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Biomedical Informatics for Computer-Aided Decision Support Systems: A Survey

Ashwin Belle, Mark A. Kon, Kayvan Najarian
2013 The Scientific World Journal  
This paper provides a brief review of such systems, their application protocols and methodologies, and the future challenges and directions they suggest.  ...  The design, implementation, and use of biomedical informatics systems in the form of computer-aided decision support have become essential and widely used over the last two decades.  ...  e �rst system is an image-based risk score algorithm for predicting the outcome of the estrogen receptor marker for breast cancer patients based on digitized biopsy.  ... 
doi:10.1155/2013/769639 pmid:23431259 pmcid:PMC3575619 fatcat:ryiuxkmx3fhspnfdswfutqp5oq

Prediction of imminent, severe deterioration of children with parallel circulations using real-time processing of physiologic data

Craig G. Rusin, Sebastian I. Acosta, Lara S. Shekerdemian, Eric L. Vu, Aarti C. Bavare, Risa B. Myers, Lance W. Patterson, Ken M. Brady, Daniel J. Penny
2016 Journal of Thoracic and Cardiovascular Surgery  
their early neonatal palliation and stage 2 surgical palliation.  ...  The algorithm was optimized to discriminate pre-deterioration physiology from stable physiology. Results-Twenty cardiorespiratory deterioration events were identified in 13 of the 25 infants.  ...  of the National Institute of Health under Award U10HL068270 and the Rice University National Library of Medicine Training Program in Biomedical Informatics through the Keck Center of the Gulf Coast Consortia  ... 
doi:10.1016/j.jtcvs.2016.03.083 pmid:27174513 pmcid:PMC4921264 fatcat:vv4annpjfvh7pbilbi2hpxshbe

Application of signal processing techniques in the assessment of clinical risks in preterm infants [article]

Ying Zhang
2014 arXiv   pre-print
Preterm infants with very low birth weight suffer from a high risk of intra-ventricular hemorrhage(IVH) and other serious diseases.  ...  The combination of signal analysis and multivariate regression model in estimation of CO has produced some outcomes, and in the future, more effort should be involved in this kind of research to improve  ...  The suggestions above are examples of possible future research based on the results presented in this paper.  ... 
arXiv:1404.5725v1 fatcat:aoak6t5h5bfh7lpf4ru4yy7aaa

Critical care, Emergency medicine, Blood gases, POCT

2017 Clinical Chemistry and Laboratory Medicine  
Finally, before the insertion of new devices, a discussion included the direction of the department, direction of the laboratory department and the direction of the biomedical engineering unit is conducted  ...  training program supervised by the laboratory department.  ...  A quick determination of creatinine by a POC device would facilitate the analysis.  ... 
doi:10.1515/cclm-2017-5016 fatcat:vlm36vdckbeorghnxag2swebui

Designing optimal mortality risk prediction scores that preserve clinical knowledge

Natalia M. Arzeno, Karla A. Lawson, Sarah V. Duzinski, Haris Vikalo
2015 Journal of Biomedical Informatics  
To this end, we propose a novel score structure that relies on a transformation of predictive variables by means of nonlinear logistic functions facilitating smooth differentiation between critical and  ...  Many in-hospital mortality risk prediction scores dichotomize predictive variables to simplify the score calculation.  ...  Acknowledgments The authors would like to thank Karen Piper for the identification of patients that met the inclusion criteria for the study.  ... 
doi:10.1016/j.jbi.2015.05.021 pmid:26056073 fatcat:jbaixw7wo5am7h4c765d7zhm5q

Machine learning in critical care: state-of-the-art and a sepsis case study

Alfredo Vellido, Vicent Ribas, Carles Morales, Adolfo Ruiz Sanmartín, Juan Carlos Ruiz Rodríguez
2018 BioMedical Engineering OnLine  
The second goal is presenting a collection of results that illustrate the breath of possibilities opened by ML and CI methods using a single problem, the investigation of septic shock at the ICU.  ...  The current study has a dual goal: it is first a review of the state-of-the-art on the use and application of such methods in the field of critical care.  ...  Support Vector Regression for the automated estimation of birth gestational age of neonates.  ... 
doi:10.1186/s12938-018-0569-2 pmid:30458795 pmcid:PMC6245501 fatcat:g6pdswcqwvd5bg3svjtlarvgsi

