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Effects of Transcranial Direct Current Stimulation on GABA and Glutamate in Children: A Pilot Study [article]

Chidera Nwaroh, Adrianna Giuffre, Lauran Cole, Tiffany Bell, Helen Carlson, Frank P MacMaster, Adam Kirton, Ashley D Harris
<span title="2019-09-05">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that safely modulates brain excitability and has therapeutic potential for many conditions.  ...  This study examined GABA and Glx in response to conventional anodal tDCS (a-tDCS) and high definition tDCS (HD-tDCS) targeting the M1 in a pediatric population.  ...  Introduction Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation in which a weak electrical current is passed between two electrodes placed on the scalp.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/759290">doi:10.1101/759290</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jnxa4m2gsffzxhwvmjpjqnn434">fatcat:jnxa4m2gsffzxhwvmjpjqnn434</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200310233333/https://www.biorxiv.org/content/biorxiv/early/2019/09/05/759290.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/57/df/57df1de198a9739eea6c9d6a7c45f71e7ed2f60b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/759290"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Effects of Transcranial Direct Current Stimulation on GABA and Glx in Children: A pilot study

Chidera Nwaroh, Adrianna Giuffre, Lauran Cole, Tiffany Bell, Helen L. Carlson, Frank P. MacMaster, Adam Kirton, Ashley D. Harris, Benjamin Thompson
<span title="2020-01-07">2020</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that safely modulates brain excitability and has therapeutic potential for many conditions.  ...  This study examined GABA and Glx in response to conventional anodal tDCS (a-tDCS) and high definition tDCS (HD-tDCS) targeting the M1 in a pediatric population.  ...  Effects of Transcranial Direct Current Stimulation on GABA and Glx in Children Discussion Several adult studies have shown that single [52, 53] or multiple session [37,54] tDCS paired with training  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0222620">doi:10.1371/journal.pone.0222620</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31910218">pmid:31910218</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6946135/">pmcid:PMC6946135</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zewydbmsgbdxzhi34v4fgcuugi">fatcat:zewydbmsgbdxzhi34v4fgcuugi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210427174317/https://prism.ucalgary.ca/bitstream/handle/1880/112934/10.1371-journal.pone.0222620.pdf;jsessionid=4C037C6D6D255D209992E08BD7A0E379?sequence=1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7e/50/7e5062373ac798cc04277819bf093d1b2b5249c4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0222620"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946135" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Transient Changes in Brain Metabolites after Transcranial Direct Current Stimulation in Spastic Cerebral Palsy: A Pilot Study

Paradee Auvichayapat, Benchaporn Aree-uea, Narong Auvichayapat, Warinthorn Phuttharak, Taweesak Janyacharoen, Orathai Tunkamnerdthai, Wuttisak Boonphongsathian, Niran Ngernyam, Keattichai Keeratitanont
<span title="2017-07-31">2017</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4kchoxo3jrfubkck3y7nfncina" style="color: black;">Frontiers in Neurology</a> </i> &nbsp;
Anodal transcranial direct current stimulation (tDCS) in patients with muscle spasticity is known to result in significant improvement in spastic tone (p < 0.001).  ...  This pilot study aimed to investigate the effect of anodal tDCS upon brain metabolites in the left basal ganglia and ipsilateral primary motor cortex (M1) in children with spastic cerebral palsy (CP).  ...  Thus, we were not able to evaluate the long-term effects of stimulation.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fneur.2017.00366">doi:10.3389/fneur.2017.00366</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28824525">pmid:28824525</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5534437/">pmcid:PMC5534437</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/udk2h6oqabdjfhkpeeispb3jje">fatcat:udk2h6oqabdjfhkpeeispb3jje</a> </span>
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Influence of Repetitive Transcranial Magnetic Stimulation on Human Neurochemistry and Functional Connectivity: A Pilot MRI/MRS Study at 7 T

