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Advanced Monte Carlo simulations of emission tomography imaging systems with GATE

David Sarrut, Mateusz Bala, Manuel Bardies, Julien Bert, Maxime Chauvin, Konstantinos Chatzipapas, Mathieu Dupont, Ane Etxebeste, Louise M Fanchon, Sebastien Jan, Gunjan Kayal, Assen S Kirov (+22 others)
2021 Physics in Medicine and Biology  
In this paper, we reviewed the recent developments that have been proposed to simulate modern detectors and provide a comprehensive report on imaging systems that have been simulated and evaluated in GATE  ...  Additionally, some methodological developments that are not specific for imaging but that can improve detector modelling and provide computation time gains, such as Variance Reduction Techniques and Artificial  ...  Acknowledgments The Opengate collaboration would like to warmly thanks the Geant4 collaboration for their great support and fruitful discussions.  ... 
doi:10.1088/1361-6560/abf276 pmid:33770774 fatcat:7hboqolvz5cexnelzhib7euru4

Sensors for Positron Emission Tomography Applications

Jiang, Chalich, Deen
2019 Sensors  
One key limiting factor in the development of efficient and accurate PET systems is the sensor technology in the PET detector.  ...  In this review, we study and discuss the operating principles, key performance parameters, and PET applications for each type of sensor technology with an emphasis on SiPM and CZT detectors—the two most  ...  when the gamma ray hits the detector, the position where the gamma ray hits the detector, and the energy of the gamma ray [19] .  ... 
doi:10.3390/s19225019 pmid:31744258 pmcid:PMC6891456 fatcat:6akb5mswvjayxnlfljo5novjou

High resolution monolithic LYSO detector with 6-layer depth-of-interaction for clinical PET

Mariele Stockhoff, Milan Decuyper, Roel Van Holen, Stefaan Vandenberghe
2021 Physics in Medicine and Biology  
for the event positioning.  ...  The MNN algorithm performed slightly worse with 1.17 mm for the whole detector and 1.13 mm in the centre.  ...  Furthermore, the longer the axial field of view, the more oblique gamma rays will interact with the crystal, leading to parallax errors and decrease in spatial resolution when no depth-of-interaction (  ... 
doi:10.1088/1361-6560/ac1459 pmid:34261049 fatcat:rzywanfljzhgfp7c5zunskkm3u

Abstracts of the Total Body PET conference 2018

2018 EJNMMI Physics  
This step change in performance offers enormous opportunities for molecular imaging to extend its reach and impact in both clinical diagnostics and research.  ...  Further significant increases in effective sensitivity also are possible by increasing the time-of-flight resolution.  ...  Acknowledgements Support for this work includes NIH grants R01 CA206187 and R01 CA170874. We would like to thank Drs. Martin S. Judenhofer and Eric Berg for providing the animal and phantom data.  ... 
doi:10.1186/s40658-018-0218-7 pmid:29956037 pmcid:PMC6023806 fatcat:ecu5ob3twndqbjp25d5r37ugaq

On the structure of dynamic principal component analysis used in statistical process monitoring

Erik Vanhatalo, Murat Kulahci, Bjarne Bergquist
2017 Chemometrics and Intelligent Laboratory Systems  
The first author would like to thank Professor Carlo Fiorini at Department of Electrical Engineering, Politecnico Di Milano, for the introduction to position sensitive gamma detectors. Appendix.  ...  Model-based event estimation with Poisson model Here we derive the maximum-a posteriori (MAP) estimation algorithm for the coordinates of interaction and energy i, j, k, E of gamma photons under the assumption  ...  A third class of methods is based on training neural networks to predict the twodimensional intersection between the gamma ray and the entrance plane of the camera form the array of photo-detector measurements  ... 
doi:10.1016/j.chemolab.2017.05.016 fatcat:ouss4md4n5eg5h4dgdro5pgydm

