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Deformable Mosaicing for Whole-Body MRI [chapter]

Christian Wachinger, Ben Glocker, Jochen Zeltner, Nikos Paragios, Nikos Komodakis, Michael Sass Hansen, Nassir Navab
2008 Lecture Notes in Computer Science  
Therefore, we propose a deformable mosaicing approach, based on the simultaneous registration to linear weighted averages, to correct for distortions in the overlapping area.  ...  Whole-body magnetic resonance imaging is an emerging application gaining vast clinical interest during the last years.  ...  Mosaicing for Whole-body MRI Fig. 4: Stitching of 3 spine volumes.  ... 
doi:10.1007/978-3-540-85990-1_14 fatcat:q24kbcansfhjtksht4hkxkobi4

MRI Composing for Whole Body Imaging [chapter]

B. Glocker, C. Wachinger, J. Zeltner, N. Paragios, N. Komodakis, M. Hansen, N. Navab
2009 Bildverarbeitung für die Medizin 2009  
The method successfully compensates for the distortions and allows to generate high-resolution whole body images. Results on several in-vivo data sets are presented.  ...  Whole-body magnetic resonance imaging is an emerging application gaining vast clinical interest during the last years.  ...  Introduction Whole-body (WB) magnetic resonance imaging (MRI) is becoming a popular clinical tool due to the recent technological advances in MRI, making faster acquisitions possible.  ... 
doi:10.1007/978-3-540-93860-6_85 dblp:conf/bildmed/GlockerWZPKHN09 fatcat:42j4in5v45gfrj55egevo37kmm

A Review of Intrinsic Optical Imaging Serial Blockface Histology (ICI-SBH) for Whole Rodent Brain Imaging

Joël Lefebvre, Patrick Delafontaine-Martel, Frédéric Lesage
2019 Photonics  
In recent years, multiple serial histology techniques were developed to enable whole rodent brain imaging in 3-D.  ...  The paper concludes with a perspective of future developments, calling for a consolidation of the SBH research and development efforts around the world.  ...  This process is repeated until the whole mosaic has been acquired. Following mosaic acquisition, our 2R-SOCT system can perform 40X imaging for the same blockface tissue slice.  ... 
doi:10.3390/photonics6020066 fatcat:qyfjrhymyndrzewigjrogxbbw4

Clinical report: one year of treatment of Proteus syndrome with miransertib (ARQ 092)

Leslie G. Biesecker, Matthew Edwards, Sheridan O'Donnell, Paula Doherty, Thomas MacDougall, Kate Tith, Julia Kazakin, Brian Schwartz
2020 Molecular Case Studies  
Whole-body MRI findings were stable without apparent disease progression. We conclude that 1 yr of treatment with miransertib was beneficial in this case.  ...  A 20-yr-old man with Proteus syndrome (PS) and somatic mosaicism of the AKT1 c.49G > A p.  ...  Acknowledgments The authors thank the patient's foster family for their advocacy.  ... 
doi:10.1101/mcs.a004549 pmid:32014856 pmcid:PMC6996520 fatcat:iak4qbkbsffwri3z7k2rys4i2m

A multimodal computational pipeline for 3D histology of the human brain [article]

Matteo Mancini, Adrià Casamitjana, Loic Peter, Eleanor Robinson, Shauna Crampsie, David L Thomas, Janice L Holton, Zane Jaunmuktane, Juan Eugenio Iglesias
2020 biorxiv/medrxiv   pre-print
We present results on 3D histology reconstruction of a whole human hemisphere.  ...  The pipeline relies on a volumetric MRI scan that serves as undistorted reference, and on an intermediate imaging modality (blockface photography) that bridges the gap between MRI and histology.  ...  to be the same for the MRI and the mosaic of blockface volumes.  ... 
doi:10.1101/2020.02.10.941948 fatcat:mcd5vmr5xbez3dwlprsmh47mw4

Kyphotic deformity of the lumbar spine due to a monostotic fibrous dysplasia of the second lumbar vertebra: a case report and its surgical management

