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Estimation of ultrasound strain indices in carotid plaque and correlation to cognitive dysfunction

X. Wang, D. C. Jackson, C. C. Mitchell, T. Varghese, B. P. Hermann, M. A. Kliewer, R. J. Dempsey
2014 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society  
Non-invasive ultrasound strain imaging may therefore be a viable surrogate to determine the risk of embolic stroke and possible cognitive impairment.  ...  The maximum strain indices of the plaque, defined as mean accumulated strain over a small region of interest in the plaque with large deformations, were obtained.  ...  Department of Energy's Office of Science. The authors would like to thank Ms. Pamela Winne for coordinating the data acquisition on patients.  ... 
doi:10.1109/embc.2014.6944903 pmid:25571271 pmcid:PMC4288023 dblp:conf/embc/WangJMVHKD14 fatcat:oxybfq5znbgpjggigjlm2v66x4

Improved Correlation of Strain Indices with Cognitive Dysfunction with Inclusion of Adventitial Layer with Carotid Plaque

X. Wang, C. C. Mitchell, T. Varghese, D. C. Jackson, B. G. Rocque, B. P. Hermann, R. J. Dempsey
2015 Ultrasonic imaging (Print)  
The Pearson correlation coefficients for maximum shear strain and cognition improved from the previous plaque-only analyses of −0.432 and −0.345 to −0.795 and −0.717 with the plaque-with-adventitia segmentation  ...  Using plaque-only carotid artery segmentations, we recently demonstrated that impaired cognitive function correlated significantly with maximum axial and lateral strain indices within a localized region  ...  Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported in part by National Institutes of Health  ... 
doi:10.1177/0161734615589252 pmid:26025578 pmcid:PMC4662918 fatcat:o67xf7ollvadzm2eiwpedzedki

A Cross-Sectional Investigation of Cognition and Ultrasound-Based Vascular Strain Indices

2019 Archives of Clinical Neuropsychology  
Correlation and ROC analyses were performed between ultrasound strain indices and cognitive function.  ...  We examine the relationship between variability in the plaque strain distribution estimated using ultrasound with multiple cognitive domains including executive, language, visuospatial reasoning, and memory  ...  Support for this research was also provided by the Office of the Vice Chancellor for Research and Graduate Education at the University of Wisconsin-Madison with funding from the Wisconsin Alumni Research  ... 
doi:10.1093/arclin/acz006 pmid:30805597 pmcid:PMC7014973 fatcat:nuurz5zusjf5zau7bzqhuu4e4y

Amelioration of cognitive function in hemodialysis patients in absent of hypotensives episodes

Despina Karasavvidou, Eleni Triantafilidou, Dimitrios Valoukas, Dimitrios Makridis, Sygliti-Errieta Pelidou, Cristos katsinas
2015 Artery Research  
Results: The two groups were different in terms of mean age, pulse pressure/stroke volume, media to lumen ratio and internal diameter of small resistance arteries.  ...  Secondary forms of hypertension were excluded according to standard clinical evaluations and biochemical or instrumental assessment, and in all patients a 24-hour blood pressure monitoring was performed  ...  Speckle-tracking was then used to measure regional circumferential strain of the left common carotid in 6 separate 60 segments of the circumference of the arterial wall in a plaque free plane of the common  ... 
doi:10.1016/j.artres.2015.10.214 fatcat:ocy5fr4w7rha5ni6lwfi6xplve

Motion synchronisation patterns of the carotid atheromatous plaque from B-mode ultrasound

Spyretta Golemati, Eleni Patelaki, Aimilia Gastounioti, Ioannis Andreadis, Christos D. Liapis, Konstantina S. Nikita
2020 Scientific Reports  
Asynchronous movement of the carotid atheromatous plaque from B-mode ultrasound has been previously reported, and associated with higher risk of stroke, but not quantitatively estimated.  ...  Based on the hypothesis that asynchronous plaque motion is associated with vulnerable plaque, in this study, synchronisation patterns of different tissue areas were estimated using cross-correlations of  ...  Kakisis, and Dr. K. Koulia) in collecting the ultrasound image data is gratefully acknowledged.  ... 
doi:10.1038/s41598-020-65340-2 pmid:32641773 fatcat:fxxidnjc7jcz7h7j5bzmvpdrne

Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer's disease

Branko Malojcic, Panteleimon Giannakopoulos, Farzaneh A. Sorond, Elsa Azevedo, Marina Diomedi, Janja Pretnar Oblak, Nicola Carraro, Marina Boban, Laszlo Olah, Stephan J. Schreiber, Aleksandra Pavlovic, Zsolt Garami (+2 others)
2017 BMC Medicine  
of cognitive impairment and dementia, tracking disease progression and evaluating response to treatment in various neurocognitive disorders.  ...  Original articles, systematic literature reviews, guidelines and expert opinions published until September 2016 were critically analysed to summarise existing evidence, indicate gaps in current knowledge  ...  Sorond Research Support: NINDS R01 NS085002; the Swiss National Foundation grants SNF: 320030-129690/1 and SPUM 33CM30-124111; and the European Society of Neurosonology and  ... 
doi:10.1186/s12916-017-0799-3 pmid:28178960 pmcid:PMC5299782 fatcat:ib3rdl3lf5e5hevvc5ghlbxkqa

Carotid intima-media thickness is associated with cognitive deficiency in hypertensive patients with elevated central systolic blood pressure

Eros da Mota Dias, Luiz Tadeu Giollo, Débora Dada Martinelli, Camila Mazeti, Heitor Moreno Júnior, José Fernando Vilela-Martin, Juan Carlos Yugar-Toledo
2012 Cardiovascular Ultrasound  
Thus, the objectives of this study were: to evaluate the relationship between hypertension and cognitive dysfunction (CD), identify risk factors and determine the association between early markers of vascular  ...  The role of hypertension in the loss of cognitive function is controversial.  ...  Similarly, vascular remodeling detected by estimating the carotid IMT has been linked to increased risk of cardiovascular, coronary and brain events; this represents an important step in carotid plaque  ... 
doi:10.1186/1476-7120-10-41 pmid:23078629 pmcid:PMC3495224 fatcat:nukfub5cfzegthdyoufsoqvyyy


2012 Cerebrovascular Diseases  
T2 Carotid and vertebral arteries: classification of stenosis The classification of internal carotid artery and vertebral artery stenosis is of great impact.  ...  Combining these ultrasound criteria, neurosonography allows reliable grading of carotid and vertebral stenoses as a basis for decision making.  ...  Background: Carotid plaque characterization with ultrasound is a reliable diagnostic tool to identify echographic plaque featues indicators of its composition and vulnerability.  ... 
doi:10.1159/000338951 pmid:22652633 fatcat:tvkmom7mpze5zn4tsvsm7tlmje

Diagnostic imaging in the management of patients with metabolic syndrome

Seo Rin Kim, Lilach O. Lerman
2018 Translational Research: The Journal of Laboratory and Clinical Medicine  
The purpose of this review is to summarize advances in diagnostic imaging modalities in MetS that can be applied for evaluating each components and target organs.  ...  This may help in early detection, monitoring target organ injury, and in turn developing novel therapeutic target to alleviate and avert them.  ...  Acknowledgments The authors wish to thank Christopher M. Ferguson, MS, for assistance in preparing the figures. Kim and Lerman Page 15 Transl Res. Author manuscript; available in PMC 2019 April 01.  ... 
doi:10.1016/j.trsl.2017.10.009 pmid:29175480 pmcid:PMC5839955 fatcat:thp7ulguenhbfmrqydnxn4iqry

20th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics. Zadar, Croatia, May 7-11, 2015: Abstracts

2015 Cerebrovascular Diseases  
To be a qualified neurosonologist, it is essential to understand the physics of ultrasound and be able to apply it on a daily basis.  ...  Since multiple ultrasound modes are used during the examination, the examiner has to be familiar with the advantages and disadvantages of these modalities in order to accurately use this diagnostic method  ...  plaque on ultrasound of carotid artery.  ... 
doi:10.1159/000430972 pmid:25967157 fatcat:4x5bua75kzgs7dghwrqremqs4e

