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Dynamical compensation and structural identifiability of biological models: Analysis, implications, and reconciliation

Alejandro F. Villaverde, Julio R. Banga, Herbert Sauro
2017 PLoS Computational Biology  
Our analyses enable the use of the new concept of dynamical compensation in the context of parameter identification, and reconcile it with the desirable property of structural identifiability.  ...  Here we show that, according to its original definition, dynamical compensation is equivalent to lack of structural identifiability.  ...  Dynamical compensation and structural unidentifiability in the βIG model.  ... 
doi:10.1371/journal.pcbi.1005878 pmid:29186132 pmcid:PMC5724898 fatcat:v4n3cy4qgjhyjoir222nrflqz4

Incidental findings in the use of DNA to identify human remains: An ethical assessment

Lisa S. Parker, Alex John London, Jay D. Aronson
2013 Forensic Science International: Genetics  
DNA analysis is increasingly used to identify the remains of victims of conflicts and disasters.  ...  It concludes by considering some implications of this argument for the choice among scientific practices involved in using DNA analysis to identify human remains, as well as for managing non-genetic incidental  ...  Acknowledgments This work was made possible by Grant Number R01 HG005702 from the Ethical, Legal, and Social Implications Research Program of the U.S.  ... 
doi:10.1016/j.fsigen.2012.10.002 pmid:23116722 pmcid:PMC3581719 fatcat:p4efj7ory5cwholz5l2jxjjydi

Surgeon Burnout: Defining, Identifying, and Addressing the New Reality

James Clark Senturk, Nelya Melnitchouk
2019 Clinics in Colon and Rectal Surgery  
Loss of professional control, autonomy, and flexibility; inefficient processes; disjointed workplace relationships and goals; excessive administrative burdens; poor work–life balance; and frustrations  ...  The strong link between surgeons' personal and professional identities can lead to a perfect storm of burnout, depression, compromised patient safety and quality of care, physician job loss and career  ...  which to continually evaluate and improve the dynamic between the worker and the workplace.  ... 
doi:10.1055/s-0039-1692709 pmid:31824232 pmcid:PMC6901360 fatcat:ew4p2x5sjrgyrfcrtte5m6gydq

Computational modeling of stem and progenitor cell kinetics identifies plausible hematopoietic lineage hierarchies

Lisa Bast, Michèle C. Buck, Judith S. Hecker, Robert A.J. Oostendorp, Katharina S. Götze, Carsten Marr
2021 iScience  
An in silico analysis confirmed that, even for strong noise, the classical model can be identified robustly.  ...  and rejected others.  ...  Cell Biol. 19, 271-281.Villaverde, A.F., and Banga, J.R. (2017). Dynamical compensation and structural identifiability of biological models: analysis, implications, and reconciliation. PLoS Comput.  ... 
doi:10.1016/j.isci.2021.102120 pmid:33665548 pmcid:PMC7897991 fatcat:j3z5tvk3hbbsffreqq7i3mvoam

Identifying Conflict and Violence in Micro-Level Surveys

Tilman Brück, Patricia Justino, Philip Verwimp, Alexandra Avdeenko
2010 Social Science Research Network  
The overall goal of the report is to increase the capacity of researchers and policy makers to identify comparatively, and across time, how individuals, households and communities are affected by violent  ...  in order to deepen the understanding of the nature of violent conflict and the channels whereby conflict and violence affect the welfare characteristics and choices of individuals and households in conflict  ...  Other research work includes the measurement of non-monetary dimensions of inequality and their effects on social development and economic growth, the measurement and modelling of poverty (static and dynamic  ... 
doi:10.2139/ssrn.1650612 fatcat:rxtdxap3t5gqveyhas5npmpnqu

Identifying 'the invention' in Inventorship Disputes

Moshood Abdussalam
2014 SCRIPTed: A Journal of Law, Technology & Society  
This paper is concerned only with the definition and identification of "the invention" in patent entitlement disputes.  ...  the technical contribution furnished; and e) the specification avoids inequitable assertions of entitlement in inventorship disputes.  ...  A synopsis on the history of joint inventorship in the USA is firstly necessary to help understand the dynamics and peculiarities of the US position.  ... 
doi:10.2966/scrip.110114.38 fatcat:h5hx3s7hozcavmdx75vjwcobn4

Identifying routes to remedy for violations of economic, social and cultural rights

Katie Boyle, Edel Hughes
2017 International Journal of Human Rights  
This article examines the status of economic, social and cultural (ESC) rights in Scotland and identifies routes to remedy for violations of these rights.  ...  The evidence identified that protection mechanisms for socio-economic rights in Scotland are either insufficient or non-existent.  ...  playing a part in restorative justice or reconciliation. 38 The importance of a coherent structure to enable both the existence of and access to that Convention requires that a remedy 'be such as to  ... 
doi:10.1080/13642987.2017.1390304 fatcat:kcdjbt2v4rgepiz3jwibw4yhu4

Neurotoxicity. Identifying and controlling poisons in the nervous system

1993 Environment International  
J., and Joy, R. M., Pesticides and Neurological Disease (Boca Raton, FL: CRC Press, 1982).  ...  Grasso, P., et al., "Neurophysiological and Psychological Disorders and Occupational Exposure to Organic Solvents, " Food and Chemical Toxicity 22:819-852, 1984. Gray, D.  ...  The elderly are more susceptible to certain neurotoxic substances because decline in the structure and function of the nervous system with age limits its ability to respond to or compensate for toxic effects  ... 
doi:10.1016/0160-4120(93)90375-r fatcat:yqkmsjjiyvcl3eps6ke7wzcxlm

