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Opioid overdose counseling and prescribing of naloxone in rural community pharmacies: A pilot study

Benjamin S. Teeter, Mary M. Thannisch, Bradley C. Martin, Nickolas D. Zaller, Duane Jones, Cynthia L. Mosley, Geoffrey M. Curran
<span title="2021-05-08">2021</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/prvxs7ggfzagbopgbsbizztz6u" style="color: black;">Exploratory Research in Clinical and Social Pharmacy</a> </i> &nbsp;
The objective of this study was to pilot test a proactive opioid overdose counseling intervention and a passive naloxone intervention, and the implementation strategies developed to support their delivery  ...  Between the 2 intervention pharmacies, 130 patients received the opioid overdose counseling intervention. 44 (33.8%) were prescribed and dispensed naloxone.  ...  A number of states have mandated naloxone be coprescribed for patients on high-risk opioids and patients prescribed concomitant opioids and benzodiazepines.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.rcsop.2021.100019">doi:10.1016/j.rcsop.2021.100019</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/35128518">pmid:35128518</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8813166/">pmcid:PMC8813166</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/vpgrmmt6jnca7maqoo5cleg2ve">fatcat:vpgrmmt6jnca7maqoo5cleg2ve</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210527080851/https://pdf.sciencedirectassets.com/779205/1-s2.0-S2667276621X00030/1-s2.0-S2667276621000196/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEJf%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIQDG5CzmBYuiTp0XdLFzZM%2FBN3kvLa%2BXiIEVMBDgsZlZNgIgToYUSIzpYYmQFNZPCrfMRgH%2BYqUPGzjBWi9FVRrGd%2FMqtAMIQBADGgwwNTkwMDM1NDY4NjUiDFoMuMLEq1NKwhWRASqRA2FXTinCwHwocU4eyXsmBQw6KPT2SwWdxYbJCI%2BnMY5WFfATpqW0rEXpFfsfMFds5ndF0jHRNX3zsIYqktrlP3R6W%2B5xDjN%2FVrT82JoVLXnFmhhiD4A%2FrYXWfh%2FqioGkdcMUCqa9mzu%2F1nQEEQbu9mKiogHSAVd5F2PGYx%2BYUK0uc1BseBVQ6s%2F%2FMzSEg7eANlEBAqVhA8ln7tN4uBMOK29mpXSdSXROpkPcKXIMSay47AnU52iNlFRaP%2FdGtrswvDtxbMPbT2lFy%2Fw3nWnsJDSfrq8%2FgBCtL2n9cP%2Fq99CTkiQqFR7qox64uOXEvvhAGGH8hqT44cxdw2fRYIUz30fthropIoD0y8UZjCoNH0V%2FmeaMeDWBYU41l7L8C%2BQt8EK2cqFboM%2BWLIzxE%2B3W0GFyopVOPMEkx6jyIoIO1r%2BCiCMXJTUmqMsCWXpOpHUs2iiJ%2B2jaNatQyvW7g9dGng%2FiTONv4mOpQfPCW2RfXcRrS3ouje%2B4zMNg4eTotOxWt02wa0LCyipgznfFpmtbbqBTMPGAvYUGOusBSQIjm6a%2FTWu5Rc3%2FomGkmLN6TToa5R3Kq2ZCEQpIbnzEwN0KcWwn%2BmECVp4Ff7oAfqBf4SQ1NqDr%2B7FDqQASlUr3WSOsH9HmKKjitipPfomEBfzsOBw12hUUt3yvEW2YTScyMETjH10YtdbVsxgSq%2BWI6vM%2BafO2nPP2h7uwRN10psEbgZwgzLCkpGY6cAybWiFtPOod%2FGCgu1B3JBm22ZV5vR2ZYLa%2F5T45b%2FdtCxIYDVbHLYSzFSeIjOmpAI%2Frq%2BCRGUxJmhi9NMaM23TuoFKwrJLItIcctrk8mdbPqH93PWIK6tgNYd8zgQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20210527T080847Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYUO4DJV5H%2F20210527%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=74059098f1d6ed8bf597620136324661c2e77671acc5a19498ab1d00f2cf1a31&amp;hash=cfed027a8a754b48e4d9a0687b2a1fd4e63296c1578f6dd96885be9f4549d5db&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2667276621000196&amp;tid=spdf-083045dd-117a-4ffc-b0e6-ffbdebf73385&amp;sid=82fcf8d92730724e309aa03-4eb4c3e2df2dgxrqa&amp;type=client" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/54/21/5421c7556c6c9552ec3dc1fea0b667ea8fcaeb6d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.rcsop.2021.100019"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813166" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The Benefits and Potential Drawbacks in the Approval of EVZIO for Lay Reversal of Opioid Overdose

