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Enhancing memory use in Simple Coma: Multiplexed Simple Coma

S. Basu, J. Torrellas
Proceedings 1998 Fourth International Symposium on High-Performance Computer Architecture  
Scalable shared-memory multiprocessors  ...  Josep Torrellas is supported in part by a n NSF Young Investigator Award.  ...  Recall that, in Simple Coma, a line never needs to displace another one in the attraction memory in hardware while, in Multiplexed Simple Coma, this is possible.  ... 
doi:10.1109/hpca.1998.650555 dblp:conf/hpca/BasuT98 fatcat:sqvucs4sfff4lgb4lzvg3n35o4

Coma in thrombotic thrombocytopenic purpura

F. E KELLY, D. F TREACHER, F. M K WILLIAMS, B. J HUNT, R. S HOWARD
1999 Journal of Neurology, Neurosurgery and Psychiatry  
The third section is dedicated to memory and its disorders, with extremely readable overviews of advances and controversies in the neuropsychology of memory and clinical disorders.  ...  Sadly the nearest he got was "The message to the public is simple: the goal is to take the patient to the emergency room as fast as possible using emergency medical transportation and transfer the patient  ... 
doi:10.1136/jnnp.66.5.689 pmid:10348644 pmcid:PMC1736339 fatcat:ncvc6eoplzaunn5eylvzcxss4i

Cache-only memory architectures

F. Dahlgren, J. Torrellas
1999 Computer  
Unlike in a conventional  CC-NUMA architecture, in a COMA, every shared- memory module in the machine is a cache, where each  memory line has a tag with the line's address and state.  As a processor  ...  .  There are three issues that need to be addressed in  COMA, namely finding a line, replacing a line, and deal- ing with the memory overhead.  ...  Dahlgren and Torrellas present a more  in-depth survey of COMA machine issues []. There . Basu S, Torrellas J () Enhancing memory use in simple coma:  multiplexed simple coma.  ... 
doi:10.1109/2.769448 fatcat:ozadfmvoyne5jczmnm42x4ukza

Decoupled hardware support for distributed shared memory

Steven K. Reinhardt, Robert W. Pfile, David A. Wood
1996 SIGARCH Computer Architecture News  
This paper investigates hardware support for fine-grain distributed shared memory (DSM) in networks of workstations.  ...  To demonstrate the feasibility and simplicity of this access control device, we designed and built an FPGA-based version in under one year.  ...  Babak Falsafi and Shubu Mukherjee contributed to the development of the simulator used in this paper. Mark Hill and Jim Larus provided valuable comments on drafts of this paper.  ... 
doi:10.1145/232974.232979 fatcat:xlvt3pco3vakrhow3fr5taaefy

Decoupled hardware support for distributed shared memory

Steven K. Reinhardt, Robert W. Pfile, David A. Wood
1996 Proceedings of the 23rd annual international symposium on Computer architecture - ISCA '96  
This paper investigates hardware support for fine-grain distributed shared memory (DSM) in networks of workstations.  ...  To demonstrate the feasibility and simplicity of this access control device, we designed and built an FPGA-based version in under one year.  ...  Babak Falsafi and Shubu Mukherjee contributed to the development of the simulator used in this paper. Mark Hill and Jim Larus provided valuable comments on drafts of this paper.  ... 
doi:10.1145/232973.232979 dblp:conf/isca/ReinhardtPW96 fatcat:3brtvx2ihjcczkrrqbw7qj6wra

Does the Glasgow Coma Scale correctly diagnose the vegetative and minimally conscious states?

C Schnakers, J Giacino, K Kalmar, S Piret, E Lopez, M Boly, R Malone, S Laureys
2007 Critical Care  
These beneficial effects occurred without any detectable adverse hemodynamic or cardiovascular effects of sulfide at the dose used in the current study.  ...  increase in plasma IL-1β and TNFα levels.  ...  This study investigated the use of an enhanced MPC algorithm (eMPC) in more severely ill patients over 72 hours.  ... 
doi:10.1186/cc5648 fatcat:mfozksemy5gsbfaujoqdyr6rfy

Design of a bus-based shared-memory multiprocessor DICE

Gyungho Lee, Bland W Quattlebaum, Sangyeun Cho, Larry L Kinney
1999 Microprocessors and microsystems  
DICE tries to optimize COMA for a shared-bus medium, in particular to reduce detrimental effects of the cache coherence and the 'last memory block' problem on replacement.  ...  DICE is a shared-bus multiprocessor based on a distributed shared-memory architecture, known as cache-only memory architecture (COMA).  ...  An earlier version of the paper was presented in Ref. [26] .  ... 
doi:10.1016/s0141-9331(98)00097-0 fatcat:gmluftwjg5g3ximidir4rq3b7y

Hardware support for flexible distributed shared memory

S.K. Reinhardt, R.W. Pfile, D.A. Wood
1998 IEEE transactions on computers  
In addition, the custom protocols are generally effective at reducing the impact of other overheads, including those due to less aggressive hardware support and larger network latencies.  ...  (In this and following figures, SC stands for Simple COMA, T for Typhoon, T1 for Typhoon-1, and T0 for Typhoon-0.)  ...  (Typhoon), outperforming the Simple COMA system by nearly the same amount.  ... 
doi:10.1109/12.729790 fatcat:ybyu26st3vbl5mbnytscnzzxlq

