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Use of Machine Learning to Determine Deviance in Neuroanatomical Maturity Associated With Future Psychosis in Youths at Clinically High Risk

Yoonho Chung, Jean Addington, Carrie E. Bearden, Kristin Cadenhead, Barbara Cornblatt, Daniel H. Mathalon, Thomas McGlashan, Diana Perkins, Larry J. Seidman, Ming Tsuang, Elaine Walker, Scott W. Woods (+3 others)
<span title="2018-09-01">2018</span> <i title="American Medical Association (AMA)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/dysoj6ukqzbmnecr2bnq4lry3m" style="color: black;">JAMA psychiatry</a> </i> &nbsp;
DESIGN, SETTING, AND PARTICIPANTS In this prospective longitudinal multicenter study, a neuroanatomical-based age prediction model was developed using a supervised machine learning technique with T1-weighted  ...  39 who developed psychosis) and 109 healthy controls 12 to 21 years of age from the North American Prodrome Longitudinal Study 2 (NAPLS 2) for external validation and clinical application.  ...  To do so, we revisited the longitudinal data 14 and plotted annualized rates of change in these neuroanatomical structures as a function of age at the time of the baseline scan.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1001/jamapsychiatry.2018.1543">doi:10.1001/jamapsychiatry.2018.1543</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29971330">pmid:29971330</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6142910/">pmcid:PMC6142910</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/yuyo6pktwvgjxp34llw7ummiga">fatcat:yuyo6pktwvgjxp34llw7ummiga</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200505105310/https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2686140/jamapsychiatry_chung_2018_oi_180040.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d8/7e/d87ed46243831646d44d9bd30d28b96429132df4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1001/jamapsychiatry.2018.1543"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142910" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Intellectual ability and cortical development in children and adolescents

P. Shaw, D. Greenstein, J. Lerch, L. Clasen, R. Lenroot, N. Gogtay, A. Evans, J. Rapoport, J. Giedd
<span title="">2006</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/drfdii35rzaibj3aml5uhvr5xm" style="color: black;">Nature</a> </i> &nbsp;
We examined the thickness of the cortex throughout the entire cerebrum, as it is a sensitive index of normal brain development 5,13 , using a fully automated technique, and have validated these measurements  ...  We characterized brain development from childhood to adulthood in a large group of typically developing subjects (n ¼ 307), the majority of who had prospectively acquired repeated neuroanatomic scans (  ...  We examined the thickness of the cortex throughout the entire cerebrum, as it is a sensitive index of normal brain development 5, 13 , using a fully automated technique, and have validated these measurements  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/nature04513">doi:10.1038/nature04513</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/16572172">pmid:16572172</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/b4whjjgbbrbwdbd2erjrhlsqfi">fatcat:b4whjjgbbrbwdbd2erjrhlsqfi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20160313153430/http://www.fed.cuhk.edu.hk/%7Elchang/material/Evolutionary/IQ%20and%20cortical%20thickness.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/48/35/48357eaa6dd8e31536316d7006c32e6a66e36ccb.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/nature04513"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> nature.com </button> </a>

Imaging the developing brain: what have we learned about cognitive development?

B CASEY, N TOTTENHAM, C LISTON, S DURSTON
<span title="">2005</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/2gvktplqc5gm7mwsea6qgdwy4m" style="color: black;">Trends in Cognitive Sciences</a> </i> &nbsp;
Brain regions associated with more basic functions such as sensory and motor processes mature first, followed by association areas involved in top-down control of behavior.  ...  We review the imaging literature on the neurobiology of cognitive development, focusing specifically on cognitive taskdependent changes observed in brain physiology and anatomy across childhood and adolescence  ...  Acknowledgements This work was supported in part by P01 MH62196, R01 MH63255 and R21 DA15882 to B.J.C.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.tics.2005.01.011">doi:10.1016/j.tics.2005.01.011</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/15737818">pmid:15737818</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ato3ldawsbdlpk2zyflt7xj7qe">fatcat:ato3ldawsbdlpk2zyflt7xj7qe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809030757/https://www.sacklerinstitute.org/cornell/people/bj.casey/publications/publications/Casey.et.al.TICS.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/da/92/da9296364ff902859e6956527f24aa2e2b163793.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.tics.2005.01.011"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Neuroanatomical Assessment of Biological Maturity

