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Neural Correlates of Freezing of Gait in Parkinson's Disease: An Electrophysiology Mini-Review

J. Sebastian Marquez, S. M. Shafiul Hasan, Masudur R. Siddiquee, Corneliu C. Luca, Virendra R. Mishra, Zoltan Mari, Ou Bai
<span title="2020-11-10">2020</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4kchoxo3jrfubkck3y7nfncina" style="color: black;">Frontiers in Neurology</a> </i> &nbsp;
Parkinson's disease (PD).  ...  One of the biggest unmet needs in the field is the identification of reliable biomarkers that can be construed from real walking scenarios to guide better treatments and validate medical and therapeutic  ...  pathological not physiological beta bursts during gait in Parkinson's disease (111) Walking in place and forward walking comparison of DBS frequency-setting effects while recording STN and EEG  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fneur.2020.571086">doi:10.3389/fneur.2020.571086</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33240199">pmid:33240199</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7683766/">pmcid:PMC7683766</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/weysy6cv6zauddjpvttqw6kehq">fatcat:weysy6cv6zauddjpvttqw6kehq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201111202510/https://fjfsdata01prod.blob.core.windows.net/articles/files/571086/pubmed-zip/.versions/1/.package-entries/fneur-11-571086/fneur-11-571086.pdf?sv=2018-03-28&amp;sr=b&amp;sig=%2F47OM57JasQS3T3WlFUksxWXdaf%2FLfcHEbP%2FVwo%2Fbjw%3D&amp;se=2020-11-11T20%3A25%3A40Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fneur-11-571086.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/57/7a/577a7c17cce5cd72da37d507f2088102c5033f9f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fneur.2020.571086"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683766" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

EEG and MEG primers for tracking DBS network effects

Vladimir Litvak, Esther Florin, Gertrúd Tamás, Sergiu Groppa, Muthuraman Muthuraman
<span title="2020-10-12">2020</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
These studies revealed a set of cortico-subcortical coherent networks functioning at distinguishable physiological frequencies.  ...  This requires, however, the careful consideration of different types of artifacts in the data acquisition and the subsequent analyses.  ...  This study was supported by a grant from German Research Council (DFG; CRC-TR-128, CRC 1193).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2020.117447">doi:10.1016/j.neuroimage.2020.117447</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33059051">pmid:33059051</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cyvr77m4nbhhjah4svlsbzivwu">fatcat:cyvr77m4nbhhjah4svlsbzivwu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210428140819/https://discovery.ucl.ac.uk/id/eprint/10113288/1/1-s2.0-S1053811920309320-main.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ad/af/adafa21400bbd6834542729ee517c225b3458bc3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2020.117447"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a>

Deep Brain Stimulation and L-DOPA Therapy: Concepts of Action and Clinical Applications in Parkinson's Disease

Muthuraman Muthuraman, Nabin Koirala, Dumitru Ciolac, Bogdan Pintea, Martin Glaser, Stanislav Groppa, Gertrúd Tamás, Sergiu Groppa
<span title="2018-08-27">2018</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4kchoxo3jrfubkck3y7nfncina" style="color: black;">Frontiers in Neurology</a> </i> &nbsp;
Targeted, selective modulation of brain networks by DBS and pharmacodynamic effects of L-DOPA therapy on the central nervous system are presented.  ...  L-DOPA is still the most effective pharmacological therapy for the treatment of motor symptoms in Parkinson's disease (PD) almost four decades after it was first used.  ...  Beta activity is differentially modulated by adaptive and conventional DBS techniques (126) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fneur.2018.00711">doi:10.3389/fneur.2018.00711</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30210436">pmid:30210436</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6119713/">pmcid:PMC6119713</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xigod4setvbf5pbruz5jayfhpi">fatcat:xigod4setvbf5pbruz5jayfhpi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190307185508/http://pdfs.semanticscholar.org/e566/ccf52f3fece5e538b0523eb4bbab961b0b71.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e5/66/e566ccf52f3fece5e538b0523eb4bbab961b0b71.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fneur.2018.00711"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119713" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A systematic review of MEG-based studies in Parkinson's disease: The motor system and beyond

