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Validation of Intramural Wavefront Reconstruction and Estimation of 3D Conduction Velocity

Wilson Good, Karli Gillette, Jake Bergquist, Brian Zenger, Jess Tate, Gernot Plank, Rob MacLeod
<span title="2019-12-30">2019</span> <i title="Computing in Cardiology"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vphume4ntvdthh5cau63f4hnw4" style="color: black;">2019 Computing in Cardiology Conference (CinC)</a> </i> &nbsp;
This study used simulated datasets to validate our methods for reconstructing 3D activation fronts and estimating conduction velocities.  ...  Changes in conduction velocity are indicative of a wide variety of cardiac abnormalities yet measuring conduction velocity is challenging, especially within the myocardial volume.  ...  Methods Wavefront Reconstruction and Estimation of 3D Conduction Velocity This study used intramural plunge needles, replicating the experimental placement and density, to approximate the conduction  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.22489/cinc.2019.420">doi:10.22489/cinc.2019.420</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32123687">pmid:32123687</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7051050/">pmcid:PMC7051050</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/baaljztltzf2xguhz7ly6e46bu">fatcat:baaljztltzf2xguhz7ly6e46bu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200430210725/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7051050&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e8/ec/e8ec796830fe6872db8b93561ca4c2d9f45b2a6b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.22489/cinc.2019.420"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051050" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Fusion of optical imaging and MRI for the evaluation and adjustment of macroscopic models of cardiac electrophysiology: A feasibility study

Mihaela Pop, Maxime Sermesant, Damien Lepiller, Michael V. Truong, Elliot R. McVeigh, Eugene Crystal, Alexander Dick, Herve Delingette, Nicholas Ayache, Graham A. Wright
<span title="">2009</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kpkfymbkufcnzjfc5ydyokby4y" style="color: black;">Medical Image Analysis</a> </i> &nbsp;
There was good agreement between model behaviour and experiment using fusion of optical and MR data, and model parameters from previous work in the literature.  ...  A secondary goal was to use one of these studies to demonstrate an optimized method for regional adjustment of critical model parameters (i.e., adjustment of the local conductivity from the isochronal  ...  Mihaela Pop was supported by a Ph.D. scholarship from the Heart and Stroke Foundation of Canada.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.media.2008.07.002">doi:10.1016/j.media.2008.07.002</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18768344">pmid:18768344</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jk64xu7kjrcmhbjoogicn5tk5m">fatcat:jk64xu7kjrcmhbjoogicn5tk5m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170808211703/http://www-sop.inria.fr/asclepios/Publications/Maxime.Sermesant/MEDIA2008Pop.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5b/98/5b9832bdfe2bbc2a94e1fde73a185f807baa471c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.media.2008.07.002"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Inter-model consistency and complementarity: Learning from ex-vivo imaging and electrophysiological data towards an integrated understanding of cardiac physiology

O. Camara, M. Sermesant, P. Lamata, L. Wang, M. Pop, J. Relan, M. De Craene, H. Delingette, H. Liu, S. Niederer, A. Pashaei, G. Plank (+9 others)
<span title="">2011</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/r3iw4i7vsvg3baci7ij2v5osfu" style="color: black;">Progress in Biophysics and Molecular Biology</a> </i> &nbsp;
This data was used to develop and customize four models of cardiac electrophysiology with different level of details, including a personalized fast conduction Purkinje system, a maximum a posteriori estimation  ...  Computational models of the heart at various scales and levels of complexity have been independently developed, parameterised and validated using a wide range of experimental data for over four decades  ...  , conductivity parameter value homogenization or use of volumetric ground-truth data.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.pbiomolbio.2011.07.007">doi:10.1016/j.pbiomolbio.2011.07.007</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21791225">pmid:21791225</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2d255d3ucfdlpbfwl2lyxfqmga">fatcat:2d255d3ucfdlpbfwl2lyxfqmga</a> </span>
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Techniques for automated local activation time annotation and conduction velocity estimation in cardiac mapping

