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Drug Targetor: a web interface to investigate the human druggome for over 500 phenotypes

Héléna A Gaspar, Christopher Hübel, Gerome Breen
2018 Bioinformatics  
With the aim of using this data to better understand therapeutic mechanisms, we have developed Drug Targetor, a web interface that allows the generation and exploration of drug-target networks of hundreds  ...  We show that Drug Targetor can help prioritize drugs, targets and drug-target interactions for a specific phenotype based on genetic evidence.  ...  In this paper, we present Drug Targetor (drugtargetor.com), a web interface that allows users to browse over 500 GWAS to identify drugs and targets of interest using bipartite drug-gene networks.  ... 
doi:10.1093/bioinformatics/bty982 pmid:30517594 pmcid:PMC6612852 fatcat:f5f6ynf555dzvdcsdw27ixmosa