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Semi-Automated Detection of Cerebral Microbleeds on 3.0 T MR Images

Hugo J. Kuijf, Manon Brundel, Jeroen de Bresser, Susanne J. van Veluw, Sophie M. Heringa, Max A. Viergever, Geert Jan Biessels, Koen L. Vincken, Yi Wang
2013 PLoS ONE  
Citation: Kuijf HJ, Brundel M, de Bresser J, van Veluw SJ, Heringa SM, et al. (2013) Semi-Automated Detection of Cerebral Microbleeds on 3.0 T MR Images. PLoS ONE 8(6): e66610.  ...  The radial symmetry transform is originally a technique to highlight circular-shaped objects in two-dimensional images.  ...  Acknowledgments We greatly acknowledge the use of MeVisLab (MeVis Medical Solutions AG, Bremen, Germany). [23] The developed software will be made freely available to research partners.  ... 
doi:10.1371/journal.pone.0066610 pmid:23805246 pmcid:PMC3689771 fatcat:giu27zmgbvc2pcg6dygtzcu334

Automated Detection of Cerebral Microbleeds in MR Images: A Two-Stage Deep Learning Approach

Mohammed A. Al-masni, Woo-Ram Kim, Eung Yeop Kim, Young Noh, Dong-Hyun Kim
2020 NeuroImage: Clinical  
Both stages are conducted using the 3D contextual information of microbleeds from the MR susceptibility-weighted imaging (SWI) and phase images.  ...  These findings outperformed results by previously utilized techniques such as 3D fast radial symmetry transform, producing fewer FPavg and lower computational cost.  ...  As presented, most of the previous works adapted the fast radial symmetry transform (FRST) as a candidate detection stage.  ... 
doi:10.1016/j.nicl.2020.102464 pmid:33395960 pmcid:PMC7575881 fatcat:iaeznjv3xnb6xdkrn73elmjwzm

Automated Detection of Cerebral Microbleeds on MR images using Knowledge Distillation Framework [article]

Vaanathi Sundaresan, Christoph Arthofer, Giovanna Zamboni, Andrew G Murchison, Robert A Dineen, Peter M Rothwell, Dorothee P Auer, Chaoyue Wang, Karla L Miller, Benjamin C Tendler, Fidel Alfaro-Almagro, Stamatios N Sotiropoulos (+3 others)
2021 medRxiv   pre-print
Accurate detection of CMBs would help to determine the CMB lesion count and distribution, which would be further useful to understand the clinical impact of CMBs and to obtain quantitative imaging biomarkers  ...  Cerebral microbleeds (CMBs) are associated with white matter damage, various neurodegenerative and cerebrovascular diseases.  ...  Figure 2 : 2 Figure 2: Examples of the final fast radial symmetry transform (FRST) outputs for various image modalities.  ... 
doi:10.1101/2021.11.15.21266376 fatcat:5z6agkfzwbekrfqarj35bq4jny

Perivascular spaces on 7 Tesla brain MRI are related to markers of small vessel disease but not to age or cardiovascular risk factors

Willem H Bouvy, Jaco JM Zwanenburg, Rik Reinink, Laura EM Wisse, Peter R Luijten, L Jaap Kappelle, Mirjam I Geerlings, Geert Jan Biessels
2016 Journal of Cerebral Blood Flow and Metabolism  
We investigated the association of age, vascular risk factors, and imaging markers of SVD with PVS counts on 7 T MRI, in 50 persons aged ! 40.  ...  Cerebral perivascular spaces (PVS) are small physiological structures around blood vessels in the brain.  ...  We would like to gratefully thank EH van der Veen, M Kooistra and all other people involved in the data acquisition of the PREDICT-MR study.  ... 
doi:10.1177/0271678x16648970 pmid:27154503 pmcid:PMC5076789 fatcat:jslfshvzybaqhjem72c5eg52qu

Deep Learning in Medical Image Analysis

Dinggang Shen, Guorong Wu, Heung-Il Suk
2017 Annual Review of Biomedical Engineering  
The computer-assisted analysis for better interpreting images have been longstanding issues in the medical imaging field.  ...  In this article, we introduce the fundamentals of deep learning methods; review their successes to image registration, anatomical/cell structures detection, tissue segmentation, computer-aided disease  ...  For cerebral microbleeds detection in MRI, they designed a cascade framework.  ... 
doi:10.1146/annurev-bioeng-071516-044442 pmid:28301734 pmcid:PMC5479722 fatcat:amn6qgpt6fedzp3zejgi4aw66u

Scientific paper sessions

2009 Neuroradiology  
Anaplastic and large cell MB did not show any distinctive imaging features.  ...  Of the 28 tumors, 21 were located in the region of the 4th ventricle; 7 were found ;5/28 were MBEN; 6/28 were a desmoplastic/ nodular variant; and one was a large cell MB.  ...  MR imaging was performed during the initial 24 hours after onset using a 1.5-T system.  ... 
doi:10.1007/s00234-009-0561-4 fatcat:o5kffdrey5e7pp6rpqpvepbowy