Anna Stocsits, Sara Lener, Pierre Pascal Girod, Anto Abramovič, Claudius Thomé, Sebastian Hartmann
2020 Acta Neurochirurgica  
A 26-year-old patient presented with a progressive osteolytic lesion of the vertebral body L2 and the diagnosis of MFD.  ...  Minimally invasive piecemeal resection with a combined dorsolateral approach showed a favorable clinical and radiological outcome and seems to be a safe and reliable technique for MFD.  ...  Images of the whole body did not revealed any other lesions, so that the diagnosis of a MFD was confirmed.  ... 
doi:10.1007/s00701-020-04531-2 pmid:32808086 fatcat:zyz2nq2x3jdsjokistotohzbvy

Skull Paget's Disease Developing into Chiari Malformation

Fumio OTSUKA, Kenichi INAGAKI, Jiro SUZUKI, Toshio OGURA, Hirofumi MAKINO
2004 Endocrine journal  
Fig. 1 . 1 (A) Bone scintigraphy in the whole body.  ...  Bone scintigraphy using technetium-99 m diphosphonate exhibited specific and remarkable accumulation in the skull through whole body scanning (Fig. 1A) .  ... 
doi:10.1507/endocrj.51.391 pmid:15256789 fatcat:5uehjtnqvbelfay4hfypahtcxq

PET imaging of phosphodiesterase-4 identifies affected dysplastic bone in McCune-Albright syndrome, a genetic mosaic disorder

Lora Deuitch Weidner, Yuichi Wakabayashi, Louise A Stolz, Michael T Collins, Lori Guthrie, Milalynn Victorino, Joyce Chung, William Miller, Sami S Zoghbi, Victor W. Pike, Masahiro Fujita, Robert B Innis (+1 others)
2020 Journal of Nuclear Medicine  
and six for whole-body scans).  ...  Methods: 11C-(R)-rolipram whole-body and brain PET scans were performed in six individuals with MAS (three for brain scans and six for whole-body scans) and nine healthy controls (seven for brain scans  ...  Henter for invaluable editorial assistance.  ... 
doi:10.2967/jnumed.120.241976 pmid:32284396 fatcat:pbx25apfwvck5c4li65kcchiim

Evidence for Concerted and Mosaic Brain Evolution in Dragon Lizards

Daniel Hoops, Marta Vidal-García, Jeremy F.P. Ullmann, Andrew L. Janke, Timothy Stait-Gardner, David A. Duchêne, William S. Price, Martin J. Whiting, J. Scott Keogh
2017 Brain, Behavior and Evolution  
We found evidence for both mosaic and concerted brain evolution in dragons: concerted brain evolution with respect to body size, and mosaic brain evolution with respect to ecomorph.  ...  We assigned each species to an ecomorph based on habitat use and refuge type, then used MRI to measure total and regional brain volume.  ...  Moroney (Nanoscale Group, Western Sydney University) designed the lizard brain holder that made the MRI scanning possible.  ... 
doi:10.1159/000478738 pmid:28869944 fatcat:ffdbe4mbi5eh3obiiaczlbpdpa

Polyostotic Spinal Paget's With Lumbar Kyphotic Deformity: A Case Report And Literature Review

Selvin Prabhakar Vijayan, Christopher Gerber, Anindya Basu, Tosaddeque Hussain, Mona Tiwari, Radhika Mhatre
2022 Journal of Korean Society of Spine Surgery  
A whole body radionucleotide scan was done to rule out any other skeletal lesion. He was started on medical management for Paget's.  ...  (A) MRI sagittal T2 image showing kyphotic deformity with heterogeneous signal, osteolysis and fusion of upper lumbar vertebrae.  ...  Useful radiological investigations for Paget's disease are X-ray, CT, MRI, and bone scan. A bone scan is used to diagnose the extent of the disease spread.  ... 
doi:10.4184/jkss.2022.29.1.10 fatcat:bq5k3gse7vhv3hu45btpg4j2fu

Genotype-phenotype correlation in neurofibromatosis type-1: NF1 whole gene deletions lead to high tumor-burden and increased tumor-growth