C.D. Cantwell, C.H. Roney, F.S. Ng, J.H. Siggers, S.J. Sherwin, N.S. Peters
<span title="">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wdwg5aetkjbgpga7kn2jevifmi" style="color: black;">Computers in Biology and Medicine</a> </i> &nbsp;
Measurements of cardiac conduction velocity provide valuable functional and structural insight into the initiation and perpetuation of cardiac arrhythmias, in both a clinical and laboratory context.  ...  However, the sparsity, distribution and uncertainty of recorded data make accurate conduction velocity calculation difficult.  ...  The conduction velocity is then estimated as r=A. Initial validation of the method was provided through simulated data [82] .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.compbiomed.2015.04.027">doi:10.1016/j.compbiomed.2015.04.027</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25978869">pmid:25978869</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4593301/">pmcid:PMC4593301</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jmrewunyyneubmmn2nycvrex2y">fatcat:jmrewunyyneubmmn2nycvrex2y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809105914/https://spiral.imperial.ac.uk:8443/bitstream/10044/1/24088/2/Cantwell_Techniques%20for%20automated.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/06/69/06699406cc3b0a513683be2ecdc2e96df2f20691.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.compbiomed.2015.04.027"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593301" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Muscle Thickness and Curvature Influence Atrial Conduction Velocities

Simone Rossi, Stephen Gaeta, Boyce E Griffith, Craig S Henriquez
<span title="2018-10-29">2018</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/evju7ot335gbrctgmomg4gg6je" style="color: black;">Frontiers in Physiology</a> </i> &nbsp;
We further demonstrate that the conclusions drawn from the idealized test case can be used to explain spatial changes in conduction velocities in a patient-specific reconstruction of the left atrial posterior  ...  In this work, we show how endocardial conduction velocities are also affected by the geometrical factors of muscle thickness and wall curvature.  ...  ACKNOWLEDGMENTS We gratefully acknowledge support by the libMesh developers in aiding the development of the code used in the simulations reported herein.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fphys.2018.01344">doi:10.3389/fphys.2018.01344</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30420809">pmid:30420809</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6215968/">pmcid:PMC6215968</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7qobzlgdwbdwppaaab5obm34cq">fatcat:7qobzlgdwbdwppaaab5obm34cq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200209205116/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6215968&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e6/11/e611e541f431007772245c38049cfb8b848012dc.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fphys.2018.01344"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215968" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Model-Based Imaging of Cardiac Apparent Conductivity and Local Conduction Velocity for Diagnosis and Planning of Therapy

Phani Chinchapatnam, Kawal S. Rhode, Matthew Ginks, C. Aldo Rinaldi, Pier Lambiase, Reza Razavi, Simon Arridge, Maxime Sermesant
<span title="">2008</span> <i title="Institute of Electrical and Electronics Engineers (IEEE)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/yhnt2pif75h2bmnnmdg7m6nlc4" style="color: black;">IEEE Transactions on Medical Imaging</a> </i> &nbsp;
We present an adaptive algorithm which uses a fast electrophysiological (EP) model to estimate apparent electrical conductivity and local conduction velocity from non-contact mapping of the endocardial  ...  The proposed model is validated on synthetic data and applied to clinical data derived using hybrid X-ray/magnetic resonance imaging.  ...  ACKNOWLEDGEMENTS The authors would like to acknowledge Steven Sinclair, research radiographer at the Division of Imaging Sciences and Julian Bostock and cardiac technicians at Guy's and St.Thomas' NHS  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1109/tmi.2008.2004644">doi:10.1109/tmi.2008.2004644</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18955178">pmid:18955178</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wlg63jnspfgr3erhccv6dpdvv4">fatcat:wlg63jnspfgr3erhccv6dpdvv4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170808211645/http://www-sop.inria.fr/asclepios/Publications/Maxime.Sermesant/TMI2008Phani.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e0/d5/e0d5d8c9153f06d65e545acc280ffd54907d683a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1109/tmi.2008.2004644"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> ieee.com </button> </a>

Construction of 3D MR image-based computer models of pathologic hearts, augmented with histology and optical fluorescence imaging to characterize action potential propagation