From Understanding Cellular Function to Novel Drug Discovery: The Role of Planar Patch-Clamp Array Chip Technology

Christophe Py, Marzia Martina, Gerardo A. Diaz-Quijada, Collin C. Luk, Dolores Martinez, Mike W. Denhoff, Anne Charrier, Tanya Comas, Robert Monette, Anthony Krantis, Naweed I. Syed, Geoffrey A. R. Mealing
2011 Frontiers in Pharmacology  
This work was supported in part by a CIHR grant to NIS. Collin Luk is supported by AIHS and NSERC studentship awards.  ...  extract from multiplexed signals.  ...  to extract from these multiplexed signals.  ... 
doi:10.3389/fphar.2011.00051 pmid:22007170 pmcid:PMC3184600 fatcat:c7sjosypozddrjygzqsxtu2a5y

ESO Spectroscopic Facility

Luca Pasquini, B. Delabre, R. S. Ellis, J. Marrero, L. Cavaller, Tim de Zeeuw
2017 Proceedings of the International Astronomical Union  
AbstractWe present the concept of a novel facility dedicated to massively-multiplexed spectroscopy. The telescope has a very wide field Cassegrain focus optimised for fibre feeding.  ...  The 3 lenses corrector includes an ADC, and has good performance in the 360-1300 nm wavelength range.  ...  The tilt introduces coma, that is corrected by simultaneously translating the secondary. The correction is good up to airmass ∼1.8, and in the 360-1300 nm interval.  ... 
doi:10.1017/s174392131700847x fatcat:g4nvgopfifen5hlija466ptvq4

Psychiatric emergencies (part III): psychiatric symptoms resulting from organic diseases

A Testa, R Giannuzzi, S Daini, L Bernardini, L Petrongolo, N Gentiloni Silveri
2013 European Review for Medical and Pharmacological Sciences  
The role of immune system in influencing the central nervous system, explaining the model of "sickness behaviour" in inflammatory disease, is also described, according to recent reports of "psychoneuroimmunology  ...  Moreover, the immune-mediated mechanism explaining how neoplasm can influence brain function in the "paraneoplastic syndromes" is shown.  ...  delirium and coma.  ... 
pmid:23436670 fatcat:5ejpcyltxrc2ppw7u4hsrs4zxm

Expanded newborn screening and confirmatory follow-up testing for inborn errors of metabolism detected by tandem mass spectrometry

Tomris Ozben
2013 Clinical Chemistry and Laboratory Medicine  
manipulation have allowed the introduction of expanded NBS for the identification of numerous conditions on a single sample and new conditions to be added to the list of disorders being screened for using  ...  The most common confirmatory follow-up tests are amino acids and acylcarnitine analysis in plasma and organic acid analysis in urine. NBS should be integrated with follow-up and clinical management.  ...  In a recent study, a simple and reliable method has been used for the detection of amino acids without derivatization [ 65 ] .  ... 
doi:10.1515/cclm-2012-0472 pmid:23183752 fatcat:h6kcz7zsb5ajres6u272rgjuhq

Global bus design of a bus-based COMA multiprocessor DICE

G. Lee, B. Quattlebaum, S. Cho, L. Kinney
Proceedings International Conference on Computer Design. VLSI in Computers and Processors  
In this paper, we present a global bus design for a bus-based COMA multiprocessor using the IEEE Fu-turebus+ standard backplane bus and the Texas Instruments chip-set.  ...  DICE tries to optimize the COMA for a shared-bus medium, in particular to reduce detrimental effects of the cache coherence and the "last memory block" problem on replacement.  ...  Note that recent high-performance microprocessors support the relaxed memory models [6] . Bus-based COMA multiprocessors A major overhead involved in the COMA is additional extra memory.  ... 
doi:10.1109/iccd.1996.563562 dblp:conf/iccd/LeeQCK96 fatcat:e536jclz4faqriiawhwgxxyz34

Tempest and typhoon

S. K. Reinhardt, J. R. Larus, D. A. Wood
1994 SIGARCH Computer Architecture News  
Today's machines limit these programs to a single communication paradigm, either message-passing or shared-memory, which results in uneven performance.  ...  First, the Stache protocol uses Tempest's finegrain access control mechanisms to manage part of a processor's local memory as a large, fully-associative cache for remote data.  ...  Unlike the extensive, custom hardware in a COMA machine, Stache runs in userlevel software using the Tempest interface.  ... 
doi:10.1145/192007.192062 fatcat:6yffl7imkzhaparrgqihwlzbfu

Tempest and typhoon

Steven K. Reinhardt, James R. Larus, David A. Wood
1998 25 years of the international symposia on Computer architecture (selected papers) - ISCA '98  
Today's machines limit these programs to a single communication paradigm, either message-passing or shared-memory, which results in uneven performance.  ...  First, the Stache protocol uses Tempest's finegrain access control mechanisms to manage part of a processor's local memory as a large, fully-associative cache for remote data.  ...  Unlike the extensive, custom hardware in a COMA machine, Stache runs in userlevel software using the Tempest interface.  ... 
doi:10.1145/285930.286008 dblp:conf/isca/ReinhardtLW98a fatcat:2ggsngclordifld3ksmlfcri3m
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