Fostering Coexistence Between People and Large Carnivores in Africa: Using a Theory of Change to Identify Pathways to Impact and Their Underlying Assumptions

Sarah M. Durant, Agnese Marino, John D. C. Linnell, Alayne Oriol-Cotterill, Stephanie Dloniak, Stephanie Dolrenry, Paul Funston, Rosemary J. Groom, Lise Hanssen, Jane Horgan, Dennis Ikanda, Audrey Ipavec (+7 others)
2022 Frontiers in Conservation Science  
Our analysis draws on the experience of coauthors, who are scientists and practitioners, and on literature from conservation, political ecology, and anthropology to explore the challenges, local realities  ...  Overall, the model provides a flexible and practical framework that can be adapted to dynamic local socio-ecological contexts.  ...  ) and damage compensation and insurance schemes (Dickman et al., 2011) .  ... 
doi:10.3389/fcosc.2021.698631 fatcat:7fbk6f2xjzfsranv353r7p2rye

Problematising the discourses of the dominant: whiteness and reconciliation

Meredith J. Green, Christopher C. Sonn
2006 Journal of Community and Applied Social Psychology  
To do this we identify connections between the discourses used by white Australians involved in  ...  The connections between hegemonic and ideological forces, such as white supremacy, patriarchy and class elitism within macro-dynamics of structures and micro-dynamics of everyday life are then seen and  ...  These discourses, in part, describe the power of whiteness in the context of Reconciliation and we have used them to illustrate some of the implications they have for Reconciliation and actions towards  ... 
doi:10.1002/casp.882 fatcat:fcrw2ueg5ravtpmsdpncxnhf6q

Reconstructing the social fabric amid ongoing violence: attitudes toward reconciliation and structural transformation in Colombia

Laura K. Taylor, Manuela Nilsson, Brenda Amezquita-Castro
2015 Peacebuilding  
The paper concludes with policy implications that integrate reconciliation and structural transformation to deepen efforts to rebuild the social fabric amid violence.  ...  Given the increase of reconciliation processes initiated amid on-going violence, this study focuses on community reconciliation and its relation to structural transformation, or social reconstruction through  ...  Reconciliation: Rebuilding Social Relations and Transforming Societal Structures With the aim of reconstructing the torn social fabric that results from protracted conflict, a number of dynamic interactions  ... 
doi:10.1080/21647259.2015.1094909 fatcat:77lnz4kl6vexnag7tf3hgsvnje

Who's Sorry Now? Government Apologies, Truth Commissions, and Indigenous Self-Determination in Australia, Canada, Guatemala, and Peru

Jeff Corntassel, Cindy Holder
2008 Human Rights Review  
In this paper, we examine the use of apologies and truth and reconciliation commissions in four countries with significant Indigenous populations: Canada, Australia, Peru and Guatemala.  ...  In each case, the reconciliation mechanism differentiated the goal of reconciliation from an Indigenous self-determination agenda.  ...  implications for Indigenous communities and fails to promote a necessary balance between restitution and reconciliation strategies.  ... 
doi:10.1007/s12142-008-0065-3 fatcat:7b54jcypjrgybmdyjnyjssfcjm

Examining discourses of whiteness and the potential for Reconciliation

Meredith J. Green, Christopher C. Sonn
2005 Journal of Community and Applied Social Psychology  
In particular, we identify spaces for the examination and critique of whiteness within white Australians' discursive negotiations of Reconciliation.  ...  To illustrate this we use the findings from a discourse analysis (Henriques, Hollway, Urwin, Venn, & Walkerdine, 1998) of discussions with white Australians about their involvement in Reconciliation.  ...  Expert analysis The 'expert analysis' discourse was about white reconcilers having knowledge and expertise about the structures and practices of Indigenous communities and cultures.  ... 
doi:10.1002/casp.843 fatcat:asafazzidzhelm2obuuovla4sq

Novel Coronavirus in Cape Town Informal Settlements: Feasibility of using informal dwelling outlines to identify high risk areas for COVID-19 transmission from social distancing perspective. (Preprint)

Lesley Gibson, David Rush
2020 JMIR Public Health and Surveillance  
We will first examine the distance between dwellings and their first, second, and third nearest neighbors and then identify clusters of dwellings in which residents would be unable to effectively practice  ...  This study measures the distance between dwellings in informal settlements in Cape Town to identify the risk of COVID-19 transmission.  ...  The IRM policies were established to ensure a structured approach so as to identify and mitigate risks across the Entity to an acceptable level.  ... 
doi:10.2196/18844 pmid:32250283 fatcat:pd3xoyfopndqniwty4hnkmwi5i

Mutual Blessing [chapter]

2010 Beyond Control  
The advantage of using the concepts of mimetic structures of violence and mimetic structures of blessing as categories of analysis is that it gets away from the discourse of blame which can be another  ...  Since the transformation from mimetic structures of violence to mimetic structures of blessing can be framed as reconciliation, in the next section we will present elements of reconciliation-aspects and  ... 
doi:10.5040/ fatcat:t5tgwpnmlrfbloyg4mn5zksoru
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