Mihaela Pop, Maxime Sermesant, Garry Liu, Jatin Relan, Tommaso Mansi, Alan Soong, Jean-Marc Peyrat, Michael V. Truong, Paul Fefer, Elliot R. McVeigh, Herve Delingette, Alexander J. Dick (+2 others)
<span title="">2012</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kpkfymbkufcnzjfc5ydyokby4y" style="color: black;">Medical Image Analysis</a> </i> &nbsp;
The specific goals of this paper were to match models with maps of the propagation of optical AP on the epicardial surface using large porcine hearts with scars, estimating several parameters relevant  ...  Cardiac computer models can help us understand and predict the propagation of excitation waves (i.e., action potential, AP) in healthy and pathologic hearts.  ...  Mihaela Pop was supported by a research award from Heart and Stroke Foundation of Canada, and an OGSST scholarship.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.media.2011.11.007">doi:10.1016/j.media.2011.11.007</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22209561">pmid:22209561</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4tpzhnuj6naf5jvf6w53lchabq">fatcat:4tpzhnuj6naf5jvf6w53lchabq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809125725/http://www-sop.inria.fr/asclepios/Publications/Maxime.Sermesant/MedIA_Mihaela2012.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/63/2c/632c9aad0d596de4dcbe0200bbee89050b524a05.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.media.2011.11.007"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations

Tobias Bruegmann, Patrick M. Boyle, Christoph C. Vogt, Thomas V. Karathanos, Hermenegild J. Arevalo, Bernd K. Fleischmann, Natalia A. Trayanova, Philipp Sasse
<span title="2016-09-12">2016</span> <i title="American Society for Clinical Investigation"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3toa7g22uzexljesj5ehm7x7da" style="color: black;">Journal of Clinical Investigation</a> </i> &nbsp;
Holst for technical assistance and Penn Vector Core, Gene Therapy Program (University of Pennsylvania), for providing the AAV9-CAG-hChR2(H134R)-mCherry. WPRE  ...  Electrophysiology of normal and diseased human cardiac tissue was represented using an extensively validated approach (35) .  ...  These points were used as input data for previously described interpolation software, which was used to recreate a 3D rendering of the cardiac surfaces.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1172/jci88950">doi:10.1172/jci88950</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27617859">pmid:27617859</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5096832/">pmcid:PMC5096832</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jpelk2csf5fmxavx2fuatgvt24">fatcat:jpelk2csf5fmxavx2fuatgvt24</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190224212608/http://pdfs.semanticscholar.org/5b79/3a0b10e4ab66c4f9bc0c569196c5e1b8e790.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5b/79/5b793a0b10e4ab66c4f9bc0c569196c5e1b8e790.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1172/jci88950"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096832" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models

Hermenegild J. Arevalo, Fijoy Vadakkumpadan, Eliseo Guallar, Alexander Jebb, Peter Malamas, Katherine C. Wu, Natalia A. Trayanova
<span title="2016-05-10">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a4wan6l5o5dfzn767kyz7jqevi" style="color: black;">Nature Communications</a> </i> &nbsp;
We construct personalized three-dimensional computer models of post-infarction hearts from patients' clinical magnetic resonance imaging data and assess the propensity of each model to develop arrhythmia  ...  Here, we develop a personalized approach to assess SCD risk in post-infarction patients based on cardiac imaging and computational modelling.  ...  Acknowledgements This work was supported by NIH Pioneer Award (DP1-HL123271 to NAT), American Heart Association grant (13SDG14510061 to FV), WW Smith Charitable Trust Heart Research grant (H1202 to FV), and  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/ncomms11437">doi:10.1038/ncomms11437</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27164184">pmid:27164184</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4866040/">pmcid:PMC4866040</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6fcyz4lsw5hbhle4lpen3w4uj4">fatcat:6fcyz4lsw5hbhle4lpen3w4uj4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200316153150/https://www.nature.com/articles/ncomms11437.pdf?error=cookies_not_supported&amp;code=3ff1fa77-7d4b-407f-bfc8-28428611a247" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5a/8d/5a8d39347ce0a0a214d6fde2f1046b59577adfb3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/ncomms11437"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> nature.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866040" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Cardiovascular magnetic resonance imaging in the prospective, population-based, Hamburg City Health cohort study: objectives and design