Lennard I. Boon, Victor J. Geraedts, Arjan Hillebrand, Martijn R. Tannemaat, Maria Fiorella Contarino, Cornelis J. Stam, Henk W. Berendse
<span title="2019-03-07">2019</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wtsn7qcbmrhjppax2iuhu4xj2m" style="color: black;">Human Brain Mapping</a> </i> &nbsp;
Parkinson's disease (PD) is accompanied by functional changes throughout the brain, including changes in the electromagnetic activity recorded with magnetoencephalography (MEG).  ...  In whole-brain studies PD-related oscillatory slowing and decrease in functional connectivity correlated with cognitive decline and less strongly with other markers of disease progression.  ...  Whereas dopaminergic treatment mainly affected low-beta spectral power in the STN, STN-cortical coherence was strongest in the high-beta band frequencies and was not modulated by levodopa (Litvak et al  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/hbm.24562">doi:10.1002/hbm.24562</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30843285">pmid:30843285</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6594068/">pmcid:PMC6594068</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/egsxrjcbc5gdblfjovszb7tp7e">fatcat:egsxrjcbc5gdblfjovszb7tp7e</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200430083620/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6594068&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f1/1c/f11c762be92bc85a11ddd3473d5291771ec1489a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/hbm.24562"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> wiley.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594068" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Levodopa Modulates Functional Connectivity in the Upper Beta Band Between Subthalamic Nucleus and Muscle Activity in Tonic and Phasic Motor Activity Patterns in Parkinson's Disease

Uri E. Ramirez Pasos, Frank Steigerwald, Martin M. Reich, Cordula Matthies, Jens Volkmann, René Reese
<span title="2019-07-02">2019</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/adcuz6lgabeidhngmk32v7egkq" style="color: black;">Frontiers in Human Neuroscience</a> </i> &nbsp;
We analyzed STN spectral power and its coherence with EMG in the context of two different movement paradigms (tonic wrist extension vs. alternating wrist extension and flexion) and the effect of levodopa  ...  Striatal dopamine depletion disrupts basal ganglia function and causes Parkinson's disease (PD).  ...  In order to examine whether dopamine and movement type effect on STN-EMG coherence by parallel, frequency-specific modulation of STN spectral power and EMG activity, the same ROI was employed on trial-averaged  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnhum.2019.00223">doi:10.3389/fnhum.2019.00223</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31312129">pmid:31312129</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6614179/">pmcid:PMC6614179</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/oizycx52tvffrhct5xjyajy3n4">fatcat:oizycx52tvffrhct5xjyajy3n4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200219052816/https://fjfsdata01prod.blob.core.windows.net/articles/files/449169/pubmed-zip/.versions/1/.package-entries/fnhum-13-00223/fnhum-13-00223.pdf?sv=2015-12-11&amp;sr=b&amp;sig=%2FFziER%2FgA8qejq%2FvDCvxmFz6FMorzmOy%2Fndh3vJj4t0%3D&amp;se=2020-02-19T05%3A28%3A45Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fnhum-13-00223.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/82/38/823837a70863d3e0d01278051420363048d59ada.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnhum.2019.00223"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614179" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson's disease

