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Efficient Capture and Raman Analysis of Circulating Tumor Cells by Nano-Undulated AgNPs-rGO Composite SERS Substrates

Jong-Eun Park, Nuri Oh, Hyeono Nam, Ji-Ho Park, Sanha Kim, Jessie S. Jeon, Minyang Yang
2020 Sensors  
In this study, we present a novel surface-enhanced Raman scattering (SERS) substrate for the efficient capture and characterization of cancer cells using silver nanoparticles-reduced graphene oxide (AgNPs-rGO  ...  As a result, MCF7 breast cancer cells are efficiently captured on the AgNPs-rGO substrates, about four times higher than the AgNWs-GO films, and the captured living cells are successfully analyzed by SERS  ...  (a) The electric field-assisted pulsed laser reduction for the fabrication of the nano-undulated AgNPs-rGO composite substrate; (b) Capture and surface-enhanced Raman scattering (SERS) analysis of circulating  ... 
doi:10.3390/s20185089 pmid:32906807 fatcat:htuwk3hrtrbyhdzd3z63pg27ea