Sebastian Bohnen, Maxim Avanesov, Annika Jagodzinski, Renate B Schnabel, Tanja Zeller, Mahir Karakas, Jan Schneider, Enver Tahir, Ersin Cavus, Clemens Spink, Ulf K Radunski, Francisco Ojeda (+4 others)
<span title="2018-09-24">2018</span> <i title="Springer (Biomed Central Ltd.)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/jflzecjifjfnzmksqbreqnmoo4" style="color: black;">Journal of Cardiovascular Magnetic Resonance</a> </i> &nbsp;
The workflow of CMR data acquisition and analyses was evaluated in a pilot cohort of 200 unselected subjects.  ...  The HCHS database will facilitate combined analyses of imaging, clinical and molecular data ("Radiomics").  ...  Availability of data and materials The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12968-018-0490-7">doi:10.1186/s12968-018-0490-7</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30244673">pmid:30244673</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6151919/">pmcid:PMC6151919</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zi6lpfzxxjewbgi2a26b2bzi3y">fatcat:zi6lpfzxxjewbgi2a26b2bzi3y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190228045831/http://pdfs.semanticscholar.org/9ca7/831f6bb5838f9a3d6c0ecc8af311db12ddc7.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/9c/a7/9ca7831f6bb5838f9a3d6c0ecc8af311db12ddc7.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12968-018-0490-7"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151919" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Toward Patient-Specific Myocardial Models of the Heart

Maxime Sermesant, Jean-Marc Peyrat, Phani Chinchapatnam, Florence Billet, Tommaso Mansi, Kawal Rhode, Hervé Delingette, Reza Razavi, Nicholas Ayache
<span title="">2008</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/akitrmdgfjejnpfnmxc4oqalrq" style="color: black;">Heart Failure Clinics</a> </i> &nbsp;
These conduction velocity maps can aid in determining possible scars, as they show up as areas of low conduction velocity on these velocity maps.  ...  D is the square of the membrane space constant and thus related to the volumetric electrical conductivity of the tissue.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.hfc.2008.02.014">doi:10.1016/j.hfc.2008.02.014</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18598981">pmid:18598981</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dnip3kqe4rd55gkrp4anhj6mum">fatcat:dnip3kqe4rd55gkrp4anhj6mum</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170705103546/http://www-sop.inria.fr/asclepios/Publications/Maxime.Sermesant/HFC2008Sermesant.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/40/06/4006d97981ac68aad1ceed73994e0552beb7860e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.hfc.2008.02.014"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Extracting three-dimensional orientation and tractography of myofibers using optical coherence tomography

Yu Gan, Christine P. Fleming
<span title="2013-09-13">2013</span> <i title="The Optical Society"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/fxa4hwkh5vf4nejqcsg3pblm5u" style="color: black;">Biomedical Optics Express</a> </i> &nbsp;
Prior to image processing, three-dimensional image data set were acquired from all cardiac chambers and ventricular septum of swine hearts using OCT system without optical clearing.  ...  To extract fiber information, we present a method of quantifying fiber orientation and reconstructing three-dimensional tractography of myofibers using optical coherence tomography (OCT).  ...  The research was funded in part by the National Institute of Health and National Heart, Blood and Lung Institute Clinical Loan Repayment Program (CPF) and Columbia University's provost grant program for  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1364/boe.4.002150">doi:10.1364/boe.4.002150</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24156071">pmid:24156071</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3799673/">pmcid:PMC3799673</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6rpf4rnwbzdlvhmlafibcigeae">fatcat:6rpf4rnwbzdlvhmlafibcigeae</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20181102002308/https://academiccommons.columbia.edu/doi/10.7916/D8VT2359/download" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8b/3a/8b3aa776dad291ac82167c500009212e1e718d68.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1364/boe.4.002150"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799673" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Reducing Line-of-block Artifacts in Cardiac Activation Maps Estimated Using ECG Imaging: A Comparison of Source Models and Estimation Methods [article]