Gröhn Heidi, Gillick Bernardette, Tkac Ivan, Bednarik Petr, Macali Daniele, Deelchand Dinesh, Leffler-McCabe Michael, MacKinnon Colum, Lynn Eberly, Mangia Silvia
<span title="2019-11-27">2019</span> <i title="Zenodo"> Zenodo </i> &nbsp;
This pilot study investigated the effects of rTMS on the primary motor cortex using pre and post MRS and rsfMRI assessments at 7 T.  ...  Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation method commonly used in the disciplines of neuroscience, neurology, and neuropsychiatry to examine or modulate brain  ...  ACKNOWLEDGMENTS We are grateful to the study coordinator and participants in the study who thereby made this research possible. We are also grateful to Dr.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5281/zenodo.5717319">doi:10.5281/zenodo.5717319</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/nnzi3feilzgyzj7rz2op6xewam">fatcat:nnzi3feilzgyzj7rz2op6xewam</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220130160914/https://zenodo.org/record/5717320/files/Grohn_Gillick_Fontiers_Neurosci_2019.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/09/58/09584c6d6c2997880a57b3fb447678df00286e37.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5281/zenodo.5717319"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> zenodo.org </button> </a>

Influence of Repetitive Transcranial Magnetic Stimulation on Human Neurochemistry and Functional Connectivity: A Pilot MRI/MRS Study at 7 T

Heidi Gröhn, Bernadette T. Gillick, Ivan Tkáč, Petr Bednařík, Daniele Mascali, Dinesh K. Deelchand, Shalom Michaeli, Gregg D. Meekins, Michael J. Leffler-McCabe, Colum D. MacKinnon, Lynn E. Eberly, Silvia Mangia
<span title="2019-11-27">2019</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wrk3kouosrhcxiprcbguskdipu" style="color: black;">Frontiers in Neuroscience</a> </i> &nbsp;
This pilot study investigated the effects of rTMS on the primary motor cortex using pre and post MRS and rsfMRI assessments at 7 T.  ...  Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation method commonly used in the disciplines of neuroscience, neurology, and neuropsychiatry to examine or modulate brain  ...  ACKNOWLEDGMENTS We are grateful to the study coordinator and participants in the study who thereby made this research possible. We are also grateful to Dr.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnins.2019.01260">doi:10.3389/fnins.2019.01260</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31827419">pmid:31827419</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6890551/">pmcid:PMC6890551</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xs6gx4636ffitpxpdmhau7zs44">fatcat:xs6gx4636ffitpxpdmhau7zs44</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191206110602/https://fjfsdata01prod.blob.core.windows.net/articles/files/476844/pubmed-zip/.versions/1/.package-entries/fnins-13-01260/fnins-13-01260.pdf?sv=2015-12-11&amp;sr=b&amp;sig=ZsWc3DYFqLmX1vpjhttc4VIIxLC%2BzJuLCvNXf8pxgYE%3D&amp;se=2019-12-06T11%3A06%3A31Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fnins-13-01260.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4c/74/4c7476765d366de6b767a4c823c8c6b7c379d397.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnins.2019.01260"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890551" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The role of MRS-assessed GABA in human behavioral performance

Hong Li, Kirstin-Friederike Heise, Sima Chalavi, Nicolaas A.J. Puts, Richard A.E. Edden, Stephan P. Swinnen
<span title="2022-02-08">2022</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/fptky5bef5gmpjh2fugyz6i3yq" style="color: black;">Progress in Neurobiology</a> </i> &nbsp;
Across all studies, the effects of GABA levels on behavioral performance point to generic and partially independent functions that refer to distinctiveness, interference suppression and cognitive flexibility  ...  On the other hand, lower baseline GABA levels may support a reduction of inhibition, leading to higher cognitive flexibility. These effects are task-dependent and appear to be mediated by age.  ...  ) in a sample of airplane pilot trainees and non-trainees. 3.3.2.4.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.pneurobio.2022.102247">doi:10.1016/j.pneurobio.2022.102247</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/35149113">pmid:35149113</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3lcoaxvwkbe5lgw44dxf2s3qpq">fatcat:3lcoaxvwkbe5lgw44dxf2s3qpq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220302233953/https://kclpure.kcl.ac.uk/portal/files/168900416/1_s2.0_S0301008222000338_main.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ea/85/ea855853ffcb51061921d4fc578ca02c24b1113b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.pneurobio.2022.102247"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a>

