43Matrix metalloproteinase-9 deletion shifts macrophage polarization towards M2 phenotype in aged left ventricles post-myocardial infarction
A Yabluchanskiy, Y Ma, K Deleon-Pennell, Y-F Jin, M Lindsey
2014
Cardiovascular Research
Additionally, MMP-9 deletion resulted in the increase of CD163 in old mice post-MI compared to young null and age-matched WT control groups (all p,0.05; Figure 1 , B), suggesting enhanced M2 polarization ...
We performed permanent occlusion of the left coronary descending artery to induce MI. Mice were sacrificed at day 7 post-MI, and macrophages were isolated from the infarcted area. ...
Additionally, MMP-9 deletion resulted in the increase of CD163 in old mice post-MI compared to young null and age-matched WT control groups (all p,0.05; Figure 1 , B), suggesting enhanced M2 polarization ...
doi:10.1093/cvr/cvu079.3
fatcat:ntub7nsw5zekjoows3qvrdbz6i