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Developing an Integrated Image Bank and Metadata for Large-scale Research in Cerebrovascular Disease: Our Experience from the Stroke Image Bank Project

Samuel O. Danso, Dominic E. Job, David Rodriguez Gonzalez, David Alexander Dickie, Jeb Palmer, Jenny Ure, Philip M. Bath, Peter A. G. Sandercock, Joanna M. Wardlaw
2016 Frontiers in ICT  
Developing an integrated image bank and metadata for large scale research in cerebrovascular disease: our experience from the Stroke Image Bank Project' Frontiers in ICT, vol 3, 32. 2 Danso et al.  ...  Integrated Imagebank for Cerebrovascular Disease Frontiers in ICT | December 2016 | Volume 3 | Article 32 brain imaging clinical and research purposes including developing data analytics  ...  of Marianne and Marcus Wallenberg (Sweden); Foundation for health and cardio-/neurovascular research (Switzerland); the Medical Research Council (UK, grant numbers G0400069 and EME 09-800-15), The Health  ... 
doi:10.3389/fict.2016.00032 fatcat:gtiudtakorew5mmfi5hhxe7jse

Stroke Genetics Network (SiGN) Study: Design and Rationale for a Genome-Wide Association Study of Ischemic Stroke Subtypes

J. F. Meschia, D. K. Arnett, H. Ay, R. D. Brown, O. R. Benavente, J. W. Cole, P. I. W. de Bakker, M. Dichgans, K. F. Doheny, M. Fornage, R. P. Grewal, K. Gwinn (+92 others)
2013 Stroke  
The National Institute of Neurological Disorders and Stroke SiGN includes ischemic stroke cases from 24 genetic research centers: 13 from the United States and 11 from Europe.  ...  Through the Center for Inherited Diseases Research, the Network plans to genotype 10,296 carefully phenotyped stroke cases using genome-wide single nucleotide polymorphism arrays and adds to these another  ...  The SiGN study also includes the following collabora-  ... 
doi:10.1161/strokeaha.113.001857 pmid:24021684 pmcid:PMC4056331 fatcat:c2s3tqu3pzddxbpegeyd5vqxjm

Machine Learning and Deep Learning Approaches for Brain Disease Diagnosis: Principles and Recent Advances

Protima Khan, Md. Fazlul Kader, S. M. Riazul Islam, Aisha B. Rahman, Md. Shahriar Kamal, Masbah Uddin Toha, Kyung-Sup Kwak
2021 IEEE Access  
Thus, because of the variability of brain diseases, existing diagnosis or detection systems are becoming challenging and are still an open problem for research.  ...  Brain is the controlling center of our body. With the advent of time, newer and newer brain diseases are being discovered.  ...  It contains data on different cerebrovascular, neoplastic, degenerative, and inflammatory diseases of the brain. Among those AD, gliomas, and stroke are noteworthy.  ... 
doi:10.1109/access.2021.3062484 fatcat:lmhp34ad3zdexb5y4bt5ksntia

A cross-disease human microglial framework identifies disease-enriched subsets and tool compounds for microglial polarization [article]

John F Tuddenham, Mariko Taga, Verena Haage, Tina Roostaei, Charles White, Annie J. Lee, Masashi Fujita, Anthony Khairallah, Gilad Green, Bradley Hyman, Matthew Frosch, Sarah Hopp (+15 others)
2022 bioRxiv   pre-print
Specific subsets are enriched in susceptibility genes for neurodegenerative diseases or the disease-associated microglial signature.  ...  Finally, we identify and validate candidates for chemically inducing subtype-specific states in vitro, showing that Camptothecin downregulates the transcriptional signature of disease-enriched subsets  ...  Acknowledgements We thank the individuals and their families who donated the brain samples used in this project. The  ... 
doi:10.1101/2022.06.04.494709 fatcat:4k2hsetszberlipartdzfq6eei

9th European Conference on Rare Diseases & Orphan Products (ECRD Vienna 2018)

