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Deep Fusion Models of Multi-phase CT and Selected Clinical Data for Preoperative Prediction of Early Recurrence in Hepatocellular Carcinoma

Weibin Wang, Qingqing Chen, Yutaro Iwamoto, Panyanat Aonpong, Lanfen Lin, Hongjie Hu, Qiaowei Zhang, Yen-Wei Chen
2020 IEEE Access  
INDEX TERMS Hepatocellular carcinoma, early recurrence, deep learning, multi-phase CT images, clinical data, fusion model.  ...  In this paper, we proposed a deep-learning based prediction model to extract high-level features from the triple-phase CT images and compare its performance with traditional radiomics model and clinical  ...  ACKNOWLEDGMENT (Weibin Wang and Qingqing Chen are co-first authors.)  ... 
doi:10.1109/access.2020.3011145 fatcat:vvw4rpo5ljagze4iyczvth6eda

State of the Art in Artificial Intelligence and Radiomics in Hepatocellular Carcinoma

Anna Castaldo, Davide Raffaele De Lucia, Giuseppe Pontillo, Marco Gatti, Sirio Cocozza, Lorenzo Ugga, Renato Cuocolo
2021 Diagnostics  
While imaging characteristics of HCC are well-defined in the diagnostic phase, challenging cases still occur, and current prognostic and predictive models are limited in their accuracy.  ...  Often HCC develops in a chronic liver disease setting, and early diagnosis as well as accurate screening of high-risk patients is crucial for appropriate and effective management of these patients.  ...  based on AP radiomic signature+ clinical risk factors C-index 0.789 Liu et al. [69] CNN Prediction of PFS of RFA and SR and optimize the treatment selection in very-early and early-stage HCC  ... 
doi:10.3390/diagnostics11071194 fatcat:zmwt7urwinac7bshxcxm6q7doe

Prediction of Microvascular Invasion in Hepatocellular Carcinoma via Deep Learning: A Multi-Center and Prospective Validation Study

Jingwei Wei, Hanyu Jiang, Mengsu Zeng, Meiyun Wang, Meng Niu, Dongsheng Gu, Huanhuan Chong, Yanyan Zhang, Fangfang Fu, Mu Zhou, Jie Chen, Fudong Lyv (+5 others)
2021 Cancers  
Microvascular invasion (MVI) is a critical risk factor for postoperative recurrence of hepatocellular carcinoma (HCC). Preknowledge of MVI would assist tailored surgery planning in HCC management.  ...  In this multicenter study, we aimed to explore the validity of deep learning (DL) in MVI prediction using two imaging modalities—contrast-enhanced computed tomography (CE-CT) and gadoxetic acid-enhanced  ...  Data Availability Statement: The dataset is available for sharing upon request from Jie Tian. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/cancers13102368 pmid:34068972 fatcat:hwxuckjiwbdu5nzu5ouuhq3oxy

Machine-learning analysis of contrast-enhanced CT radiomics predicts recurrence of hepatocellular carcinoma after resection: A multi-institutional study

Gu-Wei Ji, Fei-Peng Zhu, Qing Xu, Ke Wang, Ming-Yu Wu, Wei-Wei Tang, Xiang-Cheng Li, Xue-Hao Wang
2019 EBioMedicine  
Current guidelines recommend surgical resection as the first-line option for patients with solitary hepatocellular carcinoma (HCC); unfortunately, postoperative recurrence rate remains high and there is  ...  Serum alpha-fetoprotein, albumin-bilirubin grade, liver cirrhosis, tumor margin, and radiomics signature were selected for preoperative model; postoperative model incorporated satellite nodules into above-mentioned  ...  Declaration of Competing Interest The authors declare no potential conflicts of interest.  ... 
doi:10.1016/j.ebiom.2019.10.057 pmid:31735556 pmcid:PMC6923482 fatcat:4vutbmk3wzd37bpkdrq53rdote

The Applications of Radiomics in Precision Diagnosis and Treatment of Oncology: Opportunities and Challenges

