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MTHFR promotes heterochromatin maintenance
2014
Biochemical and Biophysical Research Communications - BBRC
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to methionine. ...
Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in the folate cycle, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation ...
This work was supported by the National Natural Science ...
doi:10.1016/j.bbrc.2014.04.082
pmid:24769206
fatcat:u2xpebz72rah3gs3ic36mhn53i
Genome-Wide Association Study of Diabetogenic Adipose Morphology in the GENetics of Adipocyte Lipolysis (GENiAL) Cohort
2020
Cells
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We performed a genome-wide association study (GWAS) in the unique GENetics of Adipocyte Lipolysis (GENiAL) cohort comprising 948 participants who have undergone abdominal subcutaneous adipose biopsy with ...
We set out to identify genetic loci associated with adipose morphology and functionally evaluate candidate genes for impact on adipocyte development. ...
Tag genome-wide association study (GWAS) SNPs associated with type 2 diabetes and with adipose morphology in the current study. ...
doi:10.3390/cells9051085
pmid:32349335
pmcid:PMC7291295
fatcat:lmitb7cltff5hb4orgkmwmrddi
Advances in genetics and molecular breeding of three legume crops of semi-arid tropics using next-generation sequencing and high-throughput genotyping technologies
2012
Journal of Biosciences
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Molecular markers are the most powerful genomic tools to increase the efficiency and precision of breeding practices for crop improvement. ...
These trait-associated robust markers along with other genomic resources including genetic maps and genomic resources will certainly accelerate crop improvement programmes in the SAT legumes. ...
To overcome the constraints related to production in SAT legumes using genomics-assisted breeding, identification/ discovery of marker trait association between the trait of interest and a genetic marker ...
doi:10.1007/s12038-012-9228-0
pmid:23107917
fatcat:ef5z4ral4relfcbbmmpfjeyw5u
Identification of genes associated with productivity traits and salinity tolerance from activation tagged lines of rice
[article]
2021
bioRxiv
pre-print
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World-wide crop productivity is hugely impacted by diverse eco-environmental conditions. ...
Furthermore, AT lines disclosed enhanced plant water content, photosynthetic efficiency, stomatal conductance, water use efficiency and maximum quantum yield when compared to WT plants, leading to improved ...
These results indicate that AT lines showed higher A Sat values by 25% to 50 % under 3 5 4 . ...
doi:10.1101/2021.01.22.427785
fatcat:7cl736tglzcahiyiopnuskfe6e
Rex (Encoded by DVU_0916) in Desulfovibrio vulgaris Hildenborough Is a Repressor of Sulfate Adenylyl Transferase and Is Regulated by NADH
2014
Journal of Bacteriology
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Although the enzymes for dissimilatory sulfate reduction by microbes have been studied, the mechanisms for transcriptional regulation of the encoding genes remain unknown. ...
Therefore, the DVU_0916 protein has been predicted to be a transcriptional repressor of genes encoding proteins that function in the process of sulfate reduction inD. vulgarisHildenborough. ...
From an examination of genome sequences, Rex has been predicted to be present in a wide range of microbes, including Gram-negative and Grampositive aerobes and anaerobes. ...
doi:10.1128/jb.02083-14
pmid:25313388
pmcid:PMC4288696
fatcat:kfdh3byjufhn7je2xipzpgmnfi
Photosynthetic parameters of switchgrass (Panicum virgatum) under low radiation: Influence of stable overexpression of Miscanthus×giganteus PPDK on responses to light and CO2 under warm and cool growing conditions
2015
New Negatives in Plant Science
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Abbreviations: A/C i curve, photosynthetic response to intercellular CO 2 concentration; A/Q curve, photosynthetic response to incident light curve; A sat , light saturated photosynthetic rate; AQE, apparent ...
Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). ...
The authors would like to thank John Goodwin for technical assistance. ...
doi:10.1016/j.neps.2015.08.001
fatcat:sl5slynkyngphmfd4j3eplwvs4
Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania
2019
PLoS Genetics
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wide patterns of recombination, demonstrating that classical crossing over occurs at meiosis, and allowed us to construct the first physical and genetic maps in Leishmania. ...
The hybrids were equivalent to F1 progeny, heterozygous throughout most of the genome for the markers that were homozygous and different between the parents. ...
The extra genome was contributed by LiL/HYG to three of the hybrids, and by LmFV1/SAT to one. ...
doi:10.1371/journal.pgen.1008042
pmid:31091230
pmcid:PMC6519804
fatcat:25k3raitnnfrneapif5jkb5p3m
Genome-Wide Association Study ofArabidopsis thalianaIdentifies Determinants of Natural Variation in Seed Oil Composition
2015
Journal of Heredity
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The renewable source of highly reduced carbon provided by plant triacylglycerols (TAGs) fills an ever increasing demand for food, biodiesel, and industrial chemicals. ...
Here, we characterized the seed oil composition of 391 world-wide, wild accessions of Arabidopsis thaliana, and performed a genome-wide association study (GWAS) of the 9 major fatty acids in the seed oil ...