2018 Orphanet Journal of Rare Diseases  
Assessed RD mortality trends are valuable information for the health authorities in Spain. Acknowledgements Spanish Strategy Action for Health (AESI) supported this research, project No. TPY1238/15.  ...  The authors would like to thank the members of the Spanish Rare Diseases Registries Research Network (Spain RDR) for their invaluable expertise in matters pertaining to the International Classification  ...  The authors would like to thank the members of the Spanish Rare Diseases Registries Research Network (Spain RDR) for their invaluable expertise in matters pertaining to the International Classification  ... 
doi:10.1186/s13023-018-0895-2 fatcat:igrrfshlyjd7jlmdf67xpxzr5m

DeepStroke: An Efficient Stroke Screening Framework for Emergency Rooms with Multimodal Adversarial Deep Learning [article]

Tongan Cai, Haomiao Ni, Mingli Yu, Xiaolei Huang, Kelvin Wong, John Volpi, James Z. Wang, Stephen T.C. Wong
2022 arXiv   pre-print
for patients with suspicion of stroke in an acute setting.  ...  Experiments on our video-audio dataset with actual ER patients show that DeepStroke outperforms state-of-the-art models and achieves better performance than both a triage team and ER doctors, attaining  ...  The authors would like to thank Amber Criswell for her help in patient enrollment and Xiaohui Yu for mobile app development.  ... 
arXiv:2109.12065v2 fatcat:3r5vyturezcpdjdb7i6yelszwm

Cardiovascular rna markers and artificial intelligence may improve covid-19 outcome: position paper from the eu-cardiorna cost action ca17129

Lina Badimon, Emma L Robinson, Amela Jusic, Irina Carpusca, Leon J de Windt, Costanza Emanueli, Péter Ferdinandy, Wei Gu, Mariann Gyöngyösi, Matthias Hackl, Kanita Karaduzovic-Hadziabdic, Mitja Lustrek (+8 others)
2021 Cardiovascular Research  
To face the pandemic and limit its burden, health authorities have launched several fast track calls for research projects aiming to develop rapid strategies to combat the disease, as well as longer-term  ...  projects to prepare for the future.  ...  Hence, the examination of sex differences should be an integral part of COVID-19 directed research projects.  ... 
doi:10.1093/cvr/cvab094 pmid:33839767 pmcid:PMC8083253 fatcat:zhoyffz76rc6dbzud6whagolka

Defeating Alzheimer's disease and other dementias: a priority for European science and society

Bengt Winblad, Philippe Amouyel, Sandrine Andrieu, Clive Ballard, Carol Brayne, Henry Brodaty, Angel Cedazo-Minguez, Bruno Dubois, David Edvardsson, Howard Feldman, Laura Fratiglioni, Giovanni B Frisoni (+22 others)
2016 Lancet Neurology  
Thus, the impact of this terminal disease is already today enormous, and given the predictions for the future, ADOD represents an enormous challenge for any society, and particularly to the ageing European  ...  pathology accounts for the large majority of all dementia cases.  ...  The rural and urban difference in prevalence of dementia and AD is supported by a large scale study from China 83 , suggesting that early experience or exposure to rural living (e.g., low education and  ... 
doi:10.1016/s1474-4422(16)00062-4 pmid:26987701 fatcat:32v43zuvyvb3vlft7rpg7oosyu

Informatics for Health 2017: Advancing both science and practice

Philip J. Scott, Ronald Cornet, Colin McCowan, Niels Peek, Paolo Fraccaro, Nophar Geifman, Wouter T. Gude, William Hulme, Glen P. Martin, Richard Williams
2017 Journal of Innovation in Health Informatics  
of the possible, seen in the breadth and depth of our contributions.  ...  We call upon policy makers, research funders and programme leaders to learn from this joined-up approach.  ...  Large scale bio-banking efforts have established cohorts with >100K participants.  ... 
doi:10.14236/jhi.v24i1.939 pmid:28665785 fatcat:fj7cg7o6h5c3hnd5x7b2cfo2te

ijair-volume-6-issue-1-vii-january-march-2019 -HINDUSTAN BOOK.pdf

V. Thamilarasi
This paper experiments various basic image segmentation techniques for Lung Chest X-Ray images  ...  and cerebrovascular disease or strokes.  ...  The existing fraud detection solution was a quite successful one as compared to other banks in Turkey (this, we know from our experiences in other banks).  ... 
doi:10.6084/m9.figshare.20217722.v1 fatcat:l74ihuqhcvdtjomod3zdwzfniu

