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Optical coherence tomography angiography in diabetic retinopathy: a review of current applications
2019
Eye and Vision
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length of vessels, vascular architecture and area of the foveal avascular zone. ...
OCTA may potentially serve as a useful non-invasive imaging tool in the diagnosis and monitoring of diabetic retinopathy and maculopathy in the future. ...
Acknowledgements
Not applicable Authors' contributions All authors contributed equally in this work. All authors read and approved the final manuscript. ...
doi:10.1186/s40662-019-0160-3
pmid:31832448
pmcid:PMC6859616
fatcat:znr3qxn6obbmvbihiyzuy5tfqq
Fast 3-dimensional estimation of the Foveal Avascular Zone from OCTA
[article]
2020
arXiv
pre-print
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2021 accepted arXiv:2012.09945v2 fatcat:ktjqlfkrfremjjuncxc7ggwupi
The area of the foveal avascular zone (FAZ) from en face images of optical coherence tomography angiography (OCTA) is one of the most common measurement based on this technology. ...
Then, the measurements were analyzed using linear mixed effect models to identify differences between three groups of eyes: healthy, diabetic without diabetic retinopathy (DR) and diabetic with DR. ...
., “Early diagnosis of diabetic retinopathy in octa images
based on local analysis of retinal blood vessels and foveal avascular ...
arXiv:2012.09945v1
fatcat:5rag3qy425dltdtgrspmxnnt7q
QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES FOR OBJECTIVE CLASSIFICATION AND STAGING OF DIABETIC RETINOPATHY
2018
Retina
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Six quantitative features, that is, blood vessel tortuosity, blood vascular caliber, vessel perimeter index, blood vessel density, foveal avascular zone area, and foveal avascular zone contour irregularity ...
One hundred and twenty OCTA images from 60 NPDR (mild, moderate, and severe stages) patients and 40 images from 20 control subjects were used for this study conducted in a tertiary, subspecialty, academic ...
Mark Janowicz and Ms. Andrea Degillio (Eye and Ear Infirmary, University of Illinois at Chicago) for technical support of data acquisition. ...
doi:10.1097/iae.0000000000002373
pmid:30383712
pmcid:PMC6494740
fatcat:qqkezj67qfcqvpk6biglp62cly
Parafoveal OCT Angiography Features in Diabetic Patients without Clinical Diabetic Retinopathy: A Qualitative and Quantitative Analysis
2017
Journal of Ophthalmology
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Quantitative analysis measured foveal avascular zone (FAZ) size, parafoveal capillary density, and enlargement coefficient of FAZ between SCP and DCP. Results. ...
To evaluate the capacity of OCT angiography (OCTA) for detecting infraclinical lesions in parafoveal capillaries in diabetic patients without diabetic retinopathy (DR). Methods. ...
Acknowledgments The authors would like to thank the whole care team of the Department of Ophthalmology of Creteil Hospital for the achievement of this study. ...
doi:10.1155/2017/8676091
pmid:28761762
pmcid:PMC5518527
fatcat:5mqn2jjaxzconbxgqgi5si2rie
Linking Retinal Microvasculature Features With Severity of Diabetic Retinopathy Using Optical Coherence Tomography Angiography
2016
Investigative Ophthalmology and Visual Science
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Local fractal analysis was applied to the superficial and deep retinal OCTA images. ...
Foveal avascular zone area (FAZ in mm 2 ); vessel density (%); spacing between large vessels (%); and spacing between small vessels (%) were analyzed. ...
Acknowledgments The present imaging study was done as part of a collaborative characterization of a large cohort of diabetic retinopathy patients with Genentech (San Francisco, CA, USA). ...
doi:10.1167/iovs.15-18901
pmid:27472275
fatcat:ilb4gnq7rrfufkkxedh2sdgfsu
Optical coherence tomography angiography (OCTA) flow speed mapping technology for retinal diseases
2018
Expert Review of Medical Devices
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Various quantitative metrics have been developed, such as foveal avascular zone area and vessel density. ...
diabetic retinopathy. ...
, the Foundation for the National Institutes of Health (NIH 5-R01-EY011289-31), and the Macula Vision Research Foundation. ...
doi:10.1080/17434440.2018.1548932
pmid:30460869
pmcid:PMC6529293
fatcat:adrade4e7vhsbkv6y5moul3sve
Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy
2020
Journal of Clinical Medicine
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Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by generating 3-dimensional images based on the motion contrast of circulating blood ...
Diabetic retinopathy (DR) is a common complication of diabetes mellitus that disrupts the retinal microvasculature and is a leading cause of vision loss globally. ...
Conflicts of Interest: The author(s) declare that they have no competing interests. ...
doi:10.3390/jcm9061723
pmid:32503234
pmcid:PMC7357089
fatcat:vpgbqmpvorbbzdcazfxkzbddu4
Human retinal microvascular imaging using adaptive optics scanning light ophthalmoscopy
2016
International Journal of Retina and Vitreous
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Conclusion: This review will briefly summarize the abilities of in vivo human retinal microvasculature imaging in healthy controls, as well as patients with diabetic retinopathy, retinal vein occlusion ...
microvascular structure, measurements of blood flow velocity, and microvascular network mapping. ...