ECR 2011 Book of Abstracts - B - Scientific Sessions

2011 Insights into Imaging  
using Wilcoxon test.  ...  Purpose: To compare the HCC nodule conspicuity during the arterial phase between contrast-enhanced 64-row multidetector CT with bolus tracking and MR imaging with bolus chase.  ...  Cerebral microbleeds can be visualised in up to 40% of patients with MRI scanners at standard field strengths.  ... 
doi:10.1007/s13244-011-0077-4 pmid:23100071 pmcid:PMC3533624 fatcat:lytbu2vohbhhnorjqlpogl77iu

Abstracts of the Annual Conference of the Asia Pacific Stroke Organization (APSO). Hong Kong, August 30–September 1, 2013

2013 Cerebrovascular Diseases  
Conclusions: We proposed the tenth percentile for the most efficient cutoff point for the VCIHS neuropsychological tools for diagnosing VCI in stroke survivors.  ...  She developed gait disturbance and chronic subdural hematoma was detected by CT examination during dabigatran 110mg bid treatment which was continued for the following 6 days.  ...  Komori Background and Objective: RE-LY trial showed that the incidence of intracranial hemorrhage was lower in patients treated with Dabigatran than in those with Warfarin.  ... 
doi:10.1159/000353795 pmid:24008399 fatcat:chh5t5ts55apvmprbmzxv4sdla


2006 Cerebrovascular Diseases  
Results: Massive RLSh (m-RLSh) was detected in 139 patients (36.7%). The mean follow-up was 733±367 days.  ...  The safety and tolerability of NXY-059 in ICH are being studied in the Cerebral Hemorrhage And NXY-059 Treatment (CHANT) trial; a double-blind, multicenter, placebo-controlled, parallel-group Phase IIb  ...  All patients had underwent standardized MR-imaging to detect typical signs of CAD e.g. mural hematoma in the cervical arteries.  ... 
doi:10.1159/000093822 fatcat:zlkvlediy5ea3eepiunfetasjm

ACNP 56th Annual Meeting: Poster Session I, December 4, 2017

2017 Neuropsychopharmacology  
PTSD diagnosis and PTSD symptom severity were determined using the Clinician-Administered PTSD Scale (CAPS).  ...  A growing body of data suggests that dysregulation of the stress axis, including altered glucocorticoid sensitivity and innate immune activity, may act to disrupt glycemic control in trauma-exposed individuals  ...  For the abdominal MR imaging data analysis, we segmented visceral and subcutaneous adipose tissue using a semi automatic macro in ImageJ.  ... 
doi:10.1038/npp.2017.264 pmid:29192265 fatcat:psc2w4azgrbfhjtxe6oxrnsdaq

Robust multi-structure segmentation of magnetic resonance brain images

Christian Ledig, Daniel Rueckert, European Union
Magnetic resonance (MR) imaging is a powerful technique for the non-invasive in-vivo imaging of the human brain.  ...  In this thesis several robust techniques are developed that allow the fully-automatic analysis of MR brain images.  ...  Using these transformations, label maps and corresponding T 1 -weighted MR images are mapped to the space of I tgt .  ... 
doi:10.25560/28959 fatcat:c63ztanfoja7dg7mucveidfggi

On Nature of the Gradient Echo MR Signal and Its Application to Monitoring Multiple Sclerosis

Jie Luo
has recently attracted much attention of the MR community since it manifests superior gray matter/ white matter contrast and sub-cortical contrast, especially at high field (7 T) MRI.  ...  Among them are magnetization transfer contrast imaging (MT), MR spectroscopy (MRS), and Diffusion Tensor Imaging (DTI) but they have not penetrated to clinical arena yet.  ...  In case of 2D imaging, raw data (k-space) is the 2D Fourier transform of the target MR object.  ... 
doi:10.7936/k76971mb fatcat:2m3lcrfnnved7aayuikobqyg3i

Development and Application of Quantitative Gradient-Echo MRI Techniques for Assessment of Iron and Myelin in the Multiple Sclerosis Brain

Ahmed Elkady
We have demonstrated that the use of LFS and QS contrast for lesion iron detection is sensitive, but not sufficiently specific, while the use of lesion dipole signature is specific but not sufficiently  ...  Along with clinical evaluation, Magnetic Resonance Imaging (MRI) is the gold standard modality for diagnosing and monitoring MS, which has been conventionally carried out using T1 and T2weighted pulse  ...  Acknowledgements The author gratefully acknowledges Queen Elizabeth II scholarship support from the Government of Alberta and grant support from the Multiple Sclerosis Society of Canada, the Canadian Institutes  ... 
doi:10.7939/r30k26t2p fatcat:ehgz2xj4vbbshmymt6oia5i2vq