Muthuraman Muthuraman, Manuel Bange, Nabin Koirala, Dumitru Ciolac, Bogdan Pintea, Martin Glaser, Gerd Tinkhauser, Peter Brown, Günther Deuschl, Sergiu Groppa
<span title="2020-11-05">2020</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3yly6om4ynhcta4fdjenhrdk5y" style="color: black;">Brain</a> </i> &nbsp;
These findings demonstrate that clinically effective deep brain stimulation of the subthalamic nucleus differentially modifies different oscillatory activities in a widespread network of cortical and subcortical  ...  The disruption of pathologically enhanced beta oscillations is considered one of the key mechanisms mediating the clinical effects of deep brain stimulation on motor symptoms in Parkinson's disease.  ...  Parts of this research were conducted using the supercomputer Mogon and advisory services offered by Johannes Gutenberg University Mainz (hpc.uni-mainz.de), which is a member of the AHRP and the Gauss  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/brain/awaa297">doi:10.1093/brain/awaa297</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33150359">pmid:33150359</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cntsxbzjpffmpkltnnwas6ddzy">fatcat:cntsxbzjpffmpkltnnwas6ddzy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201112004436/https://watermark.silverchair.com/awaa297.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAArwwggK4BgkqhkiG9w0BBwagggKpMIICpQIBADCCAp4GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMqrPOnzf5lCW1SLwCAgEQgIICb0ptSTKfXPSHFJcfe2AsmA6Rf_uJehR8FgvpxNXS_ShncpsE8__r2pEzWS6ckG7stof7Ixs9oaTf42EhD-Kp2JuloCndhPvn9QxbWrg3iBcWl7iAJ00uWM2r_JzChr9BPTANxI7fFNtC42j9DFk581TygPDWjEoifN-3WXJgrZob8PJBYQcaldNqSJFpMk5UeLByBNnhGM5co1oA2dAebXnjgKWuVGTYBhd3Nnx0qwJy1qjIsJEFvU7uaWl0wbX_VZKXiv2yq7mxgeVlZAc4ljBKJeMPl1B1MB_fslDt4CRfHsMGmtQNWrQuvTsPfziILsDq6H57bAnlqJKvTuZFO3_HCDS5z5He_hEa_gQZB2S6CbgkuaakQP5UXiHFWPrVlxqpJsItE4JOC9DQvyzPoZjnPvgNlGor3xdrbJi-_AzyrlpwoPkxMGP_2FXVj5DQ0yQgwaTQ02VraGWqNkz9p3WBUv8oghG9k-QAxFRrhustrFK1K7TH9SYj54fgTOTp-tq0E7lf2ki6wwPUlNg6tGUDzv5qMa4whKgQYPNpdE5Wy8wWyfn4rUNHNPcSlVZoqVsIBK2sOTL94Oa_CsnRwaZtv7oxMeBGoFeNFkGgK6rUcuO4PyYAdqo1e7wCpRGRsCrqT4xxQSHpcbJV-Wpneluaieeo3fLyFCAtLsAy7_utqW4wMzoxVI-71Xt9ku7p6Lop8ljNnMcRStqQSH2kRnvB5S9m2k51ZTL4bbfyxhBejC-srrTrHAd-ecuc3WCfw14dunYspZbZkYJ6XvUx1RZq5oecY79KkFuO4xxOI6EE2wwyyG0fbSzNNev3t7Nl" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/32/f8/32f80d6d1d6963ba82a1ba5ddfaf860d4a2bd7be.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/brain/awaa297"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a>

A review of basal ganglia circuits and physiology: Application to deep brain stimulation

Robert S. Eisinger, Stephanie Cernera, Aryn Gittis, Aysegul Gunduz, Michael S. Okun
<span title="2019-01-09">2019</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kypuovuxzffqxdunbutyiqeiqy" style="color: black;">Parkinsonism &amp; Related Disorders</a> </i> &nbsp;
Understanding, re-evaluating, and leveraging the lessons learned from neuromodulation will be crucial to facilitate an increased and improved application of neuromodulation in human disease.  ...  Drawing on the seminal work of DeLong, Albin, and Young, we have now entered an era of basal ganglia neuromodulation.  ...  We thank the Parkinson's Foundation Center of Excellence at the University of Florida, the Tourette  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.parkreldis.2019.01.009">doi:10.1016/j.parkreldis.2019.01.009</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30658883">pmid:30658883</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7020857/">pmcid:PMC7020857</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zcg5a7dcl5bdvjwces5aqxzt5e">fatcat:zcg5a7dcl5bdvjwces5aqxzt5e</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200502095350/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7020857&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/6b/cf/6bcf2db70944a2c975e49c4d50920a73238fb5e5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.parkreldis.2019.01.009"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020857" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Anatomo-Functional Origins of the Cortical Silent Period: Spotlight on the Basal Ganglia

