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DDMGD: the database of text-mined associations between genes methylated in diseases from different species

Arwa Bin Raies, Hicham Mansour, Roberto Incitti, Vladimir B. Bajic
2014 Nucleic Acids Research  
Using the text mining system DEMGD we developed earlier and additional post-processing, we extracted associations of genes methylated in different diseases from PubMed Central articles and PubMed abstracts  ...  Recent advancements in epigenetics research allow for largescale discoveries of associations of genes methylated in diseases in different species.  ...  (i) Differences in the scopes of the text mining systems: DEMGD extracts associations from all diseases, but MeInfoText is limited to cancer.  ... 
doi:10.1093/nar/gku1168 pmid:25398897 pmcid:PMC4383966 fatcat:rgvsneyfhrdfxbn6tz525qonne

Co-occurrence and Mutual Exclusivity Analysis of DNA Methylation Reveals Distinct Subtypes in Multiple Cancers

Wubin Ding, Guoshuang Feng, Yige Hu, Geng Chen, Tieliu Shi
2020 Frontiers in Cell and Developmental Biology  
Although COME of gene mutations in pan-cancer have been well explored, little is known about the COME of DNA methylation in pan-cancer.  ...  Co-occurrence and mutual exclusivity (COME) of DNA methylation refer to two or more genes that tend to be positively or negatively correlated in DNA methylation among different samples.  ...  DDMGD: the database of text-mined associations between genes methylated in diseases from different species.  ... 
doi:10.3389/fcell.2020.00020 pmid:32064261 pmcid:PMC7000380 fatcat:xfqr6huzcbcbhnt672l2fxpala

Contributions to Computational Methods for Association Extraction from Biomedical Data: Applications to Text Mining and In Silico Toxicology

Arwa B. Raies
The first application is in the domain of text mining aiming at extracting associations between methylated genes and diseases from biomedical literature.  ...  We developed the DDMGD database to provide a comprehensive repository of information related to genes methylated in diseases, gene expression, and disease progression.  ...  Chapter 3 DDMGD: The Database of Text-mined Associations between Genes Methylated in Diseases from Different Species Introduction Epigenetics is the study of changes in genes expression and its relation  ... 
doi:10.25781/kaust-36dz5 fatcat:lfh7g755qfbgnke47tvxhbnhke