Sensitivity to Anthropogenic Emissions with Biogenic Emissions Modeled by MEGAN and BEIS3

Eunhye Kim, Byeong-Uk Kim, Hyun Kim, Soontae Kim
2017 Atmosphere  
[42] were used, and we adopted the method proposed by Kim et al. [43] . Cho et al.  ...  Kim et al. [43] updated the dataset with previous studies [44, 45] to estimate biogenic emissions using BEIS3.  ... 
doi:10.3390/atmos8100187 fatcat:rpdj7jitzzh6njtghvhjvlfgbe

Decision on Replacing Components of Security Functions in COTS-Based Information Systems [chapter]

Myeonggil Choi, Hyunwoo Kim, Eunhye Kim, Sehun Kim
2005 Lecture Notes in Computer Science  
As governments and enterprises adopt COTS-based information systems, COTS components must be selected to satisfy the security requirements of applied systems. However, the selection of security components is a trade-off between the confidence level in the components and the cost of replacing components. The higher confidence required of the security components leads to a higher cost in the selection process. Particularly, as governments take into account the confidence-level of COTS-based
more » ... ation systems, they must replace security functional components by their own developing components in high security environment. A decision method is needed to solve the trade-off between security and costs. This paper focuses on decision making to solve the problem of replacing the security functional components in COTS-based systems. This paper suggests an appropriate adaptation level and a cost-effective priority to replace security functional components in security environment. To make a cost effective decision on adapting security functional components, we develop a hierarchical model of information security technologies. Based on this, we determine the priority among security functional components using AHP (Analytic Hierarchy Process). Acknowledgements.
doi:10.1007/978-3-540-30587-3_10 fatcat:32xzuwlccjfhzgd3ol3w4nmxfa

A Kinetic Study on Combustible Coastal Debris Pyrolysis via Thermogravimetric Analysis

Eunhye Song, Daegi Kim, Cheol-Jin Jeong, Do-Yong Kim
2019 Energies  
Coastal debris has recently emerged as a serious environmental pollution problem. Coastal debris can be treated using pyrolysis because it consists mainly of combustible materials like plastics (e.g., polyethylene (PE), polypropylene (PP), nylon) and wood. In this study, the pyrolysis characteristics of coastal debris were fully utilized by applying their basic data to fuel production. The initial temperature increased from 330 °C to 380 °C for the nylon fishing net coastal debris sample, from
more » ... 05.01 °C to 430.08 °C for the PE fishing net coastal debris sample, from 395.01 °C to 419.96 °C for the PP rope coastal debris sample, and from 114.95 °C to 115.02 °C for the wood (bamboo) coastal debris sample. The activation rate of the global activation energy and the pre-exponential factors rose with the increasing heating rate, complementing the reduction rate constant due to the larger growth of the exponential term due to the kinetic models used.
doi:10.3390/en12050836 fatcat:4ff6gmsa3jhbxcgonlezzkoeba

Greater and Lesser Omenta: Normal Anatomy and Pathologic Processes

Eunhye Yoo, Joo Hee Kim, Myeong-Jin Kim, Jeong-Sik Yu, Jae-Joon Chung, Hyung-Sik Yoo, Ki Whang Kim
2007 Radiographics  
doi:10.1148/rg.273065085 pmid:17495288 fatcat:me23pd7zs5adbgt7l7e5geqmti

Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)

Eunhye Kim, Hyunjhung Jhun, Joohee Kim, Unjoo Park, Seunghyun Jo, Areum Kwak, Sinae Kim, Tam T. Nguyen, Yongsun Kang, Insoo Choi, Joongbok Lee, Heijun Kim (+3 others)
2017 Immune Network  
Interferons (IFNs) have been known as antiviral genes and they are classified by type 1, type 2, and type 3 IFN. The type 1 IFN consists of IFNα, IFNβ, IFNτ, and IFNω whereas the type 2 IFN consists of only IFNγ, which is a key cytokine driving T helper cell type 1 immunity. IFNλ belongs to the type 3 IFN, which is also known as IL-28 and IL-29 possessing antiviral activities. Type 1 IFN is produced by viral infection whereas type 2 IFN is induced by mitogenic or antigenic T-cell stimuli. The
more » ... Nτ of bovine was first discovered in an ungulate ruminant recognition hormone. IFNτ belongs to the type 1 IFN with the common feature of type 1 IFN such as antiviral activity. IFNs have been mostly studied for basic research and clinical usages therefore there was no effort to investigate IFNs in industrial animals. Here we cloned porcine IFNα8 from peripheral blood mononuclear cells of Korean domestic pig (Sus scrofa domestica). The newly cloned IFNα8 amino acid sequence from Korean domestic pig shares 98.4% identity with the known porcine IFNα8 in databank. The recombinant porcine IFNα8 showed potent antiviral activity and protected bovine Madin-Darby bovine kidney epithelial (MDBK) cells from the cytopathic effect of vesicular stomatitis virus, but it failed to protect human Wistar Institute Susan Hayflick (WISH) cells and canine Madin-Darby canine kidney epithelial-like (MDCK) cells. The present study demonstrates species specific antiviral activity of porcine IFNα8.
doi:10.4110/in.2017.17.6.424 pmid:29302255 pmcid:PMC5746612 fatcat:37u5uioapfd3fdd2soyoouqnna

Conformance Analysis of Clinical Pathway Using Electronic Health Record Data

Sooyoung Yoo, Minsu Cho, Seok Kim, Eunhye Kim, So Min Park, Kidong Kim, Hee Hwang, Minseok Song
2015 Healthcare Informatics Research  
Objectives: The objective of this study was to confirm the conformance rate of the actual usage of the clinical pathway (CP) using Electronic Health Record (EHR) log data in a tertiary general university hospital to improve the CP by reflecting realworld care processes. Methods: We analyzed the application and matching rates of clinicians' orders with predefined CP order sets based on data from 164 inpatients who received appendectomies out of all patients who were hospitalized from August 2013
more » ... to June 2014. We collected EHR log data on patient information, medication orders, operation performed, diagnosis, transfer, and CP order sets. The data were statistically analyzed. Results: The average value of the actual application rate of the prescribed CP order ranged from 0.75 to 0.89. The application rate decreased when the order date was factored in along with the order code and type. Among CP pre-operation, intra-operation, post-operation, routine, and discharge orders, orders pertaining to operations had higher application rates than other types of orders. Routine orders and discharge orders had lower application rates. Conclusions: This analysis of the application and matching rates of CP orders suggests that it is possible to improve these rates by updating the existing CP order sets for routine discharge orders to reflect data-driven evidence. This study shows that it is possible to improve the application and matching rates of the CP using EHR log data. However, further research should be performed to analyze the effects of these rates on care outcomes.
doi:10.4258/hir.2015.21.3.161 pmid:26279952 pmcid:PMC4532840 fatcat:tldokkagffdvpb776qkevpzmle
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