David Zeugin, Silvio Ionta
<span title="2021-05-27">2021</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/5hwrtdnkjvclroyxzt4ty5ijb4" style="color: black;">Brain Sciences</a> </i> &nbsp;
), "indirect" (inhibitory), and "hyperdirect" cortico-subcortical pathways to manage cortical motor inhibition.  ...  This view may help to explain the respective shortening and lengthening of the CSP in various neurological disorders.  ...  Acknowledgments: We thank Gustavo Pamplona for helping us improve the graphical aspects of the present manuscript. Conflicts of Interest: The authors declare no conflict of interest.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/brainsci11060705">doi:10.3390/brainsci11060705</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34071742">pmid:34071742</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/glacwmu7xbd6zjvlyoic7imq54">fatcat:glacwmu7xbd6zjvlyoic7imq54</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210530035020/https://res.mdpi.com/d_attachment/brainsci/brainsci-11-00705/article_deploy/brainsci-11-00705.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/0a/87/0a8704403b2d343e8029a6891478c616173855f4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/brainsci11060705"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a>

Oscillatory Activities in Neurological Disorders of Elderly: Biomarkers to Target for Neuromodulation

Giovanni Assenza, Fioravante Capone, Lazzaro di Biase, Florinda Ferreri, Lucia Florio, Andrea Guerra, Massimo Marano, Matteo Paolucci, Federico Ranieri, Gaetano Salomone, Mario Tombini, Gregor Thut (+1 others)
<span title="2017-06-13">2017</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xyafp6gbr5et3ghi4kqddnyolm" style="color: black;">Frontiers in Aging Neuroscience</a> </i> &nbsp;
Motivated on the one hand by recent evidence that oscillatory activities in neural systems play a role in orchestrating brain functions and dysfunctions, in particular those of neurological disorders specific  ...  We first review the evidence for abnormal oscillatory profiles to be associated with a range of neurological disorders of elderly (e.g., Parkinson's disease (PD), Alzheimer's disease (AD), stroke, epilepsy  ...  In this task, cortical beta activity synchronizes with electromyographic oscillations, as evidenced in the so-called cortico-muscular coherence.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2017.00189">doi:10.3389/fnagi.2017.00189</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28659788">pmid:28659788</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5468377/">pmcid:PMC5468377</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/z5u3ja56kbanbcc3ixepqzxhxy">fatcat:z5u3ja56kbanbcc3ixepqzxhxy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180721114530/https://erepo.uef.fi/bitstream/handle/123456789/5024/fnagi-09-00189.pdf;jsessionid=A256188ED8BB8F03586FEF2EA793412E?sequence=2" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d7/80/d7809abcae8a3fd62369013f957fbae71b9116e9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2017.00189"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468377" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

L-Dopa Modulation of Brain Connectivity in Parkinson's Disease Patients: A Pilot EEG-fMRI Study