Leo Beletsky
<span title="">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3udjmbs5yjcnjgfox7chccjfqy" style="color: black;">American Journal of Preventive Medicine</a> </i> &nbsp;
Views expressed are those of the author and do not necessarily reflect the views of the National Institutes on Drug Abuse or NIH.  ...  Acknowledgments Beletsky is supported in part by NIH, National Institutes on Drug Abuse grant No. R37DA019829 (S. Strathdee, principal investigator).  ...  crisis, endorsement of naloxone education and co-prescription with extended release and long-acting opioids is also evolving. 6 When intended for individuals at possible risk of overdose, naloxone can  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.amepre.2014.09.011">doi:10.1016/j.amepre.2014.09.011</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25547930">pmid:25547930</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4339419/">pmcid:PMC4339419</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/kalox274xvabpogeoqdstjpg5q">fatcat:kalox274xvabpogeoqdstjpg5q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200209043614/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4339419&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/3d/bf/3dbfae674e82a34d5de43cd57a6ad854ed3ec7c4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.amepre.2014.09.011"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339419" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

U.S. Opioid Epidemic: Impact on Public Health and Review of Prescription Drug Monitoring Programs (PDMPs)

Sunghee H Bote
<span title="2019-09-20">2019</span> <i title="University of Illinois Libraries"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/u4k6gfb6nncyfg3hvo3dvjo2ay" style="color: black;">Online Journal of Public Health Informatics</a> </i> &nbsp;
The PDMP integrated clinical decision support systems need to supply to healthcare providers access to complete, timely and evidence-based information that can meaningfully inform prescribing decisions  ...  In addition, PDMP integration and interoperability efforts are advancing to provide prescribers meaningful decision support tools.Discussion: The opioid epidemic has a complex impact on public health intertwined  ...  For PDMPs to be meaningful clinical decision support tool for prescribing decisions and data source for public health departments to inform targeted interventions, complete and consistent real time data  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5210/ojphi.v11i2.10113">doi:10.5210/ojphi.v11i2.10113</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31632612">pmid:31632612</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6788897/">pmcid:PMC6788897</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6jygd6gpqbhstebok7om5zoa7u">fatcat:6jygd6gpqbhstebok7om5zoa7u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200212233141/https://journals.uic.edu/ojs/index.php/ojphi/article/download/10113/8097" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/28/50/285003f2d881ed525ba3b699d2b7370b73b632b9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5210/ojphi.v11i2.10113"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788897" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Prescription reporting with immediate medication utilization mapping (PRIMUM): development of an alert to improve narcotic prescribing

Rachel B. Seymour, Daniel Leas, Meghan K. Wally, Joseph R. Hsu
<span title="2016-08-22">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/bnylrk2y7bfnrn7u2f2vjkx7ta" style="color: black;">BMC Medical Informatics and Decision Making</a> </i> &nbsp;
The alert would have fired in 21.75 % of prescribing encounters (1.30 % of all encounters; n = 9998), suggesting the alert will have a low prescriber burden yet capture a significant number of at-risk  ...  Methods: A multidisciplinary Expert Panel identified risk factors for misuse, abuse, or diversion of opioids or benzodiazepines through literature reviews and consensus building for inclusion in a rule  ...  We determined this rate was low, and we had the potential to identify a greater number of at risk patients without burdening prescribers with high alert rates.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12911-016-0352-x">doi:10.1186/s12911-016-0352-x</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27549364">pmid:27549364</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4994311/">pmcid:PMC4994311</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dcy2bucvofh75mhyo3rkcco6d4">fatcat:dcy2bucvofh75mhyo3rkcco6d4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180720215847/https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-016-0352-x" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/af/0f/af0f0a26aec1e9616ad7e3d10b4840a6f0a1f207.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12911-016-0352-x"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994311" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Prescription opioid abuse: pharmacists' perspective and response