Zhenyu Liu, Shuo Wang, Di Dong, Jingwei Wei, Cheng Fang, Xuezhi Zhou, Kai Sun, Longfei Li, Bo Li, Meiyun Wang, Jie Tian
2019 Theranostics  
Progress in computational methods, especially in artificial intelligence for medical image process and analysis, has converted these images into quantitative and minable data associated with clinical events  ...  Here, we review the recent methodological developments in radiomics, including data acquisition, tumor segmentation, feature extraction, and modelling, as well as the rapidly developing deep learning technology  ...  For deep learning, it is an end-to-end method without separate steps of feature extraction, feature selection and modelling.  ... 
doi:10.7150/thno.30309 pmid:30867832 pmcid:PMC6401507 fatcat:zlupwckeajdfzgknpqexuuscce

The 4th Asia-Pacific Primary Liver Cancer Expert Meeting

2013 Liver Cancer  
PE-037 Usefulness of Fusion Imaging for the Treatment Evaluation of Radiofrequency Ablation for Hepatocellular Carcinoma verify the usefulness of fusion imaging of pre-and post-RFA CT and MR, which we  ...  PE-012 Histologic Differentiation Predicts the Survival of Patients with Hepatic Resection for Hepatocellular Carcinoma Background: In resection for hepatocellular carcinoma (HCC), patient selection  ...  Background: Liver resection is the treatment of choice for most cases of early stage hepatocellular carcinoma (HCC). However, the recurrence rates of HCC remains high even after curative hepatectomy.  ... 
doi:10.1159/000343846 fatcat:zpomdxbbpngbbhaxiduksoye5e

The 8th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2017). The Art & Science of Conquering Liver Cancer. Singapore, July 14-16, 2017: Abstracts

2017 Liver Cancer  
The clinical guideline for management of HCC in China focuses on early diagnosis, multiple modalities of treatment, and prevention of recurrence and metastasis for HCC.  ...  tissues and peripheral blood in patients with hepatocellular carcinoma (HCC); next-generation sequencing for deep characterization of these distinct tumor-infiltrating leukocytes and RNA expression analysis  ...  OTR-10076 Substaging of Barcelona Clinic Liver Cancer Stage C Hepatocellular Carcinoma with a National-Wide Validation  ... 
doi:10.1159/000478029 fatcat:mq43zbb47jglhhsejx5iudbrwu

Front Matter: Volume 10575

Proceedings of SPIE, Kensaku Mori, Nicholas Petrick
2018 Medical Imaging 2018: Computer-Aided Diagnosis  
The papers in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee.  ...  Please use the following format to cite material from these proceedings: Publication of record for individual papers is online in the SPIE Digital Library.  ...  Contents 02 Dense volumetric detection and segmentation of mediastinal lymph nodes in chest CT images 10575 03 Early detection of lung cancer recurrence after stereotactic ablative radiation therapy  ... 
doi:10.1117/12.2315758 fatcat:kqpt2ugrxrgx7m5rhasawarque

Deep Learning With Radiomics for Disease Diagnosis and Treatment: Challenges and Potential

Xingping Zhang, Yanchun Zhang, Guijuan Zhang, Xingting Qiu, Wenjun Tan, Xiaoxia Yin, Liefa Liao
2022 Frontiers in Oncology  
(medical big data and multitype data and expert knowledge in medical), limitations of data-driven processes (reproducibility and interpretability of studies, different treatment alternatives for various  ...  Furthermore, a summary of the current state-of-the-art applications of this technology in disease diagnosis, treatment response, and prognosis prediction from the perspective of radiology images, multimodality  ...  hepatocellular carcinoma (HCC).  ... 
doi:10.3389/fonc.2022.773840 pmid:35251962 pmcid:PMC8891653 fatcat:3h5tnm3aznb33k5ylkcd6tvs4e

The 6th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2015), Evidence and Consensus on HCC Management. Osaka, Japan, July 3-5, 2015: Abstracts

