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"El Sexo no es Malo": Maternal Values Accompanying Contraceptive Use Advice to Young Latina Adolescent Daughters

Laura F. Romo, Magali Bravo, Maria Elena Cruz, Rebeca M. Rios, Claudia Kouyoumdjian
2010 Sexuality Research & Social Policy  
. & ID 113 [M:31; D:12 years]: M: "Pero el sexo, el sexo no es malo. Esa es tu pregunta, que si es malo? No es malo." (M: "But sex, sex is not bad. Is that your question, if it is bad?  ... 
doi:10.1007/s13178-009-0001-6 pmid:20543876 pmcid:PMC2881211 fatcat:iiqsgwy7dvc4ngbemct6jzxpye

De indultos y malos tratos: dos causas de G. M. de Jovellanos en la Sala de Alcaldes de Casa y Corte (Madrid, 1779-1780)

Elena de Lorenzo Álvarez
2021 Historia Constitucional  
Sobre las actitudes de Jovellanos ante sus obras académicas y literarias, véase Elena de Lorenzo Álvarez, "G.  ...  Por un lado, Alloza constata que el 55% de los 1.095 hombres juzgados entre 1700 y 1766 lo fueron por maltratar a mujeres; y que en el 90% de los casos se trataba de malos tratos continuados en que las  ... 
doi:10.17811/hc.v0i22.765 fatcat:bxnug5qyhvcmxoadelews4nyne

Clasificación de rutas turísticas por medio de deep learning

Héctor Fernando Gómez Alvarado, María José Mayorga Ases, Leticia Abigail Mayorga Ases, Silvia Elena Malo Martínez
2022 ConcienciaDigital  
Introducción. Actualmente el deep learning o aprendizaje profundo tiene aplicaciones de todo tipo, el turismo no es la excepción, la minería de datos ha permitido optimizar procesos dentro de la industria del turismo como la demanda turística, conocer la preferencia de rutas turísticas de las personas permite optimizar recursos y plantear mejoras dentro de este sector. Objetivo. Determinar si se pueden clasificar rutas turísticas por medio de herramientas del deep learning o aprendizaje
more » ... . Metodología. El diseño de investigación fue cualitativo, se empleó técnicas como la entrevista, para ello se plantean dos hipótesis, la primera tiene que ver con la relación entre el tipo de clima del destino turístico y la preferencia de los turistas, la segunda hipótesis es la verificación de la conformación de clusters turísticos en base a la preferencia de las personas. Como herramientas de verificación se empleó la comprobación directa y el programa Weka con la opción de clusters SimpleKMeans que permite la identificación de las preferencias de los turistas en base a la minería de datos de 31 personas. Resultados. Los resultados indican que la mayor cantidad de personas entrevistadas prefieren destinos turísticos en climas calurosos, sin embargo, este no fue un parámetro determinante en la conformación de clusters. Conclusión. En el estudio se determinó que sí se puede formar clusters de clasificación de rutas turísticas en base a las preferencias de las personas.
doi:10.33262/concienciadigital.v5i1.1.2038 fatcat:jzqsdqmalfg5xm4gwmno55mbwa

Consumo de fármacos utilizados en el tratamiento del dolor musculoesquético en una cohorte de trabajadores manuales de Zaragoza

Elena Maria Gaspar Calvo, M� Jesús Lallana Álvarez, Sara Malo Fumanal
2020 Revista de la Sociedad Española del Dolor  
Correspondencia: Elena Gaspar Calvo egaspar@salud.aragon.es Gaspar Calvo E, Lallana Álvarez MJ, Malo S.  ... 
doi:10.20986/resed.2020.3749/2019 fatcat:6sroxy5uibdita6nvfm6nesywe

Sensory function in cluster headache: an observational study comparing the symptomatic and asymptomatic sides

Miguel Malo-Urriés, César Hidalgo-García, Elena Estébanez-de-Miguel, José Miguel Tricás-Moreno, Sonia Santos-Lasaosa, Marjan Jahanshahi
2018 Neuropsychiatric Disease and Treatment  
peripheral nerve fibers that innervate the pain-producing cranial vessels and dura mater and the centrally projecting fibers that synapse in the trigeminocervical complex. 9 correspondence: Miguel Malo-Urriés  ... 
doi:10.2147/ndt.s186051 pmid:30573960 pmcid:PMC6292232 fatcat:6cychlvyrfastkhhdjokatpday