A machine learning method for fast and accurate characterization of depth-of-interaction gamma cameras

Stefano Pedemonte, Larry Pierce, Koen Van Leemput
2017 Physics in Medicine and Biology  
A third class of methods is based on training neural networks to predict the twodimensional intersection between the gamma ray and the entrance plane of the camera form the array of photo-detector measurements  ...  The discrete forward model of the camera is characterized by the set of expected measurements {l dijk } in detector element d for gamma interaction in (i, j, k).  ... 
doi:10.1088/1361-6560/aa6ee5 pmid:28436919 fatcat:wpeb2jlzgvckrnzkvgabt4cogq

State of the art in total body PET

Stefaan Vandenberghe, Pawel Moskal, Joel S. Karp
2020 EJNMMI Physics  
But for long objects (like body scans), it increases quadratically with scanner length and factors of 10-40 × higher sensitivity are predicted for the long axial FOV scanner.  ...  One of the reasons was the limitations in the available detector technology, which did not yet have sufficient energy resolution, timing resolution or countrate capabilities for fully exploiting the benefits  ...  Acknowledgements The authors would like to thank Maya Akl Abi from Texas AM University at Qatar for providing the NECR plots and Dr.  ... 
doi:10.1186/s40658-020-00290-2 pmid:32451783 fatcat:57h4hxlhefc6tdlbjdh4kbovt4

A proton range telescope for quality assurance in hadrontherapy

D.A. Watts, U. Amaldi, A. Go, Y.-H. Chang, W. Hajdas, S. Iliescu, N. Malakhov, J. Samarati, F. Sauli
2009 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)  
The design for a unit PET detector based on crystal follows the trends in current PET research allowing for the depth-of-interaction (DOI) to be measured as well as the time-of-flight (TOF) between the  ...  In the world today, hadrontherapy is being more and more widely employed for treating patients with non-operable deep-seated or radio-resistant tumours because of its advantage in delivering a highly conformal  ...  The result is that an X-ray or gamma interaction in the crystal produces a large number of electron-hole pairs on a brief timescale (10 −12 s).  ... 
doi:10.1109/nssmic.2009.5402303 fatcat:7mzoyadpe5b65ob6ddphwxrc54

Nuclear Medicine Physics: Review of Advanced Technology

Jungsu S. Oh
2020 Progress in Medical Physics  
Now that deep-learning-based image processing can be incorporated in nuclear medicine image acquisition/processing, the aforementioned fields of nuclear medicine physics face the new era of Industry 4.0  ...  Two major branches of NM imaging Unlike other structural imaging, such as X-ray computerized tomography (CT) or ultrasound, traditional NM imaging (i.e., gamma camera/SPECT) and PET provide images reflecting  ...  Acknowledgements It is a great honor for the author to have this opportunity to write a nuclear medicine physics review article for the 30th Anniversary Series in PMP.  ... 
doi:10.14316/pmp.2020.31.3.81 fatcat:ua2a2myvgvhtvhgdozwg6eaksu

Power pulsing of the CALICE tile hadron calorimeter

Mathias Reinecke
2016 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)  
DUNE consists of an intense neutrino beam fired a distance of 1300 km from Fermilab (near Chicago) to the 40,000 ton Liquid Argon DUNE detector, located deep underground in the Homestake mine.  ...  In this talk I will describe the scientific aims of DUNE, focussing on the experimental challenges in constructing an operating very large liquid argon time projection chamber detectors.  ...  M13B-6: Characterization of 0.5-Mm Lutetium Oxyorthosilicate Detector Arrays for High-Resolution PET Applications Acknowledgments: Research reported in this publication was supported by the National Heart  ... 
doi:10.1109/nssmic.2016.8069748 fatcat:zjgd7dmfdbhntb4kfwdtrlejhi