2015 Liver Cancer  
Yada who provided valuable ultrasound-based TE data. P2-22 VF Map Scores (Virtual Touch Quantification, Fasting Plasma Glucose, Male, Age, Platelets) for Prediction of Hepato-Carcinogenesis  ...  On CT-CT/MR-MR fusion imaging, the numbesr of HCCs in groups I, II, and III were 9, 58, and 5, respectively.  ...  Data from this trial and preclinical data were modelled to identify a recommended phase II dose (RP2D) of tepotinib of 500 mg/day.  ... 
doi:10.1159/000367745 fatcat:cti4zaoytncetoc4oft7l3j65u

Hepatocellular Carcinoma. Eastern and Western Experiences. February 1-2, 2013, Tokyo, Japan

Norihiro Kokudo, Yashihiro Sakamoto
2013 Liver Cancer  
Tumor in S2, 2 cm in diameter, showed early enhancement in the arterial phase and washed out in the late phase of CT images.  ...  Tumor in S8, 4.8 cm in diameter, showed early enhancement with not stained area in the arterial phase, and washed out in the late phase of CT images.  ...  The outcome of liver resection for hepatocellular carcinoma (HCC) has improved because of established techniques and better patient selection.  ... 
doi:10.1159/000343841 fatcat:ejtvxr3v2fberikvecbaarfujy

4th International Kyoto Liver Cancer Symposium: Emerging Strategies to HCC. Kyoto, Japan, June 7-8, 2014: Abstracts

2014 Liver Cancer  
Methods: From The surveillance of hepatocellular carcinoma (HCC) is an established approach to detect early cancers in patients with high risks.  ...  Objective: Almost all guidelines for the management of hepatocellular carcinoma (HCC) recommend B-mode ultrasonography (B-US) as the first-line screening tool in the surveillance of HCC worldwide.  ...  Pancreas: "Isolated Hepatic Perfusion for Extensive Liver Cancers" published in 2007 and Induction Chemotherapy: "Induction Chemotherapy for Hepatocellular Carcinoma" published in 2011 and Radiologic  ... 
doi:10.1159/000343869 fatcat:i6fnr462uffhlba733a4cdzszm

ESGAR 2020 Book of Abstracts

2020 Insights into Imaging  
Purpose: To identify preoperative gadoxetic acid-enhanced-MRI biomarkers for the prediction of early recurrence (2 years) after curative resection for liver imaging reporting and data system (LI-RADS)  ...  SS 13.6 Evaluation of a serum tumour marker-based recurrence prediction model after radiofrequency ablation for very early/early-stage HCC D.H. Lee, J.  ... 
doi:10.1186/s13244-020-00873-8 pmid:32419107 fatcat:jnt6ow5qljejvcyo257fgdwpbe

ESGAR 2015 Book of Abstracts

2015 Insights into Imaging  
Isointensity in bowel wall and/or mesorectal fat was predictive of recurrence.  ...  Aubé; Angers/FR Purpose: Thermo-ablation by radiofrequency is recognized as a curative treatment for early-stage hepatocellular carcinoma (HCC).  ...  S579 SS 16.08 Sloughing of biliary tumor thrombi of hepatocellular carcinoma after chemoembolization H.-C.  ... 
doi:10.1007/s13244-015-0412-2 pmid:26104122 pmcid:PMC4485664 fatcat:pgp6jvdjkjho5mbxei2gi5lvja

Free Oral

2014 HPB  
FO19-08 PREDICTION OF AGGRESSIVENESS IN EARLY-STAGE HEPATOCELLULAR CARCINOMA FOR SELECTION OF SURGICAL RESECTION Suk-won Suh, Kwang-Woong Lee, Jeong-Moo Lee, Youngrol Choi, Nam-Joon Yi and Kyung-Suk Suh  ...  The preoperative SUVmax of FDG PET/CT has been identified the powerful significant prognostic factor for predicting recurrence in malignant tumor.  ...  in patients with hepatocellular carcinoma.  ... 
doi:10.1111/hpb.12229 pmid:23600801 pmcid:PMC3921006 fatcat:gxapgs52mfgalgoekgw6cvjej4
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