Shadow of a non-perfused blood vessel is indicated by a white arrow. b Visualization of the non-perfusion blood vessel on nonconfocal AOSLO structural image. c Superimposed composite of a (in red) and ...
doi:10.1186/s40942-016-0037-8
pmid:27847629
pmcid:PMC5088465
fatcat:b2egdryz2ngwbmxq3qegte7mry
Optical coherence tomography angiography versus fluorescein angiography in diagnosis of ischemic diabetic maculopathy
2022
International Journal of Health Sciences
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diagnosed according to the Early Treatment Diabetic Retinopathy Study (ETDRS) classification based on Foveal avascular zone (FAZ) parameters. ...
Objectives: To compare between the use of Fundus Fluorescein Angiography (FFA) and Optical Coherence Tomography Angiography (OCTA) in the diagnosis and quantification of diabetic macular ischemia (DMI) ...
ischemia (DMI) based on Foveal avascular zone (FAZ) parameters. ...
doi:10.53730/ijhs.v6ns7.11494
fatcat:jdte5t4455f4dm42noizewin6e
Assessment of capillary dropout in the superficial retinal capillary plexus by optical coherence tomography angiography in the early stage of diabetic retinopathy
2018
BMC Ophthalmology
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To assess capillary dropout in the superficial retinal capillary plexus (SCP) by optical coherence tomography angiography (OCTA) in the early stage of diabetic retinopathy (DR). ...
Conclusions: In the early stage of NPDR, retinal capillary dropout and retinal thickness changes can be clearly captured and analyzed by OCTA. ...
Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. ...
doi:10.1186/s12886-018-0778-2
pmid:29739379
pmcid:PMC5941753
fatcat:mly63uqlzne3xmwt3spwokoija
Plexus-Specific Detection of Retinal Vascular Pathologic Conditions with Projection-Resolved OCT Angiography
2018
Ophthalmology Retina
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In cases of diabetic retinopathy, retinal vessel occlusion, and retinitis pigmentosa, PR-OCTA detected retinal nonperfusion regions within deeper retinal plexuses not visualized by conventional OCTA. ...
The volumetric scans were segmented and visualized on different plexuses. Main Outcome Measures-Qualitative observation of vascular abnormalities on both crosssectional and en face PR-OCTA images. ...
with an irregular foveal avascular zone. ...
doi:10.1016/j.oret.2017.11.010
pmid:30148244
pmcid:PMC6106769
fatcat:zxnlcbklfndkhddeob7ugcw56e
Association of macular perfusion status with microvascular parameters up to the far periphery in diabetic retinopathy using multimodal imaging
2020
International Journal of Retina and Vitreous
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Foveal avascular zone (FAZ) and vessel density from the superficial (SCP) and deep capillary plexus (DCP) were assessed on optical coherence tomography angiography (OCTA) scans (Topcon, DRI-OCT Triton) ...
stages of diabetic retinopathy (DR). ...
Acknowledgements The authors thank the collaborators at the Vienna Clinical Trial Centre (Medical University of Vienna, Austria). ...
doi:10.1186/s40942-020-00253-w
pmid:33292856
fatcat:6p63bv7l4zgr3bg4b3kbepecie
Cognitive decline in older adults: What can we learn from optical coherence tomography (OCT)-based retinal vascular imaging?
2021
Journal of The American Geriatrics Society
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The foveal avascular zone (FAZ) area was also estimated. Image quality was assessed by trained graders at a reading center. ...
Optical coherence tomographic angiography (OCTA) was used to capture vessel density (VD) from a 6 × 6 mm scan of the macula in several vascular layers from 2017 to 2019. ...
The foveal avascular zone (FAZ) area, 41 defined as the region in the fovea devoid of retinal blood vessels, was also estimated from 3 Â 3 mm 2 images. ...
doi:10.1111/jgs.17272
pmid:34009667
pmcid:PMC8440348
fatcat:ehorcr2sqzdltjiae3gcewr5je
Association Between the Severity of Diabetic Retinopathy and Optical Coherence Tomography Angiography Metrics
2021
Frontiers in Endocrinology
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OCTA metrics based on the proposed segmentation method were validated to be reliable for further analysis of the relationship between OCTA metrics and diabetes and the severity of diabetic retinopathy. ...
Changes in vessel morphology are influenced by systemic risk factors. However, there is a lack of analysis of the relationship between OCTA metrics and systemic risk factors. ...
University, and all the volunteers for their help. ...
doi:10.3389/fendo.2021.777552
pmid:34956088
pmcid:PMC8702651
fatcat:5odrugg33fd4tdwz7urdafms3a
Macular Vessel Density in Diabetic Retinopathy Patients: How Can We Accurately Measure and What Can It Tell Us?
2021
Clinical Ophthalmology
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In this non-systematic review, the measurement of macular vessel density in diabetic retinopathy and the reasons for its importance in the diagnosis and management of patients with diabetes and varying ...
Macular vessel density is one of the quantitative metrics that can be obtained from OCTA images. ...
This includes foveal avascular zone (FAZ) area and perimeter, FAZ contour irregularity, blood vessel tortuosity (BVT), blood vessel caliber (BVC), vessel perimeter index (VPI), fractal dimension (FD) and ...
doi:10.2147/opth.s272328
pmid:33880011
pmcid:PMC8053507
fatcat:t5zzit7gebhwpdvzjjgffuz27a
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