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Effects of 3G cell phone exposure on the structure and function of the human cytochrome P450 reductase

Shazia Tanvir, György Thuróczy, Brahim Selmaoui, Viviane Silva Pires Antonietti, Pascal Sonnet, Delia Arnaud-Cormos, Philippe Lévêque, Sylviane Pulvin, René de Seze
2016 Bioelectrochemistry  
CPR plays a key role in the electron transfer to cytochrome P450, which takes part in a wide range of oxidative metabolic reactions in various organisms from microbes to humans.  ...  The relevance of these findings to an actual RF exposure scenario demands further biochemical and in-vivo confirmation.  ...  Author contributions ACCEPTED MANUSCRIPT Effects of cell phone exposure on cytochrome P450 reductase  ... 
doi:10.1016/j.bioelechem.2016.05.005 pmid:27243445 fatcat:joccmchmdbgotfota5bstpznvu

Proof-of-Concept of Electrical Activation of Liposome Nanocarriers: From Dry to Wet Experiments

Laura Caramazza, Martina Nardoni, Annalisa De Angelis, Patrizia Paolicelli, Micaela Liberti, Francesca Apollonio, Stefania Petralito
2020 Frontiers in Bioengineering and Biotechnology  
Finally, a complete characterization of the exposure system is also provided to support the reliability and validity of the study.  ...  The results are supported by multiphysics simulations which consider the coupling of three physics (electromagnetics, thermal and pore kinetics) in order to explain the occurring physical interactions  ...  AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS We thank Elena della Valle and Agnese Denzi for their strong support in the identification of the strengths and weaknesses of the protocol to be applied and Caterina  ... 
doi:10.3389/fbioe.2020.00819 pmid:32793572 pmcid:PMC7390969 fatcat:n4jkh4by4rbhlb7btbighhbkuu

Electromagnetic elds and optomechanics in cancer diagnostics and treatment

Jack A Tuszynski
2018 Frontiers in Bioscience  
Electromagnetic fields, optomechanics and cancer 1392 © 1996-2018 have not been fully understood and exploited in the field of oncology (6, 7).  ...  In vitro effects of electromagnetic fields appear to be related to the type of electromagnetic © 1996-2018 field applied.  ...  There are generally two modeling approaches that have been developed to study microtubule mechanics and vibrations. A continuum mechanics model (72-79) and a discrete model (80-82).  ... 
doi:10.2741/4651 pmid:29293441 fatcat:jet4t4wp2zbdfnr2b2qydbnaxa

2020 Index IEEE Transactions on Magnetics Vol. 56

2020 IEEE transactions on magnetics  
., +, TMAG May 2020 5000106 Modeling of Exposure to Low-Frequency Electromagnetic Fields of Workers in Arbitrary Posture.  ...  ., +, TMAG Nov. 2020 8400308 Modeling of Exposure to Low-Frequency Electromagnetic Fields of Workers in Arbitrary Posture.  ... 
doi:10.1109/tmag.2021.3050874 fatcat:tyv7g6ev3vbotdy7pt5u2aezqq

On-chip mobile microrobotic transducer for high-temporal resolution sensing using dynamics analysis

Hugo Salmon, Laurent Couraud, Gilgueng Hwang
2019 Sensors and Actuators A-Physical  
In these experiments, physical sensing is quantified through microrobot dynamics analysis of its elementary planar motions (rotary and translational) and these results are related to local viscosity of  ...  Here a system is proposed which is fully controllable by calibrated external magnetic fields and high temporal resolution (> 5000F P S) visual feedback.  ...  Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the French National Research Agency.  ... 
doi:10.1016/j.sna.2018.12.043 fatcat:ghix6xkgffghvhcbc6nqacgnke

Nanoparticle-mediated thermal therapy: Evolving strategies for prostate cancer therapy

