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Machine Learning Approach for Postprandial Blood Glucose Prediction in Gestational Diabetes Mellitus

Evgenii A. Pustozerov, Aleksandra S. Tkachuk, Elena A. Vasukova, Anna D. Anopova, Maria A. Kokina, Inga V. Gorelova, Tatiana M. Pervunina, Elena N. Grineva, Polina V. Popova
2020 IEEE Access  
The authors are grateful for the valuable comments and suggestions of the reviewers.  ...  ACKNOWLEDGMENTS The authors thank Anna Anopova, Aleksandra Dronova, Ekaterina Vasilieva, Elena Vasilieva and Faina Piven for their help in collecting the clinical data.  ...  ovary syndrome».  ... 
doi:10.1109/access.2020.3042483 fatcat:dmvqucfi2rdgxjz7givsllxfpa

Machine Learning Tools for Long-term Type 2 Diabetes Risk Prediction

Nikos Fazakis, Otilia Kocsis, Elias Dritsas, Sotiris Alexiou, Nikos Fakotakis, Konstantinos Moustakas
2021 IEEE Access  
condition that may occur during pregnancy, raises a women's chances of getting type 2 diabetes later in life. • Polycystic ovary syndrome (PCOS): women with polycystic ovary syndrome have a higher risk  ...  Hence, predictive analytics, machine learning and data mining approaches in T2DM are of major concern when it comes to diagnosis, management and other related clinical aspects.  ... 
doi:10.1109/access.2021.3098691 fatcat:5unb53goqbfijcqk2t5hczyari

Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)

Hannah K. Drescher, Sabine Weiskirchen, Ralf Weiskirchen
2019 Cells  
Another important problem associated with NASH is that presently the liver biopsy is still the gold standard in diagnosis and for disease staging and grading.  ...  Because of its invasiveness, this technique is not well accepted by patients and the method is prone to sampling error.  ...  Some other conditions associated with metabolic syndrome that can lead to NAFLD are the obstructive sleep apnea syndrome (OSAS), polycystic ovary syndrome (PCOS), and non-obese NAFLD.  ... 
doi:10.3390/cells8080845 pmid:31394730 pmcid:PMC6721710 fatcat:v7xztzqo6zblrg4hjwwgphmxai

Nonalcoholic Fatty Liver Disease (NAFLD): Pathogenesis and Noninvasive Diagnosis

Vicneswarry Dorairaj, Siti Aishah Sulaiman, Nadiah Abu, Nor Azian Abdul Murad
2021 Biomedicines  
There is thus an increased need to find alternative techniques or tools for accurate diagnosis.  ...  Although a liver biopsy remains the gold standard for accurate detection of this condition, it is unsuitable for clinical screening due to a higher risk of death.  ...  ; NFS: NAFLD fibrosis score; NAFLD-LFS: NAFLD liver fat score; NASH: nonalcoholic steatohepatitis; oxoODE: oxo-octadecadenoic acids; PCOS: polycystic ovary syndrome; PE40:6: phosphoethanolamine 40:6; PIIINP  ... 
doi:10.3390/biomedicines10010015 pmid:35052690 pmcid:PMC8773432 fatcat:jzjk5gyfxzakbcl3sa42474tou


2018 Virchows Archiv  
Gene expression data of a subset of EBV+ GCs fitted into the mesenchymal subtype (30 out of 31 genes, 96.8%).  ...  For each case, we retrieved clinical data, pathology results, molecular quality control scores and detailed DNA variants.  ...  84% of laboratories performs revalidations, in 29% even for small protocol changes.  ... 
doi:10.1007/s00428-018-2422-1 pmid:30120593 fatcat:rxb6dv66m5de5ocytkqgtk5cba

Supplementum 249: Abstracts of the annual meeting 2021 of the Swiss Society of Paediatrics

2021 Swiss Medical Weekly  
The authors wish to thank the Zoé4life Association for its financial support. SPN 3 Acknowledgement: Dr Cachat  ...  The main clinical features are near total absence of adipose tissue and muscular hypertrophy, accompanied by hyperphagia, acanthosis nigricans, hepatomegaly /hepatic steatosis and polycystic ovarian syndrome  ...  As a result, triglyceride and insulin levels as well as the sizes of liver, cardiac septum and ovaries normalized.  ... 
doi:10.4414/smw.2021.20546 pmid:34107049 fatcat:6lq44jwh35euzfy7xujwxplpoy

Abstracts from the 53rd European Society of Human Genetics (ESHG) Conference: e-Posters

2020 European Journal of Human Genetics  
R packages were used for statistical analysis. The genotype distributions of all control groups were in HWE.  ...  Resistance to fatigue and muscle stiffness are considered risk factors for ACL injury.  ...  She had distinctive facial features, hypertrichosis on the face and polycystic ovaries. Neither signs of cardiomegaly nor osteochondrodysplasia were observed.  ... 
doi:10.1038/s41431-020-00741-5 pmid:33262486 fatcat:m6by7js7kfbi5ayebbpywf6ppu

Machine Learning Approaches for Type 2 Diabetes Prediction and Care Management [article]

Aloysius Lim, Ashish Singh, Jody Chiam, Carly Eckert, Vikas Kumar, Muhammad Aurangzeb Ahmad, Ankur Teredesai
2021 arXiv   pre-print
In this manuscript we illustrate a Machine Learning (ML) framework for addressing the problem of predicting Type 2 Diabetes Mellitus (T2DM) together with a solution for risk stratification, intervention  ...  Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed  ...  Additionally, patients with type 1 diabetes [121] , gestational diabetes [111] , [116] , a new T2DM diagnosis [120] , a life expectancy of < 1 year [120] , Metformin use due to polycystic ovary syndrome  ... 
arXiv:2104.07820v2 fatcat:lsuazafzlvaeldleabbstge7ru

Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer

Patrycja Nowak-Sliwinska, Leonardo Scapozza, Ariel Ruiz i Altaba
2019 Biochimica et Biophysica Acta. CR. Reviews on Cancer  
As drug efficacy remains the main bottleneck for overall success, we discuss the need for machine-learning computational methods in combination with specific phenotypic studies along with mechanistic studies  ...  The strategy of using existing drugs originally developed for one disease to treat other indications has found success across medical fields.  ...  Metformin, a biguanide derivative used to treat type II diabetes [167] and polycystic ovary-and metabolic syndrome [168] acts through the reduction of basal glucose output via the suppression gluconeogenesis  ... 
doi:10.1016/j.bbcan.2019.04.005 pmid:31034926 pmcid:PMC6528778 fatcat:3natsjihbfaotlih63orrk3nxm

Jubilee Scientific Conference "Medicine of the Future" - 29-31 October 2020 on the occasion of the 75th Anniversary of Medical University of Plovdiv

Mariana Murdzheva, Stefan Kostianev, Victoria Sarafian-Ozanian, Blagoi Marinov, Dyliana Vicheva
2020 Folia Medica  
The authors are entirely responsible for the content of their abstracts.  ...  and Michel Leventhal first described the polycystic ovary syndrome (PCOS).  ...  It has now become clear that the polycystic ovary syndrome is one of the most common endocrinopathies among women of reproductive age.  ... 
doi:10.3897/folmed.63.e60105 fatcat:hqcbgipz6rgphpye4ddr5v23fa

Abstracts from the 52nd European Society of Human Genetics (ESHG) Conference: Oral Presentations

2019 European Journal of Human Genetics  
in aged ovaries.  ...  C25.4 reg2gene: predicting enhancer-gene associations using ensemble learning approaches such as JEME (Cao et al. 2017), FOCS (Hait et al. 2018), GeneHancer (Fishillevich et al. 2017), and EnhancerAtlas  ...  To date, the CUD has found a strong candidate diagnosis for 10 (9%) patients. Each candidate diagnosis is undergoing further functional investigation.  ... 
doi:10.1038/s41431-019-0492-4 fatcat:wuudroxpgfe6vfpv2ddzyr7vhi

Metabolomic Biomarkers for Detection, Prognosis and Identifying Recurrence in Endometrial Cancer

Kelechi Njoku, Caroline J. Sutton, Anthony D. Whetton, Emma J. Crosbie
2020 Metabolites  
Advances in high-throughput technologies have, in recent times, shown promise for biomarker discovery based on genomic, transcriptomic, proteomic and metabolomic platforms.  ...  Metabolic reprogramming is increasingly recognised as one of the defining hallmarks of tumorigenesis.  ...  Several metabolic risk factors are linked to EC pathogenesis including obesity, type II diabetes mellitus, polycystic ovary syndrome and metabolic syndrome [23, 30] .  ... 
doi:10.3390/metabo10080314 pmid:32751940 pmcid:PMC7463916 fatcat:u234bxhjrnfzdpocms5zmgxqxm

ICCIT 2020 Conference Proceedings [Front matter]

2020 2020 23rd International Conference on Computer and Information Technology (ICCIT)  
Bhavani Thuraisingham is the Founders Chair Professor of Computer Science and the  ...  An Efficient Decision Tree Establishment and Performance Analysis with Different Machine Learning Approaches on Polycystic Ovary Syndrome 89 313 Md. 90 319 Marjana Tahmid, Samiul Alam and Mohammad  ...  Ovary Syndrome Aroni Saha Prapty and Tanzim Tamanna Shitu 9:15-9:30 313 Breast Cancer Detection using Deep Neural Network Md.  ... 
doi:10.1109/iccit51783.2020.9392749 fatcat:pz3hf7rsmzbjpe6hxjlu5tmrfq

2020 Western Medical Research Conference

2019 Journal of Investigative Medicine  
Purpose of study Polycystic ovary syndrome (PCOS) affects 6-10% of women and is associated with hepatic steatosis (HS).  ...  Endocrinology and metabolism II 253 METABOLOMIC CHARACTERIZATION OF HEPATIC STEATOSIS IN POLYCYSTIC OVARY SYNDROME 254 Methods used We illustrate the utility of AMON and SCNIC using a dataset (16s  ...  Equivalent data in the neonatal surgical population is lacking, but literature on skin antisepsis for invasive non-surgical procedures in neonatal intensive care units (NICUs) and for prevention of newborn  ... 
doi:10.1136/jim-2019-wmrc fatcat:cw2dtzk5vzc2bmd4wbujao6igm


2021 European Journal of Clinical Investigation  
The newest mitochondrial assays measure more than 50 aspects of mitochondrial function, profiling the rates of metabolism of mitochondrial substrates and the sensitivity of metabolism of these substrates  ...  This presentation will review the technology and show examples of how it can inform basic and advanced cellular studies.  ...  Keywords: Obesity, gender, polycystic ovary syndrome, obesity-induced hypogonadism 55ASM-0292 IS | Microbial Imidazole A.  ... 
doi:10.1111/eci.13567 fatcat:casumfo4afhklgo42swkednpya
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