Chronic kidney disease and acute kidney injury in the COVID-19 Spanish outbreak

Jose Portolés, María Marques, Paula López-Sánchez, María de Valdenebro, Elena Muñez, María Luisa Serrano, Rosa Malo, Estefanya García, Valentín Cuervas
2020 Nephrology, Dialysis and Transplantation  
Background Novel coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread, affecting >10 million cases worldwide. Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and primarily manifesting as an acute respiratory failure with interstitial and alveolar pneumonia, it can also affect multiple organs. Kidney involvement was underestimated in early reports and its role remains controversial. The aim of this study was to analyse the role of kidney damage in
more » ... D-19 outcome. Methods This is a prospective cohort study of 1603 consecutive patients admitted in a University Reference Hospital in the heart of the European outbreak. Results Median age was 64 years, 40.4% were female, 15.2% presented diabetes mellitus, 35.7% hypertension and 20.3% obesity. On admission, the prevalence of elevated serum creatinine (sCr), proteinuria, leucocyturia and haematuria were 21.0, 37.8, 31.8 and 45.6%, respectively. In total, 43.5% of those with an elevated sCr had previous chronic kidney disease (CKD) and 11.4% of those with normal sCr developed an in-hospital acute kidney injury (AKI); 17 patients needed acute haemodialysis; and 197 patients died during hospitalization. Cox proportional hazard regression confirmed that elevated baseline sCr [hazard ratio (95% confidence interval) 2.40 (1.79–3.22)], previous CKD [1.59 (1.06-2.37)], haematuria [1 + 1.68 (0.92–3.06), 2–3 + 2.69 (1.49–4.87)] and in-hospital AKI [1.50 (0.92–2.44)] were independent risk factors for in-hospital death after adjusting for age, sex and comorbidity. Conclusion The prevalence of acute and chronic kidney disease on admission and in-hospital AKI is higher than previously reported in Wuhan, and is associated with high in-hospital mortality. We should increase our awareness towards kidney involvement and design specific strategies for management of COVID-19 in these patients.
doi:10.1093/ndt/gfaa189 pmid:32871592 fatcat:bzzncwkhy5ebri7cxj2ydwbzey

Persistencia con estatinas en prevención primaria de enfermedad cardiovascular: resultados en una cohorte de trabajadores españoles

Sara Malo, Isabel Aguilar-Palacio, Cristina Feja, Enrica Menditto, María Jesús Lallana, Elena Andrade, José Antonio Casasnovas, María José Rabanaque
2018 Revista Española de Cardiología  
G Model RECESP-3334; No. of Pages 7 Có mo citar este artículo: Malo S, et al.  ...  Rev Esp Cardiol. 2017. http://dx.doi.org/10.1016/j.recesp.2017.03.027 Có mo citar este artículo: Malo S, et al.  ... 
doi:10.1016/j.recesp.2017.03.027 fatcat:7jnyd5x7srgs3p2xaznkv5oo2y

Persistence With Statins in Primary Prevention of Cardiovascular Disease: Findings From a Cohort of Spanish Workers