Transcranial Magnetic Stimulation in Tourette Syndrome: A Historical Perspective, Its Current Use and the Influence of Comorbidities in Treatment Response

Marco Grados, Rachel Huselid, Laura Duque-Serrano
<span title="2018-07-06">2018</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/5hwrtdnkjvclroyxzt4ty5ijb4" style="color: black;">Brain Sciences</a> </i> &nbsp;
This review will examine all published clinical trials employing transcranial magnetic stimulation (TMS) to ameliorate tics, and discuss a framework for the pathophysiology of TS in relation to electrical  ...  TMS can be used as an effective tool to explore the psychophysiology of TS and potentially provide a therapeutic option.  ...  The latter hypothesis may lead to further studies in neuroplasticity effects of TMS in TS, based on the the long-term potentiation (LTP)-like and long-term depression (LTD)-like effects of brain stimulation  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/brainsci8070129">doi:10.3390/brainsci8070129</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29986411">pmid:29986411</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6071080/">pmcid:PMC6071080</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ek7rz32ry5cr7m74wkcmb5n66m">fatcat:ek7rz32ry5cr7m74wkcmb5n66m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190223070021/http://pdfs.semanticscholar.org/412a/95946a08ec7411036ddfe3bbb593c6c4dbfa.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/41/2a/412a95946a08ec7411036ddfe3bbb593c6c4dbfa.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/brainsci8070129"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071080" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Transcranial magnetic stimulation and magnetic resonance spectroscopy: opportunities for a bimodal approach in human neuroscience

Koen Cuypers, Anouk Marsman
<span title="2020-09-25">2020</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Over the last decade, there has been an increasing number of studies combining transcranial magnetic stimulation (TMS) and magnetic resonance spectroscopy (MRS).  ...  In this review, we provide an overview of studies performed in healthy and patient populations combining MRS and TMS, both as a measurement tool and as an intervention.  ...  Stephan Swinnen and Dr. Axel Thielscher for a critical reading of the manuscript.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2020.117394">doi:10.1016/j.neuroimage.2020.117394</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32987106">pmid:32987106</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pmsl4gz33jfsdknyfv7seoiqre">fatcat:pmsl4gz33jfsdknyfv7seoiqre</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210717193821/https://lirias2repo.kuleuven.be/bitstream/handle/123456789/671616/Cuypers%20&amp;%20Marsman%20NeuroImage%20(2020).pdf;jsessionid=1EF5ABA1AA977B3D5AECF1756705B7A4?sequence=2" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/9f/ed/9feddb4cfeab44f7c0870a2e5f7e57caac9b5ff9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2020.117394"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a>

Predicting behavioural response to TDCS in chronic motor stroke

Jacinta O'Shea, Marie-Hélène Boudrias, Charlotte Jane Stagg, Velicia Bachtiar, Udo Kischka, Jakob Udby Blicher, Heidi Johansen-Berg
<span title="">2014</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Transcranial direct current stimulation (TDCS) of primary motor cortex (M1) can transiently improve paretic hand function in chronic stroke.  ...  Both excitatory (Anodal) stimulation of ipsilesional M1 and inhibitory (Cathodal) stimulation of contralesional M1 can speed simple reaction time.  ...  Funders had no role in the study design, data collection, analysis, interpretation, manuscript preparation or decision to submit.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2013.05.096">doi:10.1016/j.neuroimage.2013.05.096</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23727528">pmid:23727528</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3899017/">pmcid:PMC3899017</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/qagbbjfzefamjebkwvin2q27we">fatcat:qagbbjfzefamjebkwvin2q27we</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210717172529/https://escholarship.mcgill.ca/downloads/jw827h57w" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/57/72/57727beaf46e71c8a7db130694dfb1ba90d3c194.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2013.05.096"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899017" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Ketamine as a Fast Acting Antidepressant: Current Knowledge and Open Questions