Timothy T. Brown, Joshua M. Kuperman, Yoonho Chung, Matthew Erhart, Connor McCabe, Donald J. Hagler, Vijay K. Venkatraman, Natacha Akshoomoff, David G. Amaral, Cinnamon S. Bloss, B.J. Casey, Linda Chang (+10 others)
<span title="">2012</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/waxwzq3cnbet3cmwccpuk4bel4" style="color: black;">Current Biology</a> </i> &nbsp;
Capitalizing on key advances in multisite, multimodal MRI, and using cross-validated nonlinear modeling, we demonstrate that developmental brain phase can be assessed with much greater precision than has  ...  Although much work has described isolated features of neuroanatomical development, it remains a critical challenge to characterize the multidimensional nature of brain anatomy, capturing different phases  ...  Data used in preparation of this study were obtained from the Pediatric Imaging, Neurocognition, and Genetics Study (PING) database.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.cub.2012.07.002">doi:10.1016/j.cub.2012.07.002</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22902750">pmid:22902750</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3461087/">pmcid:PMC3461087</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rp4auwimbbezfgrg2y62zxp7hi">fatcat:rp4auwimbbezfgrg2y62zxp7hi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171003123820/http://publisher-connector.core.ac.uk/resourcesync/data/elsevier/pdf/cb9/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDk2MDk4MjIxMjAwNzkzMg%3D%3D.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/16/d7/16d71470eaac246eae361ca6bb3e4bd5d663b2e1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.cub.2012.07.002"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461087" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

How Does Your Cortex Grow?

A. Raznahan, P. Shaw, F. Lalonde, M. Stockman, G. L. Wallace, D. Greenstein, L. Clasen, N. Gogtay, J. N. Giedd
<span title="2011-05-11">2011</span> <i title="Society for Neuroscience"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s7bticdwizdmhll4taefg57jde" style="color: black;">Journal of Neuroscience</a> </i> &nbsp;
Here, by combining these two strategies for the first time and applying SBM in Ͼ1250 longitudinally acquired brain scans from 647 healthy individuals aged 3-30 years, we deconstruct cortical development  ...  Understanding human cortical maturation is a central goal for developmental neuroscience.  ...  We therefore used the largest known longitudinal database of typical brain development to characterize reference maturational trajectories for the diverse brain properties that define CV, and to determine  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1523/jneurosci.0054-11.2011">doi:10.1523/jneurosci.0054-11.2011</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21562281">pmid:21562281</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3157294/">pmcid:PMC3157294</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/x3ifhnu2d5b6pmus2kfhohatmi">fatcat:x3ifhnu2d5b6pmus2kfhohatmi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170131024258/http://www.jneurosci.org/content/jneuro/31/19/7174.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/46/81/46819680870e5d1671aaf66247483481fdb624fa.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1523/jneurosci.0054-11.2011"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157294" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Prenatal growth in humans and postnatal brain maturation into late adolescence

A. Raznahan, D. Greenstein, N. R. Lee, L. S. Clasen, J. N. Giedd
<span title="2012-06-11">2012</span> <i title="Proceedings of the National Academy of Sciences"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nvtuoas5pbdsllkntnhizy4f4q" style="color: black;">Proceedings of the National Academy of Sciences of the United States of America</a> </i> &nbsp;
Here, we combine the power of a withinmonozygotic twin study design with longitudinal neuroimaging methods that parse dissociable components of structural brain development between ages 3 and 30 y, to  ...  P renatal life encompasses a foundational and universally critical phase of human brain development.  ...  We thank the participants who took part in this study and their families. We thank Prof. Daniel Geschwind for helpful comments during our early formulations of the analyses presented in this paper.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.1203350109">doi:10.1073/pnas.1203350109</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22689983">pmid:22689983</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3396505/">pmcid:PMC3396505</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/atidbgcevnez5pezi7tytpwiem">fatcat:atidbgcevnez5pezi7tytpwiem</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180727045348/http://www.pnas.org/content/pnas/109/28/11366.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d2/0e/d20eb11545d0da342fbd5f3e71c1424fe8a8d42c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.1203350109"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396505" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

S184. MACHINE LEARNING REVEALS DEVIANCE IN NEUROANATOMICAL MATURITY PREDICTIVE OF FUTURE PSYCHOSIS IN YOUTH AT CLINICAL HIGH RISK