Gerald Cochran, Valerie Hruschak, Brooke DeFosse, Kenneth C. Hohmeier
<span title="">2016</span> <i title="Dove Medical Press Ltd."> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nsiq37smsjaqbiupcifzjc5bcy" style="color: black;">Integrated Pharmacy Research and Practice</a> </i> &nbsp;
In particular, evidence and arguments are presented for proactively identifying and intervening with patients who abuse and/or are at risk for overdose.  ...  This article provides a brief review of the antecedents, driving forces, and health status of patients involved in the opioid medication and overdose epidemic.  ...  Rapidly escalating overdose deaths has called national attention to the need for effective approaches to reach individuals at-risk of overdose from illicit heroin use and NMPO. 56 While overdose previously  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2147/iprp.s99539">doi:10.2147/iprp.s99539</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29354541">pmid:29354541</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5741039/">pmcid:PMC5741039</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lmxcv7inlbhqbialf7qngw3scq">fatcat:lmxcv7inlbhqbialf7qngw3scq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180724135616/https://www.dovepress.com/getfile.php?fileID=32081" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7a/f4/7af451f0aa3adfab1a43cc9afd59c01256cf0802.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2147/iprp.s99539"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741039" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

We must declare Scotland's drug deaths a public health emergency

<span title="">2019</span> <i title="Royal Pharmaceutical Society"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/v5jxgtakhzb2bkp4nlfumnregu" style="color: black;">Pharmaceutical journal (1933)</a> </i> &nbsp;
These include the Take Home Naloxone (THN) program that provides training and kits, including the opioid antagonist naloxone, to individuals at high risk of overdose.  ...  patient overdose information back to prescribing physicians to encourage better care  Publish results of street drug sample analysis and drug checking, including alerts on any dangerous circulating substances  ...  Action Exchange: BC Overdose Action Exchange The BC Overdose Action Exchange brings together representatives of approximately 30 organizations at the BC Centre for Disease Control (BCCDC) office in  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1211/pj.2019.20207047">doi:10.1211/pj.2019.20207047</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cryexntvbzhkvgmqcbwl5l2on4">fatcat:cryexntvbzhkvgmqcbwl5l2on4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170908231006/http://www.bccdc.ca/resource-gallery/Documents/BCOAE-Meeting-Report.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/63/e4/63e4436cafad2549c03dcd4380f953945af5cbe1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1211/pj.2019.20207047"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Can pharmaceutical companies contribute to the quality use of medicines?

Peter Mansfield
<span title="2010-08-01">2010</span> <i title="NPS MedicineWise"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sj4b4rih4ffmjhzkhwi2i4cqku" style="color: black;">Australian Prescriber</a> </i> &nbsp;
Regardless of whether opioid use is licit or illicit, anyone at risk of opioid overdose should be considered for naloxone.  ...  Any person at risk of an opioid overdose, or those likely to be present at an opioid overdose, should be considered for training.  ...  Conflict of interest: none declared Published by Independent, not-for-profit and evidence based, NPS MedicineWise enables better decisions about medicines and medical tests.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.18773/austprescr.2010.049">doi:10.18773/austprescr.2010.049</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/h3nncmiq5rduzjahwgn6zo2az4">fatcat:h3nncmiq5rduzjahwgn6zo2az4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180722032135/https://cdn1.scrvt.com/08ab3606b0b7a8ea53fd0b40b1c44f86/965258dc9ab072cd/97b050a505db/August-issue-40-4.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/49/54/495454dbfff561a206bd8227dcd9a58d3fafb46f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.18773/austprescr.2010.049"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Some Additional Considerations Regarding the American Society of Addiction Medicine National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use

Andrew J. Saxon, Elinore F. McCance-Katz
<span title="">2016</span> <i title="Ovid Technologies (Wolters Kluwer Health)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/c77upzoogfailmhslu6x2jg43e" style="color: black;">Journal of addiction medicine</a> </i> &nbsp;
Reentry into the community after imprisonment is a high-risk period for relapse to opioid misuse and overdose.  ...  SAMHSA supports the use of naloxone for the treatment of opioid overdose by bystanders in their Opioid Overdose Prevention Toolkit. 168 Routes of Administration Naloxone is marketed in vials for injection  ...  Areas for Further Research • Further research is needed on the effectiveness of pharmacotherapy in prisoner populations.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/adm.0000000000000219">doi:10.1097/adm.0000000000000219</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27223833">pmid:27223833</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/scy6kueo4vdtbk4epcwj66g2iq">fatcat:scy6kueo4vdtbk4epcwj66g2iq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190309205712/http://pdfs.semanticscholar.org/ffc1/9dae3ff748fed7eebb1f7989ca0192fcc989.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ff/c1/ffc19dae3ff748fed7eebb1f7989ca0192fcc989.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/adm.0000000000000219"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Take-Home Naloxone for the Emergency Interim Management of Opioid Overdose: The Public Health Application of an Emergency Medicine