Giacomo Salvadore, Jaskaran B. Singh
<span title="2013-04-12">2013</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zpqdq5klqvdtjneti6asqutzyq" style="color: black;">CNS Neuroscience &amp; Therapeutics</a> </i> &nbsp;
They relate to the safe and effective use of ketamine in patients with mood disorders regarding the optimal dose range, modality and method of administration for acute and long-term maintenance of effect  ...  While pilot clinical studies are promising, a number of critical questions still remain unanswered.  ...  Conflict of Interest Giacomo Salvadore and Jaskaran Singh are both employees of Janssen Pharmaceuticals, who supported this manuscript and is currently investigating ketamine and esketamine in TRD.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/cns.12103">doi:10.1111/cns.12103</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23578128">pmid:23578128</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/bjkb2cd2njaadmfveqbvtl2ye4">fatcat:bjkb2cd2njaadmfveqbvtl2ye4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170808192757/http://www.thblack.com/links/RSD/CNSNeurosciTher2013_19_428_antidepressant.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/25/7a/257a821b75218c861758e8bcfb9aaf6ee2f3eed8.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/cns.12103"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Therapeutic Potentials of Ketamine and Esketamine in Obsessive–Compulsive Disorder (OCD), Substance Use Disorders (SUD) and Eating Disorders (ED): A Review of the Current Literature

Giovanni Martinotti, Stefania Chiappini, Mauro Pettorruso, Alessio Mosca, Andrea Miuli, Francesco Di Carlo, Giacomo D'Andrea, Roberta Collevecchio, Ilenia Di Muzio, Stefano L. Sensi, Massimo Di Giannantonio
<span title="2021-06-27">2021</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/5hwrtdnkjvclroyxzt4ty5ijb4" style="color: black;">Brain Sciences</a> </i> &nbsp;
Further studies are needed in order to better clarify the many unknowns related to the use of both ketamine and esketamine in SUD, ED and OCD, and to understand their long-term effectiveness.  ...  A comprehensive and updated overview of the literature regarding the pharmacological mechanisms of action of both ketamine and esketamine, as well as their therapeutic advantages over current treatments  ...  Conflicts of  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/brainsci11070856">doi:10.3390/brainsci11070856</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/tenupy7o6fgp5nygjuhc4w6yre">fatcat:tenupy7o6fgp5nygjuhc4w6yre</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210630002741/https://res.mdpi.com/d_attachment/brainsci/brainsci-11-00856/article_deploy/brainsci-11-00856.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4d/60/4d60532da6d94b1c2e590c067b074be29725a1f4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/brainsci11070856"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a>

Novel glutamatergic agents for major depressive disorder and bipolar disorder

Rodrigo Machado-Vieira, Lobna Ibrahim, Ioline D. Henter, Carlos A. Zarate
<span title="">2012</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/f6dbxxkodjb5znhnejrfaub4au" style="color: black;">Pharmacology, Biochemistry and Behavior</a> </i> &nbsp;
Mood disorders such as major depressive disorder (MDD) and bipolar disorder (BPD) are common, chronic, recurrent mental illnesses that affect the lives and functioning of millions of individuals worldwide  ...  Growing evidence suggests that the glutamatergic system is central to the neurobiology and treatment of these disorders.  ...  Zarate is listed among the inventors on a patent application submitted for the use of ketamine in depression. He has assigned his rights on the patent to the US government.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.pbb.2011.09.010">doi:10.1016/j.pbb.2011.09.010</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21971560">pmid:21971560</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3253881/">pmcid:PMC3253881</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dynd2fyslbbhxcj7tjwe4j3juu">fatcat:dynd2fyslbbhxcj7tjwe4j3juu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200429211713/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3253881&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a6/ef/a6ef00f21766a8ad53865fc88c0378831e436185.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.pbb.2011.09.010"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253881" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Impact of Transcranial Direct Current Stimulation and Cognitive Training on Frontal Lobe Neurotransmitter Concentrations