Yoonho Chung, Jean Addington, Carrie Bearden, Kristen Cadenhead, Barbara Cornblatt, Daniel Mathalon, Thomas McGlashan, Diana Perkins, Larry Seidman, Ming Tsuang, Elaine Walker, Scott Woods (+3 others)
<span title="2018-04-01">2018</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/o67mrs6u45fmrmhkxo62gcvrli" style="color: black;">Schizophrenia Bulletin</a> </i> &nbsp;
risk of transitioning to a psychotic disorder with persistence of PEs and our findings may reflect the neuroanatomical basis for an anomalous developmental trajectory related to psychotic disorders.  ...  These pilot data are, uniquely, unconfounded by illness and treatment related factors and highlight the continued need for longitudinal assessments of brain structure in relation to PEs; there is an increasing  ...  Methods: A neuroanatomical-based age prediction model was trained using a supervised machine learning technique with T1 MRI scans from 953 typically developing healthy controls (HC) from the Pediatric  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/schbul/sby018.971">doi:10.1093/schbul/sby018.971</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/majxscjuyff5rbdv2aztavctx4">fatcat:majxscjuyff5rbdv2aztavctx4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180724093630/https://dash.harvard.edu/bitstream/handle/1/37067757/5888296.pdf?sequence=1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ea/83/ea83d49ea84f9e701e55cbbbfd5fd70a18d62fbd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/schbul/sby018.971"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a>

Altered cortical thickness development in 22q11.2 deletion syndrome and association with psychotic symptoms

Joëlle Bagautdinova, Daniela Zöller, Marie Schaer, Maria Carmela Padula, Valentina Mancini, Maude Schneider, Stephan Eliez
<span title="2021-07-12">2021</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ywuy2l3c7ngernsmmsbttqvzna" style="color: black;">Molecular Psychiatry</a> </i> &nbsp;
With a high prevalence of psychosis, 22q11.2 deletion syndrome (22q11DS) is a neurogenetic disorder that represents a unique opportunity to examine brain maturation in high-risk individuals.  ...  In this study, we quantified trajectories of CT maturation in 22q11DS and examined the association of CT development with the emergence of psychotic symptoms.  ...  FUNDING This work is supported by the National Center of Competence in Research (NCCR) Synapsy-the Synaptic Bases of Mental Diseases (SNCF, Grant number: 51AU40_125759), and by grants of the Swiss National  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41380-021-01209-8">doi:10.1038/s41380-021-01209-8</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34253864">pmid:34253864</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8873018/">pmcid:PMC8873018</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mcx3iicftbhn5megopsnwcmwti">fatcat:mcx3iicftbhn5megopsnwcmwti</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220224163645/https://www.nature.com/articles/s41380-021-01209-8.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/25/c2/25c29cf7c0b36914ec28d50f0f0ee1fa8af2045f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41380-021-01209-8"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873018" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

S185. DTNBP1 IS ASSOCIATED WITH THE AGE AT ONSET OF KOREAN PATIENTS WITH SCHIZOPHRENIA

Kyuyoung Lee, Eun-jeong Joo
<span title="2018-04-01">2018</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/o67mrs6u45fmrmhkxo62gcvrli" style="color: black;">Schizophrenia Bulletin</a> </i> &nbsp;
Methods: A neuroanatomical-based age prediction model was trained using a supervised machine learning technique with T1 MRI scans from 953 typically developing healthy controls (HC) from the Pediatric  ...  Therefore, in this study, we investigated whether the timing of the appearance or course of the deviation from normal brain maturation, as determined using a machine learning algorithm trained on structural  ...  From the EEG activity, the Small World index (SW, a measure of network efficiency) was calculated as the coefficient between clustering coefficient (CLC, a measure of network segregation) and path length  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/schbul/sby018.972">doi:10.1093/schbul/sby018.972</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ccpstvswtnfb5h76elqap3cony">fatcat:ccpstvswtnfb5h76elqap3cony</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180727135150/https://watermark.silverchair.com/sby018.972.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAdkwggHVBgkqhkiG9w0BBwagggHGMIIBwgIBADCCAbsGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMo5p7E_wLTcf9vviOAgEQgIIBjOz8ca4V_D1xtv01b37cUnUSgroKaYgTMpxaHM7r21CIPfQqzs9ThGTOAz-8iQTJJ-pe9gLEp8ZHvxgpYw7vwmohsMYsB5QtQ5pxX0vhvgqDWNV5VauPDEWA0DsxrOhKhYfy1FSRkqZkNeBYeUxKAHsxooRjijCw4f7YpyE5QFO6fdzy1vQ3MOtrHM6gC8OckT1KOZo9ZLug8dF42H-IM8vMCg1Wl8H5YuK-EkUVSgvByRAuhS43BvwgPqHo92AQiUMtFo58rqWukKT_TpTGAmHDTWaIls6Ca0b8rnKTSVclvTxaMWOHDY-3xYsO5VmVZ2Psr6VrgpJhuhMHqVf6NmJIa2UmAHEnxU0kX3Uuq9-6d3vWilFdI5x7HlMS9kPX0fBvsH2PR45lhSqFz5IaqZcHBsn8Hia6b3YbkRpXeCE39P2A7YXZZWzmbwqHkrAIlRmAF-jtI0GPVxKTmkEWQXolJHLlOy9Hl6WJcRsTz2h-5loz5M_pbWzo_W9_dD47YFPHEYAd7rraak41QQ" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/89/8a/898a09901b9607cbd6cedf63f1495863e621b4af.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/schbul/sby018.972"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a>