Stefania Evangelisti, Francesca Pittau, Claudia Testa, Giovanni Rizzo, Laura Ludovica Gramegna, Lorenzo Ferri, Ana Coito, Pietro Cortelli, Giovanna Calandra-Buonaura, Fabio Bisquoli, Claudio Bianchini, David Neil Manners (+4 others)
<span title="2019-06-14">2019</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wrk3kouosrhcxiprcbguskdipu" style="color: black;">Frontiers in Neuroscience</a> </i> &nbsp;
Studies of functional neurosurgery and electroencephalography in Parkinson's disease have demonstrated abnormally synchronous activity between basal ganglia and motor cortex.  ...  From the EEG data, weighted partial directed coherence was computed in the inverse space after the removal of gradient and cardioballistic artifacts. fMRI results showed that the intake of L-dopa increased  ...  ., 2013) have shown that STN-cortical and cortico-cortical coherence correlate with the severity of parkinsonism and that this coupling was modulated by L-dopa therapy and STN stimulation.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnins.2019.00611">doi:10.3389/fnins.2019.00611</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31258465">pmid:31258465</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6587436/">pmcid:PMC6587436</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xlbdniht7zabpdmi5bkmo3dgpi">fatcat:xlbdniht7zabpdmi5bkmo3dgpi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200215211011/https://pdfs.semanticscholar.org/8299/2518eb2fa213c92f4b3dae7acfbf72d2feb5.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/82/99/82992518eb2fa213c92f4b3dae7acfbf72d2feb5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnins.2019.00611"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587436" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Effect of Parkinson's disease and two therapeutic interventions on muscle activity during walking: a systematic review

Aisha Islam, Lisa Alcock, Kianoush Nazarpour, Lynn Rochester, Annette Pantall
<span title="2020-09-09">2020</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/rsd377ph3vcjjkrafmhd3yqxfi" style="color: black;">npj Parkinson&#39;s Disease</a> </i> &nbsp;
Gait deficits are a common feature of Parkinson's disease (PD) and predictors of future motor and cognitive impairment.  ...  Tibialis anterior was impacted most by the interventions. Quality of the studies was not strong, with a median score of 61%.  ...  ACKNOWLEDGEMENTS A.I. was financially supported by a Barbour Foundation PhD studentship. AUTHOR CONTRIBUTIONS A.P. was responsible for the conception of the systematic review.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41531-020-00119-w">doi:10.1038/s41531-020-00119-w</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32964107">pmid:32964107</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7481232/">pmcid:PMC7481232</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/poj3gfsckndlznjjhimbdrak74">fatcat:poj3gfsckndlznjjhimbdrak74</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201103154210/https://www.pure.ed.ac.uk/ws/files/163718269/s41531_020_00119_w.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/97/5a/975a826de242283c3b7196dc9193f4fbe70bcaf4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41531-020-00119-w"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481232" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Reaching and Grasping Movements in Parkinson's Disease: A Review

Alessio Fasano, Alberto Mazzoni, Egidio Falotico
<span title="2022-03-02">2022</span> <i title="IOS Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/rjfvujhshbbnhe2c6qorj3du6e" style="color: black;">Journal of Parkinson&#39;s Disease</a> </i> &nbsp;
Parkinson's disease (PD) is known to affect the brain motor circuits involving the basal ganglia (BG) and to induce, among other signs, general slowness and paucity of movements.  ...  PD appears to cause impairments not only in movement execution, but also in movement initiation and planning, as revealed by abnormal preparatory activity of motor-related brain areas.  ...  This suggests that BG participate in planning of movement amplitude (or its covariates, such as effort), by modulating cortical activity that prepare the instruction to move and/or by appropriate peri-movement  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jpd-213082">doi:10.3233/jpd-213082</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/35253780">pmid:35253780</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cuwbmrugure5zdz3qngqzs7qqm">fatcat:cuwbmrugure5zdz3qngqzs7qqm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220421073721/https://content.iospress.com/download/journal-of-parkinsons-disease/jpd213082?id=journal-of-parkinsons-disease%2Fjpd213082" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4c/80/4c80f555a5bbcf985e02a1aeb5c4417b51ac226b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jpd-213082"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Impaired reach-to-grasp kinematics in parkinsonian patients relates to dopamine-dependent, subthalamic beta bursts