Acknowledgments Thank you to T. Juenger for providing accession seed. We are grateful for analysis advice from G. Morrison, J. Lasky and T. Nakov. ...
doi:10.1093/jhered/esv100
pmid:26704140
pmcid:PMC4885229
fatcat:4o5brijitja6vhwnuwlkit7pvm
Validity of a new automated software program for visceral adipose tissue estimation
2006
International Journal of Obesity
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Objective: Our aim was to compare estimates of VAT (visceral adipose tissue) and SAT (subcutaneous adipose tissue) using the new Hippo Fatt software against those from a widely used, validated, computer-assisted ...
Average VAT was 9.4% lower and average SAT was 3.7% higher using Hippo Fatt compared to slice-O-matic; the overestimation of SAT tended to be greater among individuals with greater adiposity. ...
Acknowledgements This work was supported by Grants HD12252 and DK064870 from the National Institutes of Health, Bethesda, MA, USA. ...
doi:10.1038/sj.ijo.0803409
pmid:16770332
pmcid:PMC1783906
fatcat:tytynfj4erhfrg4fgniq6ubynm
From sulfur to homoglutathione: thiol metabolism in soybean
2010
Amino Acids
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Here, we review the details of thiol metabolism in soybean, its potential biotechnology value, what is known about the pathways from sulfur uptake to glutathione synthesis in soybean, how the soybean genome ...
from the soybean genome may guide the next steps in exploring this biochemical system. ...
C-terminal phosphorylation of SAT affects CRC formation and whether this post-translation modification is more widely used to modulate feedback inhibition by cysteine. ...
doi:10.1007/s00726-010-0572-9
pmid:20364282
fatcat:bbcvxuhda5g63ld5dssumg2vsy
Affinity Purification of O-Acetylserine(thiol)lyase from Chlorella sorokiniana by Recombinant Proteins from Arabidopsis thaliana
2014
Metabolites
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In order to enable the identification of OASTL proteins from non-model organisms such as C. sorokiniana, the recombinant his-tagged SAT5 protein from Arabidopsis thaliana was immobilized by metal chelate ...
The successful application of SAT/OASTL interaction for purification confirms for the first time the existence of the cysteine synthase complexes in microalgae. ...
Acknowledgments Giovanna Salbitani was supported by a fellowship (FORGIARE) funded by Polo delle Scienze e delle Tecnologie, University "Federico II" of Naples and by Compagnia San Paolo di Torino. ...
doi:10.3390/metabo4030629
pmid:25093930
pmcid:PMC4192684
fatcat:q427raee3ffrhavpght357zxuu
The Tag Genome
2012
ACM transactions on interactive intelligent systems (TiiS)
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We describe an application of the tag genome called Movie Tuner which enables users to navigate from one item to nearby items along dimensions represented by tags. ...
This article introduces the tag genome, a data structure that extends the traditional tagging model to provide enhanced forms of user interaction. ...
Like Symeonidis et al. [2008] , we apply dimensionality reduction techniques to overcome the sparsity in tagging systems. ...
doi:10.1145/2362394.2362395
fatcat:hnlpdmuofzfn7ak2znus4awuga
Niche partitioning in the Rimicaris exoculata holobiont: the case of the first symbiotic Zetaproteobacteria
2021
Microbiome
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Results Our data enabled us to reconstruct 49 metagenome-assembled genomes (MAGs) from the TAG and Rainbow vent fields, including 16 with more than 90% completion and less than 5% contamination based on ...
Here, we generated shotgun metagenomes from Rimicaris exoculata cephalothoracic epibiotic communities to reconstruct and investigate symbiotic genomes. ...
We are really grateful to two anonymous reviewers for their constructive comments, which helped us to improve the manuscript. ...
doi:10.1186/s40168-021-01045-6
pmid:33845886
pmcid:PMC8042907
fatcat:mkkfjnxlefas3cjvi2nd2vad3i
Insect phylogenomics: results, problems and the impact of matrix composition
2012
Proceedings of the Royal Society of London. Biological Sciences
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.), and Paraneoptera (thrips, lice, bugs in the wide sense). ...
As recent EST datasets are characterized by a heterogeneous distribution of available genes across taxa, we use different rationales to optimize the data matrix composition. ...
B.M. and K.M. were supported by the DFG grant MI 649/6. ...
doi:10.1098/rspb.2012.0744
pmid:22628473
pmcid:PMC3385742
fatcat:pjibn2lembdchnwvybcmzoswqa
A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS)
2015
PLoS ONE
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Five SNPs from two novel loci attained genome-wide significance (P<5.00x10 -8 ) in IRASFS. ...
In conclusion, a genome-wide and exome chip association study was conducted that identified two novel loci (IDH1 and ZGRF1) associated with adiposity. ...
The authors would like to acknowledge the members of the GUARDIAN Consortium. ...
doi:10.1371/journal.pone.0134649
pmid:26599207
pmcid:PMC4658008
fatcat:ntprrulvkja7lcfih62542ahim
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