Sara Malo, Isabel Aguilar-Palacio, Cristina Feja, Enrica Menditto, María Jesús Lallana, Elena Andrade, José Antonio Casasnovas, María José Rabanaque
2018 Revista española de cardiología (English ed.)  
Introduction and objectives: The aim of this study was to assess patterns of treatment persistence in a cohort of male Spanish workers receiving statin therapy for primary prevention of cardiovascular disease. Methods: This descriptive study was conducted within the framework of the prospective longitudinal Aragon Workers' Health Study (N = 5400). Incident male statin users were identified based on data collected from the regional government's medication consumption information system. Patterns
more » ... of treatment persistence with statins prescribed for primary cardiovascular disease prevention were assessed and the relevance of potential predictors explored. Results: Among the 725 new statin users, less than one third remained persistent during the 1 year of follow-up. About 15% of nonpersistent users discontinued statin therapy after dispensation of the first prescription; of these, 42.1% did not recommence treatment within the following year. Factors reducing the likelihood of treatment discontinuation were older age (HR, 0.55; 95%CI, 0.39-0.77) and cotreatment with antihypertensive drugs (HR, 0.68; 95%CI, 0.56-0.82). No association was observed between treatment persistence and cotreatment with antidiabetic or antithrombotic drugs, baseline low-density lipoprotein levels, or total cholesterol levels. However, persistence was influenced by the type of statin first prescribed. Conclusions: Our analysis of a cohort of healthy male workers revealed poor statin persistence. These findings underscore the need for a better understanding of patterns of statin use, especially in apparently healthy individuals, and for the incorporation of patient behavior into prescribing decisions. C 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved. Persistencia con estatinas en prevenció n primaria de enfermedad cardiovascular: resultados en una cohorte de trabajadores españ oles Palabras clave: Interrupció n Fá rmaco hipolipemiante Farmacoepidemiología Medicació n Medició n Enfermedad cardiovascular Prevenció n primaria R E S U M E N Introducción y objetivos: El objetivo de este estudio es analizar el patró n de persistencia con estatinas en prevenció n primaria de enfermedad cardiovascular en una cohorte de trabajadores españ oles. Me´todos: Este estudio descriptivo se llevó a cabo en el marco del estudio prospectivo longitudinal Aragon Workers' Health Study (n = 5.400). Se identificó a los nuevos usuarios de estatinas varones a partir de datos recogidos en el sistema de informació n de consumo farmacé utico de Aragó n. Se analizaron los patrones de persistencia con estatinas prescritas en prevenció n primaria cardiovascular, así como los potenciales predictores. Resultados: De los 725 nuevos usuarios de estatinas, menos de un tercio habían persistido durante el añ o de seguimiento. Alrededor de un 15% de los usuarios no persistentes interrumpieron la terapia con estatinas tras la dispensació n de la primera receta y, el 42,1% de ellos no reiniciaron el tratamiento durante el resto del añ o. La mayor edad (HR = 0,55; IC95%, 0,39-0,77) y el cotratamiento con fá rmacos antihipertensivos (HR = 0,68; IC95%, 0,56-0,82) redujeron la probabilidad de que se interrumpiera el tratamiento. No se observó asociació n entre la persistencia con el tratamiento y la toma concomitante de fá rmacos antidiabé ticos o antitrombó ticos, las concentraciones basales de lipoproteínas de baja densidad o las de colesterol total. Sin embargo, la persistencia sí estuvo influida por el tipo de la primera estatina prescrita.
doi:10.1016/j.rec.2017.04.002 pmid:28473266 fatcat:fjbclxsm5rdv7jj4c7op25truq

The Potential Applications of Bacillus sp. and Pseudomonas sp. Strains with Antimicrobial Activity against Phytopathogens, in Waste Oils and the Bioremediation of Hydrocarbons

Mariana-Gratiela Soare (Vladu), Elena Simina Lakatos, Nicoleta Ene, Nereida Malo (Dalanaj), Ovidiu Popa, Narcisa Babeanu
2019 Catalysts  
Biodegradation is one of the primary mechanisms for the elimination of petroleum and other hydrocarbon pollutants from the environment. This study presents the results obtained with two newly isolated microorganisms and their potential applications in bioremediation, agriculture, and industrial fields. Twenty-five strains of microorganisms were isolated from plant materials and were subject to a selection process on the basis of antimicrobial activity. Two bacterial strains, respectively
more » ... s mycoides (Bm) and Pseudomonas putida (B1), were selected for further experiments, based on the largest inhibition zones against the phytopathogens Erwinia carotovora and Xanthomonas campestris. The production of biosurfactants and enzymes was evaluated in specific media. In order to assess the production of biosurfactants, submerged bioprocesses were carried out on Yeast Malt Peptone Glucose (YMPG), M44, Luria-Bertani (LB), and King B media (KB); the supernatants were used to form emulsions with heptane, octane, and sunflower oil, and the emulsifying indices were determined.
doi:10.3390/catal9110959 fatcat:zgbua6gtcvh7nkv47rrgf6ufqu