Lennart Well, Kimberly Döbel, Lan Kluwe, Peter Bannas, Said Farschtschi, Gerhard Adam, Victor-Felix Mautner, Johannes Salamon
2021 PLoS Genetics  
Sixty-four patients received follow-up MRI examinations (NF1whole gene deletion n = 32/control group n = 32). Whole-body tumor-volumes were semi-automatically assessed (MedX, V3.42).  ...  We retrospectively evaluated 140 whole-body MR examinations of 38 patients with NF1 whole gene deletions (type-1 group: n = 27/atypical group n = 11) and an age- and sex matched collective of 38 NF1-patients  ...  and availability of at least one whole-body MRI examination for volumetry.  ... 
doi:10.1371/journal.pgen.1009517 pmid:33951044 pmcid:PMC8099117 fatcat:4m3irdvgdrfulgrtag4x4wonu4

Segmentation and quantification of adipose tissue by magnetic resonance imaging

Houchun Harry Hu, Jun Chen, Wei Shen
2015 Magnetic Resonance Materials in Physics, Biology and Medicine  
The use of a single slice, a stack of slices across a limited anatomical region, or a whole body protocol is considered.  ...  In this brief review, introductory concepts in animal and human adipose tissue segmentation using proton magnetic resonance imaging (MRI) and computed tomography are summarized in the context of obesity  ...  Such capability will also exploit the richness of 3D whole body MRI.  ... 
doi:10.1007/s10334-015-0498-z pmid:26336839 pmcid:PMC5206913 fatcat:jrx7yujlizdiffcfpnqeizsydm

Segmental overgrowth syndrome due to an activatingPIK3CAmutation identified in affected muscle tissue by exome sequencing

Maria Rasmussen, Lone Sunde, Karen Petra Weigert, Pauline Wilhemina Bogaard, Dorte L. Lildballe
2014 American Journal of Medical Genetics. Part A  
ACKNOWLEDGMENTS We wish to thank the patient for contributing to the report.  ...  Further, the MRIs demonstrated asymmetric facet joints, some being small others being enlarged, as well as deformed intervertebral foramina.  ...  INTRODUCTION Non-cancerous somatic mosaicism for activating mutation in the PIK3CA gene was first reported in CLOVES syndrome.  ... 
doi:10.1002/ajmg.a.36454 pmid:24665065 fatcat:zotm3vpkwjaf3l5gefehsp6jvi

An Efficient Modelling-Simulation-Analysis Workflow to Investigate Stump-Socket Interaction Using Patient-Specific, Three-Dimensional, Continuum-Mechanical, Finite Element Residual Limb Models

Ellankavi Ramasamy, Okan Avci, Beate Dorow, Sook-Yee Chong, Leonardo Gizzi, Günter Steidle, Fritz Schick, Oliver Röhrle
2018 Frontiers in Bioengineering and Biotechnology  
The proposed approach is not only limited to modelling residual limbs but also has applications in predicting the impact of plastic surgery, for detailed forward-dynamics simulations of normal musculoskeletal  ...  S-YC and LG were in charge of the data collection, and GS and FS were in charge of the MRI imaging. OR devised, conceptualised and supervised the project and drafted parts of the manuscript.  ...  The MR Examinations were performed on a 3 T MRI whole body scanner (Magnetom Skyra, Siemens Healthcare, Erlangen, Germany), and the volunteer gave written informed consent prior to the examinations.  ... 
doi:10.3389/fbioe.2018.00126 pmid:30283777 pmcid:PMC6156538 fatcat:el5ttk2np5gkdhup46ps5oywve

Silent Swelling of the Tibia in a 43-year-old Man

Ali Ocguder, Osman Tecimel, Ahmet Firat, Murat Bozkurt
2008 Clinical Orthopaedics and Related Research  
Radiography (Fig. 1) , computed tomography (CT) (Fig. 2) , and MRI (Fig. 3) were performed. To exclude  ...  The pain had been present for 1 year, although he first recognized the swelling 4 months before presentation. There was no history of trauma to the limb.  ...  Acknowledgments The authors thank Ozgur Tosun, MD, and Musturay Karcaaltincaba, MD, for their help in evaluating radiographs and MRI.  ... 
doi:10.1007/s11999-008-0157-z pmid:18273675 pmcid:PMC2584303 fatcat:fzpsxuynznfibcui7uv4abvsxy
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