Steffen Schuler, Matthias Schaufelberger, Laura R. Bear, Jake A. Bergquist, Matthijs J. M. Cluitmans, Jaume Coll-Font, Önder N. Onak, Brian Zenger, Axel Loewe, Rob S. MacLeod, Dana H. Brooks, Olaf Dössel
<span title="2021-08-18">2021</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Objective: To investigate cardiac activation maps estimated using electrocardiographic imaging and to find methods reducing line-of-block (LoB) artifacts, while preserving real LoBs.  ...  From these, activation times (AT) were estimated using four methods and compared to the ground truth. This process was evaluated with two cardiac mesh resolutions.  ...  Activation Time Estimation Several methods have been proposed for the estimation of ATs from cardiac mapping data [39] .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2108.06602v2">arXiv:2108.06602v2</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4hejk3kgfzhybp3jpm6yfwsxre">fatcat:4hejk3kgfzhybp3jpm6yfwsxre</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210901010006/https://arxiv.org/pdf/2108.06602v2.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b5/fe/b5fe5fd344e7b9fca1b3d30a07524650c7824bf3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2108.06602v2" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

Understanding AF Mechanisms Through Computational Modelling and Simulations

Konstantinos N Aronis, Rheeda L Ali, Jialiu A Liang, Shijie Zhou, Natalia A Trayanova, Department of Biomedical Engineering and the Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, US, Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD, US, Department of Biomedical Engineering and the Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, US, Department of Biomedical Engineering and the Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, US, Department of Biomedical Engineering and the Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, US, Department of Biomedical Engineering and the Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, US
<span title="2019-08-09">2019</span> <i title="Radcliffe Group Ltd"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4nmehpxqk5a7jfjtws6lvsnbh4" style="color: black;">Arrhythmia &amp; Electrophysiology Review</a> </i> &nbsp;
; development of repolarisation alternans; cardiac ion channel mutations; and atrial stretch with mechano-electrical feedback.  ...  Computational modelling provides a framework for integration of experimental and clinical findings, and has emerged as an essential part of mechanistic research in AF.  ...  models using fibre orientation atlases derived from histology, rule-based methods or methods that use morphological data of the endo-and epicardial surfaces and the local solutions of Laplace's equations  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.15420/aer.2019.28.2">doi:10.15420/aer.2019.28.2</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31463059">pmid:31463059</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6702471/">pmcid:PMC6702471</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/vy6uz6w67nfndegdmh3mkzgyyq">fatcat:vy6uz6w67nfndegdmh3mkzgyyq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200211145408/https://www.aerjournal.com/system/files/articles/AER-8_3_210-19.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/40/29/402924ab40c903728ad23f9e6ebf2bf27a0a7560.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.15420/aer.2019.28.2"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702471" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Computationally guided personalized targeted ablation of persistent atrial fibrillation

Patrick M. Boyle, Tarek Zghaib, Sohail Zahid, Rheeda L. Ali, Dongdong Deng, William H. Franceschi, Joe B. Hakim, Michael J. Murphy, Adityo Prakosa, Stefan L. Zimmerman, Hiroshi Ashikaga, Joseph E. Marine (+5 others)
<span title="2019-08-19">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/i6usv5wcpfd55mv6qejadcmmaq" style="color: black;">Nature Biomedical Engineering</a> </i> &nbsp;
Here, we present personalized computational modelling for the reliable predetermination of ablation targets, which are then used to guide the ablation procedure in patients with persistent AF and atrial  ...  The computational prediction of ablation targets avoids lengthy electrical mapping and could improve the accuracy and efficacy of targeted AF ablation in patients while eliminating the need for repeat  ...  Chiaramonte Foundation; Marilyn and Christian Poindexter; and the Norbert and Louise Grunwald Cardiac Arrhythmia Research Fund.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41551-019-0437-9">doi:10.1038/s41551-019-0437-9</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31427780">pmid:31427780</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6842421/">pmcid:PMC6842421</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/eh7bjom22bc7fnqxhwxkw4vwqy">fatcat:eh7bjom22bc7fnqxhwxkw4vwqy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200501140526/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6842421&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/1b/f9/1bf98f1379429d05813820482baf8eb0fed0f53f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41551-019-0437-9"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> nature.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842421" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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