Sunil Krishnan, Parmeswaran Diagaradjane, Sang Hyun Cho
2010 International Journal of Hyperthermia  
Conclusions-Nanoparticle-mediated thermal therapy is a new and minimally invasive tool in the armamentarium for the treatment of cancers.  ...  or quantify the global concentration and spatial distribution of these particles within tumors, the lack of standardized thermal modeling and dosimetry algorithms, and the concerns regarding their biocompatibility  ...  Acknowledgments We wish to thank David Aten from the medical graphics and photography department at MD Anderson Cancer Center for assistance with preparing figures.  ... 
doi:10.3109/02656736.2010.485593 pmid:20858069 pmcid:PMC3071560 fatcat:wsvegb5qibd7rgzc72lpt4fxn4

Microfabrication of biomedical lab-on-chip devices. A review

A T Giannitsis
2011 Estonian Journal of Engineering  
Lab-on-chip systems are a class of miniaturized analytical devices that integrate fluidics, electronics and various sensorics.  ...  A type of lab-on-chip devices, named biochip, is devoted specifically to genomic, proteomic and pharmaceutical tests.  ...  In order to study the dynamics of a component in a computationally efficient way, it is essential to reduce the number of degrees of freedom, from a three-dimensional model to a two-dimensional model.  ... 
doi:10.3176/eng.2011.2.03 fatcat:umnjnphhjfb4flvvz3yuedu6qu

MEDICAL MAGNETIC RESONANCE (MR) PROCEDURES: PROTECTION OF PATIENTS

2004 Health Physics  
Acknowledgments-The support of the German Federal Environment  ...  For RF decoupling coils operated at frequencies between 64 and 213 MHz, electromagnetic and thermal modeling of SAR and temperature fields in the human leg have been performed by Hand et al. based on a  ...  There are numerous reports of failures of electronic and mechanical medical devices due to electromagnetic interference (EMI) generated by the intense pulsed and static fields emitted by MRI systems.  ... 
doi:10.1097/00004032-200408000-00008 pmid:15257220 fatcat:4m7cakxhlnc5nj2fb6xgr5463e

Computational Fluid-Particle Dynamics Modeling for Unconventional Inhaled Aerosols in Human Respiratory Systems [chapter]

Yu Feng, Zelin Xu, Ahmadreza Haghnegahdar
2016 Aerosols - Science and Case Studies  
The ultimate goal is to establish a roadmap to link different numerical models, and to build the framework of a new multiscale numerical model, which will extend exposure and lung deposition predictions  ...  Case studies for fiber and droplet transport and deposition in lung are also provided. Furthermore, challenges and future directions are discussed to develop next-generation models.  ...  [70] compared the parameter difference between humans and animals and adapted the nasal CFD-PBPK model [71] to perform interspecies variability analyses and sensitivity analyses for vapor exposure  ... 
doi:10.5772/65361 fatcat:su2tpzr4x5e6zbcooxcsb742qy

Stimuli-sensitive fatty acid-based microparticles for the treatment of lung cancer

Katarzyna Reczyńska, Patrycja Marchwica, Dipesh Khanal, Tomasz Borowik, Marek Langner, Elżbieta Pamuła, Wojciech Chrzanowski
2020 Materials Science and Engineering C: Materials for Biological Applications  
SPION and PAX-loaded microparticles (MPs) were fabricated from lauric acid (LAU) and a mixture of myristic and palmitic acids (MYR/PAL) using hot oil-in-water emulsification method.  ...  MPs were spherical in shape with the average particle size between 2 and 3.5 μm and responded to external magnetic field up to the distance of 15 mm. MPs were effectively internalised by the cells.  ...  Kinga Pilelichowska and Dr. Klaudia Król-Morkisz for their help in performing DSC analysis.  ... 
doi:10.1016/j.msec.2020.110801 pmid:32279754 fatcat:wzn6r6be7jbh3nl3jioc32saz4

Electromagnetic Field‐Programmed Magnetic Vortex Nanodelivery System for Efficacious Cancer Therapy

