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What do temporal lobe epilepsy and progressive mild cognitive impairment have in common?

Yvonne Höller, Eugen Trinka
2014 Frontiers in Systems Neuroscience  
Neuroimaging techniques such as volumetric analysis of the hippocampus, entorhinal, and perirhinal cortex show evidence of pathological changes in TLE and are predictive for memory decline in MCI.  ...  These methods together with event-related designs that assess memory functions are highly promising for understanding the mechanisms of memory decline in both TLE and MCI populations.  ...  ACKNOWLEDGMENTS We thank Amy Melissa Lett for language editing and Jonas Potthoff for help in retrieving literature.  ... 
doi:10.3389/fnsys.2014.00058 pmid:24795575 pmcid:PMC3997046 fatcat:5l4xsdzwnvc6tedxrjsb5c4rem

Monday July 3, 2006 15:00-17:00 Hall 3A Discussion Group Session Cognitive dysfunction in children with temporal lobe epilepsy

2006 Epilepsia  
There were no significant changes in mean (±SEM) serum concentrations of testosterone (p = 0.225), SHBG (p = 0.201), or androstenedione (p = 0.394) in either patient group at 6 months after initiation  ...  The number of subjects who completed the study and were seizure-free during weeks 4-40 was 37 (40%) in the LTG group and 46 (50%) in the CBZ group.  ...  Histological analysis revealed that the epileptic rats had increased mossy fibre sprouting in the hippocampus (p < .01).  ... 
doi:10.1111/j.1528-1167.2006.00715_55.x fatcat:as6vr3saobh2noqiutoquvfmni

9TH ECE PROCEEDINGS

2010 Epilepsia  
Purpose: To explore the causative role of PCDH19 gene, located at Xq22, in females with epilepsy.  ...  Seven patients became seizure-free after 28-145 (median 63) days with LTG between 1-7 (median 3) mg/kg and LTG serum levels between 1-5 (median 2) mg/L.  ...  Results: We included 10 patients (8 boys) aged 2.1-7.8 (median 3.7) years at the time when LTG was started in comedication. The onset of MAE had been at 1.5-4.3 (median 2.6) years.  ... 
doi:10.1111/j.1528-1167.2010.02658.x pmid:20590792 fatcat:ylmo7rjtqncydkxeudaib77noy

XXIst Congress of the European Society for Stereotactic and Functional Neurosurgery. Implementing Research in Clinical Applications. Maastricht, The Netherlands, September 17-20, 2014: Abstracts

2014 Stereotactic and Functional Neurosurgery  
There are few reports about similar cases in the literature.  ...  Conclusion: We hope to finish the analysis of samples of 10 PD vs. 10 control cases by the beginning of next year.  ...  Surprisingly, 7-Tesla MR scans did not show any detectable volumetric change between tgHD and WT rats in the brain at 9, 12 and 18 months old of age, despite the volumetric changes observed after histological  ... 
doi:10.1159/000367644 pmid:25247733 fatcat:i6v7nsnacvfv3mjvpvrxmtlkxu

https://dergipark.org.tr/anatomy/issue/44888/558887
Abstracts for the 17th Turkish Neuroscience Congress, 4–7 April 2019, Trabzon, Turkey

2019 Anatomy (International Journal of Experimental and Clinical Anatomy)  
status epilepticus.  ...  disor- methods, including task-related fMRI, diffusion tensor imag- ders.  ... 
doi:10.2399/ana.19.001s fatcat:cxihq27bmbcdzddf4xvqyudqsq

17th Quadrennial Meeting of the World Society for Stereotactic and Functional Neurosurgery. Berlin, Germany, June 26-29, 2017: Abstracts

2017 Stereotactic and Functional Neurosurgery  
However, at 12 months the ITP group showed no change in response rates and maintained a 30.3% overall improvement in Y-BOCS severity scores (20.25±8.8), but the ACING group continued to progress with 60%  ...  Using diffusion tensor imaging (DTI), we segmented the ALIC based on frontal connectivity and used the resulting segmentation to evaluate capsulotomy targeting in OCD.  ...  Hemifacial pain and sensory change following occipital neuralgia may be a symptomatic clue in decision of the exploration of GON.  ... 
doi:10.1159/000478281 pmid:28641280 fatcat:ivcbjloukfgiriry65t37fccm4