Evaluation of Convalescent Plasma versus Standard of Care for the Treatment of COVID-19 in Hospitalazed Patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial [article]

Elena Diago-Sempere, Jose Luis Bueno, Aranzazu Sancho-Lopez, Elena Munez-Rubio, Ferran Torres, Rosa Malo de Molina, Ana Fernandez-Cruz, Isabel Salcedo De Diego, Ana Velasco-Iglesias, Concepcion Payares Herrera, Inmaculada Casas Flecha, Cristina Avendano-Sola (+3 others)
2020 medRxiv   pre-print
Rosa Malo de Molina, Servicio de Pneumology. Hospital Universitario Puerta de Hierro Majadahonda -Dr. Ferrán Torres, Clinical Pharmacology Department. Hospital Clínic Barcelona.  ...  Elena Múñez, Internal Medicine Department. Infectious diseases unit. Hospital Universitario Puerta de Hierro Majadahonda -Dr. Belén Ruiz-Antorán, Clinical Pharmacology Department.  ... 
doi:10.1101/2020.07.31.20165720 fatcat:r6nswh5nknhafezt65xt2fhrle

Behavioral Types in Programming Languages

Davide Ancona, Viviana Bono, Mario Bravetti, Joana Campos, Giuseppe Castagna, Pierre-Malo Deniélou, Simon J. Gay, Nils Gesbert, Elena Giachino, Raymond Hu, Einar Broch Johnsen, Francisco Martins (+7 others)
2016 Foundations and Trends® in Programming Languages  
Mario Bravetti, Elena Giachino and Einar Broch Johnsen have been supported by the EU project FP7-610582 Envisage: Engineering Virtualized Services (http://www.envisage-project.eu).  ... 
doi:10.1561/2500000031 fatcat:p3a4ohzlvvfjhiathi7oztvyzi

Response of Aspergillus niger Inoculated on Tomatoes Exposed to Vapor Phase Mustard Essential Oil for Short or Long Periods and Sensory Evaluation of Treated Tomatoes

Ana Elena Aguilar-González, Enrique Palou, Aurelio López-Malo
2017 Journal of Food Quality  
The inhibitory effect of mustard essential oil (EO) in vapor phase against Aspergillus niger was evaluated in vitro and in vivo (in tomatoes). Mold response in tomatoes exposed for short or long periods to selected concentrations of mustard EO was also evaluated. Furthermore, a sensory evaluation was also performed among treated tomatoes and compared with nontreated ones. Minimum inhibitory concentration (MIC) for the studied EO was determined by the inverted Petri dish method. MIC for the in
more » ... tro and in vivo tests for mustard EO was of 3.08 μL/Lair. In vitro and in vivo results demonstrate the effectiveness of vapors of mustard EO against A. niger. The studied EO contains highly volatile organic compounds with strong inhibitory effects, even when applied for short periods, and can consequently be considered a good alternative to traditional synthetic antimicrobials without detriment of selected sensory attributes.
doi:10.1155/2017/4067856 fatcat:6p5whdrlk5d7de5pyrx4jx37qe

Evaluation of convalescent plasma versus standard of care for the treatment of COVID-19 in hospitalized patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial

Elena Diago-Sempere, José Luis Bueno, Aránzazu Sancho-López, Elena Múñez Rubio, Ferrán Torres, Rosa Malo de Molina, Ana Fernández-Cruz, Isabel Salcedo de Diego, Ana Velasco-Iglesias, Concepción Payares-Herrera, Inmaculada Casas Flecha, Cristina Avendaño-Solà (+3 others)
2021 Trials  
Rosa Malo de Molina, Servicio de Pneumology. Hospital Universitario Puerta de Hierro Majadahonda Dr. Ferrán Torres, Clinical Pharmacology Department. Hospital Clínic Barcelona.  ...  Elena Múñez, Internal Medicine Department. Infectious diseases unit. Hospital Universitario Puerta de Hierro Majadahonda Dr. Belén Ruiz-Antorán, Clinical Pharmacology De- partment.  ... 
doi:10.1186/s13063-020-05011-9 pmid:33472681 fatcat:bvejwi5oinh47cfo7z4zeugl3y