John Strang, Rebecca McDonald, Gabrielle Campbell, Louisa Degenhardt, Suzanne Nielsen, Alison Ritter, Ola Dale
<span title="2019-07-27">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/locqtuz67feo7gdm3ssw33d5by" style="color: black;">Drugs</a> </i> &nbsp;
Naloxone is a well-established essential medicine for the treatment of life-threatening heroin/opioid overdose in emergency medicine.  ...  There is an urgent need for more widespread naloxone access considering the growing problem of opioid overdose deaths, accounting for more than 100,000 deaths worldwide annually.  ...  Clinical Effects Naloxone can reverse serious effects of opioids such as respiratory depression and stupor.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s40265-019-01154-5">doi:10.1007/s40265-019-01154-5</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31352603">pmid:31352603</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6728289/">pmcid:PMC6728289</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6jxyyyzlqzdkhiepz25debvtxm">fatcat:6jxyyyzlqzdkhiepz25debvtxm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200311125306/https://link.springer.com/content/pdf/10.1007%2Fs40265-019-01154-5.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/52/ab/52abfdf842a07047fc971b1b26aa3f8965677e75.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s40265-019-01154-5"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728289" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Opioid prescribing decreases after learning of a patient's fatal overdose

Jason N. Doctor, Andy Nguyen, Roneet Lev, Jonathan Lucas, Tara Knight, Henu Zhao, Michael Menchine
<span title="2018-08-09">2018</span> <i title="American Association for the Advancement of Science (AAAS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qirzh7firjdsjhg4tutxtir6ey" style="color: black;">Science</a> </i> &nbsp;
Most opioid prescription deaths occur among people with common conditions for which prescribing risks outweigh benefits.  ...  To test these hypotheses, we conducted a randomized trial of 861 clinicians prescribing to 170 persons who subsequently suffered fatal overdoses.  ...  Second, clinicians are also disproportionately exposed to patients who return to their clinics uneventfully for an opioid refill.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1126/science.aat4595">doi:10.1126/science.aat4595</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30093595">pmid:30093595</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/n6vgqnxju5aknp4dwdojwq4ca4">fatcat:n6vgqnxju5aknp4dwdojwq4ca4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200520151331/https://science.sciencemag.org/content/sci/361/6402/588.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c1/f2/c1f278b823f33d89d3e7076364abb0aa2cf30b67.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1126/science.aat4595"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> sciencemag.org </button> </a>

Intelligent Clinical Decision Support to Improve Safe Opioid Management of Chronic Noncancer Pain in Primary Care

Eboni G Price-Haywood, Wanda Robinson, Jewel Harden-Barrios, Jeffrey Burton, Todd Burstain
<span title="">2018</span> <i title="Ochsner Journal"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/yip5ptwddnedjojk3hrj5f3xsi" style="color: black;">Ochsner Journal</a> </i> &nbsp;
We describe the implementation of electronic medical record clinical decision support (EMR CDS) for opioid management of chronic noncancer pain in an integrated delivery system.  ...  equivalent of prescribed opioids.  ...  The authors wish to thank Epic analysts of the Ochsner Health System Information Systems Department for programming the clinical decision support tools and staff members of the Center for Applied Health  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29559866">pmid:29559866</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5855418/">pmcid:PMC5855418</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/r4wqhgzstrc7dgxeoh4v5cl3ei">fatcat:r4wqhgzstrc7dgxeoh4v5cl3ei</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200210125905/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5855418&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/dd/b3/ddb342ef0dd89af33d57c02bcb3d31db6252d57d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855418" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Development of an Emergency Department-Based Intervention to Expand Access to Medications for Opioid Use Disorder in a Medicaid Non-expansion Setting: Protocol for Engagement and Community Collaboration (Preprint)