Abstracts of the 25th European Workshop on Neonatology, Westerburg Castle, Germany, May 28th – 31st, 2017

2017 Journal of Neonatal-Perinatal Medicine  
Congenital malformations carry the risk of recurrence in following pregnancies besides the effect on life span and quality.  ...  The most common single malformation was a neural tube defect.  ...  Discrimination and memory in the rabbit seem to depend on litter size. CARDIOVASCULAR RISK PROFILE IN FORMER VERY PRETERM INFANTS AT A PRESCHOOL AGE U. Kiechl-Kohlendorfer 1 , A.  ... 
doi:10.3233/npm-990003 pmid:28453494 fatcat:crwwjlcjubeflbces6todjiz74

Development of a biophysical screening model for gestational hypertensive diseases

Sharona Vonck, Anneleen S. Staelens, Dorien Lanssens, Kathleen Tomsin, Jolien Oben, Liesbeth Bruckers, Wilfried Gyselaers
2019 Journal of Biomedical Science  
Preliminary prediction models were developed to test the screening potential for early preeclampsia, late preeclampsia and gestational hypertension using a Partial Least Square Discriminant Analysis.  ...  Results: A combined model using maternal characteristics with cardiovascular parameters in first and second trimester offers high screening performance with Area Under the Curve of 99,9% for Early-onset  ...  Funding The first author of this work is funded by a Ph.D. grant of the Agency for Innovation by Science and Technology (IWT) in Brussels, Belgium.  ... 
doi:10.1186/s12929-019-0530-0 fatcat:cuocy4lnhbe4vft7juk2ak257q

An Analysis of Medical Informatics and Application of Computer-Aided Decision Support Framework

Yun Chen, Ernst Ginell
2020 Journal of Medical and Image Computing  
The paper ends with the analysis of the future problems and directions of the CAD support framework.  ...  Due to the advent of technology in the medical sector, the future of the Computer-Aided Decision (CAD) is promising as a support system for the processing of images.  ...  The initial system is image-centred risks score algorithms for the outcome projection of oestrogen receptors markers for patients suffering from breast cancer.  ... 
doi:10.46532/jmic.20200702 fatcat:yqxpxnzn65cqhoyailxmbwdvxe

Use of Racial and Ethnic Categories in Medical Testing and Diagnosis: Primum Non Nocere

Jay S Kaufman, Joanna Merckx, Richard S Cooper
2021 Clinical Chemistry  
We then critique these uses along a number of different dimensions, including limitations in measurement, within- versus between-group variance, and implications for informativeness of risk markers for  ...  Summary Medicine has evolved from a mystical healing art to a mature science of human health through a rigorous process of quantification, experimentation, and evaluation.  ...  By the 21st century they were as a group more prone to obesity and all major cardiovascular disease outcomes. To take a more Fig. 2 .  ... 
doi:10.1093/clinchem/hvab164 pmid:34557889 fatcat:yfvonxjq7bh5rp5ndrgnzavnca

Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Xindi Yu, Maolin Chen, Xu Liu, Yiwei Chen, Zedong Hao, Haibo Zhang, Wei Wang
2020 BMC Infectious Diseases  
The baseline characteristics of these patients of different ages, including neonates (0-1 months old), infants (1-12 months old) and children (1-10 years old), were analyzed, and the association of risk  ...  A total of 11,651 subjects were included in the study. The overall nosocomial infection rate was 10.8%.  ...  ., Ltd. for providing a data analysis and statistical platform.  ... 
doi:10.1186/s12879-020-4769-6 pmid:31964345 fatcat:fjqvcovognc5tjtvwacvzqkjre