Stacey Alvarez-Alvarado, Emanuel M Boutzoukas, Jessica N Kraft, Andrew O'Shea, Aprinda Indahlastari, Alejandro Albizu, Nicole R Nissim, Nicole D Evangelista, Ronald Cohen, Eric C Porges, Adam J Woods
<span title="2021-10-21">2021</span>
Objective: This study examines the impact of transcranial direct current stimulation (tDCS) combined with cognitive training on neurotransmitter concentrations in the prefrontal cortex.  ...  Glutamine/glutamate (Glx) and gamma-aminobutyric acid (GABA) concentrations via proton magnetic resonance spectroscopy were evaluated at baseline and at the end of 2-week intervention.  ...  INTRODUCTION Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that applies a weak and constant electric current via electrodes placed on the scalp over target  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2021.761348">doi:10.3389/fnagi.2021.761348</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34744698">pmid:34744698</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8568306/">pmcid:PMC8568306</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/76jvxxv5pjaqthu6vk6qgdmgem">fatcat:76jvxxv5pjaqthu6vk6qgdmgem</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20211120193039/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8568306&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f5/59/f55985edb9e1ec5d2428b10fa16861f9d6abf4c6.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2021.761348"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568306" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Using magnetic resonance imaging to assess visual deficits: a review

Holly D. H. Brown, Rachel L. Woodall, Rebecca E. Kitching, Heidi A. Baseler, Antony B. Morland
<span title="2016-04-25">2016</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/u2jz6tegergrlpxqdega73otv4" style="color: black;">Ophthalmic &amp; physiological optics</a> </i> &nbsp;
Disclosure The authors report no conflicts of interest and have no proprietary interest in any of the materials mentioned in this article.  ...  Acknowledgements The authors acknowledge with thanks Fight for Sight project grant (1523/1524), the Wellcome Trust for its Institutional Strategic Support Fund, awarded to the University of York, and the  ...  Levodopa has been piloted as a potential treatment for amblyopia. 188, 189 Another approach is to apply transcranial direct current stimulation (TDCS) to visual cortex 28 .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/opo.12293">doi:10.1111/opo.12293</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27112223">pmid:27112223</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4855621/">pmcid:PMC4855621</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/bcmlrz72ljdtvh7m2whuanjsr4">fatcat:bcmlrz72ljdtvh7m2whuanjsr4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180724225016/http://eprints.whiterose.ac.uk/100175/8/Brown_et_al_2016_Ophthalmic_and_Physiological_Optics.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b0/a3/b0a3f4a9f76aad3f580f344f08eb6e1607b69202.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/opo.12293"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855621" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

ACNP 55th Annual Meeting: Panels, Mini-Panels and Study Groups

<span title="">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zscwnf3bera7vcvkm7bgnh2sbu" style="color: black;">Neuropsychopharmacology</a> </i> &nbsp;
Transcranial direct current stimulation (tDCS), specifically, induces weak intensity and spatially diffuse electric fields in the brain.  ...  treatments of long-term adverse effects of marijuana use.  ...  Recent studies have identified a direct impact of presenilin mutations on the regulation of presynaptic function leading to alterations in synaptic plasticity.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/npp.2016.239">doi:10.1038/npp.2016.239</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wg7pyurlzvhp7bvlmlbxtkunl4">fatcat:wg7pyurlzvhp7bvlmlbxtkunl4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191112051255/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5149583&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/46/ce/46ce540ffbae701ae73304cb1adf90d02cb1c2fd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/npp.2016.239"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>
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