Brain Imaging During the Transition from Psychosis Prodrome to Schizophrenia

Yoonho Chung, Tyrone D. Cannon
<span title="">2015</span> <i title="Ovid Technologies (Wolters Kluwer Health)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4klogh22qjgqbg7cqb4bplt6nu" style="color: black;">Journal of Nervous and Mental Disease</a> </i> &nbsp;
We conclude with a consideration of potential mechanisms underlying progressive tissue changes during the prodromal phase of schizophrenia and implications for prevention.  ...  This article reviews recent work bearing on the question of the timing of onset and course of brain changes, focusing on structural MRI, diffusion tensor imaging, and resting state connectivity MRI, in  ...  gray matter that is part of normative adolescent brain development and may thus be obscured by sample differences in age, sex and other factors that influence brain maturation.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/nmd.0000000000000286">doi:10.1097/nmd.0000000000000286</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25900551">pmid:25900551</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4414922/">pmcid:PMC4414922</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/k4fl6hbgtvggbbxvm2ejwadyd4">fatcat:k4fl6hbgtvggbbxvm2ejwadyd4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200428103354/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4414922&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/58/ef/58ef4de69692c9641aa3b3426b473ee528ce4f94.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/nmd.0000000000000286"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414922" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Detailing neuroanatomical development in late childhood and early adolescence using NODDI

Alyssa Mah, Bryce Geeraert, Catherine Lebel, Alexander Leemans
<span title="2017-08-17">2017</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
We used measures from NODDI and DTI to examine white and subcortical gray matter development in a group of 27 healthy participants aged 8-13 years.  ...  Neurite orientation dispersion and density imaging (NODDI) can be used to further characterize development in white and subcortical grey matter regions in the brain by improving specificity of the MRI  ...  Using NODDI and data-driven clustering, we can better characterize developmental changes during this period including regional variation, ultimately providing a better understanding of normal brain maturation  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0182340">doi:10.1371/journal.pone.0182340</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28817577">pmid:28817577</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5560526/">pmcid:PMC5560526</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3ojbcfmcfzhufl442am6rkpcpe">fatcat:3ojbcfmcfzhufl442am6rkpcpe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180725083614/http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182340&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/bc/72/bc7282e1c013cf348cd5f88cd6c7c2636f12e67b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0182340"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560526" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Altered Brain Structure-Function Relationships Underlie Executive Dysfunction in 22q11.2 Deletion Syndrome

Rachel K. Jonas, Maria Jalbrzikowski, Caroline A. Montojo, Arati Patel, Leila Kushan, Carolyn C. Chow, Therese Vesagas, Carrie E. Bearden
<span title="">2015</span> <i title="S. Karger AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/gbpg53oxw5drvijvgljiowqxn4" style="color: black;">Molecular Neuropsychiatry</a> </i> &nbsp;
Our findings suggest that executive dysfunction characteristic of 22q11DS is underscored by altered prefrontal cortical structure.  ...  Prospective longitudinal studies are now underway in order to examine trajectories of both behavioral and neuroanatomic changes.  ...  Each scan began with a 10-min acquisition of standard images used for determining regional anatomy, including a sagittal localizer image (TR/TE = 500/10 ms, 192 × 256 matrix), a high-resolution T2-weighted  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000441979">doi:10.1159/000441979</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27606315">pmid:27606315</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4996003/">pmcid:PMC4996003</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mea4eiin3vcidi2sovqjjfsepa">fatcat:mea4eiin3vcidi2sovqjjfsepa</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190218110835/http://pdfs.semanticscholar.org/0b2c/98ee4fd45e8914de14cd33514b15edbbdce3.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/0b/2c/0b2c98ee4fd45e8914de14cd33514b15edbbdce3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000441979"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996003" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Developmental Trajectories of the Fronto-Temporal Lobes from Infancy to Early Adulthood in Healthy Individuals