Coupling between mean blood pressure and EEG in preterm neonates is associated with reduced illness severity scores

Oksana Semenova, Gordon Lightbody, John M. O'Toole, Geraldine Boylan, Eugene Dempsey, Andriy Temko, Gaetano Valenza
2018 PLoS ONE  
The illness severity was represented by the clinical risk index for babies (CRIB II score) and contrasted to the computed level of interaction.  ...  The obtained results allow us to hypothesise that the normal wellbeing of a preterm neonate can be characterised by a nonlinear coupling between brain activity and MAP, whereas the presence of weak coupling  ...  Acknowledgments The authors would like to thank Rhodri Lloyd for his assistance in the preparation of the database of preterm physiological recordings.  ... 
doi:10.1371/journal.pone.0199587 pmid:29933403 pmcid:PMC6014641 fatcat:yv5t5sqrjvbzthsbn4umbcgwpe

Adjusting for Risk Associated with Pediatric and Congenital Cardiac Catheterization: A Report from the NCDR® IMPACTTMRegistry

Natalie Jayaram, Robert H. Beekman, Lee Benson, Ralf Holzer, Kathy Jenkins, Kevin F. Kennedy, Gerard R. Martin, John W. Moore, Richard Ringel, Jonathan Rome, John A. Spertus, Robert Vincent (+1 others)
2015 Circulation  
Dr Beekman serves as a proctor for Amplatzer Occluder Devices for St. Jude Medical, Inc. Dr Bergersen is a consultant for 480 Biomedical. The other authors report no conflicts.  ...  He serves as a paid editor for Circulation: Cardiovascular Quality and Outcomes and has intellectual property rights for the Seattle Angina Questionnaire, Kansas City Cardiomyopathy Questionnaire, and  ...  For the purposes of this analysis, rather than creating a composite score and categorizing patients on the basis of the number of hemodynamic variables present (0, 1, ≥2), as was done in the original CHARM  ... 
doi:10.1161/circulationaha.114.014694 pmid:26481778 pmcid:PMC4787531 fatcat:mfnqr7skq5a75e5l3q6zkknmje

Is model of care associated with infant birth outcomes among vulnerable women? A scoping review of midwifery-led versus physician-led care

Daphne N. McRae, Nazeem Muhajarine, Kathrin Stoll, Maureen Mayhew, Saraswathi Vedam, Deborah Mpofu, Patricia A. Janssen
2016 SSM: Population Health  
And, a third study reported a decrease in stays (1-3 days) in NICU (Adjusted Risk Difference¼ À1.8, 95% CI: À 3.9, 0.2) for midwifery patients, though no overall difference in NICU admission of any duration  ...  No study reported a statistically significant difference for small for gestational age birth (2 studies), or mean or low Apgar score (4 studies).  ...  birth centre midwifery eligibility (Benatar et al., 2013; Jackson et al., 2003) ; (b) a previously developed scale and risk scoring conducted by public health nurses (Heins et al., 1990) ; and (c) by  ... 
doi:10.1016/j.ssmph.2016.01.007 pmid:29349139 pmcid:PMC5757823 fatcat:qwewnrldefeitgv3gcjhqf6vgm

Stress-Induced Inflammatory Responses in Women

Lisa M. Christian, Ronald Glaser, Kyle Porter, Jay D. Iams
2013 Psychosomatic Medicine  
Inflammation is a key biological pathway by which stress may affect birth outcomes. This study examined the effects of race and pregnancy on stress-induced inflammatory responses.  ...  Discrimination Scale; MSPSS = Multidimensional Scale of Perceived Social Support; AUC = area under the curve.  ...  A score higher than 5 is indicative of clinically disturbed sleep. The EOD is a nine-item measure assessing the occurrence and frequency of discrimination caused by race/ethnicity.  ... 
doi:10.1097/psy.0b013e31829bbc89 pmid:23873713 pmcid:PMC3788648 fatcat:yj6543nryzcd5hwjsujvfarfci
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