Health—exploring complexity: an interdisciplinary systems approach HEC2016

Eva Grill, Martin Müller, Ulrich Mansmann
2016 European Journal of Epidemiology  
Therefore, an EDC system for the OMS trial has been developed and integrated into the research infrastructure of the European Network for Cancer Research in Children and Adolescents (ENCCA) project.  ...  In the eStandards project, 19 European case studies reporting from R&D and large-scale eHealth deployment and policy projects were analyzed.  ...  In this context, we obtained P from the Open-Directory Project.  ... 
doi:10.1007/s10654-016-0183-1 pmid:27522353 fatcat:dcl3nbpygvh5fg7keri74h55ie

10th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID)

2019 Pediatric Rheumatology Online Journal  
However, the link between protein prenylation and inflammation in MKD is still far from understood, largely due to the lack of suitable genetic mouse models.  ...  To assess the effect of the mutations on the mevalonate pathway, we measured the accumulation of unprenylated Rab GTPases and Rap1A using an in vitroprenylation assay and western blotting.  ...  Conclusion: We have found 8 DADA2 patients in Japan and identified some novel disease-causing variants.  ... 
doi:10.1186/s12969-019-0313-x fatcat:misxfquo2zaytnsyvldjbn74cy

State of the Art of Audio- and Video-Based Solutions for AAL

Slavisa ALeksic, Michael Atanasov, Jean Calleja Agius, Kenneth Camilleri, Anto Čartolovni, Pau Climent-Pérez, Sara Colantonio, Stefania Cristina, Vladimir Despotovic, Hazım Kemal Ekenel, Ekrem Erakin, Francisco Florez-Revuelta (+27 others)
2022 Zenodo  
They are designed to provide support in daily life in an invisible, unobtrusive and user-friendly manner.  ...  Nevertheless, to ensure the uptake of AAL in society, potential users must be willing to use AAL applications and to integrate them in their daily environments and lives.  ...  Our objective in designing systems is being innovative and improving user experience.  ... 
doi:10.5281/zenodo.6390708 fatcat:6qfwqd2v2rhe5iuu5zgz77ay4i

Abstracts From the 22nd Annual Health Care Systems Research Network Conference, April 13–16, 2016, Atlanta, Georgia

2016 Journal of Patient-Centered Research and Reviews  
Journal of Patient-Centered Research and Reviews ( JPCRR) is a peerreviewed scientific journal whose mission is to communicate clinical and bench research findings, with the goal of improving the quality  ...  We used prospectively collected data to evaluate the associations between anesthesia and risk of dementia or Alzheimer's disease (AD).  ...  A5-3: Universal Screen for Lynch Syndrome in an  ... 
doi:10.17294/2330-0698.1413 fatcat:dvytsofskrh5bb7r2atlpyogmm

Robotic Versus Laparoscopic Surgery for Rectal Cancer: A Comprehensive Review of Oncological Outcomes

Jessica Lam
2021 The Permanente Journal  
Survival data are less mature, but there is also no difference in disease-free or overall survival between the two techniques.  ...  The robotic platform is one of many tools in the arsenal to assist dissection in the low pelvis.  ...  The MS-CQI research collaborative is an improvement and research community of practice comprised of dedicated researchers, clinicians, coordinators, and PwMS.  ... 
doi:10.7812/tpp/21.050 pmid:35348098 pmcid:PMC8782436 fatcat:omoynaudnbecrp7wtxmslgieou
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