Lauren A. Walter, LI Y. Li, Joel Rodgers, Jennifer Hess, Rachel Skains, Matthew Delaney, James Booth, Erik P. Hess
<span title="2020-03-15">2020</span> <i title="JMIR Publications Inc."> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vl2vw6ob4raljjnl7vi26tsnsi" style="color: black;">JMIR Research Protocols</a> </i> &nbsp;
When a patient presents to the ED with symptoms of opioid withdrawal, nonfatal opioid overdose, or requesting opioid detoxification, clinicians will consider the diagnosis of OUD using the Diagnostic and  ...  At the time of ED discharge, a peer navigator from a local substance use coordinating center will be engaged to facilitate patient referral to a regional substance abuse coordinating center for longitudinal  ...  have any role during its execution, analyses, interpretation of the data, or decision to submit results.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2196/18734">doi:10.2196/18734</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33913818">pmid:33913818</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8120420/">pmcid:PMC8120420</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/r3uqw4sdgrb4dle4r4ug3pccua">fatcat:r3uqw4sdgrb4dle4r4ug3pccua</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210716025322/https://www.researchprotocols.org/2021/4/e18734/PDF" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/31/fa/31fa948ee55b111d358aa861a91ffbc3bdbb9c17.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2196/18734"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120420" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Safer and more appropriate opioid prescribing: a large healthcare system's comprehensive approach

Jan L. Losby, Joel D. Hyatt, Michael H. Kanter, Grant Baldwin, Denis Matsuoka
<span title="2017-07-14">2017</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vnxakjy6b5gwfgh63w3h6urjlq" style="color: black;">Journal of Evaluation In Clinical Practice</a> </i> &nbsp;
outcomes: a 30% reduction in prescribing opioids at high doses; a 98% reduction in the number of prescriptions with quantities greater than 200 pills; a 90% decrease in the combination of an opioid prescription  ...  Health care systems are taking steps to address the opioid overdose epidemic by implementing policy and practice interventions to mitigate the risks of long-term opioid therapy.  ...  ACKNOWLEDGEMENTS The authors would like to thank and acknowledge the help and contributions of Gene Nakagawa, Gene Chiu, and Patricia L. Gray with Kaiser Permanente Pharmacy; and Steven G.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/jep.12756">doi:10.1111/jep.12756</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28707421">pmid:28707421</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4wbhebsfy5fhjjn4ir5cdyo5qm">fatcat:4wbhebsfy5fhjjn4ir5cdyo5qm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190713154106/https://onlinelibrary.wiley.com/doi/pdf/10.1111/jep.12756" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ca/49/ca4964d0672560879e5a9547919ae38ef73ad462.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/jep.12756"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Optimizing Opioid Abuse Prevention Strategies: Role of Pharmacist in Safe Dispensing

M. Anusree, Pravina Mohan, P. Reshma, Zuhara Mariyam
<span title="2021-09-23">2021</span> <i title="Sciencedomain International"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ztbly42ph5fitd3xnq3ekswtbe" style="color: black;">Journal of Pharmaceutical Research International</a> </i> &nbsp;
All patients who require legitimate and effective pain management through the use of opioids must have access to them.  ...  Recognising "red flag" actions that may suggest opioid abuse; using tests to determine a patient's risk of opioid abuse; collaborating with other health-care providers to plan a patient's treatment; knowing  ...  Patients, pharmacists, and prescribers are all at risk of dying from an opioid overdose.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.9734/jpri/2021/v33i44b32675">doi:10.9734/jpri/2021/v33i44b32675</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/afgouwkkgvbzlihnqn5ffuww5q">fatcat:afgouwkkgvbzlihnqn5ffuww5q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210930160658/https://www.journaljpri.com/index.php/JPRI/article/download/32675/61463" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/54/8b/548b86164013749b88e4171de87c894343293bc7.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.9734/jpri/2021/v33i44b32675"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Naloxone-does over-antagonism matter? Evidence of iatrogenic harm after emergency treatment of heroin/opioid overdose

Joanne Neale, John Strang
<span title="2015-07-30">2015</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/l3xaekn46nb55emj7apk4b3s3a" style="color: black;">Addiction</a> </i> &nbsp;
to counter the naloxone effects.  ...  Evidence of iatrogenic harm after emergency treatment of heroin/opioid overdose ', Addiction 110, 1644---52 RUNNING HEAD: Naloxone -does over-antagonism matter?  ...  is uncertain when hospital admission does not occur after naloxone administration for acute opioid toxicity 23 , clinical algorithms to support discharge decisionmaking have been developed  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/add.13027">doi:10.1111/add.13027</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26119038">pmid:26119038</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/v4fzgahv3fd55ngz3mpd6qqjgy">fatcat:v4fzgahv3fd55ngz3mpd6qqjgy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200322173856/https://kclpure.kcl.ac.uk/portal/files/68941642/Neale_Strang_Naloxone_290515.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f0/e3/f0e38a700aa567da324b95efe6b7e68616dec81a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/add.13027"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>
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