Chiaki Tanaka, Mie Matsui, Akiko Uematsu, Kyo Noguchi, Toshio Miyawaki
<span title="">2012</span> <i title="S. Karger AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/rkuqvyvy2je2bh375tzkui4cce" style="color: black;">Developmental Neuroscience</a> </i> &nbsp;
Acknowledgements This study was supported by a Grant-in-Aid for Scientific Research (B) 20330141 and (A) 21243040 from the Japan Society for the Promotion of Science (JSPS) and JSPS Asian Core Program.  ...  Tanaka and Satoshi Uda for their assistance with this work.  ...  We utilized both cross-sectional and longitudinal data to support the validity of the identified developmental trajectories.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000345152">doi:10.1159/000345152</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23257954">pmid:23257954</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/a7vc2i57rzeubfwllzljvaixve">fatcat:a7vc2i57rzeubfwllzljvaixve</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190220211154/http://pdfs.semanticscholar.org/29aa/d01a37a16d9af0b18ff046149b119120b32a.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/29/aa/29aad01a37a16d9af0b18ff046149b119120b32a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000345152"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Cortical abnormalities in youth at clinical high-risk for psychosis: Findings from the NAPLS2 cohort

Yoonho Chung, Dana Allswede, Jean Addington, Carrie E. Bearden, Kristin Cadenhead, Barbara Cornblatt, Daniel H. Mathalon, Thomas McGlashan, Diana Perkins, Larry J. Seidman, Ming Tsuang, Elaine Walker (+4 others)
<span title="2019-05-23">2019</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/47gmsc3hojdm5kdlgbg4peyvyi" style="color: black;">NeuroImage: Clinical</a> </i> &nbsp;
T1 MRI scans from 378 CHR individuals and 190 healthy controls (HC) from the North American Prodrome Longitudinal Study (NAPLS2) were analyzed.  ...  In a recent machine learning study classifying "brain age" based on cross-sectional neuroanatomical data, clinical high-risk (CHR) individuals were observed to show deviation from the normal neuromaturational  ...  This work was supported by a collaborative U01 award from the National Institute of Mental Health at the National Institutes of Health (MH081902 to TDC; MH081857 to BAC; MH081988 to EW; Acknowledgements  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.nicl.2019.101862">doi:10.1016/j.nicl.2019.101862</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31150956">pmid:31150956</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6541907/">pmcid:PMC6541907</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/bjczmldkaraohdbse5dbvyu2d4">fatcat:bjczmldkaraohdbse5dbvyu2d4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200507191600/https://escholarship.org/content/qt4zx7f074/qt4zx7f074.pdf?t=px9cgh" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8d/e1/8de154f4d0f0b88bf3ec2e093e102a6a9a489a7a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.nicl.2019.101862"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541907" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

What can Cortical Development in Attention-Deficit/Hyperactivity Disorder Teach us About the Early Developmental Mechanisms Involved?

Sara Ambrosino, Patrick de Zeeuw, Lara Marise Wierenga, Sarai van Dijk, Sarah Durston
<span title="2017-07-18">2017</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/eeg67t2wzfd3dpiicxsttg3cxi" style="color: black;">Cerebral Cortex</a> </i> &nbsp;
Therefore, we conducted a longitudinal study of multiple cortical dimensions in a sizable, independent ADHD sample.  ...  As such, studying multiple dimensions may inform us about the developmental origins of ADHD. Furthermore, results from existing longitudinal samples await replication.  ...  Zwart, Sanne Veerhoek, Janna van Belle, and Nathalie Vessaz for their assistance with subject recruitment and acquisition of MRI scans throughout the running time of this study, Yumas Hankouri and René  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/cercor/bhx182">doi:10.1093/cercor/bhx182</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28922857">pmid:28922857</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/c7llajafl5dpjdo6o25p2naehe">fatcat:c7llajafl5dpjdo6o25p2naehe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190427201013/https://openaccess.leidenuniv.nl/bitstream/handle/1887/70260/84430533.pdf?sequence=1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/cc/57/cc579b13a8100788df6b509498163d4a84bcaf75.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/cercor/bhx182"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a>
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