Matteo Vissani, Chiara Palmisano, Jens Volkmann, Gianni Pezzoli, Silvestro Micera, Ioannis U. Isaias, Alberto Mazzoni
<span title="2021-06-29">2021</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/rsd377ph3vcjjkrafmhd3yqxfi" style="color: black;">npj Parkinson&#39;s Disease</a> </i> &nbsp;
AbstractExcessive beta-band oscillations in the subthalamic nucleus are key neural features of Parkinson's disease.  ...  Here, we show that the movement phases of the reach-to-grasp motor task are coded by the subthalamic bursting activity in a maximally-informative beta high range.  ...  Pozzi and Dr. A. Canessa for their help with data acquisition and analysis. The study was sponsored in part by the "Fondazione Grigioni per il Morbo di Parkinson".  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41531-021-00187-6">doi:10.1038/s41531-021-00187-6</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34188058">pmid:34188058</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/o2ubefrwirffnncouhkbof7kr4">fatcat:o2ubefrwirffnncouhkbof7kr4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210629141346/https://www.nature.com/articles/s41531-021-00187-6.pdf?error=cookies_not_supported&amp;code=d7d7ffda-4bcb-4075-8442-27c5267ec0ce" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/df/30/df3047ec50ffa13c5fffe32df581203804bbea9f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41531-021-00187-6"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Alterations in neuronal activity in basal ganglia-thalamocortical circuits in the parkinsonian state

Adriana Galvan, Annaelle Devergnas, Thomas Wichmann
<span title="2015-02-05">2015</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/aktsba3mwjd3roaiuqkhfjndlq" style="color: black;">Frontiers in Neuroanatomy</a> </i> &nbsp;
In patients with Parkinson's disease and in animal models of this disorder, neurons in the basal ganglia and related regions in thalamus and cortex show changes that can be recorded by using electrophysiologic  ...  network in parkinsonism, and discuss the possible use of this information to optimize treatment approaches to Parkinson's disease, such as deep brain stimulation (DBS) therapy.  ...  ACKNOWLEDGMENTS The authors are supported by research grants from NIH (R01-NS054976, P50-NS071669 and R01-NS071074), and by an NIH infrastructure grant to the Yerkes National Primate Research Center (P51  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnana.2015.00005">doi:10.3389/fnana.2015.00005</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25698937">pmid:25698937</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4318426/">pmcid:PMC4318426</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/a6hureaxobdxdkwaz4vo4i5nou">fatcat:a6hureaxobdxdkwaz4vo4i5nou</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170830084540/https://fjfsdata01prod.blob.core.windows.net/articles/files/124742/pubmed-zip/.versions/1/.package-entries/fnana-09-00005/fnana-09-00005.pdf?sv=2015-12-11&amp;sr=b&amp;sig=jhr6Cg4L266QceutwWzJleOhFZ%2FCDqPWE32gv0Pqd7Y%3D&amp;se=2017-08-30T08%3A45%3A42Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fnana-09-00005.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/58/f7/58f73a65d737551039469021f29db20d2f34469a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnana.2015.00005"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318426" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Electromagnetic mapping of the effects of deep brain stimulation and dopaminergic medication on movement-related cortical activity and corticomuscular coherence in Parkinson's disease [article]

Kousik Sarathy Sridharan, Andreas Højlund, Erik Lisbjerg Johnsen, Niels Aagaard Sunde, Sándor Beniczky, Karen Østergaard
<span title="2019-06-03">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Objectives: To study the effects of DBS and dopaminergic medication treatments on cortical processing and corticomuscular drive during movements.  ...  Our measures of interest were beta (13-30 Hz) corticomuscular coherence (CMC) and low-gamma (31-45 Hz) power.  ...  Acknowledgements 430 We thank our PD patients and healthy controls who participated in the study. We would like to thank  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/657882">doi:10.1101/657882</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fbk7qiylrbezlbamatybx7xhzu">fatcat:fbk7qiylrbezlbamatybx7xhzu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200214044348/https://www.biorxiv.org/content/biorxiv/early/2019/06/03/657882.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/657882"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>
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