19th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics. Rome, Italy, May10-13, 2014: Abstracts

2014 Cerebrovascular Diseases  
In the carotid sinus, in addition to the red laminar flow a blue coded area -so called flow separation zone -can be observed.  ...  Due to the acoustic shadow caused by the transverse processes of the 6 th to the 3 rd vertebrae, this section is the easiest to identify in a B-mode image.  ...  e aim of the present study was to assess arterial and specifically carotid stiffness indices and the correlation of the latter with cerebrovascular events.  ... 
doi:10.1159/000363090 pmid:24820383 fatcat:klgzz6jqb5cw7apjjr4mzpcjjy

A correlative study of homocysteine levels and dementia: an Indian perspective

Roshan Iqbal, S. Harsha, Nemichandra S. C., Shasthara Paneyala, Vimala C. Colaco
2021 International Journal of Research in Medical Sciences  
However, studies correlating the homocysteine levels and severity of dementia in the Indian subcontinent is lacking.  ...  This study is aimed to analyse the diagnostic utility of serum total homocysteine in dementia and to examine the association between serum total homocysteine levels and severity of dementia.Methods: This  ...  strain imaging and cognition assessment conducted on both symptomatic and asymptomatic carotid atherosclerosis patients illustrated that the presence of carotid plaque had a strong relationship with cognitive  ... 
doi:10.18203/2320-6012.ijrms20213077 fatcat:zv3c4qokffe6xlb246z2wgzmjy

Vascular and Endothelial Function in Youth with Type 2 Diabetes Mellitus

Amy S. Shah, Elaine M. Urbina
2017 Current Diabetes Reports  
Purpose of Review-This review aims to discuss the burden of type 2 diabetes in youth and summarize the studies that have utilized noninvasive techniques to assess early vascular disease in youth with type  ...  Future studies need to address treatments that have the potential to improve or reverse vascular dysfunction and decrease the rate of cardiovascular disease and complications.  ...  In 2010, the cost of care for diabetes and its complications in the USA was estimated to be greater than $316 billion per year and continues to rise [11] .  ... 
doi:10.1007/s11892-017-0869-0 pmid:28432570 pmcid:PMC5800521 fatcat:yyh3wodjpvb3rdwfjoq26czjye

Ethnic differences in carotid artery diameter and stiffness: The Northern Manhattan Study

Matthew S. Markert, David Della-Morte, Digna Cabral, Eugene L. Roberts, Hannah Gardener, Chuanhui Dong, Clinton B. Wright, Mitchell S.V. Elkind, Ralph L. Sacco, Tatjana Rundek
2011 Atherosclerosis  
Our objective was to investigate differences in carotid artery diameter and stiffness between race/ethnic groups, and examine whether these race/ethnic differences were agedependent.  ...  We used multivariable linear regression models to determine the relationship between race/ethnicity and both carotid arterial stiffness and carotid diastolic diameter.  ...  We noted the presence of carotid plaque in any of the carotid segments and recorded the number of plaques in each segment.  ... 
doi:10.1016/j.atherosclerosis.2011.08.028 pmid:21906739 pmcid:PMC3226921 fatcat:bo4vmvqktzcfzn2edmrxeuucsm

Ultrasonographic vascular mechanics to assess arterial stiffness: a review

Rogério Teixeira, Maria João Vieira, Alexandra Gonçalves, Nuno Cardim, Lino Gonçalves
2015 European Heart Journal-Cardiovascular Imaging  
In the course of this review, we describe fundamental concepts and methodologies involved in ultrasound assessment of vascular mechanics.  ...  Local arterial stiffness may be gauged via ultrasound, measuring pulse transit time relative to changing vessel diameters and distending pressures.  ...  Conflict of interest: none declared.  ... 
doi:10.1093/ehjci/jev287 pmid:26546802 fatcat:fnp5agbelnbflpguq4nagzzhv4
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