Abstracts of the 16th Annual Meeting of The Israel Society for Neuroscience: Eilat, Israel, November 25–27, 2007

2007 Neural Plasticity  
poster presentations, and the program of the meeting is mainly based on the 338 received abstracts which are published in this volume.  ...  The meeting also offers the opportunity for the researchers to exchange information with each other, often leading to the initiation of collaborative studies.  ...  The effects of music background on sleep efficiency, anxiety and depression in Schizophrenia patients  ... 
doi:10.1155/2007/30585 pmid:25148070 pmcid:PMC2366074 fatcat:u4tjfw6shnaxpnzwezieeiqnpm

ACNP 59th Annual Meeting: Poster Session III

2020 Neuropsychopharmacology  
ACNP 59 th Annual Meeting: Poster Session III Conclusions: Among trauma-exposed individuals, those with PTSD show deficits in fear extinction recall to previously threatening stimuli a week after extinction  ...  Methods: Clinical assessments, serum CRP, and diffusion tensor imaging (DTI) data were collected from both a cross-sectional study of chronic trauma (GTP) and as part of a longitudinal study of acutely  ...  Brains from these rats were subsequently prepared for examination by histological analysis.  ... 
doi:10.1038/s41386-020-00892-5 pmid:33279936 pmcid:PMC7735201 fatcat:mip4ywutfnfwvmye4u65i6vgg4

44th Annual Congress of the Canadian Neurological Sciences Federation

2009 Canadian Journal of Neurological Sciences  
Histopathological changes in various subfield of the hippocampus correlated well with pre-operative and ex-vivo imaging changes and the newly proposed measure for MTS.  ...  ), K Petrecca (Montreal) Diffusion tensor imaging-based fiber tracking is a new MRI technology that is being utiliazed to reveal the relationship between the principal white matter tracts and the intracerebral  ...  Six month CTA and MRI showed marked reduction in the mass effect and continued complete occlusion of the aneurysm. She remains neurologically normal.  ... 
doi:10.1017/s0317167100008799 fatcat:p5tedzaxbnczpbm5fashrtpxyi

Quantify Physiological and Structural Changes After a Convulsive Sub-lethal Dose of Soman using MRI and Oxygen Sensors in Rats [article]

Lee, Seung-Hun (Kevin), University Of Calgary, Jeff F. Dunn
2020
At 18-24 hours after soman exposure, changes in qT2 MRI correlated with neurodegenerative markers, with the strongest correlation being in the piriform cor [...]  ...  Additionally, hyperoxygenation was detected during status epilepticus and remained elevated at 24 hours.  ...  The hippocampus CA2, CA3, and dentate gyrus volume were specifically reduced (Chao et al., 2014; Chao et al., 2017) .  ... 
doi:10.11575/prism/38158 fatcat:zklz5bwa7rd4vnqxdopczps7be

PhD PROCEEDINGS ANNUAL ISSUES OF THE DOCTORAL SCHOOL FACULTY OF INFORMATION TECHNOLOGY & BIONICS 2015 PhD PROCEEDINGS ANNUAL ISSUES OF THE DOCTORAL SCHOOL FACULTY OF INFORMATION TECHNOLOGY & BIONICS PhD PROCEEDINGS ANNUAL ISSUES OF THE DOCTORAL SCHOOL FACULTY OF INFORMATION TECHNOLOGY & BIONICS 2015

Pázmány Péter
unpublished
like to thank his supervisor, Miklós Gyöngy (PhD) for the helpful and professional guidance and also thank both his supervisor and Lajos Balogh (PhD) for providing data of mice (examined in this paper  ...  This work was partially supported by the NSF/SRC grant 'Nanoelectronics Beyond 2020' and by a grant from Intel corporation.  ...  Hippocampal regions were reconstructed based on histological assessment of the removed HcFs, and subregions were determined as follows: Cornu Ammonis (CA), Dentate Gyrus (DG), Subiculum (Sub, distal, proximal  ... 
fatcat:odh6qicnh5bbhgv67aukrbq2ty