Innovations in Instrumentation for Positron Emission Tomography

Eric Berg, Simon R. Cherry
2018 Seminars in nuclear medicine  
Our focus is on the technical aspects of PET imaging, specifically detectors and system design, and the opportunity and necessity to move closer to PET systems for diagnostic patient use and in vivo biomedical  ...  PET scanners are commonly integrated with x-ray computed tomography (CT) or magnetic resonance imaging (MRI) scanners in hybrid devices that can provide both molecular imaging (PET) and anatomical imaging  ...  for the impeccable way in which he represented his profession and for his generous spirit.  ... 
doi:10.1053/j.semnuclmed.2018.02.006 pmid:29852942 pmcid:PMC5986096 fatcat:bxdmzqiaqfbaxk77inelcr3ppy

Particle and nuclear physics instrumentation and its broad connections

M. Demarteau, R. Lipton, H. Nicholson, I. Shipsey
2016 Reviews of Modern Physics  
In some cases, entire detectors or technologies developed specifically for particle physics research have been adopted by other fields of research or in commercial applications.  ...  Thus, detector research and development has not only advanced the current state of technology for particle physics, but has often advanced research in other fields of science and has underpinned progress  ...  The MEGAlib (Medium-Energy Gamma-ray Astronomy library) is a set of software tools which are designed to simulate and analyze data of gamma-ray detectors, with a specialization in Compton telescopes.  ... 
doi:10.1103/revmodphys.88.045007 fatcat:43oupgsmfndgdd5yczwvrztdfy

Testing Lepton Flavor Universality and CKM Unitarity with Rare Pion Decays in the PIONEER experiment [article]

PIONEER Collaboration: W. Altmannshofer, H. Binney, E. Blucher, D. Bryman, L. Caminada, S. Chen, V. Cirigliano, S. Corrodi, A. Crivellin, S. Cuen-Rochin, A. Di Canto, L. Doria (+48 others)
2022 arXiv   pre-print
at 1 part in 10^4.  ...  Such precise measurements of BRPB will allow for tests of CKM unitarity in light of the Cabibbo Angle Anomaly and the theoretically cleanest extraction of |V_ud| at the 0.02% level, comparable to the deduction  ...  Acknowledgments References ACKNOWLEDGMENTS This document was prepared by the PIONEER collaboration in coordination with scientific staff members at PSI.  ... 
arXiv:2203.05505v1 fatcat:g56h5flknbeo3cermst7n3zcde

Accelerator Neutrino Neutron Interaction Experiment (ANNIE): Preliminary Results and Physics Phase Proposal [article]

A. R. Back, J. F. Beacom, M. Bergevin, E. Catano-Mur, S. Dazeley, E. Drakopoulou, F. Di Lodovico, A. Elagin, J. Eisch, V. Fischer, S. Gardiner, R. Hatcher (+19 others)
2017 arXiv   pre-print
The R&D mission of the Accelerator Neutrino Neutron Interaction Experiment (ANNIE) is described in detail.  ...  This paper gives preliminary results of the first phase and described the detector design upgrades necessary for the next phase.  ...  There is considerable interest in the international particle physics community in constructing the Theia detector, an advanced optical detector at a deep depth in order to address questions in neutrino  ... 
arXiv:1707.08222v2 fatcat:7f3nqn4xxjhvpdgmmfyaedmeqi

State-of-the-Art Mobile Radiation Detection Systems for Different Scenarios

Luís Marques, Alberto Vale, Pedro Vaz
2021 Sensors  
This study reviews and discusses the research advancements in the field of gamma-ray and neutron measurements using mobile radiation detection systems since the Fukushima nuclear accident.  ...  Gamma cameras and dual-particle cameras are increasingly being used for source location.  ...  Incident radiation (gamma-rays or neutrons) pass through a coded-aperture mask creating an image in a position sensitive detector.  ... 
doi:10.3390/s21041051 pmid:33557104 pmcid:PMC7913838 fatcat:b2bw2jhqifaadbwq5qkwkdgkjm
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