Xiaoli Liu, Yifan Zhang, Yu Guo, Wangbo Jiao, Xiao Gao, Wee Siang Vincent Lee, Yanyun Wang, Xia Deng, Yuan He, Ju Jiao, Ce Zhang, Guoqing Hu (+2 others)
2021 Advanced Science  
Despite the significant potential of magnetic nanovehicles in electromagnetic field (EF)-activated drug delivery, modularizing a tandem magnetoresponsive activity in a one-nanoparticle system to meet different  ...  Herein, a strategy is described by employing sequential EF frequencies in inducing a succession of magnetoresponses in the magnetic nanovehicles that aims to realize cascaded tissue penetration and nuclear  ...  Results and Discussion Lf-EF Drives the Penetration of DOX-PI/FVIOs Through the Tumor Interstitial Tissue To study the magnetophoretic mobility of PI/FVIOs in vitro, we used a model system consisting  ... 
doi:10.1002/advs.202100950 pmid:34279055 pmcid:PMC8456207 fatcat:qutzqws3vja6xb2e5gslizxnla

Polymer-Based Microfluidic Devices for Pharmacy, Biology and Tissue Engineering

Ahmed Alrifaiy, Olof A. Lindahl, Kerstin Ramser
2012 Polymers  
Design and fabrication of microfluidic systems are discussed with respect to specific biological concerns, such as biocompatibility and cell viability.  ...  Recent applications and developments on genetic analysis, cell culture, cell manipulation, biosensors, pathogen detection systems, diagnostic devices, high-throughput screening and biomaterial synthesis  ...  In another study, microfluidic systems have been used as in vitro models for investigation of the role of blood cells in hematological diseases [372, 373] .  ... 
doi:10.3390/polym4031349 fatcat:hup44iv7d5fczdpissu3cpwley

An Intravascular Magnetic Catheter Enables the Retrieval of Nanoagents from the Bloodstream

Veronica Iacovacci, Leonardo Ricotti, Edoardo Sinibaldi, Giovanni Signore, Fabio Vistoli, Arianna Menciassi
2018 Advanced Science  
[32, 33] In vitro validation revealed that the proposed solution is suitable for the devised application and that the developed FEM model represents a reliable tool to guide system design.  ...  To this purpose, a fluidic circuit connected to a micropump (M100 series, TCS) and a blood resembling solution (42% v/v glycerol in water [31] ) were used.  ...  In the previous equations, µ 0 is the magnetic vacuum permeability, χ f and χ p are the magnetic susceptibility of fluid and particles, respectively, η f is the fluid dynamic viscosity, V mag is the volume  ... 
doi:10.1002/advs.201800807 pmid:30250809 pmcid:PMC6145422 fatcat:g3bnnnvp7fd6nm7dg7tm6jensq

The Impact of Bilayer Rigidity on the Release from Magnetoliposomes Vesicles Controlled by PEMFs

Jordan Trilli, Laura Caramazza, Patrizia Paolicelli, Maria Antonietta Casadei, Micaela Liberti, Francesca Apollonio, Stefania Petralito
2021 Pharmaceutics  
Three kinds of MLs are produced with an increasing rigidity of the bilayer, defined as Liquid Disorder, Liquid Order, and Gel MLs and the delivery of a hydrophilic dye (as a model drug) is investigated  ...  Stimuli-sensitive nanocarriers have recently been developed as a powerful tool in biomedical applications such as drug delivery, detection, and gene transfer techniques.  ...  Acknowledgments: The authors are grateful to Ruggero Cadossi and Stefania Setti for the I-ONE pulse generator (Igea, Carpi, Italy).  ... 
doi:10.3390/pharmaceutics13101712 pmid:34684003 fatcat:hvt4iatewfgqbgcqjsnpvrmkn4

Microfluidic Bioreactors for Cell Culturing: A Review

Godfrey Pasirayi, Vincent Auger, Simon M. Scott, Pattanathu K.S.M. Rahman, Meez Islam, Liam O'Hare, Zulfiqur Ali
2011 Micro and Nanosystems  
Microfluidic bioreactor systems have length scales that are well matched to the physical dimensions of most cells and microorganisms.  ...  In view of this, microfluidic bioreactors have attractive features which make them ideal to study the behaviour of cells and their internal organisation in their native microenvironment.  ...  Such physical models can be used as alternative methods to predict human response by exposure to chemicals or pharmaceuticals [252] .  ... 
doi:10.2174/1876402911103020137 fatcat:y3viivrc4bbfdmxm33b7cxcusm
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