Immediate Effects of Upper Cervical Translatoric Mobilization on Cervical Mobility and Pressure Pain Threshold in Patients With Cervicogenic Headache: A Randomized Controlled Trial

Miguel Malo-Urriés, José Miguel Tricás-Moreno, Elena Estébanez-de-Miguel, César Hidalgo-García, Andoni Carrasco-Uribarren, Sara Cabanillas-Barea
2017 Journal of Manipulative and Physiological Therapeutics  
Objective: The purpose of this study was to evaluate the immediate effects of upper cervical translatoric spinal mobilization (UC-TSM) on cervical mobility and pressure pain threshold in subjects with cervicogenic headache (CEH). Methods: Eighty-two volunteers (41.54 ± 15.29 years; 20 males and 62 females) with CEH participated in the study and were randomly divided into control or treatment group. Treatment group received UC-TSM and the control group remained in the same position and time than
more » ... UC-TSM group but received no treatment. Cervical mobility (active cervical mobility and flexion-rotation test (FRT)), pressure pain thresholds (PPT) over upper trapezius muscles, C2-C3 zygapophyseal joints and suboccipital muscles and current headache intensity (VAS) were measured before and immediately after the intervention by two blinded investigators. Results: After the intervention, UC-TSM group presented significant increases in total cervical mobility (p=0.002; d=0.16) and FRT (p<0.001;. No significant differences were observed between groups for cervical PPTs (p>0.05). Nevertheless, UC-TSM group showed a significantly lower intensity of headache (p=0.039; d=0.57). Conclusions: UC-TSM intervention increased upper and showed a tendency to improve general cervical range of motion and induce immediate headache relief in subjects with CEH. To confirm these results, further research considering the limitations of the present clinical trial is required. Number: NCT02422862 (clinicaltrials.gov) Clinical Trial Registration
doi:10.1016/j.jmpt.2017.07.007 pmid:29229055 fatcat:z7kdxucm75ad5omgiv7zwyrr3y

Impaired Cytotoxic Response in PBMCs From Patients With COVID-19 Admitted to the ICU: Biomarkers to Predict Disease Severity

Lorena Vigón, Daniel Fuertes, Javier García-Pérez, Montserrat Torres, Sara Rodríguez-Mora, Elena Mateos, Magdalena Corona, Adolfo J. Saez-Marín, Rosa Malo, Cristina Navarro, María Aranzazu Murciano-Antón, Miguel Cervero (+5 others)
2021 Frontiers in Immunology  
Infection by novel coronavirus SARS-CoV-2 causes different presentations of COVID-19 and some patients may progress to a critical, fatal form of the disease that requires their admission to ICU and invasive mechanical ventilation. In order to predict in advance which patients could be more susceptible to develop a critical form of COVID-19, it is essential to define the most adequate biomarkers. In this study, we analyzed several parameters related to the cellular immune response in blood
more » ... s from 109 patients with different presentations of COVID-19 who were recruited in Hospitals and Primary Healthcare Centers in Madrid, Spain, during the first pandemic peak between April and June 2020. Hospitalized patients with the most severe forms of COVID-19 showed a potent inflammatory response that was not translated into an efficient immune response. Despite the high levels of effector cytotoxic cell populations such as NK, NKT and CD8+ T cells, they displayed immune exhaustion markers and poor cytotoxic functionality against target cells infected with pseudotyped SARS-CoV-2 or cells lacking MHC class I molecules. Moreover, patients with critical COVID-19 showed low levels of the highly cytotoxic TCRγδ+ CD8+ T cell subpopulation. Conversely, CD4 count was greatly reduced in association to high levels of Tregs, low plasma IL-2 and impaired Th1 differentiation. The relative importance of these immunological parameters to predict COVID-19 severity was analyzed by Random Forest algorithm and we concluded that the most important features were related to an efficient cytotoxic response. Therefore, efforts to fight against SARS-CoV-2 infection should be focused not only to decrease the disproportionate inflammatory response, but also to elicit an efficient cytotoxic response against the infected cells and to reduce viral replication.
doi:10.3389/fimmu.2021.665329 pmid:34122423 pmcid:PMC8187764 fatcat:ks7522gq6zh7zkecn5ui5kgngq
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